H S Sandhu

Summary

Affiliation: Hospital for Special Surgery
Country: USA

Publications

  1. ncbi request reprint Recombinant human bone morphogenetic protein-2: use in spinal fusion applications
    Harvinder S Sandhu
    Spinal Surgery Service, The Hospital for Special Surgery, New York, NY 10021, USA
    J Bone Joint Surg Am 85:89-95. 2003
  2. ncbi request reprint Bone morphogenetic proteins and spinal surgery
    Harvinder S Sandhu
    Department of Orthopaedic Surgery, Hospital for Special Surgery, Weill Cornell Medical College, New York, New York 10021, USA
    Spine (Phila Pa 1976) 28:S64-73. 2003
  3. pmc Demineralized bone matrix, bone morphogenetic proteins, and animal models of spine fusion: an overview
    H S Sandhu
    Spinal Surgical Service, Hospital for Special Surgery, Weill Medical College of Cornell University, New York, NY 10021, USA
    Eur Spine J 10:S122-31. 2001
  4. ncbi request reprint Association between findings of provocative discography and vertebral endplate signal changes as seen on MRI
    H S Sandhu
    Department of Orthopaedic Surgery, Hospital for Special Surgery, Weill Medical College of Cornell University, New York, New York 10021, USA
    J Spinal Disord 13:438-43. 2000
  5. ncbi request reprint Experimental spinal fusion with recombinant human bone morphogenetic protein-2 without decortication of osseous elements
    H S Sandhu
    Department of Orthopaedic Surgery, UCLA School of Medicine, USA
    Spine (Phila Pa 1976) 22:1171-80. 1997
  6. ncbi request reprint Effective doses of recombinant human bone morphogenetic protein-2 in experimental spinal fusion
    H S Sandhu
    Department of Orthopaedic Surgery, UCLA School of Medicine, USA
    Spine (Phila Pa 1976) 21:2115-22. 1996
  7. ncbi request reprint Evaluation of rhBMP-2 with an OPLA carrier in a canine posterolateral (transverse process) spinal fusion model
    H S Sandhu
    Department of Orthopaedic Surgery, UCLA School of Medicine, USA
    Spine (Phila Pa 1976) 20:2669-82. 1995
  8. ncbi request reprint The use of rhBMP-2 in interbody fusion cages. Definitive evidence of osteoinduction in humans: a preliminary report
    S D Boden
    Department of Orthopaedic Surgery, Emory University School of Medicine, Atlanta, Georgia, USA
    Spine (Phila Pa 1976) 25:376-81. 2000
  9. ncbi request reprint Metal debris from titanium spinal implants
    J C Wang
    Department of Orthopaedic Surgery, School of Medicine, University of California, Los Angeles, USA
    Spine (Phila Pa 1976) 24:899-903. 1999
  10. ncbi request reprint Incidental durotomy in spine surgery
    F P Cammisa
    SpineCare Institute, Hospital for Special Surgery, New York, New York 10021, USA
    Spine (Phila Pa 1976) 25:2663-7. 2000

Collaborators

Detail Information

Publications35

  1. ncbi request reprint Recombinant human bone morphogenetic protein-2: use in spinal fusion applications
    Harvinder S Sandhu
    Spinal Surgery Service, The Hospital for Special Surgery, New York, NY 10021, USA
    J Bone Joint Surg Am 85:89-95. 2003
  2. ncbi request reprint Bone morphogenetic proteins and spinal surgery
    Harvinder S Sandhu
    Department of Orthopaedic Surgery, Hospital for Special Surgery, Weill Cornell Medical College, New York, New York 10021, USA
    Spine (Phila Pa 1976) 28:S64-73. 2003
    ..A review of the literature concerning the use of recombinant human bone morphogenetic proteins 2 (rhBMP-2) and 7 (rhBMP-7) in spinal fusion...
  3. pmc Demineralized bone matrix, bone morphogenetic proteins, and animal models of spine fusion: an overview
    H S Sandhu
    Spinal Surgical Service, Hospital for Special Surgery, Weill Medical College of Cornell University, New York, NY 10021, USA
    Eur Spine J 10:S122-31. 2001
    ..Finally, exciting new gene therapy research is discussed, with comments made on its applicability for the future...
  4. ncbi request reprint Association between findings of provocative discography and vertebral endplate signal changes as seen on MRI
    H S Sandhu
    Department of Orthopaedic Surgery, Hospital for Special Surgery, Weill Medical College of Cornell University, New York, New York 10021, USA
    J Spinal Disord 13:438-43. 2000
    ..7%, respectively, for levels with no patient pain on discography). Our data showed no significant relationship between these distinct diagnostic tools. Further investigation of their relative roles in this application is recommended...
  5. ncbi request reprint Experimental spinal fusion with recombinant human bone morphogenetic protein-2 without decortication of osseous elements
    H S Sandhu
    Department of Orthopaedic Surgery, UCLA School of Medicine, USA
    Spine (Phila Pa 1976) 22:1171-80. 1997
    ..With higher doses of recombinant human bone morphoganetic protein-2, there was little histologic distinction between fusions in decorticated versus undecorticated spines...
  6. ncbi request reprint Effective doses of recombinant human bone morphogenetic protein-2 in experimental spinal fusion
    H S Sandhu
    Department of Orthopaedic Surgery, UCLA School of Medicine, USA
    Spine (Phila Pa 1976) 21:2115-22. 1996
    ..CONCLUSIONS: No mechanical, radiographic, or histologic differences in the quality of intertransverse process fusion resulted from a 40-fold variation in dose of recombinant human bone morphogenetic protein-2...
  7. ncbi request reprint Evaluation of rhBMP-2 with an OPLA carrier in a canine posterolateral (transverse process) spinal fusion model
    H S Sandhu
    Department of Orthopaedic Surgery, UCLA School of Medicine, USA
    Spine (Phila Pa 1976) 20:2669-82. 1995
    ..Spontaneous transverse process fusion does not occur in canines after decortication and open-cell polylactic acid polymer implantation...
  8. ncbi request reprint The use of rhBMP-2 in interbody fusion cages. Definitive evidence of osteoinduction in humans: a preliminary report
    S D Boden
    Department of Orthopaedic Surgery, Emory University School of Medicine, Atlanta, Georgia, USA
    Spine (Phila Pa 1976) 25:376-81. 2000
    ..A prospective randomized controlled human clinical pilot trial...
  9. ncbi request reprint Metal debris from titanium spinal implants
    J C Wang
    Department of Orthopaedic Surgery, School of Medicine, University of California, Los Angeles, USA
    Spine (Phila Pa 1976) 24:899-903. 1999
    ..A prospective study of tissue surrounding spinal instrumentation was performed using histologic and chemical analysis...
  10. ncbi request reprint Incidental durotomy in spine surgery
    F P Cammisa
    SpineCare Institute, Hospital for Special Surgery, New York, New York 10021, USA
    Spine (Phila Pa 1976) 25:2663-7. 2000
    ..Retrospective review of a large series of patients who underwent spinal surgery at a single institution during a 10-year period...
  11. ncbi request reprint Correlation between vertebral body rotation and two-dimensional vertebral bone density measurement
    F P Girardi
    SpineCare Institute, Hospital for Special Surgery, New York, NY 10021, USA
    Osteoporos Int 12:738-40. 2001
    ..The measurement change may be as high as 20%. This fact should be considered when investigating scoliotic patients with vertebral segment rotation...
  12. ncbi request reprint Sudden sensorineural hearing loss after spinal surgery under general anesthesia
    F P Girardi
    SpineCare Institute, Hospital for Special Surgery, New York, New York 10021, USA
    J Spinal Disord 14:180-3. 2001
    ..We encourage the continued reporting of sudden sensorineural hearing loss after spinal surgery...
  13. ncbi request reprint Predictors of functional outcome in elderly patients undergoing posterior lumbar spine surgery
    F Zheng
    Spine Service, Hospital for Special Surgery, New York, New York 10021, USA
    J Spinal Disord 14:518-21. 2001
    ..05). The modified low back outcome score questionnaire system is a reliable method in elderly patients...
  14. ncbi request reprint A comparison of magnetic resonance and computed tomographic image quality after the implantation of tantalum and titanium spinal instrumentation
    J C Wang
    Department of Orthopaedic Surgery, University of California, Los Angeles Center for Health Sciences, USA
    Spine (Phila Pa 1976) 23:1684-8. 1998
    ..However, computed tomographic scanning is not the imaging modality of choice for the tantalum spinal implants because of the large amounts of artifact...
  15. ncbi request reprint Distractive properties of a threaded interbody fusion device. An in vivo model
    H S Sandhu
    Department of Orthopaedic Surgery, UCLA School of Medicine, USA
    Spine (Phila Pa 1976) 21:1201-10. 1996
    ..CONCLUSION. Despite early subsidence, interbody fusion cages successfully distracted and preserved interbody spaces. This model is useful for investigating methods of improving distraction and stabilization...
  16. ncbi request reprint Outcome of revision discectomies following recurrent lumbar disc herniation
    Elias C Papadopoulos
    Hospital for Special Surgery, New York, NY 10021, USA
    Spine (Phila Pa 1976) 31:1473-6. 2006
    ..Retrospective study...
  17. ncbi request reprint Influence of rhBMP-2 on the healing patterns associated with allograft interbody constructs in comparison with autograft
    J Kenneth Burkus
    Wilderness Spine Services, Hughston Clinic, Columbus, GA 31909, USA
    Spine (Phila Pa 1976) 31:775-81. 2006
    ..A prospective, nonblinded, multicenter study...
  18. ncbi request reprint Alendronate inhibits spine fusion in a rat model
    Russel C Huang
    Hospital for Special Surgery, New York, New York 10021, USA
    Spine (Phila Pa 1976) 30:2516-22. 2005
    ..A posterolateral lumbar fusion model in rats...
  19. ncbi request reprint Use of rhBMP-2 in combination with structural cortical allografts: clinical and radiographic outcomes in anterior lumbar spinal surgery
    J Kenneth Burkus
    Wilderness Spine Services, The Hughston Clinic, 6262 Veterans Parkway, Columbus, GA 31909, USA
    J Bone Joint Surg Am 87:1205-12. 2005
    ..However, a larger series with longer follow-up is needed to demonstrate its superiority to autogenous iliac crest bone graft...
  20. ncbi request reprint Cervical epidural abscess after epidural steroid injection
    Russel C Huang
    Department of Orthopaedic Surgery, Hospital for Special Surgery, New York, NY, USA
    Spine (Phila Pa 1976) 29:E7-9. 2004
    ..This is a case report of a cervical epidural abscess presenting with neurologic deficits after cervical epidural steroid injection...
  21. ncbi request reprint A cost analysis of bone morphogenetic protein versus autogenous iliac crest bone graft in single-level anterior lumbar fusion
    David W Polly
    Orthopedic Surgery Service, Walter Reed Army Medical Center, Washington, DC 20307 5001, USA
    Orthopedics 26:1027-37. 2003
    ....
  22. ncbi request reprint Discordantly high spinal bone mineral density values in patients with adult lumbar scoliosis
    Ioannis P Pappou
    Hospital for Special Surgery, New York, NY 10021, USA
    Spine (Phila Pa 1976) 31:1614-20. 2006
    ..Retrospective study...
  23. ncbi request reprint BMPs and gene therapy for spinal fusion: summary statement
    Harvinder S Sandhu
    Spine (Phila Pa 1976) 28:S85. 2003
    ..Gene therapy technologies are in the preclinical stage of development. In time, biologic interventions will continue to capture greater roles in the treatment of spinal disease...
  24. ncbi request reprint Histologic evaluation of the efficacy of rhBMP-2 compared with autograft bone in sheep spinal anterior interbody fusion
    Harvinder S Sandhu
    Department of Orthopaedic Surgery and UCLA Comprehensive Spine Center, UCLA School of Medicine, Los Angeles, California, USA
    Spine (Phila Pa 1976) 27:567-75. 2002
    ..Comparisons were drawn from temporal radiographic and end-point biomechanical and histologic data...
  25. ncbi request reprint Factors predicting hospital stay, operative time, blood loss, and transfusion in patients undergoing revision posterior lumbar spine decompression, fusion, and segmental instrumentation
    Fengyu Zheng
    Spine Service, Hospital for Special Surgery, Weill Medical College of Cornell University, New York, New York, USA
    Spine (Phila Pa 1976) 27:818-24. 2002
    ..A retrospective chart review was conducted for 112 patients who underwent revision posterior lumbar spine decompression, fusion, and segmental instrumentation...
  26. ncbi request reprint Animal models for preclinical assessment of bone morphogenetic proteins in the spine
    Harvinder S Sandhu
    Spinal Surgical Service, Hospital for Special Surgery, New York, New York 10021, USA
    Spine (Phila Pa 1976) 27:S32-8. 2002
    ..A review of the rationale behind the use of animal models for the assessment of bone morphogenetic proteins (BMPs) in the spine...
  27. ncbi request reprint Use of recombinant human bone morphogenetic protein-2 in spinal fusion applications
    Bill McKay
    Medtronic Sofamor Danek, Memphis, Tennessee 38132, USA
    Spine (Phila Pa 1976) 27:S66-85. 2002
  28. ncbi request reprint Gene therapy for spinal applications
    Chisa Hidaka
    Hospital for Special Surgery, Belfer Gene Therapy Core Facility, Weill Medical College of Cornell University, New York, NY, USA
    Orthop Clin North Am 33:439-46. 2002
    ..In the future, a series of vectors with multiple genes that are regulated by physiologic cues might be used to enhance spinal fusion, restore IVD tissue, or support spinal cord healing...
  29. ncbi request reprint Major vascular injury during anterior lumbar spinal surgery: incidence, risk factors, and management
    Gary A Fantini
    Hospital for Special Surgery, Weill Medical College of Cornell University, New York, New York, USA
    Spine (Phila Pa 1976) 32:2751-8. 2007
    ..Retrospective chart review...
  30. ncbi request reprint Bone morphogenetic proteins: relevance in spine surgery
    Safdar N Khan
    Hospital for Special Surgery, 535 E 70th Street, New York, NY 10021, USA
    Orthop Clin North Am 33:447-63, ix. 2002
    ..Gene therapy techniques producing in vivo osteoinductive factors and utilizing minimally invasive approaches are attractive options being developed for the future...
  31. ncbi request reprint Summary statement: emerging techniques for treatment of degenerative lumbar disc disease
    Howard An
    Spine (Phila Pa 1976) 28:S24-5. 2003
    ..Before wide application, the advantages and disadvantages of each procedure must be considered in lieu of inadequate study design and the lack of sufficient long-term outcome studies...
  32. ncbi request reprint Use of osteopromotive growth factors, demineralized bone matrix, and ceramics to enhance spinal fusion
    Safdar N Khan
    Department of Orthopaedic Surgery, University of California at Davis, Sacramento, CA, USA
    J Am Acad Orthop Surg 13:129-37. 2005
    ..They have the advantage of variable porosity, low cost, and ease of manufacture. Hydroxyapatite/tricalcium phosphate ceramics have been shown to perform as well as autogenous bone grafts but with fewer complications...
  33. ncbi request reprint The biology of bone grafting
    Safdar N Khan
    Department of Orthopaedic Surgery, The University of California, Davis, Davis, CA, USA
    J Am Acad Orthop Surg 13:77-86. 2005
    ....
  34. ncbi request reprint The current status of lumbar total disc replacement
    Russel C Huang
    Orthopaedic Spine Surgery, University Hospitals of Cleveland Case Western Reserve University, 11100 Euclid Avenue, BHC 5128, Cleveland, OH 44106, USA
    Orthop Clin North Am 35:33-42. 2004
    ..Finally, it is essential that practitioners understand that a limited subset of patients are good candidates for TDR and that indiscriminate application of this technology will result in poor outcomes...
  35. ncbi request reprint Accuracy of single-time, multilevel registration in image-guided spinal surgery
    Elias C Papadopoulos
    Spine Service, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA
    Spine J 5:263-7; discussion 268. 2005
    ..Consequently, current protocols suggest registering each spinal level (single-level registration) separately before pedicle screw placement at that level, a time-consuming process...