Bogdan Dragnea

Summary

Affiliation: Indiana University
Country: USA

Publications

  1. ncbi request reprint Gold nanoparticles as spectroscopic enhancers for in vitro studies on single viruses
    Bogdan Dragnea
    Department of Chemistry and Department of Biology, Indiana University, Bloomington, Indiana 47405, USA
    J Am Chem Soc 125:6374-5. 2003
  2. pmc Time-resolved spectroscopic studies of the AppA blue-light receptor BLUF domain from Rhodobacter sphaeroides
    Vladimira Dragnea
    Department of Biology, Indiana University, Bloomington, Indiana 47405, USA
    Biochemistry 44:15978-85. 2005
  3. ncbi request reprint Core-like particles of an enveloped animal virus can self-assemble efficiently on artificial templates
    Nancy L Goicochea
    Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA
    Nano Lett 7:2281-90. 2007
  4. pmc Synergistic effects of mutations and nanoparticle templating in the self-assembly of cowpea chlorotic mottle virus capsids
    Stella E Aniagyei
    Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA
    Nano Lett 9:393-8. 2009
  5. pmc Role of surface charge density in nanoparticle-templated assembly of bromovirus protein cages
    Marie Christine Daniel
    Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA
    ACS Nano 4:3853-60. 2010
  6. ncbi request reprint Quantum dot encapsulation in viral capsids
    Suraj K Dixit
    Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA
    Nano Lett 6:1993-9. 2006
  7. ncbi request reprint Packaging of gold particles in viral capsids
    Chao Chen
    Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA
    J Nanosci Nanotechnol 5:2029-33. 2005
  8. doi request reprint Effects of amino-acid substitutions in the Brome mosaic virus capsid protein on RNA encapsidation
    Masarapu Hema
    Department of Molecular and Cellular Biochemistry, Indiana University, Bloomington, Indiana 47405, USA
    Mol Plant Microbe Interact 23:1433-47. 2010
  9. ncbi request reprint Nanoparticle-templated assembly of viral protein cages
    Chao Chen
    Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA
    Nano Lett 6:611-5. 2006
  10. pmc Self-assembly of brome mosaic virus capsids: insights from shorter time-scale experiments
    Chao Chen
    Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA
    J Phys Chem A 112:9405-12. 2008

Collaborators

Detail Information

Publications25

  1. ncbi request reprint Gold nanoparticles as spectroscopic enhancers for in vitro studies on single viruses
    Bogdan Dragnea
    Department of Chemistry and Department of Biology, Indiana University, Bloomington, Indiana 47405, USA
    J Am Chem Soc 125:6374-5. 2003
    ....
  2. pmc Time-resolved spectroscopic studies of the AppA blue-light receptor BLUF domain from Rhodobacter sphaeroides
    Vladimira Dragnea
    Department of Biology, Indiana University, Bloomington, Indiana 47405, USA
    Biochemistry 44:15978-85. 2005
    ..Dynamics of the AppA photocycle is discussed in view of the currently solved crystallographic structure of AppA...
  3. ncbi request reprint Core-like particles of an enveloped animal virus can self-assemble efficiently on artificial templates
    Nancy L Goicochea
    Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA
    Nano Lett 7:2281-90. 2007
    ..Here we report progress made on the first step: the efficient self-assembly of the alphavirus capsid around a functionalized nanoparticle core...
  4. pmc Synergistic effects of mutations and nanoparticle templating in the self-assembly of cowpea chlorotic mottle virus capsids
    Stella E Aniagyei
    Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA
    Nano Lett 9:393-8. 2009
    ..Moreover, the breadth of the nanoparticle-templated capsid size distribution becomes comparable with the wild-type virus size distribution...
  5. pmc Role of surface charge density in nanoparticle-templated assembly of bromovirus protein cages
    Marie Christine Daniel
    Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA
    ACS Nano 4:3853-60. 2010
    ..The current work furnishes evidence of a critical surface charge density for assembly through an analysis aimed at decoupling the surface charge and the core size...
  6. ncbi request reprint Quantum dot encapsulation in viral capsids
    Suraj K Dixit
    Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA
    Nano Lett 6:1993-9. 2006
    ....
  7. ncbi request reprint Packaging of gold particles in viral capsids
    Chao Chen
    Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA
    J Nanosci Nanotechnol 5:2029-33. 2005
    ....
  8. doi request reprint Effects of amino-acid substitutions in the Brome mosaic virus capsid protein on RNA encapsidation
    Masarapu Hema
    Department of Molecular and Cellular Biochemistry, Indiana University, Bloomington, Indiana 47405, USA
    Mol Plant Microbe Interact 23:1433-47. 2010
    ..Furthermore, wild-type BMV RNA1 was found to be more susceptible to nuclease digestion relative to RNA2 as a function of the buffer pH. Other BMV capsid mutants also had altered ratios of packaged RNAs...
  9. ncbi request reprint Nanoparticle-templated assembly of viral protein cages
    Chao Chen
    Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA
    Nano Lett 6:611-5. 2006
    ..Moreover, a pH-induced swelling transition of the VLPs is observed, in direct analogy to the native virus...
  10. pmc Self-assembly of brome mosaic virus capsids: insights from shorter time-scale experiments
    Chao Chen
    Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA
    J Phys Chem A 112:9405-12. 2008
    ..To be able to simulate the sharp takeoff from the initial lag phase to the growth phase in the kinetic curves, a monomer activation step was proposed...
  11. pmc Conformationally dynamic π-conjugation: probing structure-property relationships of fluorescent tris(N-salicylideneaniline)s
    Mario Vieweger
    Department of Chemistry, Indiana University, Bloomington, Indiana 47405, United States
    J Phys Chem A 115:13298-308. 2011
    ....
  12. doi request reprint The coat protein leads the way: an update on basic and applied studies with the Brome mosaic virus coat protein
    C Cheng Kao
    Department of Molecular and Cellular Biochemistry, Indiana University, Bloomington, IN 47405, USA
    Mol Plant Pathol 12:403-12. 2011
    ..This update summarizes the interaction between the BMV CP and RNAs that can regulate RNA synthesis, translation and RNA encapsidation, as well as the formation of VLPs...
  13. pmc An examination of the electrostatic interactions between the N-terminal tail of the Brome Mosaic Virus coat protein and encapsidated RNAs
    Peng Ni
    Department of Molecular and Cellular Biochemistry, Indiana University, Bloomington, IN 47405, USA
    J Mol Biol 419:284-300. 2012
    ..These results experimentally demonstrated the impact of electrostatics and additional restraints in the encapsidation of BMV RNAs, which could be applicable to other viruses...
  14. ncbi request reprint Self-assembled virus-like particles with magnetic cores
    Xinlei Huang
    Department of Chemistry, Indiana University, 800 East Kirkwood Avenue, Bloomington, Indiana 47405, USA
    Nano Lett 7:2407-16. 2007
    ..Differences between the two functionalization strategies are discussed...
  15. pmc Structure and stoichiometry of template-directed recombinant HIV-1 Gag particles
    Nancy L Goicochea
    Department of Chemistry, Indiana University, Bloomington, IN 47405, USA
    J Mol Biol 410:667-80. 2011
    ..Thus, instead of a holey protein array, the experimental model presented here appears to consist of a continuous array of ∼5000 proteins enveloping the core, in which regular regions are separated by extended areas of disorder...
  16. pmc Magnetic virus-like nanoparticles in N. benthamiana plants: a new paradigm for environmental and agronomic biotechnological research
    Xinlei Huang
    Department of Chemistry, Indiana University, 800 E Kirkwood Avenue, Bloomington, Indiana 47405, United States
    ACS Nano 5:4037-45. 2011
    ..These particles potentially open new opportunities for high-contrast functional imaging in plants and for the delivery of therapeutic antimicrobial cores into plants...
  17. doi request reprint The packaging of different cargo into enveloped viral nanoparticles
    Fan Cheng
    Department of Biology, Indiana University, Bloomington, Indiana 47405, United States
    Mol Pharm 10:51-8. 2013
    ..We propose that alphaviruses can be selectively modified to create viral nanoparticles for biomedical applications and basic research...
  18. doi request reprint Bio-enabled synthesis of metamaterials
    Christopher C DuFort
    Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA
    Annu Rev Phys Chem 61:323-44. 2010
    ....
  19. pmc Microfluidic devices integrating microcavity surface-plasmon-resonance sensors: glucose oxidase binding-activity detection
    Dragos Amarie
    Biocomplexity Institute, Department of Physics, Indiana University, Bloomington, Indiana 47405 7102, USA
    Anal Chem 82:343-52. 2010
    ..Each MSPRS can detect the binding to its surface of fewer than 35,000 glucose oxidase molecules (representing 9.6 fg or 60 zmol of protein), about 10(6) times fewer than classical surface-plasmon-resonance biosensors...
  20. doi request reprint Physiochemical Properties of Caulobacter crescentus Holdfast: A Localized Bacterial Adhesive
    Cécile Berne
    Department of Biology, Indiana University, Bloomington, Indiana 47405, United States
    J Phys Chem B 117:10492-503. 2013
    ..A picture emerged in which discrete molecular units called adhesins are responsible for initial holdfast adhesion, by acting in a cooperative manner. ..
  21. pmc Photothermal imaging and measurement of protein shell stoichiometry of single HIV-1 Gag virus-like nanoparticles
    Mario Vieweger
    Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA
    ACS Nano 5:7324-33. 2011
    ..For the first time, the protein stoichiometry of a single virus-like particle was estimated by a method other than electron microscopy...
  22. pmc LL37 and cationic peptides enhance TLR3 signaling by viral double-stranded RNAs
    YVONNE LAI
    Department of Molecular and Cellular Biochemistry, Indiana University, Bloomington, Indiana, United States of America
    PLoS ONE 6:e26632. 2011
    ..It synergizes with TLR2/1, TLR3 and TLR5 agonists to increase IL8 and IL6 production. This work seeks to determine whether LL37 enhances viral dsRNA recognition by TLR3...
  23. ncbi request reprint Reactivity-based fluoride detection: evolving design principles for spring-loaded turn-on fluorescent probes
    Xuan Jiang
    Department of Chemistry, Indiana University, 800 East Kirkwood Avenue, Bloomington, Indiana 47405, USA
    Org Lett 9:3579-82. 2007
    ..Selective cleavage of strategically placed Si-O bonds by fluoride ion induces spring-loaded conformational transitions that are tightly coupled to fluorescence enhancement...
  24. ncbi request reprint Three-dimensional mapping of the light intensity transmitted through nanoapertures
    Dragos Amarie
    Department of Physics, Indiana University, Bloomington, Indiana 47405, USA
    Nano Lett 5:1227-30. 2005
    ..This method provides direct visualization of the intensity distribution in close proximity to nanostructures and overcomes limitations imposed by physical probes where the contribution of the probe to the map requires deconvolution...
  25. doi request reprint Bio-inspired materials: unnatural life
    Bogdan Dragnea
    Nat Mater 7:102-4. 2008

Research Grants4

  1. In vivo imaging and dynamics of single virus-like particles
    Bogdan Dragnea; Fiscal Year: 2007
    ..We will learn unprecedented basic insight into virus biology. The technology will also broaden the area of future VLP applications and yield a new class of high-output probes that can be adapted to a wide range of targets. ..
  2. In vivo imaging and dynamics of single virus-like particles
    Bogdan Dragnea; Fiscal Year: 2009
    ..We will learn unprecedented basic insight into virus biology. The technology will also broaden the area of future VLP applications and yield a new class of high-output probes that can be adapted to a wide range of targets. ..
  3. In vivo imaging and dynamics of single virus-like particles
    Bogdan Dragnea; Fiscal Year: 2010
    ..We will learn unprecedented basic insight into virus biology. The technology will also broaden the area of future VLP applications and yield a new class of high-output probes that can be adapted to a wide range of targets. ..