R L Bell

Summary

Affiliation: Indiana University
Country: USA

Publications

  1. pmc Animal models for medications development targeting alcohol abuse using selectively bred rat lines: neurobiological and pharmacological validity
    Richard L Bell
    Department of Psychiatry, Institute of Psychiatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Pharmacol Biochem Behav 103:119-55. 2012
  2. pmc Introduction to the special issue "Pharmacotherapies for the treatment of alcohol abuse and dependence" and a summary of patents targeting other neurotransmitter systems
    Richard L Bell
    Indiana University School of Medicine, Department of Psychiatry, Indianapolis, IN 46202, USA
    Recent Pat CNS Drug Discov 7:93-112. 2012
  3. pmc Genetical genomic determinants of alcohol consumption in rats and humans
    Boris Tabakoff
    Department of Pharmacology, University of Colorado, Denver, Aurora, CO, USA
    BMC Biol 7:70. 2009
  4. ncbi request reprint The alcohol-preferring P rat and animal models of excessive alcohol drinking
    Richard L Bell
    Department of Psychiatry, Indiana University School of Medicine, USA
    Addict Biol 11:270-88. 2006
  5. ncbi request reprint Protein expression changes in the nucleus accumbens and amygdala of inbred alcohol-preferring rats given either continuous or scheduled access to ethanol
    R L Bell
    Institute of Psychiatric Research and Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Alcohol 40:3-17. 2006
  6. pmc Effects of short deprivation and re-exposure intervals on the ethanol drinking behavior of selectively bred high alcohol-consuming rats
    Richard L Bell
    Department of Psychiatry, Institute of Psychiatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Alcohol 42:407-16. 2008
  7. pmc Autonomic activation associated with ethanol self-administration in adult female P rats
    Richard L Bell
    Institute of Psychiatric Research, Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Pharmacol Biochem Behav 91:223-32. 2008
  8. pmc Gene expression changes in the nucleus accumbens of alcohol-preferring rats following chronic ethanol consumption
    Richard L Bell
    Department of Psychiatry, Indiana University Purdue University at Indianapolis, Indianapolis, IN 46202, USA
    Pharmacol Biochem Behav 94:131-47. 2009
  9. pmc Modeling binge-like ethanol drinking by peri-adolescent and adult P rats
    Richard L Bell
    Department of Psychiatry, Institute of Psychiatric Research, Indiana University School of Medicine, Indianapolis, IN 46202 4887, USA
    Pharmacol Biochem Behav 100:90-7. 2011
  10. ncbi request reprint Daily patterns of ethanol drinking in peri-adolescent and adult alcohol-preferring (P) rats
    Richard L Bell
    Department of Psychiatry, Institute of Psychiatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Pharmacol Biochem Behav 83:35-46. 2006

Collaborators

Detail Information

Publications22

  1. pmc Animal models for medications development targeting alcohol abuse using selectively bred rat lines: neurobiological and pharmacological validity
    Richard L Bell
    Department of Psychiatry, Institute of Psychiatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Pharmacol Biochem Behav 103:119-55. 2012
    ..The paper also presents some current and future directions for developing pharmacological treatments targeting alcohol abuse and dependence...
  2. pmc Introduction to the special issue "Pharmacotherapies for the treatment of alcohol abuse and dependence" and a summary of patents targeting other neurotransmitter systems
    Richard L Bell
    Indiana University School of Medicine, Department of Psychiatry, Indianapolis, IN 46202, USA
    Recent Pat CNS Drug Discov 7:93-112. 2012
    ..Finally, an overview is presented on the use of pharmacogenetics and pharmacogenomics in tailoring treatments for certain subpopulations of alcoholics, which is expected to continue in the future...
  3. pmc Genetical genomic determinants of alcohol consumption in rats and humans
    Boris Tabakoff
    Department of Pharmacology, University of Colorado, Denver, Aurora, CO, USA
    BMC Biol 7:70. 2009
    ....
  4. ncbi request reprint The alcohol-preferring P rat and animal models of excessive alcohol drinking
    Richard L Bell
    Department of Psychiatry, Indiana University School of Medicine, USA
    Addict Biol 11:270-88. 2006
    ....
  5. ncbi request reprint Protein expression changes in the nucleus accumbens and amygdala of inbred alcohol-preferring rats given either continuous or scheduled access to ethanol
    R L Bell
    Institute of Psychiatric Research and Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Alcohol 40:3-17. 2006
    ..This may reflect differences in neuroanatomical and/or functional characteristics associated with EtOH self-administration and possibly withdrawal, between these two brain structures...
  6. pmc Effects of short deprivation and re-exposure intervals on the ethanol drinking behavior of selectively bred high alcohol-consuming rats
    Richard L Bell
    Department of Psychiatry, Institute of Psychiatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Alcohol 42:407-16. 2008
    ..These findings suggest that (a) an ADE may be observed with short ethanol deprivation and re-exposure intervals in HAD rats, and (b) the genetic make-up of the P and HAD rats influences the expression of this ADE...
  7. pmc Autonomic activation associated with ethanol self-administration in adult female P rats
    Richard L Bell
    Institute of Psychiatric Research, Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Pharmacol Biochem Behav 91:223-32. 2008
    ..Therefore, this behavioral test may prove advantageous in screening pharmacotherapies for reducing craving and relapse, which are associated with cue-reactivity in abstinent alcoholics...
  8. pmc Gene expression changes in the nucleus accumbens of alcohol-preferring rats following chronic ethanol consumption
    Richard L Bell
    Department of Psychiatry, Indiana University Purdue University at Indianapolis, Indianapolis, IN 46202, USA
    Pharmacol Biochem Behav 94:131-47. 2009
    ..Conversely, chronic MSA drinking, with its associated protracted withdrawal periods, results in genomic changes that may be masked by tight regulation of these genes following repeated experiences of ethanol withdrawal...
  9. pmc Modeling binge-like ethanol drinking by peri-adolescent and adult P rats
    Richard L Bell
    Department of Psychiatry, Institute of Psychiatric Research, Indiana University School of Medicine, Indianapolis, IN 46202 4887, USA
    Pharmacol Biochem Behav 100:90-7. 2011
    ..naïve controls) only during the 4th week. Overall, these findings support the use of the DID-MSA procedure in rats, and underscore the presence of age- and sex-dependent effects mediating ethanol binge-like drinking in P rats...
  10. ncbi request reprint Daily patterns of ethanol drinking in peri-adolescent and adult alcohol-preferring (P) rats
    Richard L Bell
    Department of Psychiatry, Institute of Psychiatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Pharmacol Biochem Behav 83:35-46. 2006
    ..This suggests that the effectiveness of treatments for reducing excessive alcohol intake may vary depending upon the age and/or sex of the subjects being tested...
  11. ncbi request reprint Effects of long-term episodic access to ethanol on the expression of an alcohol deprivation effect in low alcohol-consuming rats
    Richard L Bell
    Indiana University School of Medicine, Department of Psychiatry, Institute of Psychiatric Research, 791 Union Drive, Indianapolis, IN 46202 4887, USA
    Alcohol Clin Exp Res 28:1867-74. 2004
    ..In addition, both P and HAD rats display an alcohol deprivation effect (ADE). This study was undertaken to test whether the NP, LAD-1, and LAD-2 lines of rats could display an ADE as well...
  12. ncbi request reprint Effects of concurrent access to a single concentration or multiple concentrations of ethanol on ethanol intake by periadolescent high-alcohol-drinking rats
    Richard L Bell
    Department of Psychiatry, Institute of Psychiatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Alcohol 33:107-15. 2004
    ....
  13. ncbi request reprint Tolerance and morphine-induced cross-tolerance are not shown to Tyr-W-MIF-1 analgesia
    R L Bell
    Department of Psychology, University of New Orleans, LA 70148, USA
    Peptides 20:971-8. 1999
    ..Therefore, tolerance and morphine-induced cross-tolerance were not expressed to Tyr-W-MIF-1 analgesia...
  14. ncbi request reprint Effects of concurrent access to a single concentration or multiple concentrations of ethanol on the intake of ethanol by male and female periadolescent alcohol-preferring (P) rats
    Richard L Bell
    Department of Psychiatry, Indiana University School of Medicine, Indianapolis 46202, USA
    Alcohol 29:137-48. 2003
    ..These findings suggest to us that innate genetically influenced mechanisms promoting high ethanol intake are present at this stage of development...
  15. ncbi request reprint Amphetamine-modified acoustic startle responding and prepulse inhibition in adult and adolescent alcohol-preferring and -nonpreferring rats
    R L Bell
    Institute of Psychiatric Research, Indiana University School of Medicine, 791 Union Drive, Indianapolis, IN 46202 4887, USA
    Pharmacol Biochem Behav 75:163-71. 2003
    ....
  16. ncbi request reprint Heart rate and motor-activating effects of orally self-administered ethanol in alcohol-preferring (P) rats
    Richard L Bell
    Department of Psychiatry, Institute of Psychiatric Research, Indiana University School of Medicine, 791 Union Drive, Indianapolis, IN 46202 4887, USA
    Alcohol Clin Exp Res 26:1162-70. 2002
    ..This study examined changes in heart rate (HR) and motor activity before and during limited-access to ethanol, saccharin, or water in adult male alcohol-preferring (P) rats...
  17. ncbi request reprint Tyr-W-MIF-1-induced conditioned place preference
    W L Nores
    Department of Psychology, University of New Orleans, LA 70148, USA
    Peptides 20:479-84. 1999
    ..Morphine-induced CPP was not affected by Tyr-W-MIF-1 at these doses. These findings show that in the CPP test Tyr-W-MIF-1 produced opiate agonistic effects at the high dose and was without opiate antagonistic properties at lower doses...
  18. ncbi request reprint Low-dose stimulatory effects of ethanol during adolescence in rat lines selectively bred for high alcohol intake
    Z A Rodd
    Department of Psychiatry and Institute of Psychiatric Research, Indiana University School of Medicine, Indianapolis, Indiana 46202 4887, USA
    Alcohol Clin Exp Res 28:535-43. 2004
    ....
  19. ncbi request reprint Effects of concurrent access to multiple ethanol concentrations and repeated deprivations on alcohol intake of alcohol-preferring rats
    Z A Rodd-Henricks
    Department of Psychiatry, Indiana University School of Medicine and Veterans Assistance Medical Center, Indianapolis, Indiana 46202 4887, USA
    Alcohol Clin Exp Res 25:1140-50. 2001
    ..This study examined the effects of initial deprivation length, concurrent exposure to multiple ethanol concentrations, and number of deprivation exposures on the magnitude and duration of the ADE in alcohol-preferring (P) rats...
  20. ncbi request reprint Responsivity and development of tolerance to the motor impairing effects of moderate doses of ethanol in alcohol-preferring (P) and -nonpreferring (NP) rat lines
    R L Bell
    Department of Psychiatry, Institute of Psychiatric Research, Indiana University School of Medicine, Indianapolis 46202-4887, USA
    Alcohol Clin Exp Res 25:644-50. 2001
    ..The present results confirm past research supporting an association between ethanol preference and low ethanol responsivity but at doses that are more reflective of those self-administered by P rats...
  21. pmc The role of 5-HT3 receptors in drug abuse and as a target for pharmacotherapy
    E A Engleman
    Indiana University School of Medicine, Department of Psychiatry, Institute of Psychiatric Research, 791 Union Drive, Indianapolis, IN 46202, USA
    CNS Neurol Disord Drug Targets 7:454-67. 2008
    ....
  22. ncbi request reprint Chest tube removal: end-inspiration or end-expiration?
    R L Bell
    Department of Surgery, Yale University School of Medicine, New Haven, Connecticut, USA
    J Trauma 50:674-7. 2001
    ..A secondary objective was to identify potential risk factors for developing recurrence...