Research Topics
| Timothy WrightSummaryAffiliation: Hospital for Special Surgery Country: USA Publications
Research Grants
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Detail Information
Publications
Polyethylene in knee arthroplasty: what is the future?Timothy M Wright
Hospital for Special Surgery, New York, NY 10021, USA
Clin Orthop Relat Res 440:141-8. 2005..A case can be made for and against these polyethylenes, but early clinical results in hip arthroplasty show significantly improved wear, raising the possibility of also improving wear performance in knee arthroplasties...
Current and novel approaches to treating chondral lesionsTimothy M Wright
Department of Biomechanics, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA
J Bone Joint Surg Am 91:120-5. 2009..The challenge of meeting these requirements is difficult, but new forms of computational models and in vitro tests can aid in establishing performance and in rapidly screening possible solutions...- Observations on retrieved glenoid components from total shoulder arthroplastyShane J Nho
Sports Medicine and Shoulder Service, Department of Orthopedic Surgery, Hospital for Special Surgery, Weill Medical College of Cornell University, New York, New York 10021, USA
J Shoulder Elbow Surg 18:371-8. 2009.... - Remelting of highly cross-linked polyethylene worn under laboratory conditionsAdam M Lazzarini
Biomechanics Laboratory, Hospital for Special Surgery, New York, NY 10021, USA
Clin Orthop Relat Res 465:128-32. 2007..Our experiments represent a severe wear case but demonstrate removal of material from the surface through measurable wear prevents the return of identifiable machining marks despite remelting... - The implications of constraint in lumbar total disc replacementRussel C Huang
Spine Surgery Service, Hospital for Special Surgery, New York, New York, USA
J Spinal Disord Tech 16:412-7. 2003..We hope this discussion will assist clinicians and researchers in the design, selection, and clinical comparison of present and future TDR implants... - Bearing surface design changes affect contact patterns in total knee arthroplastyJocelyn M Cottrell
Biomechanics Laboratory, Hospital for Special Surgery, New York, NY 10021, USA
Clin Orthop Relat Res 464:127-31. 2007..Our observations confirm the considerable impact of small changes in conformity and suggest models predicting contact stresses adequately reflect in vivo performance... - Impingement contributes to backside wear and screw-metallic shell fretting in modular acetabular cupsMordechai Kligman
Laboratory for Biomedical Mechanics and Materials, Hospital for Special Surgery, New York, New York, USA
J Arthroplasty 22:258-64. 2007..Our results suggest that impingement in a modular acetabular component correlated with increased backside wear and screw-metallic shell corrosion and fretting... - Retrieval analysis of failed constrained acetabular linersSteven N Shah
Hip and Knee Service, Hospital for Special Surgery, New York, New York, USA
J Arthroplasty 24:54-7. 2009..No association was found between liner damage and clinical and radiographic variables... - Comparison of conforming and nonconforming retrieved glenoid componentsShane J Nho
Sports Medicine and Shoulder Surgery Service, Hospital for Special Surgery, Weill Medical College of Cornell University, New York, NY, USA
J Shoulder Elbow Surg 17:914-20. 2008..05). Articular conformity contributes to differences observed from retrieved polyethylene glenoid components, which are consistent with differences in performance that may influence loosening... 
Tibial post wear in posterior-stabilized knee replacements is design-dependentBridgette D Furman
Department of Biomechanics, Hospital for Special Surgery, New York, NY 10021, USA
Clin Orthop Relat Res 466:2650-5. 2008..These changes cannot occur in isolation, however, because changes in post placement and design also depend on their relation to the shape and location of the tibial bearing surfaces...- Impingement of acetabular cups in a hip simulator: comparison of highly cross-linked and conventional polyethyleneKeith G Holley
Hospital for Special Surgery, Laboratory for Biomedical Mechanics and Materials, New York, USA
J Arthroplasty 20:77-86. 2005..Wear rates and damage of highly cross-linked polyethylene cups were significantly higher in an impingement wear test than in previous simulator studies... - Mechanisms for pumping fluid through cementless acetabular components with holesWilliam L Walter
Hospital for Special Surgery, New York, New York, USA
J Arthroplasty 20:1042-8. 2005..Pistoning motion of the liner produced pressures 8 times higher than when no pistoning occurs. These pumping mechanisms could be mitigated by the use of acetabular components without holes... - Validation of cartilage thickness calculations using indentation analysisMatthew F Koff
Department of Radiology and Imaging, Hospital for Special Surgery, New York, NY 10021, USA
J Biomech Eng 132:041007. 2010..The accuracy of the measurements was comparable to previous cartilage thickness validation studies in literature. The results of this study will aid in validating a tool for clinical evaluation of in-vivo cartilage thickness... - Use of instrumented pedicle screws to evaluate load sharing in posterior dynamic stabilization systemsKathleen Meyers
Department of Biomechanics, Hospital for Special Surgery, 535 E 70th Street, New York, NY 10021, USA
Spine J 8:926-32. 2008..If the implant system distributes these loads more evenly, loads in the pedicle screws will be reduced, and screw loosening will be prevented... - Observations on retrieved humeral polyethylene components from reverse total shoulder arthroplastyDenis Nam
Sports Medicine and Shoulder Service, Department of Orthopedic Surgery, Hospital for Special Surgery, Weill Medical College of Cornell University, New York, NY 10021, USA
J Shoulder Elbow Surg 19:1003-12. 2010.... - Mechanical performance of ceramic acetabular liners under impact conditionsSuzanne A Maher
Laboratory for Biomedical Mechanics and Materials, Hospital for Special Surgery, New York, New York 10021, USA
J Arthroplasty 18:936-41. 2003..The threshold force of 12 kN is large in comparison with estimated physiologic forces on the hip during falls or stumbling, suggesting that ceramic liner fracture is not a definite consequence of liner impact... - Biomechanics of nonfusion implantsRussel C Huang
Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA
Orthop Clin North Am 36:271-80. 2005..Implant design issues can also markedly affect performance... - Evaluation of a porous polyurethane scaffold in a partial meniscal defect ovine modelSuzanne A Maher
Hospital for Special Surgery, 535 E 70th Street, New York, NY 10021, USA
Arthroscopy 26:1510-9. 2010..The objective of this study was to assess the performance of a degradable porous polyurethane scaffold in a partial meniscectomy ovine model... - Radiographic and histopathologic analysis of osteolysis after total shoulder arthroplastyChristopher K Kepler
Sports Medicine and Shoulder Service, Department of Orthopaedic Surgery, Hospital for Special Surgery, New York, NY 10021, USA
J Shoulder Elbow Surg 19:588-95. 2010..This study analyzed clinical, radiographic, and histologic data from failed total shoulder arthroplasties (TSAs) to determine factors associated with osteolysis... - The mechanical behavior of locking compression plates compared with dynamic compression plates in a cadaver radius modelMichael J Gardner
Department of Orthopaedic Surgery, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA
J Orthop Trauma 19:597-603. 2005.... - Role of parathyroid hormone in the mechanosensitivity of fracture healingMichael J Gardner
Hospital for Special Surgery, 535 East 70th Street, New York, New York 10021, USA
J Orthop Res 25:1474-80. 2007..This finding may be of potential clinical utility when weight bearing is utilized to stimulate lower extremity fracture healing... - Comparison of early and delayed failed total shoulder arthroplastyChristopher K Kepler
Sports Medicine and Shoulder Service, Department of Orthopaedic Surgery, Hospital for Special Surgery, 535 East 70th Street New York, NY 10021, USA
Acta Orthop Belg 75:297-305. 2009..40%). The Delayed group had higher damage scores for several damage modalities. Elderly age and osteoarthritis were significant factors that were associated with early failures after TSA... - High stress conditions do not increase wear of thin highly crosslinked UHMWPENatalie H Kelly
Department of Biomechanics, Hospital for Special Surgery, 535 E 70th Street, New York, NY 10021, USA
Clin Orthop Relat Res 468:418-23. 2010..Continued monitoring will be necessary to elucidate the clinical efficacy of these devices... - In vivo cyclic axial compression affects bone healing in the mouse tibiaMichael J Gardner
Hospital for Special Surgery, New York, New York, USA
J Orthop Res 24:1679-86. 2006..As the loading parameters necessary to enhance fracture healing become refined, external compression may be used as a potent stimulus for treating fractures with decreased biological capacity... - Stair ascent kinematics affect UHMWPE wear and damage in total knee replacementsJocelyn M Cottrell
Laboratory for Biomedical Mechanics and Materials, Hospital for Special Surgery, New York, New York, USA
J Biomed Mater Res B Appl Biomater 78:15-9. 2006..The fact that even small bouts of an additional activity of daily living could markedly impact wear simulator results calls into question the usefulness of studies that rely solely on kinematics and load inputs assumed from level gait... - Biomechanic comparison of the Teno Fix tendon repair device with the cruciate and modified Kessler techniquesScott W Wolfe
Division of Hand and Upper Extremity Surgery, Hospital for Special Surgery, New York, NY, USA
J Hand Surg Am 32:356-66. 2007..To compare the mechanical behavior of a novel internal tendon repair device with commonly used 2-strand and 4-strand repair techniques for zone II flexor tendon lacerations... - Effect of crosslinking, remelting, and aging on UHMWPE damage in a linear experimental wear modelSuzanne A Maher
Department of Biomechanics, Hospital for Special Surgery, 535 East 70th Street, New York, New York 10021, USA
J Orthop Res 25:849-57. 2007..A low dose of irradiation followed by heat treatment has the same beneficial effects in terms of improved wear performance, but without the disadvantages of reduced fracture toughness found with higher doses of irradiation... - A new technique to measure the dynamic contact pressures on the Tibial PlateauJocelyn M Cottrell
Department of Biomechanics, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA
J Biomech 41:2324-9. 2008..It is envisaged that the experimental model herein developed will allow for the screening of candidate materials prior to more expensive and time-consuming animal models... - PFC knee replacement: osteolytic failures from extreme polyethylene degradationDavid Casey
Hospital for Special Surgery, New York, NY 10021, USA
Clin Orthop Relat Res 464:157-63. 2007..However, they raise questions concerning the cellular reaction to the debris from PFC implants that could lead to a better general understanding of osteolysis... - Use of an absorbable membrane to position biologically inductive materials in the periprosthetic space of cemented jointsGene R DiResta
Orthopaedics Research Laboratory, Memorial Sloan Kettering Cancer Center, RRL 409, 430 E67th St, New York, NY 10021, USA
J Biomech 39:833-43. 2006..Aseptic loosening and lameness occurred within 12 months, quicker than the 30 months reported in a retrospective clinical review of canine hip arthroplasty... - Failure at the taper lock of a modular stemmed femoral implant in revision knee arthroplasty. A report of two cases and a retrieval analysisPaul S Issack
Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA
J Bone Joint Surg Am 89:2271-4. 2007 - Impingement in total hip arthroplasty a study of retrieved acetabular componentsWon Yong Shon
Department of Biochemical Mechanics and Materials, Hospital for Special Surgery, New York, NY 10021, USA
J Arthroplasty 20:427-35. 2005..Implant design, in particular head/neck ratio, can help reduce the prevalence of impingement... - An optical method for evaluation of geometric fidelity for anatomically shaped tissue-engineered constructsJeffrey J Ballyns
Department of Biomedical Engineering, Cornell University, Ithaca, New York, USA
Tissue Eng Part C Methods 16:693-703. 2010..This work shows the ability to generate and quantify anatomically shaped meniscal constructs of high geometric fidelity and lends insight into the relative geometric fidelities of several tissue engineering techniques... - Superior versus anteroinferior plating of the clavicle revisited: a mechanical studyGeorge Partal
Orthopaedic Trauma Service, Hospital for Special Surgery, New York, NY 10021, USA
J Orthop Trauma 24:420-5. 2010..This study was designed to compare bone-implant stiffness of two fixation techniques on a sawbone model of a clavicle fracture... - Abnormal mineral-matrix interactions are a significant contributor to fragility in oim/oim boneElizabeth Miller
Musculoskeletal Integrity Program, Research Division, Hospital for Special Surgery, 535 E 70th Street, New York, NY 10021, USA
Calcif Tissue Int 81:206-14. 2007.... - Late fiber metal shedding of the first and second-generation Harris Galante acetabular component. A report of 5 casesDavid J Mayman
Hospital for Special Surgery, Weill Medical College, Cornell University, New York, New York 10021, USA
J Arthroplasty 22:624-9. 2007..Fiber metal separation may contribute to long-term loosening in the Harris Galante acetabular component... - Lack of hormonal influences on mechanical properties of sheep knee ligamentsSabrina M Strickland
Hospital for Special Surgery, New York, New York 10021, USA
Am J Sports Med 31:210-5. 2003..CLINICAL RELEVANCE: The female hormonal milieu may not be responsible for the increased incidence of anterior cruciate ligament injury in female athletes compared with their male counterparts... - Bone mass is preserved and cancellous architecture altered due to cyclic loading of the mouse tibia after orchidectomyJ Christopher Fritton
Field of Biomedical Engineering, Cornell University, Ithaca, New York, USA
J Bone Miner Res 23:663-71. 2008..In this study, we tested the hypothesis that cyclic mechanical loading of the mouse tibia inhibits orchidectomy (ORX)-associated cancellous bone loss... - Biomechanical evaluation of an expandable nail for the fixation of midshaft fracturesSuzanne A Maher
Department of Biomechanics, Hospital for Special Surgery, New York, NY, USA
J Trauma 63:103-7. 2007..The objective of this study was to compare the torsional stability of diaphyseal long bone fractures fixed with either a Fixion nail (DiscOTech, Monroe Township, NJ) or a standard locked Zimmer M/DN locked nail (Zimmer, Warsaw, IN)... - Image-guided tissue engineering of anatomically shaped implants via MRI and micro-CT using injection moldingJeffery J Ballyns
Mechanical and Aerospace Engineering, Cornell University, Ithaca, New York, USA
Tissue Eng Part A 14:1195-202. 2008.... - Late fatigue fracture of a modern cemented [corrected] cobalt chrome stem for total hip arthroplasty: a report of 10 casesAlejandro Gonzalez Della Valle
Hospital for Special Surgery, New York, NY 10021, USA
J Arthroplasty 20:1084-8. 2005..In the presence of a spontaneous onset of thigh pain at intermediate follow-up in patients with this stem, particularly if associated with loss of calcar support, a fatigue fracture should be considered... - A novel surface treatment for porous metallic implants that improves the rate of bony ongrowthFintan J Shannon
Laboratory for Biomedical Mechanics and Materials, Hospital for Special Surgery, 535 East 70th St, New York, New York 10021, USA
J Biomed Mater Res A 86:857-64. 2008..Where early implant fixation is important, the SAMP treatment provides a simple, cost-effective enhancement to bony integration of orthopaedic implants... - Wear simulation of the ProDisc-L disc replacement using adaptive finite element analysisJeremy J Rawlinson
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA
J Neurosurg Spine 7:165-73. 2007..The authors analyzed the wear potential of a ProDisc-L implant using an adaptive finite element (FE) technique in a computational simulation representing a physical wear test... - Retrieval, experimental, and computational assessment of the performance of total knee replacementsJeremy J Rawlinson
Mechanical and Aerospace Engineering, Cornell University, Ithaca, New York 14853, USA
J Orthop Res 24:1384-94. 2006..Combining these techniques strengthens the applicability of the computational simulation while highlighting the complementary approach of these methods for preclinical testing and assessing the link between material state and damage... - Cancellous bone strains indicate efficacy of stem augmentation in constrained condylar kneesJeremy J Rawlinson
Cornell University, Ithaca, NY 14850, USA
Clin Orthop Relat Res 440:107-16. 2005..Therefore, patient selection and proper sizing of the implant were identified as important factors in the analyses... - Pause insertions during cyclic in vivo loading affect bone healingMichael J Gardner
Department of Orthopaedic Surgery, Harborview Medical Center, 325 9th Ave, Box 359798, Seattle, WA 98104, USA
Clin Orthop Relat Res 466:1232-8. 2008..At an early stage of fracture healing, pause-inserted loading led to more histologically advanced healing... - Stemmed implants improve stability in augmented constrained condylar kneesJeremy J Rawlinson
Cornell University, Ithaca, NY, USA
Clin Orthop Relat Res 466:2639-43. 2008..The wedge carried more axial load compared to the primary implant due to its support on stiff metaphyseal bone... - The CXC chemokine murine monokine induced by IFN-gamma (CXC chemokine ligand 9) is made by APCs, targets lymphocytes including activated B cells, and supports antibody responses to a bacterial pathogen in vivoMatthew K Park
Inflammation Biology Section, Laboratory of Clinical Investigation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
J Immunol 169:1433-43. 2002....
Research Grants
- Knee Implant Wear Evaluation-An Integrated ApproachTimothy Wright; Fiscal Year: 2005..abstract_text> ..
- Improving the performance of elbow reconstructionTimothy M Wright; Fiscal Year: 2010..Our goal is to explain the locations and mechanisms of failure, thereby suggesting solutions to improve the efficacy of this treatment. ..