Research Topics
| Mark A AnastasioSummaryAffiliation: Illinois Institute of Technology Country: USA Publications
Research Grants
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Detail Information
Publications
Image reconstruction in spherical-wave intensity diffraction tomographyMark A Anastasio
Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, Illinois 60616, USA
J Opt Soc Am A Opt Image Sci Vis 22:2651-61. 2005..An underlying theme is that symmetries in tomographic imaging systems can facilitate solutions for phase-retrieval problems. A preliminary numerical investigation of the developed reconstruction methods is presented...- Region-of-interest imaging in differential phase-contrast tomographyMark A Anastasio
Department of Biomedical Engineering, Medical Imaging Research Center, Illinois Institute of Technology, Chicago 60616, USA
Opt Lett 32:3167-9. 2007..We describe and demonstrate an approach to determining regions of interest within an object from truncated differential projection data... 
Analysis of ideal observer signal detectability in phase-contrast imaging employing linear shift-invariant optical systemsMark A Anastasio
Department of Biomedical Engineering, Medical Imaging Research Center, Illinois Institute of Technology, Chicago, Illinois 60616 3793, USA
J Opt Soc Am A Opt Image Sci Vis 27:2648-59. 2010..We demonstrate that this signal detectability measure can be decomposed into three contributions that have distinct interpretations associated with the imaging physics...- Feasibility of half-data image reconstruction in 3-D reflectivity tomography with a spherical apertureMark A Anastasio
Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, IL 60616, USA
IEEE Trans Med Imaging 24:1100-12. 2005..An iterative reconstruction method is utilized for reconstruction of a simulated 3-D object from noiseless and noisy half-scan and half-time data functions... - Local cone-beam tomography image reconstruction on chordsMark A Anastasio
Department of Biomedical Engineering, Illinois Institute of Technology, Chicago 60616, USA
J Opt Soc Am A Opt Image Sci Vis 24:1569-79. 2007..A computer-simulation study is conducted to demonstrate the algorithms and compare their performance with an existing algorithm... - Half-time image reconstruction in thermoacoustic tomographyMark A Anastasio
Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, IL 60616, USA
IEEE Trans Med Imaging 24:199-210. 2005..Reconstructed images and numerical results produced from simulated and experimental TAT measurement data are employed to demonstrate these effects... - Analytic image reconstruction in local phase-contrast tomographyMark A Anastasio
Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, IL 60616, USA
Phys Med Biol 49:121-44. 2004..These reconstruction algorithms are implemented and numerically investigated to corroborate our theoretical assertions... - Multispectral intensity diffraction tomography: single material objects with variable densitiesMark A Anastasio
Department of Biomedical Engineering, Medical Imaging Research Center, Illinois Institute of Technology, Chicago, Illinois 60616, USA
J Opt Soc Am A Opt Image Sci Vis 26:403-12. 2009..Unlike previous multispectral I-DT methods, the proposed method does not require a nondispersive assumption. A computer-simulation study is presented to demonstrate and corroborate the method... - A preliminary investigation of local tomography for megavoltage CT imagingMark A Anastasio
Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, Illinois 60616, USA
Med Phys 30:2969-80. 2003..We demonstrate that the local tomography algorithm is not adversely affected by projection truncation and can reconstruct accurately the boundaries of low-contrast structures within the region of interest from truncated MV projections... - An improved reconstruction algorithm for 3-D diffraction tomography using spherical-wave sourcesMark A Anastasio
Department of Biomedical Engineering, Pritzker Institute of Biomedical Science and Engineering, Illinois Institute of Technology, 10 W 32nd Street, E1 116, Chicago, IL 60616, USA
IEEE Trans Biomed Eng 50:517-21. 2003..Our algorithm is numerically robust and is much more computationally efficient than the conventional filtered backpropagation algorithm. Our previously developed algorithm for DT using plane-wave sources is contained as a special case... - An extended diffraction-enhanced imaging method for implementing multiple-image radiographyCheng Ying Chou
Department of Biomedical Engineering, Illinois Institute of Technology, 10 West 32nd Street, E1 116, Chicago, IL 60616, USA
Phys Med Biol 52:1923-45. 2007..The extended DEI method can be viewed as an implementation of the recently proposed multiple-image radiography paradigm. Validation studies are conducted by use of computer-simulated and synchrotron measurement data... - A physical model of multiple-image radiographyGocha Khelashvili
Center for Synchrotron Radiation Research and Instrumentation, Department of Biological, Chemical and Physical Sciences, Illinois Institute of Technology, Chicago, IL 60616, USA
Phys Med Biol 51:221-36. 2006..Our analysis also shows that MIR truly separates the effects of absorption, refraction and ultra-small-angle scattering for the case considered. We validate our analytical model using real and simulated imaging data... - Half-scan and single-plane intensity diffraction tomography for phase objectsDaxin Shi
Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, IL 60616, USA
Phys Med Biol 49:2733-52. 2004..We implement numerically the reconstruction algorithms and present reconstructed images to demonstrate their use and to corroborate our theoretical assertions... - Image reconstruction in optoacoustic tomography for dispersive acoustic mediaPatrick J La Riviere
Department of Radiology, University of Chicago, 5841 South Maryland Avenue, Chicago, Illinois 60637, USA
Opt Lett 31:781-3. 2006..The improvement in image fidelity that can be achieved over conventional reconstruction methods is demonstrated by use of computer-simulation studies... - Weighted expectation maximization reconstruction algorithms with application to gated megavoltage tomographyJin Zhang
Department of Biomedical Engineering, Illinois Institute of Technology, 10 West 32nd Street, E1-116, Chicago, IL 60616, USA
Phys Med Biol 50:N299-307. 2005..By use of computer-simulated and clinical gated fan-beam megavoltage projection data, we demonstrate that the proposed weighted EM algorithms effectively mitigate such image artefacts... - A computed tomography implementation of multiple-image radiographyJovan G Brankov
Department of Electrical and Computer Engineering, Illinois Institute of Technology, Chicago, IL 60616, USA
Med Phys 33:278-89. 2006..We also investigate the merit of an iterative reconstruction method for use with future clinical implementations of CT-MIR, which we anticipate would be photon limited... - Statistically principled use of in-line measurements in intensity diffraction tomographyYin Huang
Department of Biomedical Engineering, Illinois Institute of Technology, IL, USA
J Opt Soc Am A Opt Image Sci Vis 24:626-42. 2007..Reconstruction methods are developed that exploit the statistical structure of the in-line measurements to minimize the variance of the estimated Fourier components of the object function... - Numerical investigation of the effects of shear waves in transcranial photoacoustic tomography with a planar geometryRobert W Schoonover
Washington University in St Louis, Department of Biomedical Engineering, St Louis, Missouri, USA
J Biomed Opt 17:061215. 2012..Examples are used to demonstrate the importance of accounting for shear waves in transcranial PAT. Error measures are introduced to quantify the error found when omitting shear waves from the forward model in PAT... - Aberration correction for transcranial photoacoustic tomography of primates employing adjunct image dataChao Huang
Washington University in St Louis, Department of Biomedical Engineering, St Louis, Missouri, USA
J Biomed Opt 17:066016. 2012..The results establish that our reconstruction methodology can effectively compensate for skull-induced acoustic aberrations and improve image fidelity in transcranial PAT... - Photoacoustic computed tomography correcting for heterogeneity and attenuationChao Huang
Washington University in St Louis, Department of Biomedical Engineering, St Louis, Missouri 63130, USA
J Biomed Opt 17:061211. 2012..Experiments with phantom objects are presented to validated our findings... - Adaptation of a clustered lumpy background model for task-based image quality assessment in x-ray phase-contrast mammographyAdam M Zysk
Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, IL 60616, USA
Med Phys 39:906-11. 2012..It has been proposed that numerical observers can be used to approximate the statistical performance of human readers, thus enabling the study of task-based performance over a large parameter-space... - Investigation of discrete imaging models and iterative image reconstruction in differential X-ray phase-contrast tomographyQiaofeng Xu
Department of Biomedical Engineering, Washington University in St Louis, Saint Louis, MO 63103, USA
Opt Express 20:10724-49. 2012..We also investigate the use of one of the models with a modern image reconstruction algorithm for performing few-view image reconstruction of a tissue specimen... - Image reconstruction exploiting object sparsity in boundary-enhanced X-ray phase-contrast tomographyEmil Y Sidky
Department of Radiology, The University of Chicago, Chicago, IL 60637, USA
Opt Express 18:10404-22. 2010..We demonstrate that the algorithms can reconstruct accurate boundary-enhanced images from highly incomplete few-view projection data... - Multiple-image radiographyMiles N Wernick
Department of Electrical and Computer Engineering, Illinois Institute of Technology, Chicago, IL 60616, USA
Phys Med Biol 48:3875-95. 2003..MIR results are shown in the form of planar images of a phantom and a biological specimen. A preliminary demonstration of the use of MIR for computed tomography is also presented... - Investigation of iterative image reconstruction in three-dimensional optoacoustic tomographyKun Wang
Department of Biomedical Engineering, Washington University in St Louis, St Louis, MO 63130, USA
Phys Med Biol 57:5399-423. 2012..These features suggest that the use of advanced image reconstruction algorithms can improve the effectiveness of 3D OAT while reducing the amount of data required for biomedical applications... 
Analyzer-based phase-contrast x-ray imaging of carotid plaque microstructureAlyssa A Appel
Department of Research, Hines VA Hospital, Hines, IL 60616 3793, USA
Am J Surg 204:631-6. 2012..This research investigates multiple image radiography (MIR), an x-ray PC imaging technique, for evaluation of human carotid artery plaques...- Image reconstruction in photoacoustic tomography with variable speed of sound using a higher-order geometrical acoustics approximationDimple Modgil
The University of Chicago, Department of Radiology, 5841 South Maryland Avenue, Chicago, Illinois 60637, USA
J Biomed Opt 15:021308. 2010..We evaluate the effect of higher-order GA approximation on image quality and accuracy... - Iterative image reconstruction for PROPELLER-MRI using the nonuniform fast fourier transformAshish A Tamhane
Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, Illinois 60616, USA
J Magn Reson Imaging 32:211-7. 2010..To investigate an iterative image reconstruction algorithm using the nonuniform fast Fourier transform (NUFFT) for PROPELLER (Periodically Rotated Overlapping ParallEL Lines with Enhanced Reconstruction) MRI... - Image reconstruction in photoacoustic tomography involving layered acoustic mediaRobert W Schoonover
Medical Imaging Research Center, Illinois Institute of Technology, Chicago, Illinois, USA
J Opt Soc Am A Opt Image Sci Vis 28:1114-20. 2011..The reconstruction formula is exact in a mathematical sense and accounts for multiple acoustic reflections between the layers of the medium. Computer-simulation studies are conducted to demonstrate and investigate the proposed method... - Framework for computing the spatial coherence effects of polycapillary x-ray opticsAdam M Zysk
Department of Biomedical Engineering, Medical Imaging Research Center, Illinois Institute of Technology, 3440 South Dearborn Street, Suite 100, Chicago, Illinois 60616, USA
Opt Express 20:3975-82. 2012.... - Compensation of shear waves in photoacoustic tomography with layered acoustic mediaRobert W Schoonover
Department of Biomedical Engineering, Washington University in St Louis, St Louis, Missouri 63130, USA
J Opt Soc Am A Opt Image Sci Vis 28:2091-9. 2011..The measurement aperture is assumed to be planar. Computer simulation studies are conducted to demonstrate and investigate the proposed reconstruction formula... - Feasibility study of complex wavefield retrieval in off-axis acoustic holography employing an acousto-optic sensorGuillermo López Rodríguez
Medical Imaging Research Center, Illinois Institute of Technology, Chicago, IL 60616, United States
Ultrasonics 51:847-52. 2011..The proposed method may circumvent limitations of conventional implementations of acoustic holography and may facilitate the development of acoustic-holography-based biomedical imaging methods... - An imaging model incorporating ultrasonic transducer properties for three-dimensional optoacoustic tomographyKun Wang
Department of Biomedical Engineering, Medical Imaging Research Center, Illinois Institute of Technology, Chicago, IL 60616, USA
IEEE Trans Med Imaging 30:203-14. 2011..We demonstrate that use of the imaging model in an iterative reconstruction method can improve the spatial resolution of the optoacoustic images as compared to those reconstructed assuming point-like ultrasound transducers... - Potential for imaging engineered tissues with X-ray phase contrastAlyssa Appel
Department of Biomedical Engineering and Pritzker Institute of Biomedical Science and Engineering, Illinois Institute of Technology, Chicago, Illinois 60616, USA
Tissue Eng Part B Rev 17:321-30. 2011.... - X-ray imaging of poly(ethylene glycol) hydrogels without contrast agentsEric M Brey
Department of Biomedical Engineering, Illinois Institut e of Technology, Chicago, Illinois 60616, USA
Tissue Eng Part C Methods 16:1597-600. 2010..To our knowledge, this is the first study to show that X-ray phase-contrast imaging techniques can identify and provide detail on hydrogel structure without the addition of contrast agents... - Photoacoustic tomography through a whole adult human skull with a photon recyclerLiming Nie
Washington University, Department of Biomedical Engineering, St Louis, Missouri 63130, USA
J Biomed Opt 17:110506. 2012..Our results indicate that PAT can potentially be applied to in vivo human brain imaging... - Imaging of Poly(α-hydroxy-ester) Scaffolds with X-ray Phase-Contrast Microcomputed TomographyAlyssa A Appel
1 Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, Illinois
Tissue Eng Part C Methods 18:859-65. 2012..These results provide evidence of the significant potential of techniques based on X-ray PC for imaging polymer scaffolds... - k-space undersampling in PROPELLER imagingKonstantinos Arfanakis
Department of Biomedical Engineering, Illinois Institute of Technology, 10 West 32nd Street, E1 116, Chicago, IL 60616, USA
Magn Reson Med 53:675-83. 2005..Finally, undersampling using asymmetric blades and taking advantage of Hermitian symmetries to fill-in the missing data significantly reduced imaging time without causing image artifacts... - Transport of intensity and spectrum for partially coherent fieldsAdam M Zysk
Department of Electrical and Computer Engineering, Medical Imaging Research Center, Illinois Institute of Technology, Chicago, Illinois 60616, USA
Opt Lett 35:2239-41. 2010..The results presented here may be used to estimate the intensity response in a variety of phase-contrast imaging modalities and may form the basis for improved phase-retrieval techniques... - A simple Fourier transform-based reconstruction formula for photoacoustic computed tomography with a circular or spherical measurement geometryKun Wang
Department of Biomedical Engineering, Washington University in St Louis, St Louis, MO 63130, USA
Phys Med Biol 57:N493-9. 2012..It also yields a straightforward numerical implementation that is robust and two orders of magnitude more computationally efficient than filtered backprojection algorithms... - Weighted expectation maximization reconstruction algorithms for thermoacoustic tomographyJin Zhang
IEEE Trans Med Imaging 24:817-20. 2005..Using simulated and experimental TAT measurement data, we demonstrate that suitable choices of weighted EM algorithms can effectively mitigate image artifacts that are attributable to temporal truncation of the TAT data function... - On a limited-view reconstruction problem in diffraction tomographyXiaochuan Pan
IEEE Trans Med Imaging 21:413-6. 2002..Based on this observation, we develop short-scan FBPP algorithms that reconstruct a low-pass filtered scattering object from measurements acquired over the angular range [0, phi(c)], where phi(c) < phimin...
Research Grants
- Phase-Contrast Imaging of Microvascular StuctureMARK ANASTASIO; Fiscal Year: 2006..The successful completion of our proposed research will establish in-line phase-contrast tomography as an effective and important modality for imaging microvascular structure. ..
- Design Studies and Optimization of Phase-Contrast MammographyMark A Anastasio; Fiscal Year: 2010..The images it produces will improve a reader's ability to detect subtle cancer features and it could also dramatically reduce the radiation exposure to the patient. ..
- Development of Thermoacoustic Tomography Brain ImagingMark A Anastasio; Fiscal Year: 2010....
- Local Tomography for Radiation Therapy Tumor ImagingMARK ANASTASIO; Fiscal Year: 2005..By increasing the conformality of the radiation therapy treatment procedure, the chances of survival for cancer patients could be improved while simultaneously minimizing the risk of radiation-induced complications. ..