Research Topics
Genomes and Genes | W C DougallSummaryAffiliation: Immunex Corporation Country: USA Publications
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Publications
RANK is essential for osteoclast and lymph node developmentW C Dougall
Immunex Corporation, Seattle, Washington 98101 USA
Genes Dev 13:2412-24. 1999..These experiments reveal that RANK provides critical signals necessary for lymph node organogenesis and osteoclast differentiation...
The involvement of multiple tumor necrosis factor receptor (TNFR)-associated factors in the signaling mechanisms of receptor activator of NF-kappaB, a member of the TNFR superfamilyL Galibert
Department of Molecular Biology, Immunex Corporation, Seattle, Washington 98101, USA
J Biol Chem 273:34120-7. 1998....
A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell functionD M Anderson
Department of Molecular Biology, Immunex Corporation, Seattle, Washington 98101, USA
Nature 390:175-9. 1997..Thus RANK and RANKL seem to be important regulators of interactions between T cells and dendritic cells...
The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domainM A Degli-Esposti
Department of Biochemistry, Immunex Corporation, Seattle, Washington 98101, USA
Immunity 7:813-20. 1997..Like TRAIL-R1 and TRAIL-R2, this receptor shows widespread tissue expression. The human TRAIL-R4 gene has been mapped to chromosome 8p22-21, clustered with three other TRAIL receptors...
