Pamela M Holland
Affiliation: Immunex Corporation
- Purification, cloning, and characterization of Nek8, a novel NIMA-related kinase, and its candidate substrate Bicd2Pamela M Holland
Immunex Corporation, Seattle, Washington 98101, USA
J Biol Chem 277:16229-40. 2002..Treatment of cells with nocodazole leads to dramatic reorganization of Bicd2, and correlates with Nek8 phosphorylation. This may be indicative of a role for Nek8 and Bicd2 associated with cell cycle independent microtubule dynamics...
- RIP4 regulates epidermal differentiation and cutaneous inflammationRyan B Rountree
Department of Oncology, Amgen, Seattle, Washington, USA
J Invest Dermatol 130:102-12. 2010..These data suggest that RIP4 functions in the epidermis through PKC-specific signaling pathways to regulate differentiation and inflammation...
- Protein kinase C-associated kinase is not required for the development of peripheral B lymphocyte populationsStewart T Moran
Massachusetts General Hospital Cancer Center, Harvard Medical School, Building 149, 13th Street, Charlestown, MA 02129, USA
Mol Immunol 43:1694-9. 2006..Taken together, these data demonstrate that the loss of this RIP-family kinase does not compromise B lymphocyte development and maintenance, but leaves open the possibility that PKK may have a redundant role in these processes...