R S Hoffman

..Public health efforts should focus on greater restrictions on access to, and use of, thallium salts...

..This study was designed to further investigate the pharmacologic effects of EME...

..The following study was designed to further assess the relationship between cocaine use and plasma cholinesterase activity...

..A case of thallium poisoning that began during the first trimester of pregnancy and resulted in fetal demise is reported...

..This experiment was designed to compare the relative thallium binding efficacy of these agents in a standard isotherm model...

..Our results suggest that PCh activity is an important determinant of cocaine toxicity. This effect appears to be independent of either RBCCh activity or manifestations of organophosphate intoxication...

..Since reporting of adverse events associated with tumescent liposuction is not mandatory, the incidence of complications and deaths is unknown...

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..Computed tomography of her head revealed pneumocephalus. She recovered fully over the course of 24 hours. Intrathecal injection during a trigger-point injection is a previously unreported complication of trigger-point injection therapy...

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..Acute clenbuterol toxicity is rarely reported following illicit use in humans, and this is the first such case to provide confirmatory toxicological analysis...

..This study characterizes the ongoing epidemic of acute cholinesterase inhibitor poisoning due to an illicit rodenticide and identifies its etiology...

..This case of apparently safe and effective pralidoxime use without concomitant atropine administration in a patient with carbamate toxicity reinforces recent data demonstrating the potential safety of pralidoxime in carbamate toxicity...

..These innovative approaches are designed to challenge dogma and provide a stimulus for individualised clinical care...

..Internal use of 'camphor' is a potential public health concern in Accra. We sought to identify the toxins being sold as mothballs in Greater Accra and use this information to help educate both clinicians and the public...

..To report a case of seizures and supraventricular tachycardia (SVT) following confirmed synthetic cannabinoid ingestion...

..To determine the prevalence of herbal preparation use among patients presenting to an urban teaching hospital ED...

..To our knowledge, this is the first reported use of digoxin Fab fragments to treat toad venom poisoning...

..We report the first intentional overdose with levetiracetam including clinical effects and serial serum concentrations...

..The symptoms could be due to vasodilation from increased levels of NO, though other etiologies cannot be excluded. AAKG containing supplements may be associated with adverse effects requiring hospital admission...

..These cases show the importance of confirming the absence of drug packets in the gastrointestinal (GI) tract as the definitive end-point in the treatment of body-packers...

..We report 2 cases of hyperkalemia in patients with normal renal function who developed hyperkalemia after ingesting sustained-release potassium preparations and describe the use of radiography and whole-bowel irrigation in their care...

..The authors hypothesized that the presence of methadone and a TCA, a BZD, or both is associated with an "accidental" overdose (AOD) death more often than a death from any other cause...

..A serum ephedrine level, drawn approximately 6 to 7 hr after ingestion, was 150 ng/mL. She was discharged from the hospital after being instructed to avoid ephedrine-containing products...

..This case helps to highlight the risks of beta adrenergic receptor antagonists in patients with chest pain associated with cocaine use...

..We report the unique case of a 21-y-old woman who steeped a fentanyl patch in a cup of hot water and then drank the mixture. Coma and hypoventilation resulted. The woman was resuscitated with naloxone i.v. and recovered without sequelae...

..This investigation was prompted by an apparent increase in paraffin lamp oil exposures during the Jewish Sabbath, from sunset Friday until sunset Saturday, noted by the staff of our regional poison control center...

..The goal of the present study was to evaluate the role of 2-PAM in a mouse model of lethal carbaryl poisoning...

..While various modes of treatments have been used to treat the hypotension of CCB overdose, this is the first report to our knowledge of the successful use of vasopressin in this clinical setting...

..The authors' objective was to reassess the epidemiology and toxicity of medicinal cocaine use among otolaryngologists and to compare current trends in usage and safety data with previously reported data...

..Although clearly absorbed, strontium ferrite does not appear to produce acute toxicity. Delayed, and or chronic toxicity cannot be excluded based on this report...

..The emergency department (ED) evaluation of cocaine-associated acute coronary syndrome (CAACS) is often a diagnostic and therapeutic challenge...

..We investigated the effect of amiodarone and amitriptyline in a mouse lethality model...

..5 ng/ml during 6.25 mg twice daily dosing). Despite its unique pharmacological properties, the clinical manifestations of carvedilol overdose appear similar to other beta-adrenoreceptor antagonists...

..This study seeks to determine if FeCl3 can be used to identify salicylate-containing products...

..Like quinidine, amiodarone is a potassium channel blocker, although amiodarone is more familiar to clinicians due to its recent inclusion in advanced cardiac life support (ACLS) protocols...

..We present a case of citalopram overdose with a substantially delayed onset of cardiac toxicity...

..We describe severe toxicity associated with an overdose of amlodipine and valsartan...

..Limited experimental evidence provides support for antigenic cross-reactivity between Antivenin (Crotalidae) polyvalent and P nasutum venom...

..Although chemiluminescent plastic rods, commonly called "glow sticks" or "light sticks," are typically considered to be minimally toxic or nontoxic, published data about exposure to these products are scarce...

..We describe 3 cases of diphenhydramine-induced cardiac toxicity that were responsive to bicarbonate...

..To report a case in which a crushed extended-release (XL) nifedipine tablet contributed to a patient fatality...

..However, almost 30 years after these laws were passed, inner-city housing with leaded paint still exists. We describe three children living in New York City who developed plumbism from the ingestion of leaded paint chips...

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..A tiagabine level obtained on ED arrival was 420 ng/mL (therapeutic 20-103 ng/mL). The patient was discharged to psychiatry within 1 week with no neurologic sequelae...

..To report a case of erratic absorption, double peak serum concentrations, and hepatotoxicity following premature cessation of intravenous N-acetylcysteine (NAC) treatment in the setting of a massive acetaminophen overdose...

..A systematic review of CAS poisoning was performed to compare the mortality rate of cardenolides and bufadienolides...

..An empiric dose of 10 vials of digoxin-specific Fab might be beneficial in patients poisoned with an unknown cardioactive steroid...

..As no clinical laboratory can provide services to meet all needs, the National Academy of Clinical Biochemistry Committee recommends establishment of regional centers for specialized toxicology testing...

..In response, drug smugglers may begin using children as couriers, including using them as "body packers."..

..We reviewed the literature that pertains to the use of physostigmine to treat gamma-hydroxybutyrate-induced sedation...

..She regained consciousness completely within 48 hours of presentation and recovered uneventfully. MDMA toxicity, particularly the pathophysiology and treatment of MDMA-induced hyponatremia, are discussed...

..There were no complications. The patient recovered completely to his pre-morbid state. Double volume exchange transfusion was used safely as an effective alternative to hemodialysis in this case of severe infant salicylate poisoning...

..This rare case of EPO overdose highlights the complications of essential erythrocytosis, with central nervous system, peripheral, and presumed mesenteric ischemia...

..Health education theory using the social-cognitive theory provides a framework for developing future poison prevention programs to address identified issues with parents of young children...

..It has rarely been associated with the development of a progressive spongiform leukoencephalopathy...

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..CONCLUSIONS: The risks of this procedure are great and further studies should assess its safety and the novel use of naltrexone...