Robert L Copeland

Summary

Affiliation: Howard University
Country: USA

Publications

  1. ncbi request reprint Cytotoxicity of 2,3-dichloro-5,8-dimethoxy-1,4-naphthoquinone in androgen-dependent and -independent prostate cancer cell lines
    Robert L Copeland
    Department of Pharmacology, College of Medicine and Cancer Center, Howard University, Washington, DC 20059, USA
    Anticancer Res 27:1537-46. 2007
  2. ncbi request reprint Biological evaluation of 2,3-dichloro-5,8-dimethoxy-1,4-naphthoquinone as an anti-breast cancer agent
    Yasmine M Kanaan
    Department of Pharmacologycer, and Howard University, Washington, DC 20059, USA
    Anticancer Res 29:191-9. 2009
  3. pmc Cytotoxic effects of N-(3-chloro-1,4-dioxo 1,4-dihydro-naphthalen-2-yl)-benzamide on androgen-dependent and -independent prostate cancer cell lines
    Yasmine M Kanaan
    Department of Microbiology, College of Medicine, Howard University, Washington, DC 20059, USA
    Anticancer Res 30:519-27. 2010
  4. ncbi request reprint Antiapoptotic effects of nicotine in its protection against salsolinol-induced cytotoxicity
    Robert L Copeland
    Department of Pharmacology, College of Medicine, Howard University, Washington, DC 20059, USA
    Neurotox Res 12:61-9. 2007
  5. pmc Synthesis and cytotoxic activities of some 2-arylnaphtho[2,3-d]oxazole-4,9-dione derivatives on androgen-dependent (LNCaP) and androgen-independent (PC3) human prostate cancer cell lines
    Yakini Brandy
    Department of Chemistry, Howard University, Washington, DC 20059, USA
    Invest New Drugs 30:1709-14. 2012
  6. ncbi request reprint Combined effects of systemic alcohol and nicotine on dopamine release in the nucleus accumbens shell
    Yousef Tizabi
    Department of Pharmacology, College of Medicine, Howard University, 520 W Street NW, Washington, DC 20059, USA
    Alcohol Alcohol 42:413-6. 2007
  7. ncbi request reprint Effects of combined systemic alcohol and central nicotine administration into ventral tegmental area on dopamine release in the nucleus accumbens
    Yousef Tizabi
    Department of Pharmacology, College of Medicine, Howard University, 520 W Street NW, Washington, DC 20059, USA
    Alcohol Clin Exp Res 26:394-9. 2002
  8. ncbi request reprint Neuroprotective effects of nicotine against salsolinol-induced cytotoxicity: implications for Parkinson's disease
    Robert L Copeland
    Department of Pharmacology and Department of Microbiology, College of Medicine, Howard University, Washington, DC 20059, USA
    Neurotox Res 8:289-93. 2005

Collaborators

  • Oladapo Bakare
  • Y Tizabi
  • Yanfei Zhou
  • Yasmine M Kanaan
  • Yakini Brandy
  • Desta Beyene
  • Solomon Berhe
  • Jharna R Das
  • Samuel R Denmeade
  • Yasmine Kanaan
  • Dolapo Adedeji
  • Claudia Mouamba
  • Innocent Ononiwu
  • Ray J Butcher
  • Vonetta Williams
  • Dwayne A Wright
  • Agnes A Day
  • Douglas F White
  • Hillaire Kenguele
  • Nkechi M Enwerem
  • Vonita Williams

Detail Information

Publications8

  1. ncbi request reprint Cytotoxicity of 2,3-dichloro-5,8-dimethoxy-1,4-naphthoquinone in androgen-dependent and -independent prostate cancer cell lines
    Robert L Copeland
    Department of Pharmacology, College of Medicine and Cancer Center, Howard University, Washington, DC 20059, USA
    Anticancer Res 27:1537-46. 2007
    ..DU-145) human prostate cancer cell lines, and/or a normal bone marrow cell line (HS-5). Moreover, the in vitro activity of this compound on cell cycle regulation and apoptosis was evaluated...
  2. ncbi request reprint Biological evaluation of 2,3-dichloro-5,8-dimethoxy-1,4-naphthoquinone as an anti-breast cancer agent
    Yasmine M Kanaan
    Department of Pharmacologycer, and Howard University, Washington, DC 20059, USA
    Anticancer Res 29:191-9. 2009
    ..Moreover, the in vitro activity of this compound on cell cycle regulation and apoptosis were evaluated...
  3. pmc Cytotoxic effects of N-(3-chloro-1,4-dioxo 1,4-dihydro-naphthalen-2-yl)-benzamide on androgen-dependent and -independent prostate cancer cell lines
    Yasmine M Kanaan
    Department of Microbiology, College of Medicine, Howard University, Washington, DC 20059, USA
    Anticancer Res 30:519-27. 2010
    ..Specifically, the in vitro activity of this compound on cell cycle regulation and apoptosis was evaluated...
  4. ncbi request reprint Antiapoptotic effects of nicotine in its protection against salsolinol-induced cytotoxicity
    Robert L Copeland
    Department of Pharmacology, College of Medicine, Howard University, Washington, DC 20059, USA
    Neurotox Res 12:61-9. 2007
    ..Hence, nicotinic agonists in combination with other antiapoptotic agents may be of substantial benefit in at least a subpopulation of Parkinson patients...
  5. pmc Synthesis and cytotoxic activities of some 2-arylnaphtho[2,3-d]oxazole-4,9-dione derivatives on androgen-dependent (LNCaP) and androgen-independent (PC3) human prostate cancer cell lines
    Yakini Brandy
    Department of Chemistry, Howard University, Washington, DC 20059, USA
    Invest New Drugs 30:1709-14. 2012
    ..The meta-substituted 2-(3-Chloro-phenyl)-naphtho[2,3-d]oxazole-4,9-dione (10) appear to display the best cytotoxicity on both cell lines with an IC(50) of 0.03 μM on LNCaP and 0.08 μM on PC3 after 5 days of exposure...
  6. ncbi request reprint Combined effects of systemic alcohol and nicotine on dopamine release in the nucleus accumbens shell
    Yousef Tizabi
    Department of Pharmacology, College of Medicine, Howard University, 520 W Street NW, Washington, DC 20059, USA
    Alcohol Alcohol 42:413-6. 2007
    ..Moreover, to also investigate whether nicotinic receptors may be mediating these effects of alcohol and nicotine, the effects of mecamylamine, a nicotinic receptor antagonist was also evaluated...
  7. ncbi request reprint Effects of combined systemic alcohol and central nicotine administration into ventral tegmental area on dopamine release in the nucleus accumbens
    Yousef Tizabi
    Department of Pharmacology, College of Medicine, Howard University, 520 W Street NW, Washington, DC 20059, USA
    Alcohol Clin Exp Res 26:394-9. 2002
    ....
  8. ncbi request reprint Neuroprotective effects of nicotine against salsolinol-induced cytotoxicity: implications for Parkinson's disease
    Robert L Copeland
    Department of Pharmacology and Department of Microbiology, College of Medicine, Howard University, Washington, DC 20059, USA
    Neurotox Res 8:289-93. 2005
    ..It is suggested that selective nicotinic agonists may be of therapeutic potential in at least a subpopulation of Parkinsonian patients...