Bart G Borghuis

Summary

Affiliation: Howard Hughes Medical Institute
Country: USA

Publications

  1. pmc Loss of sensitivity in an analog neural circuit
    Bart G Borghuis
    Howard Hughes Medical Institute, Janelia Farm Research Campus, Ashburn, Virginia 20147, USA
    J Neurosci 29:3045-58. 2009
  2. pmc Imaging light responses of targeted neuron populations in the rodent retina
    Bart G Borghuis
    Howard Hughes Medical Institute, Janelia Farm Research Campus, Ashburn, Virginia 20147, USA
    J Neurosci 31:2855-67. 2011
  3. doi request reprint An optimized fluorescent probe for visualizing glutamate neurotransmission
    Jonathan S Marvin
    Howard Hughes Medical Institute HHMI, Janelia Farm Research Campus, Ashburn, Virginia, USA
    Nat Methods 10:162-70. 2013
  4. pmc Optimization of a GCaMP calcium indicator for neural activity imaging
    Jasper Akerboom
    Howard Hughes Medical Institute, Janelia Farm Research Campus, Ashburn, Virginia 20147, USA
    J Neurosci 32:13819-40. 2012
  5. pmc Two-photon imaging of nonlinear glutamate release dynamics at bipolar cell synapses in the mouse retina
    Bart G Borghuis
    Department of Ophthalmology and Visual Science and Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut 06511, USA
    J Neurosci 33:10972-85. 2013
  6. pmc Transsynaptic tracing with vesicular stomatitis virus reveals novel retinal circuitry
    KEVIN T BEIER
    Department of Genetics, Howard Hughes Medical Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Neurosci 33:35-51. 2013
  7. pmc A Cre-dependent GCaMP3 reporter mouse for neuronal imaging in vivo
    Hatim A Zariwala
    Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia 20147, USA
    J Neurosci 32:3131-41. 2012

Collaborators

Detail Information

Publications7

  1. pmc Loss of sensitivity in an analog neural circuit
    Bart G Borghuis
    Howard Hughes Medical Institute, Janelia Farm Research Campus, Ashburn, Virginia 20147, USA
    J Neurosci 29:3045-58. 2009
    ..5-fold) across the second synapse. The total retinal loss approximated the known overall loss, supporting the hypothesis that from stimulus to perception, most loss near threshold is retinal...
  2. pmc Imaging light responses of targeted neuron populations in the rodent retina
    Bart G Borghuis
    Howard Hughes Medical Institute, Janelia Farm Research Campus, Ashburn, Virginia 20147, USA
    J Neurosci 31:2855-67. 2011
    ..GCaMP3 expression had no apparent effect on neuronal function. Imaging at subcellular resolution showed compartment-specific calcium dynamics in multiple identified cell types...
  3. doi request reprint An optimized fluorescent probe for visualizing glutamate neurotransmission
    Jonathan S Marvin
    Howard Hughes Medical Institute HHMI, Janelia Farm Research Campus, Ashburn, Virginia, USA
    Nat Methods 10:162-70. 2013
    ..Finally, in mouse forelimb motor cortex, iGluSnFR expression in layer V pyramidal neurons revealed task-dependent single-spine activity during running...
  4. pmc Optimization of a GCaMP calcium indicator for neural activity imaging
    Jasper Akerboom
    Howard Hughes Medical Institute, Janelia Farm Research Campus, Ashburn, Virginia 20147, USA
    J Neurosci 32:13819-40. 2012
    ..GCaMP5 allows more sensitive detection of neural activity in vivo and may find widespread applications for cellular imaging in general...
  5. pmc Two-photon imaging of nonlinear glutamate release dynamics at bipolar cell synapses in the mouse retina
    Bart G Borghuis
    Department of Ophthalmology and Visual Science and Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut 06511, USA
    J Neurosci 33:10972-85. 2013
    ..By visualizing glutamate release in real time, iGluSnFR provides a powerful tool for characterizing glutamate synapses in intact neural circuits. ..
  6. pmc Transsynaptic tracing with vesicular stomatitis virus reveals novel retinal circuitry
    KEVIN T BEIER
    Department of Genetics, Howard Hughes Medical Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Neurosci 33:35-51. 2013
    ..VSV transsynaptic tracing enables cell type-specific dissection of neural circuitry and can reveal synaptic relationships among neurons that are otherwise obscured due to the complexity and density of neuropil...
  7. pmc A Cre-dependent GCaMP3 reporter mouse for neuronal imaging in vivo
    Hatim A Zariwala
    Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia 20147, USA
    J Neurosci 32:3131-41. 2012
    ..Our results show that the Ai38 reporter mouse provides a flexible method for targeted expression of GCaMP3...