Research Topics
| Linda DiMeglioSummaryAffiliation: Indiana University Country: USA Publications
Research Grants
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Detail Information
Publications
Bone mineral density in children and adolescents with perinatal HIV infectionLinda A DiMeglio
Section of Pediatric Endocrinology and Diabetology, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA
AIDS 27:211-20. 2013..To estimate prevalence of low bone mineral density (BMD) in perinatally HIV-infected (HIV+) and HIV-exposed but uninfected (HEU) children, and to determine predictors of BMD in HIV+...- Endothelial abnormalities in adolescents with type 1 diabetes: a biomarker for vascular sequelae?Linda A DiMeglio
Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN 46202 5225, USA
J Pediatr 157:540-6. 2010.... 
Bisphosphonate therapy for fibrous dysplasiaLinda A DiMeglio
Section of Pediatric Endocrinology and Diabetology, Rm 5960, 702 Barnhill Drive, Indiana University, School of Medicine, Indianapolis, IN 46208, USA
Pediatr Endocrinol Rev 4:440-5. 2007..Many questions remain about optimizing their use for fibrous dysplasia therapy...- Two-year clinical trial of oral alendronate versus intravenous pamidronate in children with osteogenesis imperfectaLinda A DiMeglio
Department of Pediatrics, Section of Pediatric Endocrinology and Diabetology, Indiana University School of Medicine, Indianapolis, Indiana, USA
J Bone Miner Res 21:132-40. 2006..Children with mild OI had greater responses than severe OI in BMD and growth... - A comparison of oral and intravenous bisphosphonate therapy for children with osteogenesis imperfectaL A Dimeglio
Department of Pediatrics, Section of Pediatric Endocrinology and Diabetology, Indiana University School of Medicine, Indianapolis, IN, USA
J Pediatr Endocrinol Metab 18:43-53. 2005..All children had a decrease in biochemical markers of bone turnover. Linear growth showed a moderate increase above that for age. There was a non-significant decrease in fracture incidence in both groups... - Intravenous pamidronate treatment of children under 36 months of age with osteogenesis imperfectaL A Dimeglio
Department of Pediatrics, Section of Pediatric Endocrinology and Diabetology, Indiana University School of Medicine, Indianapolis, IN, USA
Bone 35:1038-45. 2004..To examine this, we instituted a prospective clinical trial of intravenous bisphosphonate to study safety, feasibility, and efficacy of this therapy... - A randomized, controlled study of insulin pump therapy in diabetic preschoolersLinda A DiMeglio
Pediatric Endocrinology and Diabetology, Indiana University, 702 Barnhill Drive, Indianapolis, IN 46202, USA
J Pediatr 145:380-4. 2004..To compare glycemic control, safety, and parental satisfaction in preschool-aged diabetic children randomized to treatment either with continuous subcutaneous insulin infusion (CSII) or intensive insulin injection therapy... - Preschoolers are not miniature adolescents: a comparison of insulin pump doses in two groups of children with type 1 diabetes mellitusLinda A DiMeglio
Pediatric Endocrinology and Diabetology, Riley Hospital, Indianapolis, IN 46208, USA
J Pediatr Endocrinol Metab 17:865-70. 2004..Recognizing these variations is essential for safe and efficacious use of CSII in preschoolers with DM1... - Difference in bone mass between black and white American children: attributable to body build, sex hormone levels, or bone turnover?Siu L Hui
Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
J Clin Endocrinol Metab 88:642-9. 2003..The residual racial differences in bone mass were not statistically significant... - Brief report: initial testing of scales measuring parent and adolescent Perceptions of Adolescents' Assumption of Diabetes ManagementKathleen M Hanna
Indiana University School of Nursing, 1111 Middle Drive, NU 451, Indianapolis, Indiana 46202, USA
J Pediatr Psychol 32:245-9. 2007..This study tested parallel adolescent and parent versions of the Perceptions of Adolescents' Assumption of Diabetes Management scales... - A randomized prospective study of insulin pump vs. insulin injection therapy in very young children with type 1 diabetes: 12-month glycemic, BMI, and neurocognitive outcomesZeina M Nabhan
Section of Pediatric Endocrinology and Diabetology, Department of Pediatrics, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, IN 46202, USA
Pediatr Diabetes 10:202-8. 2009.... - Conjugated oral versus transdermal estrogen replacement in girls with Turner syndrome: a pilot comparative studyZeina M Nabhan
Section of Pediatric Endocrinology Diabetology, Indiana University School of Medicine, Riley Hospital for Children, 702 Barnhill Drive, Room 5960, Indianapolis, Indiana 46202, USA
J Clin Endocrinol Metab 94:2009-14. 2009..The optimal route of estrogen replacement in Turner syndrome (TS) is unknown... - Bone mineral accrual and low bone mass: a pediatric perspectiveInessa M Gelfand
Department of Pediatrics, Section of Pediatric Endocrinology and Diabetology, Indiana University, School of Medicine, USA
Rev Endocr Metab Disord 6:281-9. 2005 - Parent and adolescent versions of the diabetes-specific parental support for adolescents' autonomy scale: development and initial testingKathleen M Hanna
Family Health Department, Indiana University School of Nursing, Indianapolis, Indiana 46202, USA
J Pediatr Psychol 30:257-71. 2005..To develop and initially test the psychometric properties of parent and adolescent versions of the Diabetes-Specific Parental Support for Adolescents' Autonomy Scale... 
Treatment of X-linked hypophosphatemia with calcitriol and phosphate increases circulating fibroblast growth factor 23 concentrationsErik A Imel
Departments of Internal Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
J Clin Endocrinol Metab 95:1846-50. 2010..Treating XLH with phosphate and calcitriol may further increase FGF23 concentrations, based on in vitro and in vivo models...- Low hemoglobin levels in children with in idiopathic growth hormone deficiencyErica A Eugster
Department of Pediatrics, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis 46202, USA
Endocrine 18:135-6. 2002..Hemoglobin levels were decreased in children with GH deficiency compared with age-corrected norms... - Using a cell phone-based glucose monitoring system for adolescent diabetes managementAaron E Carroll
Children s Health Services Research, Indiana University School of Medicine, Indianapolis, Indiana, USA
Diabetes Educ 37:59-66. 2011..Mobile technology may be useful in addressing several issues in adolescent diabetes management... - Progressive osseous heteroplasia-like heterotopic ossification in a male infant with pseudohypoparathyroidism type Ia: a case reportInessa M Gelfand
Department of Pediatrics, Division of Pediatric Endocrinology and Diabetology, Indiana University School of Medicine, James Whitcomb Riley Hospital for Children, Indianapolis, IN, USA
Bone 40:1425-8. 2007..Our patient has evidence of both severe POH and PHP Ia, apparently due to a de novo mutation in GNAS... - Predictors of glycemic control on insulin pump therapy in children and adolescents with type I diabetesZeina M Nabhan
Section of Pediatric Endocrinology and Diabetology, Department of Pediatrics, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, IN, USA
Diabetes Res Clin Pract 74:217-21. 2006..CONCLUSION: Only younger age and use of more basal rates were predictive of good diabetes control in children using CSII. Decisions regarding which pediatric patients are most appropriate for CSII must continue to be individualized... - Presentation and clinical progression of pseudohypoparathyroidism with multi-hormone resistance and Albright hereditary osteodystrophy: a case seriesInessa M Gelfand
Department of Pediatrics, Division of Pediatric Endocrinology and Diabetology, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana, USA
J Pediatr 149:877-880. 2006..Temporal trends in stimulatory hormone resistance included early thyroid-stimulating hormone elevation and progression from parathyroid hormone elevation to hyperphosphatemia and hypocalcemia... - Craniofacial and acral growth responses in growth hormone-deficient children treated with growth hormoneDavid G Segal
Pediatric Endocrinology, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA
J Pediatr 144:437-43. 2004..CONCLUSION: Growth hormone treatment with conventional doses partially corrects craniofacial deficits and does not adversely affect hand and foot growth but appears to result in excessive head circumference growth... - Genotype-phenotype correlation in inherited severe insulin resistanceNicola Longo
Division of Medical Genetics, Department of Pediatrics, University of Utah, Salt Lake City 84103, USA
Hum Mol Genet 11:1465-75. 2002..These results indicate that mutations in the insulin receptor retaining residual insulin-binding correlate with prolonged survival in our series of patients with extreme insulin resistance... - Massive ischemic intestinal necrosis at the onset of diabetes mellitus with ketoacidosis in a three-year-old girlLinda A DiMeglio
Section of Pediatric Endocrinology and Diabetology, Department of Pediatrics, Indiana University School of Medicine and J.W. Riley Hospital for Children, Indianapolis, IN 46202, USA
J Pediatr Surg 38:1537-9. 2003..The child survived a complicated postoperative course and currently is thriving on a normal diet... - Autoimmune thyroid dysfunction in children with type 1 diabetes mellitus: screening guidelines based on a retrospective analysisKarl Yaz Bilimoria
Department of Pediatrics, Section of Pediatric Endocrinology and Diabetology, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, IN 46202-5225, USA
J Pediatr Endocrinol Metab 16:1111-7. 2003..The positive predictive value (of TPO and TSH) is 90%, with a positive likelihood ratio of 131... - Severe infantile hypercalcemia associated with Williams syndrome successfully treated with intravenously administered pamidronateAndrew P Cagle
Department of Pediatrics, Section of Pediatric Endocrinology and Diabetology, Indiana University School of Medicine, Indianapolis, Indiana, USA
Pediatrics 114:1091-5. 2004..We conclude that WS-associated hypercalcemia can be quite severe and symptomatic and that it can be successfully and safely treated with intravenously administered bisphosphonate in some cases... - Autosomal dominant osteopetrosis: clinical severity and natural history of 94 subjects with a chloride channel 7 gene mutationSteven G Waguespack
Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas M D Anderson Cancer Center, 1400 Holcombe Blvd, Unit 435, Houston, Texas 77030, USA
J Clin Endocrinol Metab 92:771-8. 2007..The clinical manifestations of this disease have not been well characterized since the discovery of the genetic basis of ADO... - Initial management of infants with intersex conditions in a tertiary care center: a cautionary taleErica A Eugster
J Pediatr Endocrinol Metab 19:191-2. 2006
Research Grants
- MENTORED PATIENT ORIENTED RESEARCH CAREER DEVELOPMENT AWLinda DiMeglio; Fiscal Year: 2004..We will characterize the changes effected by oral bisphosphonate therapy and compare them to a regimen of intravenous bisphosphonate therapy in a group of children with OI. ..