Tie Chen

Summary

Affiliation: Indiana University
Country: USA

Publications

  1. ncbi request reprint The CGM1a (CEACAM3/CD66d)-mediated phagocytic pathway of Neisseria gonorrhoeae expressing opacity proteins is also the pathway to cell death
    T Chen
    Department of Microbiology, Immunology and Medicine, Walther Oncology Center, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Biol Chem 276:17413-9. 2001
  2. ncbi request reprint Biliary glycoprotein (BGPa, CD66a, CEACAM1) mediates inhibitory signals
    T Chen
    Department of Microbiology and Immunology, Department of Medicine, and Walther Oncology Center, Indiana University School of Medicine, Indianapolis 46202 5120, USA
    J Leukoc Biol 70:335-40. 2001
  3. pmc Neisseria gonorrhoeae kills carcinoembryonic antigen-related cellular adhesion molecule 1 (CD66a)-expressing human B cells and inhibits antibody production
    Milica Pantelic
    Department of Microbiology and Immunology, Division of Infectious Diseases, Walther Oncology Center, Indiana University School of Medicine, MS415E, 635 Barnhill Dr, Indianapolis, Indiana 46202 5120, USA
    Infect Immun 73:4171-9. 2005
  4. ncbi request reprint Retinoic acid treated HL60 cells express CEACAM1 (CD66a) and phagocytose Neisseria gonorrhoeae
    Milica Pantelic
    Department of Microbiology and Immunology, Division of Infectious Diseases, Walther Oncology Center, Indiana University School of Medicine, Indianapolis, IN, USA
    FEMS Immunol Med Microbiol 42:261-6. 2004
  5. ncbi request reprint Neisseria gonorrhoeae enhances infection of dendritic cells by HIV type 1
    Jizhong Zhang
    Department of Microbiology and Immunology, Division of Infectious Diseases, Walther Oncology Center, Walther Oncology Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    J Immunol 174:7995-8002. 2005
  6. ncbi request reprint Requirement of an additional Sam68 domain for inhibition of human immunodeficiency virus type 1 replication by Sam68 dominant negative mutants lacking the nuclear localization signal
    Jizhong Zhang
    Department of Microbiology and Immunology, Indiana University School of Medicine, R2 302, 950 W Walnut St, Indianapolis, IN 46202, United States
    Gene 363:67-76. 2005

Collaborators

Detail Information

Publications6

  1. ncbi request reprint The CGM1a (CEACAM3/CD66d)-mediated phagocytic pathway of Neisseria gonorrhoeae expressing opacity proteins is also the pathway to cell death
    T Chen
    Department of Microbiology, Immunology and Medicine, Walther Oncology Center, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Biol Chem 276:17413-9. 2001
    ..Unexpectedly, the activation of the CGM1a-ITAM phagocytic pathway by Opa+ GC results in induction of cell death...
  2. ncbi request reprint Biliary glycoprotein (BGPa, CD66a, CEACAM1) mediates inhibitory signals
    T Chen
    Department of Microbiology and Immunology, Department of Medicine, and Walther Oncology Center, Indiana University School of Medicine, Indianapolis 46202 5120, USA
    J Leukoc Biol 70:335-40. 2001
    ..The results suggest that SHP-1 and SHP-2 are required for the FcgammaRIIB-BGPa-mediated inhibitory signals...
  3. pmc Neisseria gonorrhoeae kills carcinoembryonic antigen-related cellular adhesion molecule 1 (CD66a)-expressing human B cells and inhibits antibody production
    Milica Pantelic
    Department of Microbiology and Immunology, Division of Infectious Diseases, Walther Oncology Center, Indiana University School of Medicine, MS415E, 635 Barnhill Dr, Indianapolis, Indiana 46202 5120, USA
    Infect Immun 73:4171-9. 2005
    ..Our results suggest that Neisseria gonorrhoeae possesses the ability to suppress antibody production by killing CEACAM1-expressing B cells...
  4. ncbi request reprint Retinoic acid treated HL60 cells express CEACAM1 (CD66a) and phagocytose Neisseria gonorrhoeae
    Milica Pantelic
    Department of Microbiology and Immunology, Division of Infectious Diseases, Walther Oncology Center, Indiana University School of Medicine, Indianapolis, IN, USA
    FEMS Immunol Med Microbiol 42:261-6. 2004
    ..Our results indicate that the level of expression of CEACAM1 in HL60 cells can be regulated by treatment with RA in a differentiation-dependent manner, and that this is important for phagocytosis of OpaI-expressing gonococci or E. coli...
  5. ncbi request reprint Neisseria gonorrhoeae enhances infection of dendritic cells by HIV type 1
    Jizhong Zhang
    Department of Microbiology and Immunology, Division of Infectious Diseases, Walther Oncology Center, Walther Oncology Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    J Immunol 174:7995-8002. 2005
    ..These results provide one potential mechanism through which GC infection increases HIV replication in patients infected with both GC and HIV...
  6. ncbi request reprint Requirement of an additional Sam68 domain for inhibition of human immunodeficiency virus type 1 replication by Sam68 dominant negative mutants lacking the nuclear localization signal
    Jizhong Zhang
    Department of Microbiology and Immunology, Indiana University School of Medicine, R2 302, 950 W Walnut St, Indianapolis, IN 46202, United States
    Gene 363:67-76. 2005
    ....