Kevin L Gunderson

Summary

Affiliation: Illumina Inc
Country: USA

Publications

  1. pmc Decoding randomly ordered DNA arrays
    Kevin L Gunderson
    Illumina, Inc, San Diego, California 92121, USA
    Genome Res 14:870-7. 2004
  2. ncbi request reprint Whole-genome genotyping of haplotype tag single nucleotide polymorphisms
    Kevin L Gunderson
    Illumina, Inc, 9885 Towne Centre Dr, San Diego, CA 92121, USA
    Pharmacogenomics 7:641-8. 2006
  3. ncbi request reprint Whole-genome genotyping
    Kevin L Gunderson
    Illumina Inc, San Diego, California, USA
    Methods Enzymol 410:359-76. 2006
  4. ncbi request reprint Whole genome genotyping technologies on the BeadArray platform
    Frank J Steemers
    Illumina, Inc, San Diego, CA, USA
    Biotechnol J 2:41-9. 2007
  5. pmc Power to detect risk alleles using genome-wide tag SNP panels
    Michael A Eberle
    Illumina, San Diego, California, USA
    PLoS Genet 3:1827-37. 2007
  6. pmc Genome-wide assessment of imprinted expression in human cells
    Lisanne Morcos
    McGill University and Genome Quebec Innovation Centre, 740 Dr Penfield Avenue, Montreal, Quebec, H3A 1A4, Canada
    Genome Biol 12:R25. 2011
  7. pmc Comparison of the Agilent, ROMA/NimbleGen and Illumina platforms for classification of copy number alterations in human breast tumors
    L O Baumbusch
    Department of Genetics, Institute for Cancer Research, Norwegian Radium Hospital, Rikshospitalet University Hospital, 0310 Oslo, Norway
    BMC Genomics 9:379. 2008
  8. ncbi request reprint A genome-wide scalable SNP genotyping assay using microarray technology
    Kevin L Gunderson
    Illumina, Inc, 9885 Towne Centre Dr, San Diego, California 92121, USA
    Nat Genet 37:549-54. 2005
  9. doi request reprint Genome-wide DNA methylation profiling using Infinium® assay
    Marina Bibikova
    Illumina Inc, 9885 Towne Centre Dr, San Diego, CA 92121, USA
    Epigenomics 1:177-200. 2009
  10. pmc High-resolution genomic profiling of chromosomal aberrations using Infinium whole-genome genotyping
    Daniel A Peiffer
    Illumina, Inc, San Diego, California 92121, USA
    Genome Res 16:1136-48. 2006

Research Grants

Collaborators

Detail Information

Publications23

  1. pmc Decoding randomly ordered DNA arrays
    Kevin L Gunderson
    Illumina, Inc, San Diego, California 92121, USA
    Genome Res 14:870-7. 2004
    ..The algorithm can be applied to any spatially fixed collection of objects or molecules that are associated with specific DNA sequences...
  2. ncbi request reprint Whole-genome genotyping of haplotype tag single nucleotide polymorphisms
    Kevin L Gunderson
    Illumina, Inc, 9885 Towne Centre Dr, San Diego, CA 92121, USA
    Pharmacogenomics 7:641-8. 2006
    ....
  3. ncbi request reprint Whole-genome genotyping
    Kevin L Gunderson
    Illumina Inc, San Diego, California, USA
    Methods Enzymol 410:359-76. 2006
    ..This automation process increases assay robustness and throughput greatly while enabling laboratory information management system control of sample tracking...
  4. ncbi request reprint Whole genome genotyping technologies on the BeadArray platform
    Frank J Steemers
    Illumina, Inc, San Diego, CA, USA
    Biotechnol J 2:41-9. 2007
    ....
  5. pmc Power to detect risk alleles using genome-wide tag SNP panels
    Michael A Eberle
    Illumina, San Diego, California, USA
    PLoS Genet 3:1827-37. 2007
    ....
  6. pmc Genome-wide assessment of imprinted expression in human cells
    Lisanne Morcos
    McGill University and Genome Quebec Innovation Centre, 740 Dr Penfield Avenue, Montreal, Quebec, H3A 1A4, Canada
    Genome Biol 12:R25. 2011
    ....
  7. pmc Comparison of the Agilent, ROMA/NimbleGen and Illumina platforms for classification of copy number alterations in human breast tumors
    L O Baumbusch
    Department of Genetics, Institute for Cancer Research, Norwegian Radium Hospital, Rikshospitalet University Hospital, 0310 Oslo, Norway
    BMC Genomics 9:379. 2008
    ..Various platforms, brands and underlying technologies are available, facing the user with many choices regarding platform sensitivity and number, localization, and density distribution of probes...
  8. ncbi request reprint A genome-wide scalable SNP genotyping assay using microarray technology
    Kevin L Gunderson
    Illumina, Inc, 9885 Towne Centre Dr, San Diego, California 92121, USA
    Nat Genet 37:549-54. 2005
    ..As proof of principle, we genotyped several hundred previously characterized SNPs. The conversion rate, call rate and accuracy were comparable to those of high-performance PCR-based genotyping assays...
  9. doi request reprint Genome-wide DNA methylation profiling using Infinium® assay
    Marina Bibikova
    Illumina Inc, 9885 Towne Centre Dr, San Diego, CA 92121, USA
    Epigenomics 1:177-200. 2009
    ....
  10. pmc High-resolution genomic profiling of chromosomal aberrations using Infinium whole-genome genotyping
    Daniel A Peiffer
    Illumina, Inc, San Diego, California 92121, USA
    Genome Res 16:1136-48. 2006
    ..Finally, the two analysis modes are compared and contrasted for their utility in analyzing different types of input gDNA: low input amounts, fragmented gDNA, and Phi29 whole-genome pre-amplified DNA...
  11. ncbi request reprint Whole-genome genotyping with the single-base extension assay
    Frank J Steemers
    Illumina, Inc, 9885 Towne Centre Drive, San Diego, California 92121, USA
    Nat Methods 3:31-3. 2006
    ..We show scalability, throughput and accuracy of the system by resequencing homozygous loci from our 100k Human-1 Genotyping BeadChip...
  12. doi request reprint Design of tag SNP whole genome genotyping arrays
    Daniel A Peiffer
    Illumina, Inc, San Diego, CA, USA
    Methods Mol Biol 529:51-61. 2009
    ....
  13. ncbi request reprint Highly parallel genomic assays
    Jian Bing Fan
    Illumina Inc, 9885 Towne Centre Drive, San Diego, California 92121, USA
    Nat Rev Genet 7:632-44. 2006
    ..In the future, most cancers might be staged by high-resolution molecular profiling rather than by gross cytological analysis. Here, we describe the key developments that enable highly parallel genomic assays...
  14. doi request reprint Whole-genome genotyping on bead arrays
    Kevin L Gunderson
    Illumina, Inc, San Diego, CA, USA
    Methods Mol Biol 529:197-213. 2009
    ..Finally, we give several examples of how this advance in genotyping technology is being applied in whole genome association and copy number studies...
  15. ncbi request reprint Illumina universal bead arrays
    Jian Bing Fan
    Illumina, Inc, San Diego, California, USA
    Methods Enzymol 410:57-73. 2006
    ..This chapter describes the concept of the BeadArray technology, two different Array of Arrays formats, the assay scheme and protocol, the performance of the system, and its use in large-scale genetic, epigenetic, and expression studies...
  16. doi request reprint High density DNA methylation array with single CpG site resolution
    Marina Bibikova
    Illumina, Inc 9885 Towne Centre Drive, San Diego, CA 92121, USA
    Genomics 98:288-95. 2011
    ..Highly comparable DNA methylation profiles were generated by the array and sequencing methods (average R2 of 0.95). The ability to determine genome-wide methylation patterns will rapidly advance methylation research...
  17. ncbi request reprint Illumina, Inc
    Frank J Steemers
    Illumina Inc, 9885 Towne Centre Drive, San Diego, CA 92121, USA
    Pharmacogenomics 6:777-82. 2005
    ..Illumina's goal is to deliver high-performance, high-throughput solutions that enable researchers to expand experimental scale while reducing the cost of large-scale research...
  18. pmc Highly parallel oligonucleotide purification and functionalization using reversible chemistry
    Kerri T York
    Illumina, Inc, Advanced Research Group, San Diego, CA 92121, USA
    Nucleic Acids Res 40:e4. 2012
    ..These pools are prepared in up to ~16% yield and 90-99% purity. Approaches for using this method in other applications are also discussed...
  19. doi request reprint Delineation of the proximal 3q microdeletion syndrome
    Marcia J Simovich
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
    Am J Med Genet A 146:1729-35. 2008
    ..We found that ALCAM and CBLB are the only genes deleted in our patient and based on previously published data, we propose that the CBLB gene is responsible for the craniofacial phenotype in patients with deletions of proximal 3q region...
  20. ncbi request reprint Mosaic tetrasomy 12p with triplication of 12p detected by array-based comparative genomic hybridization of peripheral blood DNA
    Zöe Powis
    Section of Medical and Molecular Genetics, Department of Pediatrics, University of Arizona, Tucson, Arizona, USA
    Am J Med Genet A 143:2910-5. 2007
    ..He was determined to be mosaic for 46,XY,trp(12)(p11.2 --> p13) in cultured skin fibroblasts. His appearance was typical for PKS at 4 months of age...
  21. ncbi request reprint Speech delay and autism spectrum behaviors are frequently associated with duplication of the 7q11.23 Williams-Beuren syndrome region
    Jonathan S Berg
    Department of Molecular and Human Genetics, Baylor College of Medicine and Texas Children s Hospital, Houston, Texas 77030, USA
    Genet Med 9:427-41. 2007
    ..23), including two children who inherited the microduplication from one of their parents, to more fully characterize this emerging microduplication syndrome...
  22. ncbi request reprint Indel arrays: an affordable alternative for genotyping
    Neeraj Salathia
    FAS Center for Systems Biology, Harvard University, Cambridge, MA 02138, USA
    Plant J 51:727-37. 2007
    ..Given the ease of use of shotgun sequencing to generate partial genomic sequences of unsequenced species, this approach is readily transferable to non-model organisms...
  23. ncbi request reprint Characterization of seed-specific benzoyloxyglucosinolate mutations in Arabidopsis thaliana
    Daniel J Kliebenstein
    Department of Plant Sciences, University of California Davis, One Shields Ave, Davis, CA 95616, USA
    Plant J 51:1062-76. 2007
    ..Whereas bzo1 mutations have seed-specific effects on benzoyloxyglucosinolate accumulation, the relative abundance of 3-benzoyloxypropyl- and 4-benzoyloxybutylglucosinolates depends on the maternal genotype...

Research Grants2

  1. Allelic expression monitoring by array-based genotyping
    Kevin Gunderson; Fiscal Year: 2004
    ..The culmination of these efforts will result in the whole genome allelic expression study of matched normal/tumor tissues to identify gene loci involved in tumor development. ..
  2. High resolution DNA copy/LOH measurements on WGG arrays
    Kevin Gunderson; Fiscal Year: 2006
    ..Once fully developed, the assay will be employed to characterize biological tumor/normal sample pairs as well as congenital chromosomal imbalances. ..