P Michael Ho

....

..Prior mechanistic studies reported that omeprazole decreases the platelet inhibitory effects of clopidogrel, yet the clinical significance of these findings is not clear...

..Little is known about the effect of nonadherence among patients with coronary artery disease (CAD) on a broad spectrum of outcomes including cardiovascular mortality, cardiovascular hospitalizations, and revascularization procedures...

..Our goal was to assess the prevalence of the failure to identify high-risk ECG findings in ED patients with AMI and to determine whether this failure is associated with lower-quality care...

..The frequency with which patients delay filling a clopidogrel prescription after DES implantation and the association of this delay with adverse outcomes is unknown...

..However, clopidogrel has historically been underused in this population. We evaluated contemporary rates of its use and evaluated associated factors, with a particular focus on hospital quality of myocardial infarction (MI) care...

..Our objective was to identify risk factors for development of incident CKD and decline in estimated GFR (eGFR) in hypertensive patients...

..We attempted to develop clinical prediction rules for adherence with antihypertensive medications in 2 healthcare delivery systems...

..Little is known about the association between clopidogrel use and long-term outcomes after stent implantation for acute coronary syndromes (ACS) in clinical practice...

..Little is known about the competing risk of bleeding from clopidogrel in "real world" clinical practice...

..Early outpatient follow-up after acute myocardial infarction (AMI) is recommended in guidelines, but its relationship with the use of evidence-based therapies is unknown...

..However, longitudinal studies evaluating these relationships and outcomes are limited...

..However, whether impaired HRR is associated with incident AF is unknown. We studied the association of impaired HRR with the development of incident AF, after controlling for demographic and clinical confounders...

..However, little is known about their prognostic use in combination and in addition to the Duke Treadmill Score (DTS)...

..A prior study from the Veterans Health Administration found a clustering of cardiovascular events after clopidogrel cessation. We sought to confirm and expand these findings...

..To assess the association between impaired chronotropic response (CR) and adverse events among patients with diabetes referred for exercise treadmill testing (ETT)...

..Despite the importance of blood pressure (BP) control in secondary prevention, a significant proportion of patients with coronary disease have uncontrolled BP...

..We tested the hypothesis that SMI is associated with higher one-year mortality following ACS hospitalization...

..Older age is a risk factor for higher mortality after acute myocardial infarction (AMI), but the association with health status outcomes is largely unexplored...

..Little is known about the use of such medications and their effects on outcomes in clinical practice...

....

..Preoperative patient self-report of health status may be particularly useful in refining risk stratification and informing decision-making before and following cardiac surgery in older patients...

....

..Limited literature exists on the association between medication adherence and outcomes among patients with heart failure...

..The objective of this research was to use adjusted Kaplan-Meier estimates and modified log-rank and Wilcoxon tests to examine the effect of a treatment that varies over time in an observational study...

..It is unknown whether patients are at increased short-term risk for adverse events following clopidogrel cessation...

..Our objective was to determine the prognostic importance of exercise capacity for nonfatal cardiac events in a clinical population...

..Clinical practice guidelines recommend multiple cardioprotective medications to reduce recurrent events. We evaluated the association between cardioprotective medication adherence and mortality among patients with diabetes and IHD...

..To evaluate whether systolic blood pressure (SBP) control is maintained following participation in a multimodal hypertension intervention...

....

..Eradication of angina is a primary goal of care after myocardial infarction (MI). However, the prevalence of angina 1 year after MI and factors associated with it are unknown...

..The impact of inpatient and follow-up cardiology care on patient outcomes after acute coronary syndrome (ACS) hospital discharge is unknown...

..Medication nonadherence may reduce the effectiveness of therapies. To our knowledge, the association between medication nonadherence and mortality remains unexplored outside the context of clinical trials...

..The objective of this study was to determine the importance of chest pain during ETT in predicting future nonfatal cardiac hospitalizations...

....

..Few interventions have specifically targeted this high-risk patient population to improve medication adherence. We hypothesize that a multifaceted patient-centered intervention could improve adherence to cardioprotective medications...

..However, no trial has assessed the comparative effectiveness of 2nd-line therapy in patients whose BP was not controlled with a thiazide diuretic...

..Little is known about the determinants of health-related quality of life after coronary artery bypass surgery. We determined the predictors of overall physical and mental health status 6 months after the operation...

..Therefore, we compared rates of secondary prevention medication prescription between patients with nonobstructive and obstructive CAD...

..In the randomized study, the intervention resulted in clinically significant decreases in BP...

..This study aims to investigate this association, and to uncover possible explanations for the lack of consensus across prior studies...

..Despite its importance, nonadherence remains a significant problem among this population, and a variety of studies have sought to determine its prevalence, contributing factors, and interventions for improvement...

..Our objectives were to identify patient-related risk factors, processes of care, and the occurrence of any perioperative complications associated with cognitive decline...

..We will also offer our view on the current state and future directions of HRQL assessment and use...

..We assessed the independent relationship between age and the quality of medical care provided to patients presenting to the emergency department (ED) with acute myocardial infarction...

..Although there may be challenges to achieving the vision of home-based disease management, there are tremendous potential benefits of such an approach for reducing the global burden of cardiovascular disease...

....

..We sought to determine whether the absence of supplemental Medicare coverage is associated with increased delay in seeking care for acute myocardial infarction...