MARIA BURNATOWSKA-HLEDIN

Summary

Affiliation: Hope College
Country: USA

Publications

  1. ncbi request reprint VACM-1, a cullin gene family member, regulates cellular signaling
    M Burnatowska-Hledin
    Departments of Biology and Chemistry, Peale Science Center, Hope College, Holland, Michigan 49422 9000, USA
    Am J Physiol Cell Physiol 279:C266-73. 2000
  2. ncbi request reprint Expression of VACM-1 protein in cultured rat adrenal endothelial cells is linked to the cell cycle
    - Burnatowska-Hledin
    Department of Biology, Peale Science Center, Hope College, Holland, MI 49422 9000, USA
    Endothelium 8:49-63. 2001
  3. ncbi request reprint T47D breast cancer cell growth is inhibited by expression of VACM-1, a cul-5 gene
    Maria A Burnatowska-Hledin
    Department of Biology, Peale Science Center, Hope College, Holland, MI 49422 9000, USA
    Biochem Biophys Res Commun 319:817-25. 2004
  4. doi request reprint Using HPLC-mass spectrometry to teach proteomics concepts with problem-based techniques
    Michael Short
    Department of Chemistry, Hope College, Holland, Michigan 49423 Department of Biology, Hope College, Holland, Michigan 49423 Montana State University, Bozeman, Montana
    Biochem Mol Biol Educ 38:242-6. 2010
  5. pmc Phosphorylation of VACM-1/Cul5 by protein kinase A regulates its neddylation and antiproliferative effect
    Shirley E Bradley
    Department of Biology, Hope College, Holland, Michigan 49422 9000, USA
    J Biol Chem 285:4883-95. 2010

Research Grants

  1. VACM-1, cul 5 gene regulates cell growth & angiogenesis.
    Maria Burnatowska Hledin; Fiscal Year: 2004

Collaborators

  • Ping Zhao
  • Maria Burnatowska Hledin
  • Michael Short
  • Shirley E Bradley
  • - Burnatowska-Hledin
  • Elizabeth Oosterhouse
  • Alyssa E Johnson
  • Michael Seymour
  • Isabelle P Le
  • Anne Short
  • Gabriel A Marquez
  • Rachel Vankempen
  • Michael P Hledin
  • C Barney
  • P Clare
  • P I Lelkes
  • J Grobe
  • A Roulo
  • A Zeneberg

Detail Information

Publications5

  1. ncbi request reprint VACM-1, a cullin gene family member, regulates cellular signaling
    M Burnatowska-Hledin
    Departments of Biology and Chemistry, Peale Science Center, Hope College, Holland, Michigan 49422 9000, USA
    Am J Physiol Cell Physiol 279:C266-73. 2000
    ..Our data demonstrate that VACM-1, the first mammalian cullin protein to be characterized, is involved in the regulation of signaling...
  2. ncbi request reprint Expression of VACM-1 protein in cultured rat adrenal endothelial cells is linked to the cell cycle
    - Burnatowska-Hledin
    Department of Biology, Peale Science Center, Hope College, Holland, MI 49422 9000, USA
    Endothelium 8:49-63. 2001
    ..In summary, these results indicate that VACM-1 protein expression in RAMEC membrane is linked to the cell cycle, and consequently, VACM-1 may be involved in the regulation of cell division...
  3. ncbi request reprint T47D breast cancer cell growth is inhibited by expression of VACM-1, a cul-5 gene
    Maria A Burnatowska-Hledin
    Department of Biology, Peale Science Center, Hope College, Holland, MI 49422 9000, USA
    Biochem Biophys Res Commun 319:817-25. 2004
    ..Further, egr-1 protein levels were significantly lower in the nuclear fraction from VACM-1 transfected cells when compared to controls. These data indicate that VACM-1 is involved in the regulation of cellular growth...
  4. doi request reprint Using HPLC-mass spectrometry to teach proteomics concepts with problem-based techniques
    Michael Short
    Department of Chemistry, Hope College, Holland, Michigan 49423 Department of Biology, Hope College, Holland, Michigan 49423 Montana State University, Bozeman, Montana
    Biochem Mol Biol Educ 38:242-6. 2010
    ..This experiment demonstrates that complex concepts can be taught in the undergraduate biochemistry laboratory using a problem-based approach...
  5. pmc Phosphorylation of VACM-1/Cul5 by protein kinase A regulates its neddylation and antiproliferative effect
    Shirley E Bradley
    Department of Biology, Hope College, Holland, Michigan 49422 9000, USA
    J Biol Chem 285:4883-95. 2010
    ..These results suggest that the antiproliferative effect of VACM-1/Cul5 is dependent on its posttranslational modifications and will help in the design of new anticancer therapeutics that target the Nedd8 pathway...

Research Grants1

  1. VACM-1, cul 5 gene regulates cell growth & angiogenesis.
    Maria Burnatowska Hledin; Fiscal Year: 2004
    ..Consequently, these results may lead to development of strategies for diagnosis and intervention in the pathologies of excessive vascularization and consequently cancer. ..