L Keoki Williams

Summary

Affiliation: Henry Ford Hospital
Country: USA

Publications

  1. ncbi request reprint Differences in the reporting of care-related patient injuries to existing reporting systems
    L Keoki Williams
    Department of Internal Medicine, Division of General Medicine, Henry Ford Hospital, Detroit, USA
    Jt Comm J Qual Saf 29:460-7. 2003
  2. pmc Quantifying the proportion of severe asthma exacerbations attributable to inhaled corticosteroid nonadherence
    L Keoki Williams
    Center for Health Services Research, Henry Ford Health System, Detroit, MI 48202, USA
    J Allergy Clin Immunol 128:1185-1191.e2. 2011
  3. pmc A simulation model approach to analysis of the business case for eliminating health care disparities
    David R Nerenz
    Center for Health Services Research, Henry Ford Health System, Detroit, MI, USA
    BMC Med Res Methodol 11:31. 2011
  4. pmc The role of endotoxin and its receptors in allergic disease
    L Keoki Williams
    Department of Internal Medicine, Henry Ford Health System, Detroit, Michigan 48202, USA
    Ann Allergy Asthma Immunol 94:323-32. 2005
  5. ncbi request reprint Race-ethnicity, crime, and other factors associated with adherence to inhaled corticosteroids
    L Keoki Williams
    Department of Internal Medicine, Henry Ford Health System, Detroit, MI 48202, USA
    J Allergy Clin Immunol 119:168-75. 2007
  6. ncbi request reprint Patients with asthma who do not fill their inhaled corticosteroids: a study of primary nonadherence
    L Keoki Williams
    Department of Internal Medicine, Henry Ford Hospital, Detroit, MI, USA
    J Allergy Clin Immunol 120:1153-9. 2007
  7. pmc Gene-environment interactions between CD14 C-260T and endotoxin exposure on Foxp3+ and Foxp3- CD4+ lymphocyte numbers and total serum IgE levels in early childhood
    L Keoki Williams
    Department of Internal Medicine, Henry Ford Health System, Detroit, Michigan 48202, USA
    Ann Allergy Asthma Immunol 100:128-36. 2008
  8. ncbi request reprint Timing and intensity of early fevers and the development of allergies and asthma
    L Keoki Williams
    Department of Internal Medicine, Center for Health Services Research, Henry Ford Health System, Detroit, MI 48202, USA
    J Allergy Clin Immunol 116:102-8. 2005
  9. ncbi request reprint Gene-environment interactions with CD14 C-260T and their relationship to total serum IgE levels in adults
    L Keoki Williams
    Department of Internal Medicine, Henry Ford Health System, Detroit, MI 48202, USA
    J Allergy Clin Immunol 118:851-7. 2006
  10. ncbi request reprint Relationship between adherence to inhaled corticosteroids and poor outcomes among adults with asthma
    L Keoki Williams
    Department of Internal Medicine, Henry Ford Health System, Detoit, MI 48202, USA
    J Allergy Clin Immunol 114:1288-93. 2004

Detail Information

Publications57

  1. ncbi request reprint Differences in the reporting of care-related patient injuries to existing reporting systems
    L Keoki Williams
    Department of Internal Medicine, Division of General Medicine, Henry Ford Hospital, Detroit, USA
    Jt Comm J Qual Saf 29:460-7. 2003
    ..This study compared the number of care-related injuries reported to the Joint Commission on Accreditation of Healthcare Organizations (JCAHO) with the number reported to 15 mandatory-reporting states...
  2. pmc Quantifying the proportion of severe asthma exacerbations attributable to inhaled corticosteroid nonadherence
    L Keoki Williams
    Center for Health Services Research, Henry Ford Health System, Detroit, MI 48202, USA
    J Allergy Clin Immunol 128:1185-1191.e2. 2011
    ..Asthma is an inflammatory condition often punctuated by episodic symptomatic worsening, and accordingly, patients with asthma might have waxing and waning adherence to controller therapy...
  3. pmc A simulation model approach to analysis of the business case for eliminating health care disparities
    David R Nerenz
    Center for Health Services Research, Henry Ford Health System, Detroit, MI, USA
    BMC Med Res Methodol 11:31. 2011
    ..A need exists to develop a compelling "business case" from the employer perspective to put, and keep, the issue of racial/ethnic disparities in health care on the quality improvement agenda for health plans and providers...
  4. pmc The role of endotoxin and its receptors in allergic disease
    L Keoki Williams
    Department of Internal Medicine, Henry Ford Health System, Detroit, Michigan 48202, USA
    Ann Allergy Asthma Immunol 94:323-32. 2005
    ..To summarize the existing literature on the association of endotoxin with respiratory diseases and allergic sensitization and to review the potentially modifying effects of endotoxin receptor polymorphisms...
  5. ncbi request reprint Race-ethnicity, crime, and other factors associated with adherence to inhaled corticosteroids
    L Keoki Williams
    Department of Internal Medicine, Henry Ford Health System, Detroit, MI 48202, USA
    J Allergy Clin Immunol 119:168-75. 2007
    ..Environmental stressors, such as crime exposure, which has been associated with asthma morbidity, might also predict ICS adherence...
  6. ncbi request reprint Patients with asthma who do not fill their inhaled corticosteroids: a study of primary nonadherence
    L Keoki Williams
    Department of Internal Medicine, Henry Ford Hospital, Detroit, MI, USA
    J Allergy Clin Immunol 120:1153-9. 2007
    ..Adherence to inhaled corticosteroids (ICSs) is known to be poor among patients with asthma; however, little is known about patients who do not fill their ICS prescriptions (ie, primary nonadherence)...
  7. pmc Gene-environment interactions between CD14 C-260T and endotoxin exposure on Foxp3+ and Foxp3- CD4+ lymphocyte numbers and total serum IgE levels in early childhood
    L Keoki Williams
    Department of Internal Medicine, Henry Ford Health System, Detroit, Michigan 48202, USA
    Ann Allergy Asthma Immunol 100:128-36. 2008
    ..Previously, we described gene-environment interactions between the endotoxin receptor polymorphism C-260T of the CD14 gene and endotoxin exposure on total serum IgE level; however, the mechanism of this interaction is not known...
  8. ncbi request reprint Timing and intensity of early fevers and the development of allergies and asthma
    L Keoki Williams
    Department of Internal Medicine, Center for Health Services Research, Henry Ford Health System, Detroit, MI 48202, USA
    J Allergy Clin Immunol 116:102-8. 2005
    ..Early childhood fevers appear to protect against later allergies and asthma. What is not known is the time in which fevers exert this effect and whether the degree of temperature increase is important...
  9. ncbi request reprint Gene-environment interactions with CD14 C-260T and their relationship to total serum IgE levels in adults
    L Keoki Williams
    Department of Internal Medicine, Henry Ford Health System, Detroit, MI 48202, USA
    J Allergy Clin Immunol 118:851-7. 2006
    ..Furred pets might also influence IgE levels through their effects on endotoxin levels. However, how these factors interact to influence total IgE levels is not well known, especially in adults...
  10. ncbi request reprint Relationship between adherence to inhaled corticosteroids and poor outcomes among adults with asthma
    L Keoki Williams
    Department of Internal Medicine, Henry Ford Health System, Detoit, MI 48202, USA
    J Allergy Clin Immunol 114:1288-93. 2004
    ..However, overall adherence is poor among patients with asthma. Objective To estimate the proportion of poor asthma-related outcomes attributable to ICS nonadherence...
  11. pmc A cluster-randomized trial to provide clinicians inhaled corticosteroid adherence information for their patients with asthma
    L Keoki Williams
    Center for Health Services Research, Henry Ford Health System, Detroit, MI 48202, USA
    J Allergy Clin Immunol 126:225-31, 231.e1-4. 2010
    ..Inhaled corticosteroid (ICS) nonadherence is common among patients with asthma; however, interventions to improve adherence have often been complex and not easily applied to large patient populations...
  12. pmc Differences in allergic sensitization by self-reported race and genetic ancestry
    James J Yang
    Department of Biostatistics and Research Epidemiology, Henry Ford Health System, Detroit, MI 48202, USA
    J Allergy Clin Immunol 122:820-827.e9. 2008
    ..Many allergic conditions occur more frequently in African American patients when compared with white patients; however, it is not known whether this represents genetic predisposition or disparate environmental exposures...
  13. pmc Genetic ancestry and its association with asthma exacerbations among African American subjects with asthma
    Jennifer A Rumpel
    Department of Internal Medicine, Henry Ford Health System, Detroit, MI, USA
    J Allergy Clin Immunol 130:1302-6. 2012
    ..It is unclear whether this increased risk solely represents differences in environmental exposures and health care or whether there is a predisposing genetic component...
  14. pmc Race-ethnic differences in factors associated with inhaled steroid adherence among adults with asthma
    Karen Wells
    Department of Biostatistics and Research Epidemiology, Henry Ford Hospital, Detroit, MI 48202, USA
    Am J Respir Crit Care Med 178:1194-201. 2008
    ..Adherence to inhaled corticosteroid (ICS) medication is known to be low overall, but tends to be lower among African-American patients when compared with white patients...
  15. ncbi request reprint Antibiotic exposure in early infancy and risk for childhood atopy
    Christine Cole Johnson
    Department of Biostatistics and Research Epidemiology, Henry Ford Health System, 1 Ford Place 5C, Detroit, MI 48202, USA
    J Allergy Clin Immunol 115:1218-24. 2005
    ..The increase in pediatric allergy and asthma parallels the increase in use of antibiotics. Antibiotics disturb the flora of the gastrointestinal tract, possibly perturbing the developing immune system...
  16. ncbi request reprint Breastfeeding history and childhood allergic status in a prospective birth cohort
    Ganesa Wegienka
    Department of Biostatistics and Research Epidemiology, Henry Ford Health System, Detroit, Michigan 48202, USA
    Ann Allergy Asthma Immunol 97:78-83. 2006
    ..Breastfeeding provides the best possible nutrition for newborns, but its role in the development of allergies is complex...
  17. pmc Identifying students with self-report of asthma and respiratory symptoms in an urban, high school setting
    Christine L M Joseph
    Department of Biostatistics and Research Epidemiology, Detroit, MI 48202, USA
    J Urban Health 84:60-9. 2007
    ..Itemized expenses are presented to facilitate modifications to reduce costs. This information may benefit providers, researchers, or administrators targeting similar populations...
  18. pmc The relationship between combination inhaled corticosteroid and long-acting β-agonist use and severe asthma exacerbations in a diverse population
    Karen E Wells
    Department of Public Health Sciences, Henry Ford Health System, Detroit, MI 48202, USA
    J Allergy Clin Immunol 129:1274-1279.e2. 2012
    ..Safety concerns surround the use of long-acting β-agonists (LABAs) for the treatment of asthma, even in combination with inhaled corticosteroids (ICSs) and particularly in high-risk subgroups...
  19. pmc Dual-specificity phosphatase 1 as a pharmacogenetic modifier of inhaled steroid response among asthmatic patients
    Ying Jin
    Center for Health Services Research, Henry Ford Health System, Detroit, Mich Wayne State University School of Medicine, Detroit, Mich 48202, USA
    J Allergy Clin Immunol 126:618-25.e1-2. 2010
    ..Dual-specificity phosphatase 1 (DUSP1) appears to mediate the anti-inflammatory action of corticosteroids...
  20. pmc Relationship between thiazolidinedione use and cardiovascular outcomes and all-cause mortality among patients with diabetes: a time-updated propensity analysis
    Zeina A Habib
    Department of Internal Medicine, Henry Ford Hospital, Detroit, MI 48202, USA
    Pharmacoepidemiol Drug Saf 18:437-47. 2009
    ....
  21. pmc Thiazolidinedione use and the longitudinal risk of fractures in patients with type 2 diabetes mellitus
    Zeina A Habib
    Center for Health Services Research, Henry Ford Health System, 1 Ford Place, 3A Center for Health Services Research, Detroit, Michigan 48202, USA
    J Clin Endocrinol Metab 95:592-600. 2010
    ..Thiazolidinedione (TZD) use has recently been associated with an increased risk of fractures...
  22. pmc Comparison of renal predictors for in-hospital and postdischarge mortality after hospitalized heart failure
    Gurjit Singh
    Heart and Vascular Institute, Henry Ford Hospital, Detroit, Michigan 48202, USA
    J Cardiovasc Med (Hagerstown) 13:246-53. 2012
    ..Abnormal baseline and acutely worsening renal function (WRF) during heart failure hospitalization are associated with worse outcomes. However, which renal criterion is most predictive of in-hospital and postdischarge mortality is uncertain...
  23. pmc Relationship between recent short-acting beta-agonist use and subsequent asthma exacerbations
    Jason Paris
    Department of Internal Medicine, Henry Ford Hospital, Detroit, Michigan 48202, USA
    Ann Allergy Asthma Immunol 101:482-7. 2008
    ..US national guidelines recommend assessing short-acting beta-agonist (SABA) medication use as a marker of asthma severity and control. However, the relationship between recent SABA use and asthma exacerbations is not currently known...
  24. pmc Multicenter cluster-randomized trial of a multifactorial intervention to improve antihypertensive medication adherence and blood pressure control among patients at high cardiovascular risk (the COM99 study)
    Manel Pladevall
    Center for Health Services Research, Henry Ford Hospital, One Ford Place 3A, Detroit, MI, USA
    Circulation 122:1183-91. 2010
    ..This study assessed the effectiveness of a multifactorial intervention to improve both medication adherence and blood pressure control and to reduce cardiovascular events...
  25. ncbi request reprint Trends in lipid management among patients with diabetes
    Kaan Tunceli
    Center for Health Services Research, Henry Ford Health System, Detroit, Michigan 48202, USA
    Endocr Pract 12:380-7. 2006
    ..To examine trends in lipid management (cholesterol testing, treatment, and goal attainment) among patients with diabetes and to analyze the factors associated with initiation of lipid-lowering therapy...
  26. ncbi request reprint Long-term effects of obesity on employment and work limitations among U.S. Adults, 1986 to 1999
    Kaan Tunceli
    Center for Health Services Research, Henry Ford Health System, Detroit, Michigan, USA
    Obesity (Silver Spring) 14:1637-46. 2006
    ..To determine the relationships between BMI and workforce participation and the presence of work limitations in a U.S. working-age population...
  27. pmc Effect of ezetimibe on major atherosclerotic disease events and all-cause mortality
    Sami Hayek
    Department of Internal Medicine, Henry Ford Health System, Detroit, Michigan, USA
    Am J Cardiol 111:532-9. 2013
    ..In conclusion, ezetimibe appeared to have a protective effect on major AD events and all-cause death that was not significantly different from that observed for statin use...
  28. pmc Association of β-blocker exposure with outcomes in heart failure differs between African American and white patients
    David E Lanfear
    Heart and Vascular Institute, Henry Ford Hospital, Detroit, MI 48202, USA
    Circ Heart Fail 5:202-8. 2012
    ..Blockers (BB) are a mainstay of heart failure (HF) treatment, yet there are inconclusive data regarding their efficacy in African American individuals...
  29. ncbi request reprint The relationship between early fever and allergic sensitization at age 6 to 7 years
    L Keoki Williams
    Division of General Medicine, Department of Internal Medicine, Detroit, Mich, USA
    J Allergy Clin Immunol 113:291-6. 2004
    ..The hygiene hypothesis suggests that early infections might protect against later allergic sensitization...
  30. pmc Comparison of β-blocker effectiveness in heart failure patients with preserved ejection fraction versus those with reduced ejection fraction
    Mostafa El-Refai
    Department of Internal Medicine, Henry Ford Hospital, Detroit, Michigan 48202, USA
    J Card Fail 19:73-9. 2013
    ..The aim of this study was to compare the benefit of beta-blockers (BB) in heart failure (HF) with preserved versus reduced ejection fraction (EF)...
  31. pmc Examining the relationship between depression and asthma exacerbations in a prospective follow-up study
    Brian K Ahmedani
    Center for Health Policy and Health Services Research, Henry Ford Health System, Detroit, MI 48202, USA
    Psychosom Med 75:305-10. 2013
    ..The aim is to investigate whether depression increases exacerbations among patients with asthma...
  32. pmc Real-world effects of once vs greater daily inhaled corticosteroid dosing on medication adherence
    Karen E Wells
    Department of Public Health Sciences, Henry Ford Health System, Detroit, Michigan, USA
    Ann Allergy Asthma Immunol 111:216-20. 2013
    ..Simplifying dosing regimens for some chronic disease conditions has resulted in better adherence; however, little is known regarding the effect of ICS dosing on adherence for the treatment of asthma...
  33. pmc A meta-analysis of genome-wide association studies for serum total IgE in diverse study populations
    Albert M Levin
    Department of Public Health Sciences, Henry Ford Health System, Detroit, MI, USA
    J Allergy Clin Immunol 131:1176-84. 2013
    ..IgE is both a marker and mediator of allergic inflammation. Despite reported differences in serum total IgE levels by race-ethnicity, African American and Latino subjects have not been well represented in genetic studies of total IgE...
  34. pmc Applying epidemiologic concepts of primary, secondary, and tertiary prevention to the elimination of racial disparities in asthma
    Christine L M Joseph
    Department of Biostatistics and Research Epidemiology, Henry Ford Health System, Detroit, MI 48202, USA
    J Allergy Clin Immunol 117:233-40; quiz 241-2. 2006
    ..Once causative factors at each level of disease prevention are understood, this knowledge can be translated into clinical practice and public health policy...
  35. pmc Asthma medication adherence: the role of God and other health locus of control factors
    Brian K Ahmedani
    Center for Health Policy and Health Services Research, Henry Ford Health System, Detroit, Michigan 48202, USA
    Ann Allergy Asthma Immunol 110:75-9.e2. 2013
    ..Although several predictors of non-adherence have been assessed, more research is needed on patients' beliefs about God and how these relate to medication use...
  36. ncbi request reprint The impact of diabetes on employment and work productivity
    Kaan Tunceli
    Center for Health Services Research, Henry Ford Health System, Detroit, MI 48202, USA
    Diabetes Care 28:2662-7. 2005
    ..The purpose of this study was to longitudinally examine the effect of diabetes on labor market outcomes...
  37. ncbi request reprint Improving asthma care through recertification: a cluster randomized trial
    Jan Simpkins
    Center for Health Services Research, Henry Ford Hospital, One Ford Place, Detroit, MI 48202, USA
    Arch Intern Med 167:2240-8. 2007
    ..We assessed whether completing an asthma-specific PIM resulted in improved patient outcomes...
  38. pmc Clinical outcomes and adherence to medications measured by claims data in patients with diabetes
    Manel Pladevall
    Center for Health Services Research, Henry Ford Health System, One Ford Place, Suite 3A, Detroit, Michigan 48202, USA
    Diabetes Care 27:2800-5. 2004
    ..The present study was conducted to determine whether pharmacy claims-based measures of medication adherence are associated with clinical outcomes in patients with diabetes...
  39. ncbi request reprint Patient-physician colorectal cancer screening discussions and screening use
    Jennifer Elston Lafata
    Center for Health Services Research, Henry Ford Health System, Detroit, Michigan 48202, USA
    Am J Prev Med 31:202-9. 2006
    ..Analyses conducted in 2004-2005 of patient-physician CRC screening discussion content and its association with screening use are described...
  40. pmc Association of genetic variation with gene expression and protein abundance within the natriuretic peptide pathway
    David E Lanfear
    Department of Internal Medicine, Division of Cardiology, Henry Ford Heart and Vascular Institute, Henry Ford Hospital, Detroit, MI, USA
    J Cardiovasc Transl Res 6:826-33. 2013
    ..05), but not RNA quantity. RNA and protein quantity correlated poorly with each other. The PC analysis showed only NPR2 as significant. Assessment of the clinical impact of NPR2 genetic variation is needed. ..
  41. ncbi request reprint Policies and events affecting prescription opioid use for non-cancer pain among an insured patient population
    Brian K Ahmedani
    Center for Health Policy and Health Services Research, Henry Ford Health System, Detroit, MI Department of Public Health Sciences, Henry Ford Health System, Detroit, MI Department of Internal Medicine, Henry Ford Health System, Detroit, MI
    Pain Physician 17:205-16. 2014
    ..Rising prescription opioid use and abuse have prompted widespread concern. However, to date there have been few rigorous investigations into the policies and events which may have contributed to these trends...
  42. pmc Comparing methods for identifying patients with heart failure using electronic data sources
    Fadi Alqaisi
    Henry Ford Heart and Vascular Institute, Henry Ford Hospital, 2799 W, Grand Blvd, Detroit, MI 48202, USA
    BMC Health Serv Res 9:237. 2009
    ..Yet, there are few comparisons of the various claims data criteria (also known as claims signatures) for identifying HF patients. We compared various HF claim signatures to assess their relative accuracy...
  43. ncbi request reprint Colorectal carcinoma screening procedure use among primary care patients
    Jennifer Elston Lafata
    Center for Health Services Research, Henry Ford Health System, Detroit, Michigan 48202, USA
    Cancer 104:1356-61. 2005
    ..The authors estimated the annual and 5-year colorectal carcinoma screening procedure use among a cohort of primary care patients and evaluated the correlation between patient characteristics and the use of screening procedures...
  44. ncbi request reprint Two ATS recommended protocols for administration of methacholine are not equal
    Robert R Burke
    Henry Ford Health System, Division of Pulmonary and Critical Care Medicine, Detroit, Michigan 48202, USA
    J Asthma 46:740-4. 2009
    ..Recent data has disputed this assertion. We examined the differences in the diagnosis of asthma using these two methods...
  45. pmc Relation of worsened renal function during hospitalization for heart failure to long-term outcomes and rehospitalization
    David E Lanfear
    Heart and Vascular Institute, Henry Ford Hospital, Detroit, Michigan, USA
    Am J Cardiol 107:74-8. 2011
    ..09, 95% CI 0.96 to 1.24). In conclusion, in patients surviving hospitalization for HF, WRF was associated with increased long-term mortality and rehospitalization, particularly if renal function did not recover by the time of discharge...
  46. doi request reprint Long-term projections for diabetes-related work loss and limitations among U.S. adults
    Kaan Tunceli
    Center for Health Services Research, Henry Ford Hospital, Detroit, MI 48202, USA
    Diabetes Res Clin Pract 83:e23-5. 2009
    ..In the year 2050 an estimated 1.46 million U.S. adults will not be working; 597,000 will be work disabled; and 780,000 will have work limitations as a result of diabetes...
  47. pmc Factors predicting inhaled corticosteroid responsiveness in African American patients with asthma
    Wendy Gould
    Department of Internal Medicine, Henry Ford Health System, Detroit, MI 48202, USA
    J Allergy Clin Immunol 126:1131-8. 2010
    ..African American patients disproportionately experience uncontrolled asthma. Treatment with an inhaled corticosteroid (ICS) is considered first-line therapy for persistent asthma...
  48. ncbi request reprint The association between leptin and left ventricular hypertrophy: a population-based cross-sectional study
    Manel Pladevall
    Center for Health Services Research, Henry Ford Health System, Detroit, Michigan, USA corrected
    J Hypertens 21:1467-73. 2003
    ..This study examines whether leptin levels, independent of body mass and insulin resistance, are a risk factor for hypertension and left ventricular hypertrophy...
  49. ncbi request reprint Environmental epidemiology of pediatric asthma and allergy
    Christine Cole Johnson
    Department of Biostatistics and Research Epidemiology, Henry Ford Health System, Detroit, MI, USA
    Epidemiol Rev 24:154-75. 2002
  50. ncbi request reprint A single factor underlies the metabolic syndrome: a confirmatory factor analysis
    Manel Pladevall
    Henry Ford Health System, Center for Health Services Research, One Ford Place, Suite 3A, Detroit, Michigan 48202, USA
    Diabetes Care 29:113-22. 2006
    ..Confirmatory factor analysis (CFA) was used to test the hypothesis that the components of the metabolic syndrome are manifestations of a single common factor...
  51. ncbi request reprint Inhaled corticosteroids and augmented bronchodilator responsiveness in Latino and African American asthmatic patients
    Mariam Naqvi
    University of California, San Francisco, California 94143 2911, USA
    Ann Allergy Asthma Immunol 100:551-7. 2008
    ....
  52. ncbi request reprint The relationship between seroatopy and symptoms of either allergic rhinitis or asthma
    Christina M Abraham
    Section of Allergy and Immunology, Medical College of Georgia, Augusta, GA 30912, USA
    J Allergy Clin Immunol 119:1099-104. 2007
    ..Epidemiologic data on allergic rhinitis and asthma are frequently based on self-reported symptoms...
  53. ncbi request reprint Relationship between extremely low total serum IgE levels and rhinosinusitis
    Todd A Levin
    Section of Allergy and Immunology, Medical College of Georgia, Augusta, Georgia 30912, USA
    Ann Allergy Asthma Immunol 97:650-2. 2006
    ..The few studies examining clinical manifestations in adults with serum IgE levels less than 2.0 IU/mL provide conflicting information...
  54. pmc An african-specific functional polymorphism in KCNMB1 shows sex-specific association with asthma severity
    Max A Seibold
    Department of Medicine, University of California San Francisco, San Francisco, CA 94143 2911, USA
    Hum Mol Genet 17:2681-90. 2008
    ..Female asthmatics may be insulated from the deleterious effects of the 818T allele by estrogen-mediated upregulation in BK channel activity...
  55. ncbi request reprint Adherence analysis using visual analog scale versus claims-based estimation
    David P Nau
    College of Pharmacy, University of Kentucky, Lexington, KY 40536, USA
    Ann Pharmacother 41:1792-7. 2007
    ..Although visual analog scales (VAS) have been used frequently in outcomes research, there is little evidence regarding the validity of this scale for measuring medication adherence...
  56. ncbi request reprint The relationship of physical activity and percentage of body fat to the risk of asthma in 8- to 10-year-old children
    Dennis R Ownby
    Department of Pediatrics, Medical College of Georgia, Augusta, Georgia 30912 3790, USA
    J Asthma 44:885-9. 2007
    ..24 (95% CI 1.01-1.52, p = 0.045). Higher levels of physical activity were related to more diagnosed asthma...
  57. ncbi request reprint An outbreak of travel-associated Legionnaires disease and Pontiac fever: the need for enhanced surveillance of travel-associated legionellosis in the United States
    Andrea L Benin
    Epidemic Intelligence Service, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Infect Dis 185:237-43. 2002
    ..001) and IgM seropositivity (P=.007). New laboratory techniques facilitate outbreak investigation; to expedite outbreak interruption and measure the impact of travel-associated legionellosis, surveillance must be improved...

Research Grants13

  1. Mechanism of Endotoxin's Effect On Allergy Risk
    Keoki Williams; Fiscal Year: 2004
    ..It is the hoped that understanding the mechanism of endotoxin's effect will establish new targets for the prevention of allergies. ..
  2. THE CLINICAL EFFECTIVENESS OF PHARMACY ADHERENCE INFORMATION FOR DIABETES CONTROL
    Keoki Williams; Fiscal Year: 2010
    ..Analyses will control for cluster randomization effects. The introduction of sustainable medication adherence monitoring in clinical practice holds great potential to improve health outcomes among patients with diabetes. ..
  3. PHARMACOGENOMICS OF INHALED CORTICOSTEROID RESPONSIVENESS IN PATIENTS WITH ASTHMA
    Keoki Williams; Fiscal Year: 2010
    ..Knowledge gained from this study may help clinicians select asthma treatments most likely to work for their patients, as well as provide insight for future asthma therapeutics. ..
  4. PHARMACOGENOMICS OF INHALED CORTICOSTEROID RESPONSIVENESS IN PATIENTS WITH ASTHMA
    Keoki Williams; Fiscal Year: 2009
    ..Knowledge gained from this study may help clinicians select asthma treatments most likely to work for their patients, as well as provide insight for future asthma therapeutics. ..
  5. USING INFORMATION TECHNOLOGY TO IMPROVE ASTHMA ADHERENCE
    Keoki Williams; Fiscal Year: 2008
    ..abstract_text> ..
  6. Mechanism of Endotoxin's Effect On Allergy Risk
    Keoki Williams; Fiscal Year: 2008
    ..It is the hoped that understanding the mechanism of endotoxin's effect will establish new targets for the prevention of allergies. ..
  7. USING INFORMATION TECHNOLOGY TO IMPROVE ASTHMA ADHERENCE
    Keoki Williams; Fiscal Year: 2007
    ..abstract_text> ..
  8. Mechanism of Endotoxin's Effect On Allergy Risk
    Keoki Williams; Fiscal Year: 2007
    ..It is the hoped that understanding the mechanism of endotoxin's effect will establish new targets for the prevention of allergies. ..
  9. USING INFORMATION TECHNOLOGY TO IMPROVE ASTHMA ADHERENCE
    Keoki Williams; Fiscal Year: 2006
    ..abstract_text> ..
  10. Mechanism of Endotoxin's Effect On Allergy Risk
    Keoki Williams; Fiscal Year: 2006
    ..It is the hoped that understanding the mechanism of endotoxin's effect will establish new targets for the prevention of allergies. ..
  11. USING INFORMATION TECHNOLOGY TO IMPROVE ASTHMA ADHERENCE
    Keoki Williams; Fiscal Year: 2005
    ..abstract_text> ..
  12. Mechanism of Endotoxin's Effect On Allergy Risk
    Keoki Williams; Fiscal Year: 2005
    ..It is the hoped that understanding the mechanism of endotoxin's effect will establish new targets for the prevention of allergies. ..
  13. PHARMACOGENOMICS OF INHALED CORTICOSTEROID RESPONSIVENESS IN PATIENTS WITH ASTHMA
    Keoki Williams; Fiscal Year: 2009
    ..Knowledge gained from this study may help clinicians select asthma treatments most likely to work for their patients, as well as provide insight for future asthma therapeutics. ..