Lynn M Riddiford

Summary

Affiliation: Howard Hughes Medical Institute
Country: USA

Publications

  1. ncbi request reprint Endocrine insights into the evolution of metamorphosis in insects
    James W Truman
    Department of Zoology, University of Washington, Seattle, Washington 98195 1800, USA
    Annu Rev Entomol 47:467-500. 2002
  2. ncbi request reprint Size assessment and growth control: how adult size is determined in insects
    Christen Kerry Mirth
    Department of Biology, University of Washington, Seattle, WA 98195, USA
    Bioessays 29:344-55. 2007
  3. doi request reprint How does juvenile hormone control insect metamorphosis and reproduction?
    Lynn M Riddiford
    Janelia Farm Research Campus, Howard Hughes Medical Institute, 19700 Helix Drive, Ashburn, VA 20147, USA
    Gen Comp Endocrinol 179:477-84. 2012
  4. pmc Temporal patterns of broad isoform expression during the development of neuronal lineages in Drosophila
    Baohua Zhou
    Department of Biology, University of Washington, Seattle, 98195, USA
    Neural Dev 4:39. 2009
  5. pmc A role for juvenile hormone in the prepupal development of Drosophila melanogaster
    Lynn M Riddiford
    Janelia Farm Research Campus, Howard Hughes Medical Institute, 19700 Helix Drive, Ashburn, VA 20147, USA
    Development 137:1117-26. 2010
  6. doi request reprint Juvenile hormone action: a 2007 perspective
    Lynn M Riddiford
    Janelia Farm Research Campus, Howard Hughes Medical Institute, 19700 Helix Drive, Ashburn, VA 20147, USA
    J Insect Physiol 54:895-901. 2008
  7. pmc The ecdysone receptor controls the post-critical weight switch to nutrition-independent differentiation in Drosophila wing imaginal discs
    Christen K Mirth
    Department of Biology, Box 351800, University of Washington, Seattle, WA 98195, USA
    Development 136:2345-53. 2009
  8. ncbi request reprint The role of the prothoracic gland in determining critical weight for metamorphosis in Drosophila melanogaster
    Christen Mirth
    Department of Biology, Box 351800, University of Washington, Seattle, Washington 98195, USA
    Curr Biol 15:1796-807. 2005
  9. pmc The pupal specifier broad directs progressive morphogenesis in a direct-developing insect
    Deniz F Erezyilmaz
    Department of Biology, University of Washington, Box 351800, Seattle, WA 98195 1800, USA
    Proc Natl Acad Sci U S A 103:6925-30. 2006
  10. ncbi request reprint Developmental expression and hormonal regulation of different isoforms of the transcription factor E75 in the tobacco hornworm Manduca sexta
    Bela Keshan
    Department of Biology, University of Washington, Box 351800, Seattle, WA 98195 1800, USA
    Dev Biol 295:623-32. 2006

Collaborators

  • Yuichiro Suzuki
  • Christen K Mirth
  • JAMES TRUMAN
  • Xiaofeng Zhou
  • Masako Asahina
  • Kiyoshi Hiruma
  • Baohua Zhou
  • Mirka Uhlirova
  • Chieka Minakuchi
  • Deniz F Erezyilmaz
  • Ellen J Ward
  • Bela Keshan
  • Steven G B MacWhinnie
  • Charles A Nelson
  • Cynthia Bayer
  • Motoko Shionoya
  • Jianguang Du
  • Geoffrey E Stilwell
  • Marek Jindra
  • Darren W Williams
  • Janet Altman
  • Hannele Ruohola-Baker
  • Celeste A Berg
  • David T Champlin
  • J Paul Allee
  • Barry J Beaty
  • Shinji Nagata
  • Ken E Olson
  • John Weller
  • Hideki Matsubayashi
  • Hiroshi Kataoka
  • Laurence von Kalm
  • Haiyang Cui
  • Brian D Foy
  • Hisato Kuniyoshi

Detail Information

Publications27

  1. ncbi request reprint Endocrine insights into the evolution of metamorphosis in insects
    James W Truman
    Department of Zoology, University of Washington, Seattle, Washington 98195 1800, USA
    Annu Rev Entomol 47:467-500. 2002
    ..We discuss how complete metamorphosis may have influenced the molecular aspects of both ecdysone and JH signaling...
  2. ncbi request reprint Size assessment and growth control: how adult size is determined in insects
    Christen Kerry Mirth
    Department of Biology, University of Washington, Seattle, WA 98195, USA
    Bioessays 29:344-55. 2007
    ..Thus, the mechanisms that control growth rates converge on those assessing size to ensure that the larvae attain the appropriate size at metamorphosis...
  3. doi request reprint How does juvenile hormone control insect metamorphosis and reproduction?
    Lynn M Riddiford
    Janelia Farm Research Campus, Howard Hughes Medical Institute, 19700 Helix Drive, Ashburn, VA 20147, USA
    Gen Comp Endocrinol 179:477-84. 2012
    ..Critical actions of JH and its receptor in the timing of maturation of the adult optic lobe and of female receptivity in Drosophila are also discussed...
  4. pmc Temporal patterns of broad isoform expression during the development of neuronal lineages in Drosophila
    Baohua Zhou
    Department of Biology, University of Washington, Seattle, 98195, USA
    Neural Dev 4:39. 2009
    ..These latter, 'secondary' neurons show a complex pattern of expression of broad, which encodes a transcription factor usually associated with metamorphosis, where it acts as a key regulator in the transitions from larva and pupa...
  5. pmc A role for juvenile hormone in the prepupal development of Drosophila melanogaster
    Lynn M Riddiford
    Janelia Farm Research Campus, Howard Hughes Medical Institute, 19700 Helix Drive, Ashburn, VA 20147, USA
    Development 137:1117-26. 2010
    ..Thus, the lack of JH and its receptor Met causes a heterochronic shift in the development of the visual system that is likely to result from some cells 'misinterpreting' the ecdysteroid peaks that drive metamorphosis...
  6. doi request reprint Juvenile hormone action: a 2007 perspective
    Lynn M Riddiford
    Janelia Farm Research Campus, Howard Hughes Medical Institute, 19700 Helix Drive, Ashburn, VA 20147, USA
    J Insect Physiol 54:895-901. 2008
    ..This short review highlights the recent papers of the past year that lend new insight into the role of this hormone in the larva and the mechanisms whereby it achieves this role...
  7. pmc The ecdysone receptor controls the post-critical weight switch to nutrition-independent differentiation in Drosophila wing imaginal discs
    Christen K Mirth
    Department of Biology, Box 351800, University of Washington, Seattle, WA 98195, USA
    Development 136:2345-53. 2009
    ..These results suggest that post-critical weight, EcR signaling switches wing discs to a nutrition-independent mode of development via derepression...
  8. ncbi request reprint The role of the prothoracic gland in determining critical weight for metamorphosis in Drosophila melanogaster
    Christen Mirth
    Department of Biology, Box 351800, University of Washington, Seattle, Washington 98195, USA
    Curr Biol 15:1796-807. 2005
    ..We present evidence that in Drosophila, a component of the ring gland, the prothoracic gland (PG), assesses growth to determine when critical weight has been achieved...
  9. pmc The pupal specifier broad directs progressive morphogenesis in a direct-developing insect
    Deniz F Erezyilmaz
    Department of Biology, University of Washington, Box 351800, Seattle, WA 98195 1800, USA
    Proc Natl Acad Sci U S A 103:6925-30. 2006
    ..After this shift in br expression, the progressive changes that occur within the nymphal series in basal insects became compressed to the one short period of morphogenesis seen in the larva-to-pupa transition of holometabolous insects...
  10. ncbi request reprint Developmental expression and hormonal regulation of different isoforms of the transcription factor E75 in the tobacco hornworm Manduca sexta
    Bela Keshan
    Department of Biology, University of Washington, Box 351800, Seattle, WA 98195 1800, USA
    Dev Biol 295:623-32. 2006
    ..Neither E75A nor E75D mRNA was up-regulated by JH alone. Thus, E75C is primarily involved in adult differentiation whereas E75D has roles both during the molt and pupal commitment...
  11. pmc Krüppel homolog 1 (Kr-h1) mediates juvenile hormone action during metamorphosis of Drosophila melanogaster
    Chieka Minakuchi
    Department of Biology, University of Washington, Seattle, WA 98195 1800, USA
    Mech Dev 125:91-105. 2008
    ..We also show for the first time that the JH-mediated maintenance of br expression in this epidermis is patterned and that JH delays the fusion of the imaginal cells and the disappearance of Dpp in the dorsal midline...
  12. ncbi request reprint The role of nutrition in creation of the eye imaginal disc and initiation of metamorphosis in Manduca sexta
    Steven G B MacWhinnie
    Department of Biology, University of Southern Maine, 96 Falmouth Street, Portland, ME 04103 9300, USA
    Dev Biol 285:285-97. 2005
    ..Instead, creation of the late-forming imaginal discs in Manduca appears to be controlled by unidentified endocrine factors whose activation is regulated by the nutritional state of the animal...
  13. ncbi request reprint Differential control of MHR3 promoter activity by isoforms of the ecdysone receptor and inhibitory effects of E75A and MHR3
    Kiyoshi Hiruma
    Department of Biology, University of Washington, Seattle, WA 98195 1800, USA
    Dev Biol 272:510-21. 2004
    ..In addition, E75A, another ecdysone-induced transcription factor, and MHR3 itself suppressed MHR3 promoter activity by binding to the monomeric response element (MRE2). Therefore, MHR3 can be down-regulated both by itself and by E75A...
  14. ncbi request reprint Overexpression of broad: a new insight into its role in the Drosophila prothoracic gland cells
    Xiaofeng Zhou
    Department of Biology, University of Washington, Box 351800, Seattle, WA 98195 1800, USA
    J Exp Biol 207:1151-61. 2004
    ..Overexpression of each of the BR isoforms caused degeneration of the PG cells but on different time courses, indicating that BR is a signal for the degeneration of the PG cells that normally occurs during the pupal-adult transition...
  15. ncbi request reprint E74 exhibits stage-specific hormonal regulation in the epidermis of the tobacco hornworm, manduca sexta
    Geoffrey E Stilwell
    Department of Biology, University of Washington, Box 351800, Seattle, WA 98195 1800, USA
    Dev Biol 258:76-90. 2003
    ..Thus, MsE74B appears to have a similar role at the onset of metamorphosis in Manduca as it does in Drosophila, whereas MsE74A is regulated differently at pupation in Manduca than at pupariation in Drosophila...
  16. ncbi request reprint A novel gene in the takeout gene family is regulated by hormones and nutrients in Manduca larval epidermis
    Jianguang Du
    Department of Biology, 24 Kincaid Hall, University of Washington, Box 351800, Seattle, WA 98195 1800, USA
    Insect Biochem Mol Biol 33:803-14. 2003
    ..The role of Moling may be to stabilize JH in the epidermal cell during the final intermolt when the JH esterase activity increases...
  17. ncbi request reprint Evolution of the Drosophila broad locus: the Manduca sexta broad Z4 isoform has biological activity in Drosophila
    Cynthia Bayer
    Department of Biology, University of Central Florida, Orlando, FL 32816 2368, USA
    Dev Genes Evol 213:471-6. 2003
    ....
  18. pmc Use of Sindbis virus-mediated RNA interference to demonstrate a conserved role of Broad-Complex in insect metamorphosis
    Mirka Uhlirova
    Department of Molecular Biology, University of South Bohemia and Institute of Entomology, The Czech Academy of Sciences, Ceske Budejovice, 37005 Czech Republic
    Proc Natl Acad Sci U S A 100:15607-12. 2003
    ..We also demonstrate that the Sindbis virus is a useful vehicle for silencing of developmental genes in new insect models...
  19. ncbi request reprint Insights into the molecular basis of the hormonal control of molting and metamorphosis from Manduca sexta and Drosophila melanogaster
    Lynn M Riddiford
    Department of Biology, University of Washington, 24 Kincaid Hall, Box 351800, Seattle, WA 98195 1800, USA
    Insect Biochem Mol Biol 33:1327-38. 2003
    ..Premature expression of different Broad isoforms also is shown to cause precocious degeneration of the prothoracic glands as well as to prevent ecdysteroid release during its presence...
  20. ncbi request reprint Broad specifies pupal development and mediates the 'status quo' action of juvenile hormone on the pupal-adult transformation in Drosophila and Manduca
    Xiaofeng Zhou
    Department of Zoology, University of Washington, Box 351800, Seattle, WA 98195 1800, USA
    Development 129:2259-69. 2002
    ..Consequently, the 'status quo' action of JH on the pupal-adult transformation is mediated by the JH-induced re-expression of BR...
  21. ncbi request reprint Heat-inducible transgenic expression in the silkmoth Bombyx mori
    Mirka Uhlirova
    University of South Bohemia, Branisovká 31, České Budějovice 370 05, Czech Republic
    Dev Genes Evol 212:145-51. 2002
    ..Immunostaining of epidermis using anti-BmFtz-F1 antibody showed a clear increase of nuclear signal 90 min after a heat shock...
  22. ncbi request reprint Molecular cloning of the prothoracicotropic hormone from the tobacco hornworm, Manduca sexta
    Motoko Shionoya
    Department of Integrated Biosciences, Graduate School of Frontier Sciences, University of Tokyo, Kashiwanoha 5 1 5, Kashiwa 277 8562, Japan
    Insect Biochem Mol Biol 33:795-801. 2003
    ....
  23. pmc rosy Function is required for juvenile hormone effects in Drosophila melanogaster
    Xiaofeng Zhou
    Department of Biology, University of Washington, Seattle, Washington 98195 1800, USA
    Genetics 178:273-81. 2008
    ....
  24. doi request reprint The role of Broad in the development of Tribolium castaneum: implications for the evolution of the holometabolous insect pupa
    Yuichiro Suzuki
    Department of Biology, University of Washington, Box 351800, Seattle, WA 98195 1800, USA
    Development 135:569-77. 2008
    ..Our findings show that the br isoform functions are broadly conserved within the Holometabola and suggest that evolution of br isoform expression may have played an important role in the evolution of the pupa in holometabolous insects...
  25. ncbi request reprint The control of metamorphosis in the kissing bug
    Lynn M Riddiford
    University of Washington, USA
    J Exp Biol 210:3133-4. 2007
  26. ncbi request reprint The morphostatic actions of juvenile hormone
    James W Truman
    Department of Biology, University of Washington, Seattle, WA 98195, USA
    Insect Biochem Mol Biol 37:761-70. 2007
    ..This suppression of embryonic patterning then results in embryonic fields that remain dormant as long as JH is present. These are the primordia that can transform into imaginal discs once JH disappears in preparation for metamorphosis...
  27. ncbi request reprint Border of Notch activity establishes a boundary between the two dorsal appendage tube cell types
    Ellen J Ward
    Department of Biochemistry, University of Washington, Box 357350, Seattle, WA 98195 7350, USA
    Dev Biol 297:461-70. 2006
    ..Generating a boundary by the Notch pathway might constitute an evolutionarily conserved first step during organ formation in many tissues...