Zengjian Hu

Summary

Affiliation: Howard University
Country: USA

Publications

  1. ncbi request reprint WinDock: structure-based drug discovery on Windows-based PCs
    Zengjian Hu
    Department of Biochemistry and Molecular Biology, Howard University College of Medicine, Washington, District of Columbia 20059, USA
    J Comput Chem 28:2347-51. 2007
  2. pmc Prediction of the interaction of HIV-1 integrase and its dicaffeoylquinic acid inhibitor through molecular modeling approach
    Zengjian Hu
    Department of Biochemistry and Molecular Biology, Howard University College of Medicine, Washington, DC 20059, USA
    Ethn Dis 20:S1-45-9. 2010
  3. pmc Computational investigation of the anti-HIV activity of Chinese medicinal formula Three-Huang Powder
    Jack Z Hu
    Department of Biochemistry and Molecular Biology, Howard University College of Medicine, Washington, DC 20059, USA
    Interdiscip Sci 2:151-6. 2010
  4. pmc Ligand binding and circular permutation modify residue interaction network in DHFR
    Zengjian Hu
    Department of Biochemistry and Molecular Biology, Howard University College of Medicine, Washington, District of Columbia, United States of America
    PLoS Comput Biol 3:e117. 2007
  5. ncbi request reprint Molecular modeling of the three-dimensional structure of dopamine 3 (D3) subtype receptor: discovery of novel and potent D3 ligands through a hybrid pharmacophore- and structure-based database searching approach
    Judith Varady
    Departments of Internal Medicine and Medicinal Chemistry, University of Michigan, 3 316 CCGC Box 0934, 1500 East Medical Center Drive, Ann Arbor, MI 48109 0934, USA
    J Med Chem 46:4377-92. 2003

Collaborators

Detail Information

Publications5

  1. ncbi request reprint WinDock: structure-based drug discovery on Windows-based PCs
    Zengjian Hu
    Department of Biochemistry and Molecular Biology, Howard University College of Medicine, Washington, District of Columbia 20059, USA
    J Comput Chem 28:2347-51. 2007
    ..WinDock is coded in C++...
  2. pmc Prediction of the interaction of HIV-1 integrase and its dicaffeoylquinic acid inhibitor through molecular modeling approach
    Zengjian Hu
    Department of Biochemistry and Molecular Biology, Howard University College of Medicine, Washington, DC 20059, USA
    Ethn Dis 20:S1-45-9. 2010
    ..Our study will be of help to design new pharmaceuticals for the treatment of AIDS...
  3. pmc Computational investigation of the anti-HIV activity of Chinese medicinal formula Three-Huang Powder
    Jack Z Hu
    Department of Biochemistry and Molecular Biology, Howard University College of Medicine, Washington, DC 20059, USA
    Interdiscip Sci 2:151-6. 2010
    ..Our study will be of help to identify the pharmacophores of inhibitors binding to HIV-1 integrase and design new pharmaceuticals for the treatment of AIDS...
  4. pmc Ligand binding and circular permutation modify residue interaction network in DHFR
    Zengjian Hu
    Department of Biochemistry and Molecular Biology, Howard University College of Medicine, Washington, District of Columbia, United States of America
    PLoS Comput Biol 3:e117. 2007
    ..Ligand binding at the active site has profound effects on the network centrality, especially the closeness...
  5. ncbi request reprint Molecular modeling of the three-dimensional structure of dopamine 3 (D3) subtype receptor: discovery of novel and potent D3 ligands through a hybrid pharmacophore- and structure-based database searching approach
    Judith Varady
    Departments of Internal Medicine and Medicinal Chemistry, University of Michigan, 3 316 CCGC Box 0934, 1500 East Medical Center Drive, Ann Arbor, MI 48109 0934, USA
    J Med Chem 46:4377-92. 2003
    ..Furthermore, the employed hybrid approach may be more effective for lead discovery from a large chemical database than either pharmacophore-based or structure-based database screening alone...