Joseph B Duffy

Summary

Affiliation: Indiana University
Country: USA

Publications

  1. ncbi request reprint GAL4 system in Drosophila: a fly geneticist's Swiss army knife
    Joseph B Duffy
    Department of Biology, Indiana University, 1001 E 3rd Street, Bloomington, IN 47405, USA
    Genesis 34:1-15. 2002
  2. pmc Bipartite inhibition of Drosophila epidermal growth factor receptor by the extracellular and transmembrane domains of Kekkon1
    Diego Alvarado
    Department of Biology, Indiana University, Bloomington, Indiana 47405, USA
    Genetics 167:187-202. 2004
  3. ncbi request reprint Comparative analysis of the Kekkon molecules, related members of the LIG superfamily
    Christina M MacLaren
    Department of Biology, Indiana University, Jordan Hall, 1001 E 3rd Street, Bloomington, IN 47405, USA
    Dev Genes Evol 214:360-6. 2004
  4. pmc Conservation of an inhibitor of the epidermal growth factor receptor, Kekkon1, in dipterans
    Frederick A Derheimer
    Department of Biology, Indiana University, Bloomington, Indiana 47405, USA
    Genetics 166:213-24. 2004
  5. doi request reprint Kekkon5 is an extracellular regulator of BMP signaling
    Timothy A Evans
    Department of Biology, Indiana University, Jordan Hall, 1001 E 3d Street, Bloomington, IN 47405, USA
    Dev Biol 326:36-46. 2009
  6. pmc CREB binding protein functions during successive stages of eye development in Drosophila
    Justin P Kumar
    Department of Biology, Indiana University, Bloomington, Indiana 47401, USA
    Genetics 168:877-93. 2004
  7. pmc Knockouts of Kekkon1 define sequence elements essential for Drosophila epidermal growth factor receptor inhibition
    Diego Alvarado
    Department of Biology, Indiana University, Bloomington, Indiana 47405, USA
    Genetics 166:201-11. 2004
  8. ncbi request reprint Creation of a GAL4/UAS-coupled inducible gene expression system for use in Drosophila cultured cell lines
    Kristin M Klueg
    Biology Department, Indiana University, Bloomington, Indiana 47405, USA
    Genesis 34:119-22. 2002
  9. pmc Posterior localization of dynein and dorsal-ventral axis formation depend on kinesin in Drosophila oocytes
    Robert P Brendza
    Department of Biology, Indiana University, Bloomington 47405, USA
    Curr Biol 12:1541-5. 2002
  10. ncbi request reprint Argos mutants define an affinity threshold for spitz inhibition in vivo
    Diego Alvarado
    Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6059, USA
    J Biol Chem 281:28993-9001. 2006

Collaborators

  • JUSTIN KUMAR
  • Diego Alvarado
  • Timothy A Evans
  • Christina M MacLaren
  • Frederick A Derheimer
  • Kristin M Klueg
  • Robert P Brendza
  • Harita Haridas
  • Brandon P Weasner
  • William M Saxton
  • Laura R Serbus
  • Marc A T Muskavitch

Detail Information

Publications10

  1. ncbi request reprint GAL4 system in Drosophila: a fly geneticist's Swiss army knife
    Joseph B Duffy
    Department of Biology, Indiana University, 1001 E 3rd Street, Bloomington, IN 47405, USA
    Genesis 34:1-15. 2002
  2. pmc Bipartite inhibition of Drosophila epidermal growth factor receptor by the extracellular and transmembrane domains of Kekkon1
    Diego Alvarado
    Department of Biology, Indiana University, Bloomington, Indiana 47405, USA
    Genetics 167:187-202. 2004
    ..Together, our results support a model in which the LRRs of Kek1 in conjunction with its juxta/transmembrane region direct association and inhibition of the Drosophila EGFR through interactions with receptor domain V...
  3. ncbi request reprint Comparative analysis of the Kekkon molecules, related members of the LIG superfamily
    Christina M MacLaren
    Department of Biology, Indiana University, Jordan Hall, 1001 E 3rd Street, Bloomington, IN 47405, USA
    Dev Genes Evol 214:360-6. 2004
    ..In addition, we provide support for the general notion that these molecules may share common functions as CAMs, by demonstrating that Kek family members can form homotypic and heterotypic complexes...
  4. pmc Conservation of an inhibitor of the epidermal growth factor receptor, Kekkon1, in dipterans
    Frederick A Derheimer
    Department of Biology, Indiana University, Bloomington, Indiana 47405, USA
    Genetics 166:213-24. 2004
    ..Strikingly, we find that the cytoplasmic domain contains a region with the highest degree of conservation, which we have implicated in EGFR inhibition and dubbed the Kek tail (KT) box...
  5. doi request reprint Kekkon5 is an extracellular regulator of BMP signaling
    Timothy A Evans
    Department of Biology, Indiana University, Jordan Hall, 1001 E 3d Street, Bloomington, IN 47405, USA
    Dev Biol 326:36-46. 2009
    ..Our identification of Kek5 as a modulator of BMP signaling supports the emerging notion that LIG proteins function as diverse regulators of cellular communication...
  6. pmc CREB binding protein functions during successive stages of eye development in Drosophila
    Justin P Kumar
    Department of Biology, Indiana University, Bloomington, Indiana 47401, USA
    Genetics 168:877-93. 2004
    ..We have used a variety of approaches to define the role of CBP in eye development on a cell-by-cell basis...
  7. pmc Knockouts of Kekkon1 define sequence elements essential for Drosophila epidermal growth factor receptor inhibition
    Diego Alvarado
    Department of Biology, Indiana University, Bloomington, Indiana 47405, USA
    Genetics 166:201-11. 2004
    ..Last, our analysis implicates glycine 160 of the second LRR in regulating EGFR binding...
  8. ncbi request reprint Creation of a GAL4/UAS-coupled inducible gene expression system for use in Drosophila cultured cell lines
    Kristin M Klueg
    Biology Department, Indiana University, Bloomington, Indiana 47405, USA
    Genesis 34:119-22. 2002
  9. pmc Posterior localization of dynein and dorsal-ventral axis formation depend on kinesin in Drosophila oocytes
    Robert P Brendza
    Department of Biology, Indiana University, Bloomington 47405, USA
    Curr Biol 12:1541-5. 2002
    ..Alternatively, kinesin I may facilitate cytoplasmic dynein-based anterodorsal forces by repositioning dynein toward microtubule plus ends...
  10. ncbi request reprint Argos mutants define an affinity threshold for spitz inhibition in vivo
    Diego Alvarado
    Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6059, USA
    J Biol Chem 281:28993-9001. 2006
    ..In agreement with previously reported computational studies, our results define an affinity threshold for optimal Argos inhibition of dEGFR signaling during development...