J E Salmon

Summary

Affiliation: Hospital for Special Surgery
Country: USA

Publications

  1. pmc Complement activation induces dysregulation of angiogenic factors and causes fetal rejection and growth restriction
    Guillermina Girardi
    Autoimmunity and Inflammation Program, Hospital for Special Surgery, Weill Medical College, Cornell University, New York, NY 10021, USA
    J Exp Med 203:2165-75. 2006
  2. pmc Complement C3 activation is required for antiphospholipid antibody-induced fetal loss
    V Michael Holers
    Department of Medicine, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    J Exp Med 195:211-20. 2002
  3. pmc Subclinical atherosclerosis in rheumatoid arthritis and systemic lupus erythematosus
    Jane E Salmon
    Mary Kirkland Center for Lupus Research, Hospital for Special Surgery, New York, New York 10021, USA
    Am J Med 121:S3-8. 2008
  4. pmc Pathogenic role of antiphospholipid antibodies
    J E Salmon
    Department of Medicine, Hospital for Special Surgery, Weill Medical College of Cornell University, New York, New York 10021, USA
    Lupus 17:405-11. 2008
  5. pmc Theodore E. Woodward Award: antiphospholipid syndrome revisited: a disorder initiated by inflammation
    Jane E Salmon
    Department of Medicine, Weill Medical College of Cornell University, New York, NY 10021, USA
    Trans Am Clin Climatol Assoc 118:99-114. 2007
  6. ncbi request reprint Activation of complement mediates antiphospholipid antibody-induced pregnancy loss
    J E Salmon
    Department of Medicine, Hospital for Special Surgery Weill Medical College, Cornell University, New York, NY 10021, USA
    Lupus 12:535-8. 2003
  7. pmc Antiphospholipid antibodies and pregnancy loss: a disorder of inflammation
    Jane E Salmon
    Autoimmunity and Inflammation Program, Hospital for Special Surgery, Department of Medicine, Weill Medical College of Cornell University, New York, NY 10021, USA
    J Reprod Immunol 77:51-6. 2008
  8. ncbi request reprint The role of complement in the antiphospholipid syndrome
    Jane E Salmon
    Department of Medicine, Hospital for Special Surgery Weill Medical College of Cornell University, New York, N Y, USA
    Curr Dir Autoimmun 7:133-48. 2004
  9. ncbi request reprint New insights into complement: a mediator of injury and marker of disease activity in systemic lupus erythematosus
    S Manzi
    Lupus Center of Excellence, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
    Lupus 13:298-303. 2004
  10. pmc A noninflammatory pathway for pregnancy loss: innate immune activation?
    Jane E Salmon
    Department of Medicine, Hospital for Special Surgery, Weill Medical College of Cornell University, New York, New York 10021, USA
    J Clin Invest 114:15-7. 2004

Research Grants

Collaborators

Detail Information

Publications54

  1. pmc Complement activation induces dysregulation of angiogenic factors and causes fetal rejection and growth restriction
    Guillermina Girardi
    Autoimmunity and Inflammation Program, Hospital for Special Surgery, Weill Medical College, Cornell University, New York, NY 10021, USA
    J Exp Med 203:2165-75. 2006
    ..These studies provide the first evidence linking the complement system to angiogenic factor imbalance associated with placental dysfunction, and identify a new effector of immune-triggered pregnancy complications...
  2. pmc Complement C3 activation is required for antiphospholipid antibody-induced fetal loss
    V Michael Holers
    Department of Medicine, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    J Exp Med 195:211-20. 2002
    ..While antigenic epitopes recognized by aPL antibodies are important in the pathogenesis of APS, our data show that in vivo complement activation is required for aPL antibody-induced fetal loss and growth retardation...
  3. pmc Subclinical atherosclerosis in rheumatoid arthritis and systemic lupus erythematosus
    Jane E Salmon
    Mary Kirkland Center for Lupus Research, Hospital for Special Surgery, New York, New York 10021, USA
    Am J Med 121:S3-8. 2008
    ..These data support the hypothesis that inflammation associated with RA and SLE contributes to accelerated atherosclerosis and argue that RA and SLE disease activity should be more aggressively managed...
  4. pmc Pathogenic role of antiphospholipid antibodies
    J E Salmon
    Department of Medicine, Hospital for Special Surgery, Weill Medical College of Cornell University, New York, New York 10021, USA
    Lupus 17:405-11. 2008
    ..We will discuss the current knowledge on how aPL antibodies trigger increased inflammation and enhanced thrombotic tendency, and thereby lead to tissue damage...
  5. pmc Theodore E. Woodward Award: antiphospholipid syndrome revisited: a disorder initiated by inflammation
    Jane E Salmon
    Department of Medicine, Weill Medical College of Cornell University, New York, NY 10021, USA
    Trans Am Clin Climatol Assoc 118:99-114. 2007
    ..Our studies underscore the importance of inflammation in fetal injury associated with aPL antibodies and emphasize the importance of developing and testing targeted complement inhibitory therapy for patients with APS...
  6. ncbi request reprint Activation of complement mediates antiphospholipid antibody-induced pregnancy loss
    J E Salmon
    Department of Medicine, Hospital for Special Surgery Weill Medical College, Cornell University, New York, NY 10021, USA
    Lupus 12:535-8. 2003
    ....
  7. pmc Antiphospholipid antibodies and pregnancy loss: a disorder of inflammation
    Jane E Salmon
    Autoimmunity and Inflammation Program, Hospital for Special Surgery, Department of Medicine, Weill Medical College of Cornell University, New York, NY 10021, USA
    J Reprod Immunol 77:51-6. 2008
    ..These studies underscore the importance of inflammation in fetal injury associated with aPL antibodies and raise the importance of developing and testing targeted complement inhibitory therapy for patients with APS...
  8. ncbi request reprint The role of complement in the antiphospholipid syndrome
    Jane E Salmon
    Department of Medicine, Hospital for Special Surgery Weill Medical College of Cornell University, New York, N Y, USA
    Curr Dir Autoimmun 7:133-48. 2004
    ....
  9. ncbi request reprint New insights into complement: a mediator of injury and marker of disease activity in systemic lupus erythematosus
    S Manzi
    Lupus Center of Excellence, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
    Lupus 13:298-303. 2004
    ....
  10. pmc A noninflammatory pathway for pregnancy loss: innate immune activation?
    Jane E Salmon
    Department of Medicine, Hospital for Special Surgery, Weill Medical College of Cornell University, New York, New York 10021, USA
    J Clin Invest 114:15-7. 2004
    ....
  11. pmc Mutations in complement regulatory proteins predispose to preeclampsia: a genetic analysis of the PROMISSE cohort
    Jane E Salmon
    Autoimmunity and Inflammation Program, Hospital for Special Surgery, Cornell Weill Medical College, New York, New York, USA
    PLoS Med 8:e1001013. 2011
    ..Our previous studies in mice indicate that complement activation targeted to the placenta drives angiogenic imbalance and placental insufficiency...
  12. ncbi request reprint The antiphospholipid syndrome as a disorder initiated by inflammation: implications for the therapy of pregnant patients
    Jane E Salmon
    Mary Kirkland Center for Lupus Research, New York, NY, USA
    Nat Clin Pract Rheumatol 3:140-7; quiz 1 p following 187. 2007
    ..This Review describes the potential mechanisms of tissue injury by antiphospholipid antibodies, the management of pregnant patients with APS and how heparin therapy might inhibit the pathogenic mediators of disease...
  13. pmc Complement activation as a mediator of antiphospholipid antibody induced pregnancy loss and thrombosis
    J E Salmon
    Department of Medicine, Hospital for Special Surgery Weill Medical College, Cornell University, New York 10021, USA
    Ann Rheum Dis 61:ii46-50. 2002
  14. ncbi request reprint Anti-heparin platelet factor 4 antibodies in systemic lupus erythematosus are associated with IgM antiphospholipid antibodies and the antiphospholipid syndrome
    D Alpert
    Department of Rheumatology, Hospital for Special Surgery, New York, USA
    Ann Rheum Dis 67:395-401. 2008
    ..To investigate the prevalence and clinical correlates of anti-heparin platelet factor 4 antibodies (anti-HPF4) in systemic lupus erythematosus (SLE) patients with and without antiphospholipid antibodies (aPL)...
  15. ncbi request reprint Low-binding alleles of Fcgamma receptor types IIA and IIIA are inherited independently and are associated with systemic lupus erythematosus in Hispanic patients
    R Zuniga
    Hospital for Special Surgery, New York, New York 10021, USA
    Arthritis Rheum 44:361-7. 2001
    ....
  16. pmc Serum complement activation on heterologous platelets is associated with arterial thrombosis in patients with systemic lupus erythematosus and antiphospholipid antibodies
    E I B Peerschke
    Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, New York 10029, USA
    Lupus 18:530-8. 2009
    ..039). Sera from patients with aPL possess an enhanced capacity for in-situ complement fixation on platelets. This capacity may influence arterial thrombosis risk in patients with SLE...
  17. ncbi request reprint Fc gamma receptor-mediated functions in neutrophils are modulated by adenosine receptor occupancy. A1 receptors are stimulatory and A2 receptors are inhibitory
    J E Salmon
    Department of Medicine, Hospital for Special Surgery, New York, NY 10021
    J Immunol 145:2235-40. 1990
    ..Our observation that adenosine analogs had more potent effects on adherent neutrophils emphasizes the potential importance of adenosine as a modulator of Fc gamma R-triggered inflammation in vivo...
  18. ncbi request reprint Characterization of the FcgammaRIIA promoter and 5'UTR sequences in patients with systemic lupus erythematosus
    L Pricop
    Department of Medicine, Hospital for Special Surgery and Weill Medical College of Cornell University New York, NY 10021, USA
    Genes Immun 3:S47-50. 2002
    ..Two novel SNPs have been identified in the distal region of the FcgammaRIIA promoter. The polymorphisms are present in both disease-free and SLE donors and do not associate with quantitative changes in FcgammaRIIa phagocytic function...
  19. doi request reprint Perceptions and measurements of physical activity in patients with systemic lupus erythematosus
    C A Mancuso
    Research Division and Division of Rheumatology, Hospital for Special Surgery, Weill Cornell Medical College, 535 East 70th Street, New York, NY 10021, USA
    Lupus 20:231-42. 2011
    ..Most patients believed physical activity provided long-term benefits for SLE and that they could be more physically active...
  20. ncbi request reprint Prevalence and relation to risk factors of carotid atherosclerosis and left ventricular hypertrophy in systemic lupus erythematosus and antiphospholipid antibody syndrome
    M J Roman
    Division of Cardiology, the New York Presbyterian Hospital Weill Cornell Medical Center, New York, USA
    Am J Cardiol 87:663-6, A11. 2001
    ..005) and left ventricular hypertrophy (32% vs 5%, p < 0.005), supporting the possibility that chronic inflammation predisposes to premature cardiovascular disease in SLE...
  21. ncbi request reprint Human receptors for immunoglobulin G: key elements in the pathogenesis of rheumatic disease
    J E Salmon
    Hospital for Special Surgery and Weill Medical College of Cornell University, New York, New York 10021, USA
    Arthritis Rheum 44:739-50. 2001
    ..Expansion in our knowledge of structure-function relationships among Fc gammaR has identified them as heritable risk factors for disease susceptibility and valuable targets for therapeutic modulation of the immune system...
  22. ncbi request reprint Human mononuclear phagocytes express adenosine A1 receptors. A novel mechanism for differential regulation of Fc gamma receptor function
    J E Salmon
    Department of Medicine, Hospital for Special Surgery, New York, NY 10021
    J Immunol 151:2775-85. 1993
    ..This rapid and potent modulation of Fc gamma receptor-mediated function suggests that adenosine is an important local regulator of the inflammatory response...
  23. ncbi request reprint Differential modulation of stimulatory and inhibitory Fc gamma receptors on human monocytes by Th1 and Th2 cytokines
    L Pricop
    Department of Medicine, Hospital for Special Surgery and Weill Medical College of Cornell University, New York, NY 10021, USA
    J Immunol 166:531-7. 2001
    ....
  24. pmc A novel polymorphism of FcgammaRIIIa (CD16) alters receptor function and predisposes to autoimmune disease
    J Wu
    Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    J Clin Invest 100:1059-70. 1997
    ..Thus, the FcgammaRIIIa polymorphism at residue 176 appears to impact directly on human biology, an effect which may extend beyond autoimmune disease characterized by immune complexes to host defense mechanisms...
  25. ncbi request reprint A pilot study of office-based spirometry in patients with systemic lupus erythematosus
    C A Mancuso
    Research Division, Hospital for Special Surgery, Weill Cornell Medical College, New York, New York 10021, USA
    Lupus 21:1343-50. 2012
    ..The goals of this study were to describe pulmonary function measured by office-based spirometry in patients with SLE and to compare spirometry with physical activity and systemic fatigue...
  26. pmc Novel Fc gamma receptor I family gene products in human mononuclear cells
    A J Porges
    Hospital for Special Surgery, Cornell University Medical College, New York 10021
    J Clin Invest 90:2102-9. 1992
    ....
  27. pmc Fc gamma RIIA alleles are heritable risk factors for lupus nephritis in African Americans
    J E Salmon
    Department of Medicine, Graduate Program in Immunology, The Cornell University Medical College, New York 10021, USA
    J Clin Invest 97:1348-54. 1996
    ..The skewing in the distribution of Fc gamma RIIA alleles identifies this gene as a risk factor with pathophysiologic importance for the SLE diathesis in African Americans...
  28. ncbi request reprint The complement system in the pathophysiology of pregnancy
    Guillermina Girardi
    Department of Medicine, Hospital for Special Surgery, Weill Medical College of Cornell University, New York, NY 10021, USA
    Mol Immunol 43:68-77. 2006
    ..The role played by the complement system in the fetal damage induced by anti-phospholipid antibodies in a mouse model will be examined...
  29. ncbi request reprint Subclinical carotid atherosclerosis in a patient with systemic lupus erythematosus
    Deborah Alpert
    Department of Rheumatology, Hospital for Special Surgery, New York, NY, USA
    Nat Clin Pract Rheumatol 3:473-8; quiz, 2nd following 478. 2007
    ..During this time she participated in an observational study to evaluate risk factors for the development of subclinical atherosclerosis in patients with SLE...
  30. pmc Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome
    Guillermina Girardi
    Department of Medicine, Hospital for Special Surgery Weill Medical College, Cornell University, 535 East 70th Street, New York, New York 10021, USA
    J Clin Invest 112:1644-54. 2003
    ..Our findings identify the key innate immune effectors engaged by pathogenic autoantibodies that mediate poor pregnancy outcomes in APS and provide novel and important targets for prevention of pregnancy loss in APS...
  31. ncbi request reprint Rate and determinants of progression of atherosclerosis in systemic lupus erythematosus
    Mary J Roman
    Weill Medical College of Cornell University, and the Hospital for Special Surgery, New York, New York 10021, USA
    Arthritis Rheum 56:3412-9. 2007
    ..To determine the rate of atherosclerosis progression as well as the relationship of traditional risk factors, systemic lupus erythematosus (SLE)-related factors, and treatment to atherosis progression in SLE patients...
  32. doi request reprint Insoluble immune complexes are most effective at triggering IL-10 production in human monocytes and synergize with TLR ligands and C5a
    Stephen J DiMartino
    Hospital for Special Surgery, Weill Medical College, Cornell University, 535 East 70th Street, New York, NY 10021, USA
    Clin Immunol 127:56-65. 2008
    ..Using an in vitro model, we studied how IC solubility, complement activation products, and TLR ligands could affect IL-10 production by human monocytes stimulated with ICs...
  33. doi request reprint Infliximab treatment shifts the balance between stimulatory and inhibitory Fcgamma receptor type II isoforms on neutrophils in patients with rheumatoid arthritis
    Kristina Belostocki
    Hospital for Special Surgery, Weill Medical College of Cornell University, New York, New York 10021, USA
    Arthritis Rheum 58:384-8. 2008
    ..This study was undertaken to determine whether TNFalpha blockade in patients with rheumatoid arthritis (RA) alters the balance of activating FcgammaR and inhibitory FcgammaR and thereby decreases inflammation...
  34. pmc Inhibition of interleukin 10 signaling after Fc receptor ligation and during rheumatoid arthritis
    Jong Dae Ji
    Department of Medicine Hospital for Special Surgery, 535 East 70th St, New York, NY 10021, USA
    J Exp Med 197:1573-83. 2003
    ..Generation of macrophages refractory to IL-10 can contribute to pathogenesis of inflammatory and infectious diseases characterized by production of interferon-gamma and immune complexes...
  35. pmc Excessive complement activation is associated with placental injury in patients with antiphospholipid antibodies
    Jaime M Shamonki
    Department of Pathology, New York Presbyterian Hospital Weill Medical College, Cornell University, New York, NY 10021, USA
    Am J Obstet Gynecol 196:167.e1-5. 2007
    ..We examined the placentas of patients with APAs to demonstrate a similar association with tissue injury in humans...
  36. ncbi request reprint Prevalence and correlates of accelerated atherosclerosis in systemic lupus erythematosus
    Mary J Roman
    Division of Cardiology, Weill Medical College of Cornell University, The Hospital for Special Surgery, New York, NY 10021, USA
    N Engl J Med 349:2399-406. 2003
    ....
  37. ncbi request reprint Heparin prevents antiphospholipid antibody-induced fetal loss by inhibiting complement activation
    Guillermina Girardi
    Department of Medicine, Hospital for Special Surgery and Weill Medical College, Cornell University, 535 East 70th Street, New York, New York 10021, USA
    Nat Med 10:1222-6. 2004
    ..Our data indicate that heparins prevent obstetrical complications in women with APS because they block activation of complement induced by aPL antibodies targeted to decidual tissues, rather than by their anticoagulant effects...
  38. ncbi request reprint FcgammaRIIa is a target for modulation by TNFalpha in human neutrophils
    Kristina Belostocki
    Hospital for Special Surgery, Weill Medical College of Cornell University, Department of Medicine and Research Division, New York, NY 10021, USA
    Clin Immunol 117:78-86. 2005
    ....
  39. ncbi request reprint Preclinical carotid atherosclerosis in patients with rheumatoid arthritis
    Mary J Roman
    Division of Cardiology, Weill Medical College of Cornell University, Hospital for Special Surgery, and The Rogosin Institute, New York, New York 10021, USA
    Ann Intern Med 144:249-56. 2006
    ..Rheumatoid arthritis is associated with increased morbidity and mortality because of cardiovascular disease, independent of traditional risk factors...
  40. pmc Autoantibody selection and production in early human life
    Eric Meffre
    Hospital for Special Surgery, Weill Medical College of Cornell University, New York, NY 10021, USA
    J Clin Invest 117:598-601. 2007
    ..We present a molecular basis for the limited and common repertoire of antibodies produced by fetal B cells, which may be distinct from the abnormalities in B cell development described in patients with autoimmune diseases...
  41. ncbi request reprint TNF-alpha is a critical effector and a target for therapy in antiphospholipid antibody-induced pregnancy loss
    Jessica Berman
    Department of Medicine, Hospital for Special Surgery Weill Medical College of Cornell University, 535 East 70th Street, New York, NY 10021, USA
    J Immunol 174:485-90. 2005
    ..Our results suggest that TNF-alpha links pathogenic aPL Abs to fetal damage and identify TNF blockade as a potential therapy for the pregnancy complications of APS...
  42. ncbi request reprint Arterial stiffness in chronic inflammatory diseases
    Mary J Roman
    Division of Cardiology, Weill Medical College, Cornell University, 525 East 68th St, New York, NY 10021, USA
    Hypertension 46:194-9. 2005
    ....
  43. pmc Complement activation fragment Bb in early pregnancy and spontaneous preterm birth
    Anne M Lynch
    Department of Obstetrics and Gynecology, University of Colorado Denver, Denver, CO 80045, USA
    Am J Obstet Gynecol 199:354.e1-8. 2008
    ....
  44. ncbi request reprint Genetic linkage and association of Fcgamma receptor IIIA (CD16A) on chromosome 1q23 with human systemic lupus erythematosus
    Jeffrey C Edberg
    University of Alabama at Birmingham, Birmingham, Alabama 35294 0006, USA
    Arthritis Rheum 46:2132-40. 2002
    ....
  45. ncbi request reprint Redox regulation of Fcgamma receptor-mediated phagocytosis: implications for host defense and tissue injury
    Luminita Pricop
    Hospital for Special Surgery and Weill Medical College of Cornell University, Department of Medicine, New York, NY 10021, USA
    Antioxid Redox Signal 4:85-95. 2002
    ..This review will focus on the cross-talk between Fcgamma receptors and reactive oxygen intermediates at sites of inflammation and its role in microbial immunity...
  46. ncbi request reprint Soluble mediators as therapeutic targets in systemic lupus erythematosus: cytokines, immunoglobulin receptors, and the complement system
    Kyriakos A Kirou
    Weill Medical College of Cornell University, New York, NY, USA
    Rheum Dis Clin North Am 32:103-19, ix. 2006
    ....
  47. ncbi request reprint Are we coming to terms with tumor necrosis factor inhibition in pregnancy?
    Jane E Salmon
    Arthritis Rheum 54:2353-5. 2006
  48. pmc Alternative complement pathway activation fragment Bb in early pregnancy as a predictor of preeclampsia
    Anne M Lynch
    Department of Obstetrics and Gynecology, University of Colorado at Denver and Health Sciences Center, Denver, CO, USA
    Am J Obstet Gynecol 198:385.e1-9. 2008
    ..The purpose of this study was to determine whether elevated levels of the activation fragment Bb in early pregnancy are predictive of preeclampsia...
  49. ncbi request reprint Relationship of antiphospholipid antibodies to cardiovascular manifestations of systemic lupus erythematosus
    Afshin Farzaneh-Far
    Hospital for Special Surgery, Weill Medical College of Cornell University, New York, New York 10021, USA
    Arthritis Rheum 54:3918-25. 2006
    ..We undertook this study to examine the relationships of aPL with valvular, myocardial, and arterial disease in SLE...
  50. ncbi request reprint Role of the Fcgamma receptor IIA polymorphism in the antiphospholipid syndrome: an international meta-analysis
    Fotini B Karassa
    University of Ioannina School of Medicine, Ioannina, Greece
    Arthritis Rheum 48:1930-8. 2003
    ..To assess the impact of the FcgammaRIIA-R/H131 polymorphism on the risk for antiphospholipid syndrome (APS), both primary and secondary to systemic lupus erythematosus (SLE)...
  51. ncbi request reprint FcgammaRIIB mediates C-reactive protein inhibition of endothelial NO synthase
    Chieko Mineo
    Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Circ Res 97:1124-31. 2005
    ..Thus FcgammaRIIB mediates CRP inhibition of eNOS via PP2A, providing a mechanistic link between CRP and endothelial dysfunction...
  52. pmc Tissue factor: a link between C5a and neutrophil activation in antiphospholipid antibody induced fetal injury
    Patricia Redecha
    Hospital for Special Surgery, Department of Medicine, Weill Medical College of Cornell University, New York, NY 10021, USA
    Blood 110:2423-31. 2007
    ..The identification of TF as an important mediator of C5a-induced oxidative burst in neutrophils in aPL-induced fetal injury provides a new target for therapy to prevent pregnancy loss in the antiphospholipid syndrome...
  53. pmc Fetal gene defects precipitate platelet-mediated pregnancy failure in factor V Leiden mothers
    Rashmi Sood
    Blood Research Institute, Blood Center of Wisconsin, Milwaukee, WI 53226, USA
    J Exp Med 204:1049-56. 2007
    ..e., thrombosis or pregnancy loss), depending on the vascular bed in which this interaction occurs...
  54. ncbi request reprint Systemic lupus erythematosus predicts increased left ventricular mass
    Janice Pieretti
    Division of Cardiology, Weill Medical College of Cornell University and the Hospital for Special Surgery, New York, NY 10021, USA
    Circulation 116:419-26. 2007
    ..Whether SLE alters left ventricular (LV) structure and function in the absence of valvular and clinical coronary artery disease is unknown...

Research Grants32

  1. Complement as a Mediator of Recurrent Miscarriages
    Jane Salmon; Fiscal Year: 2007
    ..In addition, our studies will provide insights into mechanisms by which complement-induces disease and suggest means to prevent, arrest, or modify complement-mediated inflammatory disorders. ..
  2. Mechanisms of aPL antibody-induced pregnancy loss
    Jane Salmon; Fiscal Year: 2007
    ..Additionally, understanding how aPL antibodies "cause" pregnancy loss may translate into new concepts about maternal-fetal tolerance and miscarriages in general and benefit women with non-APS- related pregnancy complications. ..
  3. Predictors of Pregnancy Outcome in SLE and APS
    Jane Salmon; Fiscal Year: 2007
    ..The identification of such surrogate markers in aPL and SLE patients may also prove generally applicable to anticipate complications during pregnancy in disease-free women. ..
  4. Mechanism of aPL antibody-induced Pregnancy loss
    Jane Salmon; Fiscal Year: 2009
    ..Additionally, understanding how aPL antibodies "cause" pregnancy loss may translate into new concepts about maternal-fetal tolerance and miscarriages in general and benefit women with non-APS- related pregnancy complications. ..
  5. Mechanism of aPL antibody-induced Pregnancy loss
    Jane E Salmon; Fiscal Year: 2010
    ..Additionally, understanding how aPL antibodies "cause" pregnancy loss may translate into new concepts about maternal-fetal tolerance and miscarriages in general and benefit women with non-APS- related pregnancy complications. ..
  6. Predictors of Pregnancy Outcome in SLE and APS
    Jane E Salmon; Fiscal Year: 2010
    ....
  7. Predictors of Pregnancy Outcome in SLE and APS
    Jane Salmon; Fiscal Year: 2009
    ....
  8. HLA-ASSOCIATED FC RECEPTOR FUNCTION IN NORMALS AND SLE
    Jane Salmon; Fiscal Year: 1993
  9. FC RECEPTOR FUNCTION IN NORMALS AND SLE
    Jane Salmon; Fiscal Year: 2001
    ..to define subclasses of IgG deposited within glomeruli in lupus nephritis and their relationships to FcgRIIa alleles, autoantibodies, and induction of glomerular injury. ..
  10. Targets for New Therapeutics for SLE
    Jane Salmon; Fiscal Year: 2002
    ..abstract_text> ..