Dwight R Stickney

Summary

Affiliation: Hollis-Eden Pharmaceuticals
Country: USA

Publications

  1. ncbi 5-androstenediol stimulates multilineage hematopoiesis in rhesus monkeys with radiation-induced myelosuppression
    Dwight R Stickney
    Hollis Eden Pharmaceuticals, Inc, 4435 Eastgate Mall, Suite 400, San Diego, CA 92121, USA
    Int Immunopharmacol 6:1706-13. 2006
  2. ncbi 5-androstenediol improves survival in clinically unsupported rhesus monkeys with radiation-induced myelosuppression
    Dwight R Stickney
    Hollis Eden Pharmaceuticals Inc, San Diego, CA 92121, USA
    Int Immunopharmacol 7:500-5. 2007
  3. ncbi Safety and activity of the immune modulator HE2000 on the incidence of tuberculosis and other opportunistic infections in AIDS patients
    Dwight R Stickney
    Hollis Eden Pharmaceuticals, Inc, 4435 Eastgate Mall, Suite 400, San Diego, CA 92121, USA
    Antimicrob Agents Chemother 51:2639-41. 2007
  4. ncbi Reduction of parasite levels in patients with uncomplicated malaria by treatment with HE2000
    James M Frincke
    Hollis Eden Pharmaceuticals, San Diego, California 92121, USA
    Am J Trop Med Hyg 76:232-6. 2007
  5. ncbi Preliminary clinical findings on NEUMUNE as a potential treatment for acute radiation syndrome
    Dwight R Stickney
    Harbor Biosciences, 9171 Towne Centre Drive, San Diego, CA 92122, USA
    J Radiol Prot 30:687-98. 2010
  6. ncbi Phase I and Phase II clinical trials of androst-5-ene-3β,7β,17β-triol
    Dwight R Stickney
    Harbor Biosciences, Inc 9171 Towne Centre Drive, Suite 180, San Diego, CA 92122, USA
    Am J Transl Res 3:275-83. 2011

Detail Information

Publications6

  1. ncbi 5-androstenediol stimulates multilineage hematopoiesis in rhesus monkeys with radiation-induced myelosuppression
    Dwight R Stickney
    Hollis Eden Pharmaceuticals, Inc, 4435 Eastgate Mall, Suite 400, San Diego, CA 92121, USA
    Int Immunopharmacol 6:1706-13. 2006
    ..AED, as a single agent, promotes multilineage hematopoietic recovery of the bone marrow. These data suggest that it may play an important therapeutic role in the management of acute radiation syndrome...
  2. ncbi 5-androstenediol improves survival in clinically unsupported rhesus monkeys with radiation-induced myelosuppression
    Dwight R Stickney
    Hollis Eden Pharmaceuticals Inc, San Diego, CA 92121, USA
    Int Immunopharmacol 7:500-5. 2007
    ..01). The accumulation of days of neutropenia (ANC<500 cells/microL) up to day 14 plays no major role in predicting death. AED shows significant activity in irradiated primates with acute hematopoietic radiation syndrome...
  3. ncbi Safety and activity of the immune modulator HE2000 on the incidence of tuberculosis and other opportunistic infections in AIDS patients
    Dwight R Stickney
    Hollis Eden Pharmaceuticals, Inc, 4435 Eastgate Mall, Suite 400, San Diego, CA 92121, USA
    Antimicrob Agents Chemother 51:2639-41. 2007
    ..2% (P < 0.05) and the cumulative incidence of opportunistic infections (P < 0.05). These results warrant further clinical investigation of HE2000...
  4. ncbi Reduction of parasite levels in patients with uncomplicated malaria by treatment with HE2000
    James M Frincke
    Hollis Eden Pharmaceuticals, San Diego, California 92121, USA
    Am J Trop Med Hyg 76:232-6. 2007
    ..HE2000 shows a safety profile and pharmacologic activity worthy of further investigation to understand its role in the treatment of malaria, perhaps in combination with anti-malarial agents...
  5. ncbi Preliminary clinical findings on NEUMUNE as a potential treatment for acute radiation syndrome
    Dwight R Stickney
    Harbor Biosciences, 9171 Towne Centre Drive, San Diego, CA 92122, USA
    J Radiol Prot 30:687-98. 2010
    ..Findings suggest that parenteral administration of 5-AED in aqueous suspension may be a safe and effective means to stimulate innate immunity and alleviate neutropenia and thrombocytopenia associated with ARS...
  6. ncbi Phase I and Phase II clinical trials of androst-5-ene-3β,7β,17β-triol
    Dwight R Stickney
    Harbor Biosciences, Inc 9171 Towne Centre Drive, Suite 180, San Diego, CA 92122, USA
    Am J Transl Res 3:275-83. 2011
    ..The utility of βAET in humans may be limited to maintenance of homeostasis in healthy adults...