Genomes and Genes
M A Degli-Esposti
Affiliation: Immunex Corporation
- Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor familyM A Degli-Esposti
Department of Biochemistry and the Department of Molecular Biology, Immunex Corporation, Seattle, Washington 98101, USA
J Exp Med 186:1165-70. 1997..Moreover, unlike TRAIL-R1 and -R2, in a transient overexpression system TRAIL-R3 does not induce apoptosis...
- The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domainM A Degli-Esposti
Department of Biochemistry, Immunex Corporation, Seattle, Washington 98101, USA
Immunity 7:813-20. 1997..Like TRAIL-R1 and TRAIL-R2, this receptor shows widespread tissue expression. The human TRAIL-R4 gene has been mapped to chromosome 8p22-21, clustered with three other TRAIL receptors...
- TRAIL-R2: a novel apoptosis-mediating receptor for TRAILH Walczak
Immunex Corporation, 51 University Street, Seattle, WA 98101, USA
EMBO J 16:5386-97. 1997..The existence of two distinct receptors for the same ligand suggests an unexpected complexity to TRAIL biology, reminiscent of dual receptors for TNF, the canonical member of this family...
- Activation of the lymphotoxin beta receptor by cross-linking induces chemokine production and growth arrest in A375 melanoma cellsM A Degli-Esposti
Department of Biochemistry, Immunex Corporation, Seattle, WA 98101, USA
J Immunol 158:1756-62. 1997..These same activities could be induced by membrane-bound and soluble LT beta and LT alpha LT beta oligomers...
- New major histocompatibility complex genesB Marshall
Department of Clinical Immunology, Royal Perth Hospital, Western Australia
Hum Immunol 38:24-9. 1993..PERB6 was identified by YAC probing of tissue blots, while PERB1 was identified by genomic sequencing...
- m144, a murine cytomegalovirus (MCMV)-encoded major histocompatibility complex class I homologue, confers tumor resistance to natural killer cell-mediated rejectionE Cretney
Cellular Immunity Laboratory, The Austin Research Institute, Melbourne, Victoria, Australia
J Exp Med 190:435-44. 1999....