Genomes and Genes


Pei Jin


Affiliation: Incyte Corporation
Country: USA


  1. request reprint
    Jin P, Walther D, Zhang J, Rowe Teeter C, Fu G. Serine 171, a conserved residue in the gamma-aminobutyric acid type A (GABAA) receptor gamma2 subunit, mediates subunit interaction and cell surface localization. J Biol Chem. 2004;279:14179-83 pubmed
    ..Mutation of serine 171 in the gamma2 subunit could therefore result in alteration of the structure of the subunit interaction site, preventing correct subunit assembly. ..
  2. request reprint
    Jin P, Zhang J, Rowe Teeter C, Yang J, Stuve L, Fu G. Cloning and characterization of a GABAA receptor gamma2 subunit variant. J Biol Chem. 2004;279:1408-14 pubmed
    ..Together, our results indicate that Ser171 and Tyr172 in the gamma2 subunit constitute a critical motif. When this motif is disrupted by insertion of the alternative exon, access of the gamma2 subunit to the cell surface is prevented. ..