P Kilgannon

Summary

Affiliation: ICOS Corporation
Country: USA

Publications

  1. ncbi request reprint Mapping of the ICAM-5 (telencephalin) gene, a neuronal member of the ICAM family, to a location between ICAM-1 and ICAM-3 on human chromosome 19p13.2
    P Kilgannon
    ICOS Corporation, Bothell, Washington, 98021, USA
    Genomics 54:328-30. 1998
  2. ncbi request reprint The intercellular adhesion molecule (ICAM) family of proteins. New members and novel functions
    J S Hayflick
    ICOS Corp, Bothell, WA 98021, USA
    Immunol Res 17:313-27. 1998
  3. ncbi request reprint Binding of T lymphocytes to hippocampal neurons through ICAM-5 (telencephalin) and characterization of its interaction with the leukocyte integrin CD11a/CD18
    L Tian
    Department of Biosciences, University of Helskinki, Finland
    Eur J Immunol 30:810-8. 2000
  4. pmc Intercellular adhesion molecule-5 induces dendritic outgrowth by homophilic adhesion
    L Tian
    Department of Biosciences, Division of Biochemistry, Viikinkaari 5, University of Helsinki, Helsinki 00014, Finland
    J Cell Biol 150:243-52. 2000
  5. ncbi request reprint Discovery of inhibitors of cell adhesion molecule expression in human endothelial cells. 1. Selective inhibition of ICAM-1 and E-selectin expression
    A O Stewart
    Abbott Laboratories, Pharmaceutical Products Division, Metabolic Diseases Research, Department 04MJ, Building AP10, 100 Abbott Park Road, Abbott Park, Illinois 60064-3500, USA
    J Med Chem 44:988-1002. 2001

Collaborators

  • J S Hayflick
  • C G Gahmberg
  • Gui Dong Zhu
  • L Tian
  • W M Gallatin
  • A O Stewart
  • K Mori
  • Y Yoshihara
  • W Wisdom
  • M A Staeger
  • A J Kempf-Grote
  • P A Bhatia
  • K Lartey
  • L M Melcher
  • B L Cool
  • I W Gunawardana
  • G F Okasinski
  • M V Patel
  • C M McCarty
  • K C Marsh
  • S A Boyd
  • D L Arendsen
  • L Kifle
  • J Meyer
  • D G Fry
  • S Kaukinen
  • H Nyman
  • L C Andersson
  • H Rauvala
  • O Carpen

Detail Information

Publications5

  1. ncbi request reprint Mapping of the ICAM-5 (telencephalin) gene, a neuronal member of the ICAM family, to a location between ICAM-1 and ICAM-3 on human chromosome 19p13.2
    P Kilgannon
    ICOS Corporation, Bothell, Washington, 98021, USA
    Genomics 54:328-30. 1998
    ..This analysis has confirmed the unique expression pattern of this ICAM in human. In addition, we report the mapping of the human ICAM-5 gene to an 80-kb region on chromosome 19p13.2 that also contains ICAM-1 and ICAM-3...
  2. ncbi request reprint The intercellular adhesion molecule (ICAM) family of proteins. New members and novel functions
    J S Hayflick
    ICOS Corp, Bothell, WA 98021, USA
    Immunol Res 17:313-27. 1998
    ..This information has led to the design of novel therapeutic agents that may prove effective in a variety of disease states...
  3. ncbi request reprint Binding of T lymphocytes to hippocampal neurons through ICAM-5 (telencephalin) and characterization of its interaction with the leukocyte integrin CD11a/CD18
    L Tian
    Department of Biosciences, University of Helskinki, Finland
    Eur J Immunol 30:810-8. 2000
    ..This binding was blocked by monoclonal antibodies against CD11a/CD18 and ICAM-5. Thus ICAM-5 may act as a major adhesion molecule for leukocyte binding to neurons in the central nervous system...
  4. pmc Intercellular adhesion molecule-5 induces dendritic outgrowth by homophilic adhesion
    L Tian
    Department of Biosciences, Division of Biochemistry, Viikinkaari 5, University of Helsinki, Helsinki 00014, Finland
    J Cell Biol 150:243-52. 2000
    ..Thus, ICAM-5 displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes...
  5. ncbi request reprint Discovery of inhibitors of cell adhesion molecule expression in human endothelial cells. 1. Selective inhibition of ICAM-1 and E-selectin expression
    A O Stewart
    Abbott Laboratories, Pharmaceutical Products Division, Metabolic Diseases Research, Department 04MJ, Building AP10, 100 Abbott Park Road, Abbott Park, Illinois 60064-3500, USA
    J Med Chem 44:988-1002. 2001
    ..The relative position of the nitrogen atom in the thienopyridine isomer was shown to be critical for activity, as was a small amide 2-substituent...