Affiliation: Idaho State University
Aldape M, Tao A, Heeney D, McIndoo E, French J, Xu D. Experimental identification and computational characterization of a novel extracellular metalloproteinase produced by Clostridium sordellii. RSC Adv. 2017;7:13928-13938 pubmed publisher
..sordellii infections. Follow-up in vitro and in vivo work is under way to further characterize Mcs1 enzymatic kinetics and its role in C. sordellii pathogenesis. ..
Xu D, Ham A, Tivis R, Caylor M, Tao A, Flynn S, et al
. MSBIS: A Multi-Step Biomedical Informatics Screening Approach for Identifying Medications that Mitigate the Risks of Metoclopramide-Induced Tardive Dyskinesia. EBioMedicine. 2017;26:132-137 pubmed publisher
..Using drug-induced TD as an example, we demonstrated that MSBIS is an efficient in silico tool for unknown drug-drug interaction detection, drug repurposing, and combination therapy design. ..