Research Topics
| Bogdan DragneaSummaryAffiliation: Indiana University Country: USA Publications
Research Grants
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Detail Information
Publications
Gold nanoparticles as spectroscopic enhancers for in vitro studies on single virusesBogdan Dragnea
Department of Chemistry and Department of Biology, Indiana University, Bloomington, Indiana 47405, USA
J Am Chem Soc 125:6374-5. 2003....
Time-resolved spectroscopic studies of the AppA blue-light receptor BLUF domain from Rhodobacter sphaeroidesVladimira Dragnea
Department of Biology, Indiana University, Bloomington, Indiana 47405, USA
Biochemistry 44:15978-85. 2005..Dynamics of the AppA photocycle is discussed in view of the currently solved crystallographic structure of AppA...- Core-like particles of an enveloped animal virus can self-assemble efficiently on artificial templatesNancy L Goicochea
Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA
Nano Lett 7:2281-90. 2007..Here we report progress made on the first step: the efficient self-assembly of the alphavirus capsid around a functionalized nanoparticle core... - Synergistic effects of mutations and nanoparticle templating in the self-assembly of cowpea chlorotic mottle virus capsidsStella E Aniagyei
Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA
Nano Lett 9:393-8. 2009..Moreover, the breadth of the nanoparticle-templated capsid size distribution becomes comparable with the wild-type virus size distribution... - Role of surface charge density in nanoparticle-templated assembly of bromovirus protein cagesMarie Christine Daniel
Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA
ACS Nano 4:3853-60. 2010..The current work furnishes evidence of a critical surface charge density for assembly through an analysis aimed at decoupling the surface charge and the core size... 
Effects of amino-acid substitutions in the Brome mosaic virus capsid protein on RNA encapsidationMasarapu Hema
Department of Molecular and Cellular Biochemistry, Indiana University, Bloomington, Indiana 47405, USA
Mol Plant Microbe Interact 23:1433-47. 2010..Furthermore, wild-type BMV RNA1 was found to be more susceptible to nuclease digestion relative to RNA2 as a function of the buffer pH. Other BMV capsid mutants also had altered ratios of packaged RNAs...- Packaging of gold particles in viral capsidsChao Chen
Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA
J Nanosci Nanotechnol 5:2029-33. 2005.... - Quantum dot encapsulation in viral capsidsSuraj K Dixit
Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA
Nano Lett 6:1993-9. 2006.... - Nanoparticle-templated assembly of viral protein cagesChao Chen
Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA
Nano Lett 6:611-5. 2006..Moreover, a pH-induced swelling transition of the VLPs is observed, in direct analogy to the native virus... - Self-assembly of brome mosaic virus capsids: insights from shorter time-scale experimentsChao Chen
Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA
J Phys Chem A 112:9405-12. 2008..To be able to simulate the sharp takeoff from the initial lag phase to the growth phase in the kinetic curves, a monomer activation step was proposed... - Conformationally dynamic π-conjugation: probing structure-property relationships of fluorescent tris(N-salicylideneaniline)sMario Vieweger
Department of Chemistry, Indiana University, Bloomington, Indiana 47405, United States
J Phys Chem A 115:13298-308. 2011.... - The coat protein leads the way: an update on basic and applied studies with the Brome mosaic virus coat proteinC Cheng Kao
Department of Molecular and Cellular Biochemistry, Indiana University, Bloomington, IN 47405, USA
Mol Plant Pathol 12:403-12. 2011..This update summarizes the interaction between the BMV CP and RNAs that can regulate RNA synthesis, translation and RNA encapsidation, as well as the formation of VLPs... - An examination of the electrostatic interactions between the N-terminal tail of the Brome Mosaic Virus coat protein and encapsidated RNAsPeng Ni
Department of Molecular and Cellular Biochemistry, Indiana University, Bloomington, IN 47405, USA
J Mol Biol 419:284-300. 2012..These results experimentally demonstrated the impact of electrostatics and additional restraints in the encapsidation of BMV RNAs, which could be applicable to other viruses... - Self-assembled virus-like particles with magnetic coresXinlei Huang
Department of Chemistry, Indiana University, 800 East Kirkwood Avenue, Bloomington, Indiana 47405, USA
Nano Lett 7:2407-16. 2007..Differences between the two functionalization strategies are discussed... - Structure and stoichiometry of template-directed recombinant HIV-1 Gag particlesNancy L Goicochea
Department of Chemistry, Indiana University, Bloomington, IN 47405, USA
J Mol Biol 410:667-80. 2011..Thus, instead of a holey protein array, the experimental model presented here appears to consist of a continuous array of ∼5000 proteins enveloping the core, in which regular regions are separated by extended areas of disorder... - Magnetic virus-like nanoparticles in N. benthamiana plants: a new paradigm for environmental and agronomic biotechnological researchXinlei Huang
Department of Chemistry, Indiana University, 800 E Kirkwood Avenue, Bloomington, Indiana 47405, United States
ACS Nano 5:4037-45. 2011..These particles potentially open new opportunities for high-contrast functional imaging in plants and for the delivery of therapeutic antimicrobial cores into plants... - The packaging of different cargo into enveloped viral nanoparticlesFan Cheng
Department of Biology, Indiana University, Bloomington, Indiana 47405, United States
Mol Pharm 10:51-8. 2013..We propose that alphaviruses can be selectively modified to create viral nanoparticles for biomedical applications and basic research... - Bio-enabled synthesis of metamaterialsChristopher C DuFort
Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA
Annu Rev Phys Chem 61:323-44. 2010.... - Microfluidic devices integrating microcavity surface-plasmon-resonance sensors: glucose oxidase binding-activity detectionDragos Amarie
Biocomplexity Institute, Department of Physics, Indiana University, Bloomington, Indiana 47405 7102, USA
Anal Chem 82:343-52. 2010..Each MSPRS can detect the binding to its surface of fewer than 35,000 glucose oxidase molecules (representing 9.6 fg or 60 zmol of protein), about 10(6) times fewer than classical surface-plasmon-resonance biosensors... - Photothermal imaging and measurement of protein shell stoichiometry of single HIV-1 Gag virus-like nanoparticlesMario Vieweger
Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA
ACS Nano 5:7324-33. 2011..For the first time, the protein stoichiometry of a single virus-like particle was estimated by a method other than electron microscopy... - Reactivity-based fluoride detection: evolving design principles for spring-loaded turn-on fluorescent probesXuan Jiang
Department of Chemistry, Indiana University, 800 East Kirkwood Avenue, Bloomington, Indiana 47405, USA
Org Lett 9:3579-82. 2007..Selective cleavage of strategically placed Si-O bonds by fluoride ion induces spring-loaded conformational transitions that are tightly coupled to fluorescence enhancement... - LL37 and cationic peptides enhance TLR3 signaling by viral double-stranded RNAsYVONNE LAI
Department of Molecular and Cellular Biochemistry, Indiana University, Bloomington, Indiana, United States of America
PLoS ONE 6:e26632. 2011..It synergizes with TLR2/1, TLR3 and TLR5 agonists to increase IL8 and IL6 production. This work seeks to determine whether LL37 enhances viral dsRNA recognition by TLR3... - Three-dimensional mapping of the light intensity transmitted through nanoaperturesDragos Amarie
Department of Physics, Indiana University, Bloomington, Indiana 47405, USA
Nano Lett 5:1227-30. 2005..This method provides direct visualization of the intensity distribution in close proximity to nanostructures and overcomes limitations imposed by physical probes where the contribution of the probe to the map requires deconvolution... - Bio-inspired materials: unnatural lifeBogdan Dragnea
Nat Mater 7:102-4. 2008
Research Grants
- In vivo imaging and dynamics of single virus-like particlesBogdan Dragnea; Fiscal Year: 2007..We will learn unprecedented basic insight into virus biology. The technology will also broaden the area of future VLP applications and yield a new class of high-output probes that can be adapted to a wide range of targets. ..
- In vivo imaging and dynamics of single virus-like particlesBogdan Dragnea; Fiscal Year: 2009..We will learn unprecedented basic insight into virus biology. The technology will also broaden the area of future VLP applications and yield a new class of high-output probes that can be adapted to a wide range of targets. ..
- In vivo imaging and dynamics of single virus-like particlesBogdan Dragnea; Fiscal Year: 2010..We will learn unprecedented basic insight into virus biology. The technology will also broaden the area of future VLP applications and yield a new class of high-output probes that can be adapted to a wide range of targets. ..