Research Topics
Species | Joseph M CroffieSummaryAffiliation: Indiana University Country: USA Publications
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Publications
Assessment of the effectiveness of biofeedback in children with dyssynergic defecation and recalcitrant constipation/encopresis: does home biofeedback improve long-term outcomesJoseph M Croffie
Division of Pediatric Gastroenterology/Hepatology/Nutrition, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana 46202-5225, USA
Clin Pediatr (Phila) 44:63-71. 2005..Biofeedback is beneficial for some children with chronic constipation and dyssynergic defecation. Supplemental home biofeedback does not improve long-term outcomes...
Accuracy and tolerability of the Bravo catheter-free pH capsule in patients between the ages of 4 and 18 yearsJoseph M Croffie
Section of Pediatric Gastroenterology, Hepatology and Nutrition, Indiana University School of Medicine, Indianapolis, IN 46202, USA
J Pediatr Gastroenterol Nutr 45:559-63. 2007..The aim of this study was to determine if the Bravo pH capsule is comparable to the nasally placed pH catheter in terms of pH-metry, safety, and tolerability in children...
Diagnostic testing and management of gastroesophageal reflux disease (GERD) in childrenJ Cabrera
Children s Hospital of Wisconsin, Medical College of Wisconsin, Milwaukee, WI, USA
Minerva Pediatr 64:585-94. 2012..This review describes the currently employed diagnostic tests and the actual management of GERD in children...
Advances and new technologies in adult endoscopy: can they be adapted to pediatrics?Joseph M Croffie
Indiana University School of Medicine, James Whitcomb Riley Hospital for Children, 702 Barnhill Drive, Room ROC 421, Indianapolis, IN 46202 5225, USA
Curr Gastroenterol Rep 9:208-13. 2007..This review focuses on recent advances and new technologies in adult endoscopy and discusses their adaptability to pediatric patients and the limitations to their adaptation...
Constipation in childrenJoseph M Croffie
Indiana University School of Medicine, James Whitcomb Riley Hospital for Children, Indianapolis, Indiana 46202 5225, USA
Indian J Pediatr 73:697-701. 2006..Treatment should include education, evacuation of the rectum with oral or rectal laxatives if an impaction is present, laxatives to ensure soft stools and behavior modification...
White specks in the esophageal mucosa: An endoscopic manifestation of non-reflux eosinophilic esophagitis in childrenJoel R Lim
Division of Pediatric, Gastroenterology/Hepatology/Nutrition, Division of Pediatric Pathology, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana 46202-5225, USA
Gastrointest Endosc 59:835-8. 2004..Eosinophilic esophagitis tends to be severe when white specks are present (> or =15 eosinophils/high power field) and is not associated with pathologic gastroesophageal reflux, as demonstrated by pH probe testing...
Cysteinyl leukotriene levels in esophageal mucosal biopsies of children with eosinophilic inflammation: are they all the same?Sandeep K Gupta
Division of Pediatric Gastroenterology, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis 46202, USA
Am J Gastroenterol 101:1125-8. 2006..Cysteinyl leukotrienes (CysLT) are eosinophil chemoattractants. We studied CysLT levels in esophageal mucosa of children with AEE and controls...
At what age is a suction rectal biopsy less likely to provide adequate tissue for identification of ganglion cells?Joseph M Croffie
Division of Pediatric Gastroenterology, Hepatology and Nutrition, Indiana University School of Medicine, James Whitcomb Riley Hospital for Children, Indianapolis 46202 5225, USA
J Pediatr Gastroenterol Nutr 44:198-202. 2007..The objective of this study was to determine at what age suction rectal biopsy is less likely to provide adequate tissue to detect submucosal ganglion cells in a child being evaluated for Hirschsprung disease...
Exploring potential noninvasive biomarkers in eosinophilic esophagitis in childrenGirish Subbarao
Division of Pediatric Gastroenterology Hepatology Nutrition, Indiana University School of Medicine, Indianapolis, IN 46202, USA
J Pediatr Gastroenterol Nutr 53:651-8. 2011....
Comparison of serological markers of inflammatory bowel disease with clinical diagnosis in childrenSandeep K Gupta
Division of Pediatric Gastroenterology Hepatology Nutrition, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana, USA
Inflamm Bowel Dis 10:240-4. 2004..Our purpose was to study the concordance of serological tests for inflammatory bowel disease with clinical diagnosis established by traditional testing in children...
Comparison of oral prednisone and topical fluticasone in the treatment of eosinophilic esophagitis: a randomized trial in childrenElizabeth T Schaefer
Indiana University School of Medicine, James Whitcomb Riley Hospital for Children, Division of Pediatric Gastroenterology, Indianapolis, Indiana 46202, USA
Clin Gastroenterol Hepatol 6:165-73. 2008..We conducted a prospective randomized trial comparing oral prednisone (P) and swallowed fluticasone (F) for histologic and clinical response...
Impact of sedation and anesthesia on the rectoanal inhibitory reflex in childrenMarian D Pfefferkorn
Indiana University School of Medicine, James Whitcomb Riley Hospital for Children, Indianapolis, Indiana 46202 5225, USA
J Pediatr Gastroenterol Nutr 38:324-7. 2004..The study objective was to determine whether the rectoanal inhibitory reflex (RAIR) can be elicited during limited anorectal manometry (ARM) performed under general anesthesia (GA)...
The role of esophagogastroduodenoscopy in the initial evaluation of childhood inflammatory bowel disease: a 7-year studyBisher A Abdullah
Division of Gastroenterology, James Whitcomb Riley Hospital for Children, Indiana University Medical Center, Indianapolis, USA
J Pediatr Gastroenterol Nutr 35:636-40. 2002..In some cases, granulomas were found solely in the upper gastrointestinal tracts. Based on our data, esophagogastroduodenoscopy with biopsy should be performed in all pediatric patients with suspected inflammatory bowel disease...
Nocturnal acid breakthrough in children with reflux esophagitis taking proton pump inhibitorsMarian D Pfefferkorn
Division of Pediatric Gastroenterology Hepatology Nutrition, Indiana University School of Medicine, James Whitcomb Riley Hospital for Children, 702 Barnhill Drive, Indianapolis, IN 46202, USA
J Pediatr Gastroenterol Nutr 42:160-5. 2006....
Complications after outpatient upper GI endoscopy in children: 30-day follow-upM Samer Ammar
Division of Pediatric Gastroenterology/Hepatology/Nutrition, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
Am J Gastroenterol 98:1508-11. 2003..All other reported complications or adverse events were infrequent. We conclude that UGE under GA is safe and well tolerated in pediatric patients...
Diagnostic yield of duodenal aspirate for G. lamblia and comparison to duodenal mucosal biopsiesSandeep K Gupta
Division of Pediatric Gastroenterology, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana 46202-5225, USA
Dig Dis Sci 48:605-7. 2003..Duodenal aspirates for Giardia may be unnecessary if duodenal mucosal biopsies are obtained for histological examination...
Correlation between number of eosinophils and reflux index on same day esophageal biopsy and 24 hour esophageal pH monitoringSteven J Steiner
Division of Pediatric Gastroenterology/Hepatology/Nutrition, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana 46202-5225, USA
Am J Gastroenterol 99:801-5. 2004..The finding of more than 20 eosinophils/hpf is likely associated with a normal reflux index and a nonacid-related cause of esophagitis...
Circadian variation of gastroesophageal reflux in childrenSteven J Steiner
Department of Pediatrics, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana 46202-5225, USA
Dig Dis Sci 48:1818-22. 2003..76%) occurred in the early morning. Clinicians should target their antireflux therapy to periods of peak gastroesophageal reflux...
Can colonic manometry studies be done on the day of colonic motility catheter placement?Rana F Ammoury
Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Indiana University School of Medicine, Indianapolis, USA
J Pediatr Gastroenterol Nutr 55:278-82. 2012....
Lactase deficiency: not more common in pediatric patients with inflammatory bowel disease than in patients with chronic abdominal painMarian D Pfefferkorn
Division of Pediatric Gastroenterology Hepatology Nutrition, Indiana University School of Medicine, Indiana 46202, USA
J Pediatr Gastroenterol Nutr 35:339-43. 2002..Lactase deficiency is commonly found in adults with inflammatory bowel disease (IBD). Our aim was to determine its prevalence in children with IBD...
Serum levels of alpha1-antitrypsin predict phenotypic expression of the alpha1-antitrypsin geneSteven J Steiner
Division of Pediatric Gastroenterology/Hepatology/Nutrition, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana 46202-5225, USA
Dig Dis Sci 48:1793-6. 2003..We conclude that serum alpha1-AT levels are highly predictive of the PiZZ phenotype. Determination of the serum alpha1-AT level alone should be the initial test when evaluating for alpha1-AT deficiency...
Diagnostic and therapeutic endoscopic retrograde cholangiopancreatography in children: a large series reportChi-Liang Cheng
Division of Gastroenterology/Hepatology, Indiana University Medical Center, Indianapolis, Indiana 46202, USA
J Pediatr Gastroenterol Nutr 41:445-53. 2005..However, ERCP-related pancreatitis is not uncommon, and the risk and benefits should be carefully reviewed before proceeding. Outcome data are necessary and is currently being accumulated at our institution...
Direct measurement of pancreatic enzymes: a comparison of secretagoguesMarian D Pfefferkorn
Division of Pediatric Gastroenterology, Hepatology and Nutrition, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis 46202, USA
Dig Dis Sci 47:2211-6. 2002..262). Patients in all three groups had at least one normal enzyme. Cholecystokinin is useful as a single agent for direct pancreatic enzyme measurements in the absence of commercially available secretin...
Esophageal pH monitoring with the BRAVO capsule: experience in a single tertiary medical centerJose Cabrera
Division of Pediatric Gastroenterology, Hepatology and Nutrition, Indiana University School of Medicine, Indianapolis, IN 46202, USA
J Pediatr Gastroenterol Nutr 53:404-8. 2011..The aim of the present study was to report the global experience with placement, complication rate, and recording of esophageal pH using the BRAVO capsule at our institution...
Pancreatic enzyme elevations in children with diabetic ketoacidosisNadine G Haddad
Department of Pediatrics, Section of Endocrinology and Diabetology, Indiana University School of Medicine, Indianapolis, 46202, USA
J Pediatr 145:122-4. 2004..Pancreatic enzyme elevations, particularly hyperlipasemia, are common but not associated with significant symptomatology. Acute pancreatitis was diagnosed in 2% of children with DKA...
