Miguel Muzzio

Summary

Affiliation: IIT Research Institute
Country: USA

Publications

  1. pmc Determination of resveratrol and its sulfate and glucuronide metabolites in plasma by LC-MS/MS and their pharmacokinetics in dogs
    Miguel Muzzio
    Life Sciences Group, IIT Research Institute, Chicago, IL 60616, USA
    J Pharm Biomed Anal 59:201-8. 2012
  2. pmc Determination and stability of CP-31398 in plasma from experimental animals by LC-MS/MS
    Miguel Muzzio
    Life Sciences Group, IIT Research Institute, Chicago, IL 60616, USA
    J Pharm Biomed Anal 56:809-14. 2011
  3. pmc Subchronic oral toxicity and metabolite profiling of the p53 stabilizing agent, CP-31398, in rats and dogs
    William D Johnson
    Life Sciences Group, IIT Research Institute, 10 West 35th Street, Chicago, IL 60616, USA
    Toxicology 289:141-50. 2011
  4. doi request reprint Toxicologic evaluation of tungsten: 28-day inhalation study of tungsten blue oxide in rats
    Narayanan Rajendran
    Illinois Institute of Technology Research Institute, Chicago, USA
    Inhal Toxicol 24:985-94. 2012
  5. pmc Direct quantitation of glucoraphanin in dog and rat plasma by LC-MS/MS
    Michael J Cwik
    Life Sciences Group, IIT Research Institute, 10 West 35th Street, Chicago, IL 60616, USA
    J Pharm Biomed Anal 52:544-9. 2010

Collaborators

Detail Information

Publications5

  1. pmc Determination of resveratrol and its sulfate and glucuronide metabolites in plasma by LC-MS/MS and their pharmacokinetics in dogs
    Miguel Muzzio
    Life Sciences Group, IIT Research Institute, Chicago, IL 60616, USA
    J Pharm Biomed Anal 59:201-8. 2012
    ..Mean molecular-weight adjusted ratios of resveratrol metabolites to resveratrol for AUC ranged from 1 to 9 for resveratrol glucuronide and from 2 to 11 for resveratrol sulfate...
  2. pmc Determination and stability of CP-31398 in plasma from experimental animals by LC-MS/MS
    Miguel Muzzio
    Life Sciences Group, IIT Research Institute, Chicago, IL 60616, USA
    J Pharm Biomed Anal 56:809-14. 2011
    ..The validated method was applied to preclinical toxicology studies in rats and dogs after oral administration of CP-31398...
  3. pmc Subchronic oral toxicity and metabolite profiling of the p53 stabilizing agent, CP-31398, in rats and dogs
    William D Johnson
    Life Sciences Group, IIT Research Institute, 10 West 35th Street, Chicago, IL 60616, USA
    Toxicology 289:141-50. 2011
    ....
  4. doi request reprint Toxicologic evaluation of tungsten: 28-day inhalation study of tungsten blue oxide in rats
    Narayanan Rajendran
    Illinois Institute of Technology Research Institute, Chicago, USA
    Inhal Toxicol 24:985-94. 2012
    ..Based on the absence of other adverse effects, the increased lung weights and the microscopic findings were interpreted as nonadverse response to exposure and were not considered a specific reaction to TBO...
  5. pmc Direct quantitation of glucoraphanin in dog and rat plasma by LC-MS/MS
    Michael J Cwik
    Life Sciences Group, IIT Research Institute, 10 West 35th Street, Chicago, IL 60616, USA
    J Pharm Biomed Anal 52:544-9. 2010
    ..The method has successfully been applied to the determination of glucoraphanin in dog and rat plasma and should be extendable to other species as well...