Sunanda Basu

Summary

Affiliation: Indiana University
Country: USA

Publications

  1. pmc CCR5 ligands modulate CXCL12-induced chemotaxis, adhesion, and Akt phosphorylation of human cord blood CD34+ cells
    Sunanda Basu
    Department of Microbiology and Immunology and Walther Oncology Center, Indiana University School of Medicine, Research Institute No 2 Building, Room 302, 950 West Walnut Street, Indianapolis, IN 46202, USA
    J Immunol 183:7478-88. 2009
  2. doi request reprint Mice lacking both G-CSF and IL-6 are more susceptible to Candida albicans infection: critical role of neutrophils in defense against Candida albicans
    Sunanda Basu
    Ludwig Institute for Cancer Research, Melbourne Tumor Biology Branch, Royal Melbourne Hospital, Melbourne, Vic, Australia
    Growth Factors 26:23-34. 2008
  3. ncbi request reprint Candida albicans can stimulate stromal cells resulting in enhanced granulopoiesis
    Sunanda Basu
    Ludwig Institute for Cancer Research, Melbourne Tumor Biology Branch, Royal Melbourne Hospital, Victoria, Australia
    Stem Cells Dev 13:39-50. 2004
  4. pmc Transforming growth factor-{beta}1 modulates responses of CD34+ cord blood cells to stromal cell-derived factor-1/CXCL12
    Sunanda Basu
    Department of Microbiology and Immunology, Walther Oncology Center, Indiana University School of Medicine, Research Institute No 2 Bldg, Rm 302, 950 W Walnut St, Indianapolis, IN 46202 5181, USA
    Blood 106:485-93. 2005
  5. ncbi request reprint Protein phosphatase 2A plays an important role in stromal cell-derived factor-1/CXC chemokine ligand 12-mediated migration and adhesion of CD34+ cells
    Sunanda Basu
    Department of Microbiology and Immunology, Indiana University School of Medicine, 950 West Walnut Street, Indianapolis, IN 46202, USA
    J Immunol 179:3075-85. 2007
  6. ncbi request reprint PP2A in the regulation of cell motility and invasion
    Sunanda Basu
    Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis 46202 5181, USA
    Curr Protein Pept Sci 12:3-11. 2011
  7. ncbi request reprint Macrophage-colony stimulating factor is required for the production of neutrophil-promoting activity by mouse embryo fibroblasts deficient in G-CSF and GM-CSF
    Hui Hua Zhang
    Ludwig Institute for Cancer Research, Melbourne Tumor Biology Branch, Melbourne, Victoria, Australia
    J Leukoc Biol 82:915-25. 2007
  8. ncbi request reprint Evaluation of role of G-CSF in the production, survival, and release of neutrophils from bone marrow into circulation
    Sunanda Basu
    Molecular Biology Laboratory, Ludwig Institute for Cancer Research, Royal Melbourne Hospital, Victoria, Australia
    Blood 100:854-61. 2002
  9. pmc A naturally occurring splice variant of CXCL12/stromal cell-derived factor 1 is a potent human immunodeficiency virus type 1 inhibitor with weak chemotaxis and cell survival activities
    Jeffrey D Altenburg
    Department of Microbiology and Immunology, Indiana University School of Medicine, 635 Barnhill Drive, Room 420, Indianapolis, IN 46202, USA
    J Virol 81:8140-8. 2007
  10. pmc Influence of ERK activation on decreased chemotaxis of mature human cord blood monocyte-derived dendritic cells to CCL19 and CXCL12
    Geling Li
    Department of Microbiology and Immunology, Walther Oncology Center, Indiana University School of Medicine, 950 West Walnut Street, Indianapolis, IN 46202, USA
    Blood 109:3173-6. 2007

Collaborators

Detail Information

Publications14

  1. pmc CCR5 ligands modulate CXCL12-induced chemotaxis, adhesion, and Akt phosphorylation of human cord blood CD34+ cells
    Sunanda Basu
    Department of Microbiology and Immunology and Walther Oncology Center, Indiana University School of Medicine, Research Institute No 2 Building, Room 302, 950 West Walnut Street, Indianapolis, IN 46202, USA
    J Immunol 183:7478-88. 2009
    ..Modulation of CXCL12-mediated responses of CD34(+) cells by CCR5 chemokines provides a possible mechanism that underlies movement of HSPCs during inflammation...
  2. doi request reprint Mice lacking both G-CSF and IL-6 are more susceptible to Candida albicans infection: critical role of neutrophils in defense against Candida albicans
    Sunanda Basu
    Ludwig Institute for Cancer Research, Melbourne Tumor Biology Branch, Royal Melbourne Hospital, Melbourne, Vic, Australia
    Growth Factors 26:23-34. 2008
    ..Similarly, nitric oxide production by peritoneal macrophages from G-CSF(- / - )/IL-6(- / - ) mice in response to Candida is comparable to G-CSF(- / - ) mice...
  3. ncbi request reprint Candida albicans can stimulate stromal cells resulting in enhanced granulopoiesis
    Sunanda Basu
    Ludwig Institute for Cancer Research, Melbourne Tumor Biology Branch, Royal Melbourne Hospital, Victoria, Australia
    Stem Cells Dev 13:39-50. 2004
    ..This study demonstrates that stromal cells can be stimulated with HI Candida and gives an insight into Candida mediated granulopoiesis...
  4. pmc Transforming growth factor-{beta}1 modulates responses of CD34+ cord blood cells to stromal cell-derived factor-1/CXCL12
    Sunanda Basu
    Department of Microbiology and Immunology, Walther Oncology Center, Indiana University School of Medicine, Research Institute No 2 Bldg, Rm 302, 950 W Walnut St, Indianapolis, IN 46202 5181, USA
    Blood 106:485-93. 2005
    ..Our results indicate that low levels of TGF-beta1 can modulate SDF-1 responsiveness of CD34+ cells and thus may facilitate SDF-1-mediated retention and nurturing of stem/progenitor cells in bone marrow...
  5. ncbi request reprint Protein phosphatase 2A plays an important role in stromal cell-derived factor-1/CXC chemokine ligand 12-mediated migration and adhesion of CD34+ cells
    Sunanda Basu
    Department of Microbiology and Immunology, Indiana University School of Medicine, 950 West Walnut Street, Indianapolis, IN 46202, USA
    J Immunol 179:3075-85. 2007
    ..CD34(+) CB cells pretreated with OA showed impaired ability to repopulate NOD-SCID mice in vivo, suggesting physiological relevance of these observations...
  6. ncbi request reprint PP2A in the regulation of cell motility and invasion
    Sunanda Basu
    Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis 46202 5181, USA
    Curr Protein Pept Sci 12:3-11. 2011
    ..This review focuses on the role of PP2A in regulating motility of normal and transformed cells...
  7. ncbi request reprint Macrophage-colony stimulating factor is required for the production of neutrophil-promoting activity by mouse embryo fibroblasts deficient in G-CSF and GM-CSF
    Hui Hua Zhang
    Ludwig Institute for Cancer Research, Melbourne Tumor Biology Branch, Melbourne, Victoria, Australia
    J Leukoc Biol 82:915-25. 2007
    ..Third, NPA production by G-CSF(-/-)/GM-CSF(-/-)/M-CSF(-/-) fibroblasts is enhanced by supplementing culture medium with M-CSF. Thus, stimulation of c-fms by M-CSF is a prerequisite for the production of NPA...
  8. ncbi request reprint Evaluation of role of G-CSF in the production, survival, and release of neutrophils from bone marrow into circulation
    Sunanda Basu
    Molecular Biology Laboratory, Ludwig Institute for Cancer Research, Royal Melbourne Hospital, Victoria, Australia
    Blood 100:854-61. 2002
    ..Collectively, our data suggest that at steady state, G-CSF is critical for the survival of granulocytic cells; however, it is dispensable for trafficking of granulocytes from bone marrow into circulation...
  9. pmc A naturally occurring splice variant of CXCL12/stromal cell-derived factor 1 is a potent human immunodeficiency virus type 1 inhibitor with weak chemotaxis and cell survival activities
    Jeffrey D Altenburg
    Department of Microbiology and Immunology, Indiana University School of Medicine, 635 Barnhill Drive, Room 420, Indianapolis, IN 46202, USA
    J Virol 81:8140-8. 2007
    ....
  10. pmc Influence of ERK activation on decreased chemotaxis of mature human cord blood monocyte-derived dendritic cells to CCL19 and CXCL12
    Geling Li
    Department of Microbiology and Immunology, Walther Oncology Center, Indiana University School of Medicine, 950 West Walnut Street, Indianapolis, IN 46202, USA
    Blood 109:3173-6. 2007
    ..These findings may have potential relevance to better understanding DC function in CB transplantation...
  11. pmc Mad2 is required for optimal hematopoiesis: Mad2 associates with c-Kit in MO7e cells
    Shigeki Ito
    Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis 46202, USA
    Blood 109:1923-30. 2007
    ..These results suggest that Mad2 is involved in synergistic growth of immature hematopoietic progenitor cells in response to SCF plus GM-CSF, effects that may be mediated via physical association of Mad2 with c-Kit...
  12. pmc Overexpression of Rheb2 enhances mouse hematopoietic progenitor cell growth while impairing stem cell repopulation
    Timothy B Campbell
    Department of Microbiology and Immunology, Indiana University School of Medicine, Walther Oncology Center, Indianapolis, IN 46202 5181, USA
    Blood 114:3392-401. 2009
    ..These results may have value in elucidating mechanisms controlling the balance between proliferation and repopulating ability, a finding of importance in clinical uses of HPCs/HSCs...
  13. pmc Peroxisome proliferator-activated-γ coactivator-1α-mediated mitochondrial biogenesis is important for hematopoietic recovery in response to stress
    Sunanda Basu
    Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana 46202 5181, USA
    Stem Cells Dev 22:1678-92. 2013
    ..Loss of PGC-1α also impairs the long-term repopulating potential of HSCs. Our findings may have therapeutic applications for rapid recovery of blood cells following myeloablation...
  14. ncbi request reprint G-CSF: function and modes of action (Review)
    Sunanda Basu
    Ludwig Institute for Cancer Research, Melbourne Tumor Biology Branch, Parkville, Victoria, Australia
    Int J Mol Med 10:3-10. 2002
    ..This review discusses our current state of knowledge regarding the role of G-CSF in granulopoiesis...