Research Topics
| RICHARD ZARBOSummaryAffiliation: Henry Ford Hospital Country: USA Publications
Research Grants
| Collaborators
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Detail Information
Publications
Allelic loss and tumor pathology in head and neck squamous cell carcinomaBenjamin A Rybicki
Department of Biostatistics and Research Epidemiology, Henry Ford Health System, Detroit, Michigan 48202, USA
Mod Pathol 16:970-9. 2003..2 (P =.015). Our results suggest that genes involved in tumor suppression and oncogenesis can potentially be classified based on specific pathologic events in head and neck squamous cell carcinogenesis that they modify...- Monitoring anatomic pathology practice through quality assurance measuresR J Zarbo
Department of Pathology, Henry Ford Hospital, Henry Ford Health Sciences Center Case Western Reserve University, Detroit, Michigan, USA
Clin Lab Med 19:713-42, v. 1999..Comparative data quantifying performance deficiencies and opportunities for practice improvement are also identified... - Conference summary, Strategic Science symposium. Her-2/neu testing of breast cancer patients in clinical practiceRichard J Zarbo
Department of Pathology, Henry Ford Hospital and Medical Group, Detroit, Mich 48202, USA
Arch Pathol Lab Med 127:549-53. 2003..This dilemma becomes especially acute when the assay is the sole determinant for selection of a specific therapy... - Malignant ameloblastoma, spindle cell variantRichard J Zarbo
Department of Pathology, Henry Ford Hospital, Detroit, MI 48202, USA
Arch Pathol Lab Med 127:352-5. 2003.... - Customer satisfaction in anatomic pathology. A College of American Pathologists Q-Probes study of 3065 physician surveys from 94 laboratoriesRichard J Zarbo
Department of Pathology, Henry Ford Hospital, Detroit, Mich 48202, USA
Arch Pathol Lab Med 127:23-9. 2003..To our knowledge, this is the first customer satisfaction survey of anatomic pathology services to provide a standardized tool and benchmarks for subsequent measures of satisfaction... - Determining customer satisfaction in anatomic pathologyRichard J Zarbo
Department of Pathology, Henry Ford Hospital, Detroit, MI 48202, USA
Arch Pathol Lab Med 130:645-9. 2006..Pathologists, therefore, must often design their own local assessment tools to determine physician satisfaction in anatomic pathology... - Q-tracks: a College of American Pathologists program of continuous laboratory monitoring and longitudinal trackingRichard J Zarbo
Department of Pathology, Henry Ford Hospital, Detroit, Mich 48202, USA
Arch Pathol Lab Med 126:1036-44. 2002.... - Salivary gland neoplasia: a review for the practicing pathologistRichard J Zarbo
Department of Pathology, Henry Ford Hospital, Detroit, Michigan 48202, USA
Mod Pathol 15:298-323. 2002 - Use of microsatellite analysis in detection of tumor lineage as a cause of death in a liver transplant patientMilena Cankovic
Department of Pathology, Henry Ford Hospital, Detroit, Michigan 48202, USA
Arch Pathol Lab Med 130:529-32. 2006..The pattern of microsatellite allelic expression strongly suggested that the melanoma detected at autopsy originated from the transplanted liver... - The value of monitoring frozen section-permanent section correlation data over timeStephen S Raab
Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15232, USA
Arch Pathol Lab Med 130:337-42. 2006..The effectiveness of the long-term monitoring of errors detected by frozen section-permanent section correlation is unknown... - Detection of non-maternal components of gestational choriocarcinoma by PCR-based microsatellite DNA assayMilena Cankovic
Henry Ford Hospital, Detroit, MI 48202, USA
Gynecol Oncol 103:614-7. 2006..Our objective was to develop a convenient, fast, and reliable assay that would, using only patient tissue, allow separation of gestational from non-gestational choriocarcinomas... - Failure to detect human herpes simplex virus, cytomegalovirus, and Epstein-Barr virus viral genomes in giant cell arteritis biopsy specimens by real-time quantitative polymerase chain reactionMilena Cankovic
Department of Pathology, Henry Ford Hospital, Detroit, MI 48202, USA
Cardiovasc Pathol 15:280-6. 2006..Our study failed to confirm an association between HSV1 and GCA, revealing no viral genome in 35 biopsy specimens of histologically positive temporal arteries... - Angioimmunoblastic T-cell lymphoma with supervening Epstein-Barr virus-associated large B-cell lymphomaRobert C Hawley
Department of Pathology, Henry Ford Hospital, 2799 W Grand Blvd, Detroit, MI 48202, USA
Arch Pathol Lab Med 130:1707-11. 2006.... - A simplified laboratory validated assay for MGMT promoter hypermethylation analysis of glioma specimens from formalin-fixed paraffin-embedded tissueMilena Cankovic
Department of Pathology, Henry Ford Hospital, Detroit, MI 48202, USA
Lab Invest 87:392-7. 2007..The objective of this study was to develop a reliable, clinically validated assay for detection of epigenetic silencing of the MGMT gene using formalin-fixed, paraffin-embedded brain tumor resections and methylation-specific PCR... - Clinical laboratory specimen rejection--association with the site of patient care and patients' characteristics: findings from a single health care organizationAzadeh Stark
Department of Pathology and Laboratory Medicine, K 6, Henry Ford Health System Main Hospital, 2799 W Grand Blvd, Detroit, MI 48202, USA
Arch Pathol Lab Med 131:588-92. 2007..83%. Because the performance of the laboratory, rather than errors, has been the focus, reasons for specimen rejection or demographic characteristics of individuals at risk for specimens of poor quality may not be fully understood... - The Henry Ford Production System: measures of process defects and waste in surgical pathology as a basis for quality improvement initiativesRichard J Zarbo
Pathology and Laboratory Medicine, Henry Ford Health System, Detroit, MI 48202, USA
Am J Clin Pathol 128:423-9. 2007..This knowledge formed the structure for effective changes to strive toward a zero-defect performance goal... - Frequency and outcome of cervical cancer prevention failures in the United StatesStephen S Raab
Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, and Western Pennsylvania Hospital 15232, USA
Am J Clin Pathol 128:817-24. 2007..We conclude that cervical cancer prevention practices are remarkably successful in preventing squamous cancers, although a high frequency of failures results in low-impact negative outcomes... - The Henry ford production system: effective reduction of process defects and waste in surgical pathologyRichard J Zarbo
Pathology and Laboratory Medicine, Henry Ford Health System, Detroit, MI 48202, USA
Am J Clin Pathol 128:1015-22. 2007..We share the key improvements implemented that were responsible for the overall success in reducing waste and re-work in the broad spectrum of surgical pathology processes... - Anatomic pathology databases and patient safetyStephen S Raab
Department of Pathology and Laboratory Medicine, University of Pittsburgh Medical Center Shadyside, Pittsburgh, PA 15232, USA
Arch Pathol Lab Med 129:1246-51. 2005..The utility of anatomic pathology discrepancies has not been rigorously studied... - Error detection in anatomic pathologyRichard J Zarbo
Department of Pathology and Laboratory Medicine, Henry Ford Health System, Detroit, MI 48202, USA
Arch Pathol Lab Med 129:1237-45. 2005..In particular, the value of double-reading, case conferences, and consultations (the traditional triad of error control in anatomic pathology) awaits objective assessment... - Defining the role of myoepithelium in salivary gland neoplasiaAdnan T Savera
Department of Pathology, Henry Ford Hospital, Detroit, Michigan 48202, USA
Adv Anat Pathol 11:69-85. 2004..Here we discuss the role of neoplastic myoepithelium in the scope of salivary gland neoplasia and present this information from a practical diagnostic standpoint... - Primary salivary clear cell tumors--a diagnostic approach: a clinicopathologic and immunohistochemical study of 20 patients with clear cell carcinoma, clear cell myoepithelial carcinoma, and epithelial-myoepithelial carcinomaBeverly Wang
Lillian and Henry M. Stratton-Hans Popper Department of Pathology, The Mount Sinai School of Medicine, New York, NY 10021, USA
Arch Pathol Lab Med 126:676-85. 2002..The lack of myoepithelial differentiation in CCC is consistent with the concept that this tumor is histomorphogenically distinct from EMEC and that it is not merely a monomorphic variant... - Prognostic implications of loss of heterozygosity at 8p21 and 9p21 in head and neck squamous cell carcinomaSteven W Coon
Department of Biostatistics and Research Epidemiology, Henry Ford Health System, Detroit, MI 48202, USA
Int J Cancer 111:206-12. 2004..2 (relative risk = 5.96; p = 0.0003). Our results indicate that LOH at several chromosomal sites may offer additional independent prognostic information beyond traditional indicators such as tumor stage and age... - Morphologic criteria for the diagnosis of prostatic adenocarcinoma in needle biopsy specimens. A study of 250 consecutive cases in a routine surgical pathology practiceMurali Varma
Department of Pathology, Henry Ford Hospital, Detroit, Mich, USA
Arch Pathol Lab Med 126:554-61. 2002.... - Diagnostic value of HMB-45 and anti-Melan A staining of sentinel lymph nodes with isolated positive cellsMuhammad N Mahmood
Departments of Pathology, Henry Ford Hospital, Detroit, Michigan 48202, USA
Mod Pathol 15:1288-93. 2002..HMB-45 may not be a reliable marker for the detection of micro-metastasis of MM and requires correlation with other immunohistochemical markers, such as anti-Melan A antibody, to enhance specificity... - Human papillomavirus testing--are you ready for a new era in cervical cancer screening?Diane D Davey
Department of Pathology and Laboratory Medicine, University of Kentucky Medical Center, Lexington 40536 0298, USA
Arch Pathol Lab Med 127:927-9. 2003 - Anatomic pathology and patient safety: it's not an error: it's a diagnostic misadventure!Dana Marie Grzybicki
Am J Clin Pathol 129:167-8; author reply 169. 2008 - NF-kappaB in breast cancer cells promotes osteolytic bone metastasis by inducing osteoclastogenesis via GM-CSFBae Keun Park
Laboratory of Molecular Signaling and Apoptosis, Department of Biologic and Materials Sciences, University of Michigan, 1011 North University Avenue, Ann Arbor, Michigan 48109, USA
Nat Med 13:62-9. 2007.... - The diagnostic utility of p63, CK5/6, CK 7, and CK 20 in distinguishing primary cutaneous adnexal neoplasms from metastatic carcinomasHina S Qureshi
Department of Pathology, Henry Ford Hospital, Detroit, MI, USA
J Cutan Pathol 31:145-52. 2004.... - Use of a new method in reaching consensus on the cause of cytologic-histologic correlation discrepancyStephen S Raab
Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Am J Clin Pathol 126:836-42. 2006..Most discrepancies resulted from pathologists diagnosing noninterpretable samples. Pathologists who used the No-Blame Box showed significant agreement in the adjudication of discrepancy cause... - Use of physician extenders in surgical pathology practiceDana Marie Grzybicki
Department of Pathology and Laboratory Medicine, Allegheny General Hospital, Pittsburgh, PA, USA
Arch Pathol Lab Med 128:165-72. 2004..Use of a variety of nonphysician personnel for surgical pathology gross examination is generally known to be increasing, although detailed information regarding nonphysician use is currently unavailable... - The "Big Dog" effect: variability assessing the causes of error in diagnoses of patients with lung cancerStephen S Raab
Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
J Clin Oncol 24:2808-14. 2006..The frequency of diagnostic error in patients who have a lung mass and a pathology specimen is as high as 15%. This study examined the role of inter-pathologist agreement in identifying the cause of error in these patients... - The challenges of prostate cancer detection. Interview by Carren BerschJohn E Tomaszewski
MLO Med Lab Obs 36:26, 30-1. 2004 - Double slide viewing as a cytology quality improvement initiativeStephen S Raab
Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15232, and Henry Ford Health System, Detroit, MI, USA
Am J Clin Pathol 125:526-33. 2006..We conclude that double viewing detects errors in up to 1 of every 37 cases and that biases in the double-viewing process limit error detection... - Chondroid syringoma. Cytokeratin 20 immunolocalization of Merkel cells and reappraisal of apocrine folliculo-sebaceous differentiationMohamed E Salama
Department of Pathology, Henry Ford Hospital, Detroit, Mich 48202, USA
Arch Pathol Lab Med 128:986-90. 2004..To our knowledge, the presence of Merkel cells in CS, particularly in proliferative form, has not been described previously in the literature... - Clinical impact and frequency of anatomic pathology errors in cancer diagnosesStephen S Raab
Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15232, USA
Cancer 104:2205-13. 2005..To the authors' knowledge, the frequency and clinical impact of errors in the anatomic pathology diagnosis of cancer have been poorly characterized to date... 
Amended reports: development and validation of a taxonomy of defectsFrederick A Meier
Department of Pathology and Laboratory Medicine, Henry Ford Hospital, Detroit, MI 48202, USA
Am J Clin Pathol 130:238-46. 2008..Conference review revealed 40% to 80% of misinterpretations. This taxonomy produced excellent reproducibility and good agreement across institutions...
Research Grants
- TISSUE PROCUREMENT CORE FACILITY AT JOSEPHINE FORD CANCERICHARD ZARBO; Fiscal Year: 2004....