B D Ross

Summary

Affiliation: Huntington Medical Research Institutes
Country: USA

Publications

  1. ncbi Fusion of the HSV-1 tegument protein vp22 to cytosine deaminase confers enhanced bystander effect and increased therapeutic benefit
    K C Lee
    Department of Biological Chemistry, The University of Michigan Medical Center, Ann Arbor, 48109, USA
    Gene Ther 13:127-37. 2006
  2. ncbi In vivo detection of (15)N-coupled protons in rat brain by ISIS localization and multiple-quantum editing
    K Kanamori
    Magnetic Resonance Spectroscopy Laboratory, Huntington Medical Research Institutes, 660 South Fair Oaks Avenue, Pasadena, California 91105, USA
    J Magn Reson 139:240-9. 1999
  3. ncbi Developmental changes in choline- and ethanolamine-containing compounds measured with proton-decoupled (31)P MRS in in vivo human brain
    S Bluml
    Huntington Medical Research Institutes, Pasadena, California 91105, USA
    Magn Reson Med 42:643-54. 1999
  4. ncbi Real or imaginary? Human metabolism through nuclear magnetism
    B D Ross
    Clinical Magnetic Resonance Spectroscopy Unit, Huntington Medical Research Institutes, Pasadena, California 91105, USA
    IUBMB Life 50:177-87. 2000
  5. ncbi Magnetic resonance spectroscopy of the human brain
    B Ross
    University of Southern California, Los Angeles, USA
    Anat Rec 265:54-84. 2001
  6. ncbi [1-13C]glucose MRS in chronic hepatic encephalopathy in man
    S Bluml
    Huntington Medical Research Institutes, Pasadena, California 91105, USA
    Magn Reson Med 45:981-93. 2001
  7. ncbi 1-(13)C glucose magnetic resonance spectroscopy of pediatric and adult brain disorders
    S Bluml
    Huntington Medical Research Institutes, 660 South Fair Oaks Blvd, Pasadena, CA 91105, USA
    NMR Biomed 14:19-32. 2001
  8. ncbi Swift Acetate Glial Assay (SAGA): an accelerated human ¹³C MRS brain exam for clinical diagnostic use
    Napapon Sailasuta
    Huntington Medical Research Institutes, Pasadena, CA, United States
    J Magn Reson 207:352-5. 2010
  9. ncbi Direct determination of the N-acetyl-L-aspartate synthesis rate in the human brain by (13)C MRS and [1-(13)C]glucose infusion
    A Moreno
    Huntington Medical Research Institutes, Pasadena, California 91105, USA
    J Neurochem 77:347-50. 2001
  10. ncbi Alternative 1-(13)C glucose infusion protocols for clinical (13)C MRS examinations of the brain
    A Moreno
    Clinical Magnetic Resonance Spectroscopy Unit, Huntington Medical Research Institutes, 660 S. Fair Oaks Avenue, Pasadena, CA 91105, USA
    Magn Reson Med 46:39-48. 2001

Collaborators

  • K Kanamori
  • R Schiffmann
  • Napapon Sailasuta
  • Thao T Tran
  • S Bluml
  • A Moreno
  • A P Lin
  • K C Lee
  • P Bhattacharya
  • C H Nguy
  • A Moreno-Torres
  • F Shic
  • J H Hwang
  • A Lin
  • A Rehemtulla
  • K J Dornfeld
  • B A Moffat
  • S Bullarayasamudram
  • D A Hamstra
  • M S Bhojani
  • W H Perman
  • M Mansson
  • D P Weitekamp
  • K Harris
  • V A Norton
  • K Seymour
  • M Philippart
  • C-H Nguy
  • K J Seymour

Detail Information

Publications18

  1. ncbi Fusion of the HSV-1 tegument protein vp22 to cytosine deaminase confers enhanced bystander effect and increased therapeutic benefit
    K C Lee
    Department of Biological Chemistry, The University of Michigan Medical Center, Ann Arbor, 48109, USA
    Gene Ther 13:127-37. 2006
    ..These results together demonstrated that fusion of vp22 to CD resulted in CD translocation, which in turn amplified conversion of 5-FC to 5-FU in vivo and enhanced the therapeutic benefit of this GDEPT strategy...
  2. ncbi In vivo detection of (15)N-coupled protons in rat brain by ISIS localization and multiple-quantum editing
    K Kanamori
    Magnetic Resonance Spectroscopy Laboratory, Huntington Medical Research Institutes, 660 South Fair Oaks Avenue, Pasadena, California 91105, USA
    J Magn Reson 139:240-9. 1999
    ..The advantages and limitations of this method for in vivo application are compared to those of other localized editing techniques currently in use for non-exchanging protons...
  3. ncbi Developmental changes in choline- and ethanolamine-containing compounds measured with proton-decoupled (31)P MRS in in vivo human brain
    S Bluml
    Huntington Medical Research Institutes, Pasadena, California 91105, USA
    Magn Reson Med 42:643-54. 1999
    ..The new quantitative assay may provide novel insights in determining and monitoring normal and abnormal brain maturation noninvasively. Magn Reson Med 42:643-654, 1999...
  4. ncbi Real or imaginary? Human metabolism through nuclear magnetism
    B D Ross
    Clinical Magnetic Resonance Spectroscopy Unit, Huntington Medical Research Institutes, Pasadena, California 91105, USA
    IUBMB Life 50:177-87. 2000
    ....
  5. ncbi Magnetic resonance spectroscopy of the human brain
    B Ross
    University of Southern California, Los Angeles, USA
    Anat Rec 265:54-84. 2001
    ..Although these methods are currently most frequently encountered in human studies, as well as with transgenic and knockout mouse models, MRS adds a new dimension to anatomic and histopathologic descriptions...
  6. ncbi [1-13C]glucose MRS in chronic hepatic encephalopathy in man
    S Bluml
    Huntington Medical Research Institutes, Pasadena, California 91105, USA
    Magn Reson Med 45:981-93. 2001
    ..1-13C] glucose MRS provides novel insights into disease progression and the pathophysiology of chronic hepatic encephalopathy...
  7. ncbi 1-(13)C glucose magnetic resonance spectroscopy of pediatric and adult brain disorders
    S Bluml
    Huntington Medical Research Institutes, 660 South Fair Oaks Blvd, Pasadena, CA 91105, USA
    NMR Biomed 14:19-32. 2001
    ..In this preliminary survey, we conclude that (13)C MRS in combination with glucose infusion is safe and efficient and provides new insights into the pathophysiology of brain disorders...
  8. ncbi Swift Acetate Glial Assay (SAGA): an accelerated human ¹³C MRS brain exam for clinical diagnostic use
    Napapon Sailasuta
    Huntington Medical Research Institutes, Pasadena, CA, United States
    J Magn Reson 207:352-5. 2010
    ..6 min. Results obtained from the new short method (SAGA) were comparable to those achieved in a conventional, long method and effective for determination of glial metabolic rate in posterior-parietal and frontal brain regions...
  9. ncbi Direct determination of the N-acetyl-L-aspartate synthesis rate in the human brain by (13)C MRS and [1-(13)C]glucose infusion
    A Moreno
    Huntington Medical Research Institutes, Pasadena, California 91105, USA
    J Neurochem 77:347-50. 2001
    ..The (13)C MRS technique provides the means for further determination of abnormal rates of neuronal NAA synthesis among neurological disorders in which low cerebral [NAA] has been identified...
  10. ncbi Alternative 1-(13)C glucose infusion protocols for clinical (13)C MRS examinations of the brain
    A Moreno
    Clinical Magnetic Resonance Spectroscopy Unit, Huntington Medical Research Institutes, 660 S. Fair Oaks Avenue, Pasadena, CA 91105, USA
    Magn Reson Med 46:39-48. 2001
    ..Intravenous infusion of 1-(13)C glucose 0.23 g/kg body weight (low dose) provides equivalent information at one third the cost of previous regimes. Magn Reson Med 46:39-48, 2001...
  11. ncbi 13C enrichment of extracellular neurotransmitter glutamate in rat brain--combined mass spectrometry and NMR studies of neurotransmitter turnover and uptake into glia in vivo
    K Kanamori
    Magnetic Resonance Spectroscopy Laboratory, Huntington Medical Research Institutes, 660 S Fair Oaks, Pasadena, CA 91105, USA
    Cell Mol Biol (Noisy-le-grand) 49:819-36. 2003
    ..4 +/- 0.44 micromol/g/hr. Hence, the observed rate represents a reasonable estimate for the rate of glial uptake of GLU(ECF), a process that is crucial for protecting the brain from GLU excitotoxicity...
  12. ncbi The first in vivo observation of (13)C-(15)N coupling in mammalian brain
    K Kanamori
    Magnetic Resonance Spectroscopy Laboratory, Huntington Medical Research Institutes, 660 South Fair Oaks Avenue, Pasadena, California 91105, USA
    J Magn Reson 153:193-202. 2001
    ....
  13. ncbi Accumulation of methylsulfonylmethane in the human brain: identification by multinuclear magnetic resonance spectroscopy
    A Lin
    MR Spectroscopy Unit, Huntington Medical Research Institutes, 660 South Fair Oaks Avenue, Pasadena, CA 91105, USA
    Toxicol Lett 123:169-77. 2001
    ..No adverse clinical or neurochemical effects were observed. Appearance of MSM in significant concentrations in the human brain indicates ready transfer across the intact blood-brain barrier, of a compound with no known medical benefits...
  14. ncbi Tricarboxylic acid cycle of glia in the in vivo human brain
    S Bluml
    Huntington Medical Research Institutes, Pasadena, California 91105, USA
    NMR Biomed 15:1-5. 2002
    ..The mean rate of acetate oxidation calculated from steady-state 13C enrichment of bicarbonate in fasted normal subjects was 0.13 +/- 0.03 micromol/g/min (n=4), approximately 20% of the total cerebral TCA cycle rate...
  15. ncbi Short-echo time proton MR spectroscopy in the presence of gadolinium
    A P Lin
    Magnetic Resonance Spectroscopy Unit, Huntington Medical Research Institutes, Pasadena, CA 91105, USA
    J Comput Assist Tomogr 25:705-12. 2001
    ..02). CONCLUSION: Proton MRS with TE of 30 ms may safely be used in combined contrast-enhanced MRI/MRS protocols. Further study is required with long-TE MRS because of the prolonged T2 of Cho...
  16. ncbi Membrane phospholipids and high-energy metabolites in childhood ataxia with CNS hypomyelination
    S Bluml
    Magnetic Resonance Spectroscopy Unit, Huntington Medical Research Institutes, Pasadena, CA 91105, USA
    Neurology 61:648-54. 2003
    ..Childhood ataxia with CNS hypomyelination (CACH) is a leukodystrophy with extreme rarefaction of white matter caused by mutations in one of the five subunits of the translation initiation factor 2B (eIF2B)...
  17. ncbi Hyperpolarized MR imaging: neurologic applications of hyperpolarized metabolism
    B D Ross
    Huntington Medical Research Institutes, Pasadena, California, USA
    AJNR Am J Neuroradiol 31:24-33. 2010
    ..Recent developments in clinical (13)C neurospectroscopy encourage us to overcome the remaining barriers to clinical HD-MR imaging...
  18. ncbi Ultra-fast three dimensional imaging of hyperpolarized 13C in vivo
    P Bhattacharya
    MR Spectroscopy Unit, Huntington Medical Research Institutes, 10 Pico Street, Pasadena, CA 91105, USA
    MAGMA 18:245-56. 2005
    ..CONCLUSION: 3D-FIESTA was effective for sub-second in vivo imaging of hyperpolarized 13C reagents produced in a custom-built parahydrogen polarizer. Application to 13C hyperpolarized by parahydrogen is demonstrated in vitro and in vivo...