Research Topics
| E RiversSummaryAffiliation: Henry Ford Hospital Country: USA Publications
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Detail Information
Publications
Early and innovative interventions for severe sepsis and septic shock: taking advantage of a window of opportunityEmanuel P Rivers
Department of Emergency Medicine, Henry Ford Hospital, Detroit, Mich, USA
CMAJ 173:1054-65. 2005..This review emphasizes approaches to the early recognition, diagnosis and therapeutic management of sepsis, giving the clinician the most contemporary and practical approaches with which to treat these patients...
Early interventions in severe sepsis and septic shock: a review of the evidence one decade laterE P Rivers
Department of Emergency Medicine and Surgery, Henry Ford Hospital, Wayne State University, Detroit, MI 48202, USA
Minerva Anestesiol 78:712-24. 2012....- Early lactate clearance is associated with biomarkers of inflammation, coagulation, apoptosis, organ dysfunction and mortality in severe sepsis and septic shockH Bryant Nguyen
Department of Emergency Medicine, Loma Linda University, Loma Linda, CA
J Inflamm (Lond) 7:6. 2010..This study examined the association of early lactate clearance with selected inflammatory, coagulation, apoptosis response biomarkers and organ dysfunction scores in severe sepsis and septic shock... - The outcome of patients presenting to the emergency department with severe sepsis or septic shockEmanuel Rivers
Emergency Medicine and Critical Care, Henry Ford Hospital, Detroit, Michigan, USA
Crit Care 10:154. 2006..Current evidence support the endpoints in the EGDT protocol, external validity in regards to outcome benefit and the universal need to improve the quality of care for early sepsis... - The influence of early hemodynamic optimization on biomarker patterns of severe sepsis and septic shockEmanuel P Rivers
Department of Emergency Medicine, Henry Ford Hospital, Wayne State University, Detroit, MI, USA
Crit Care Med 35:2016-24. 2007..Further, the impact of the severity of global tissue hypoxia resulting from resuscitative strategies on these early biomarker patterns remains unknown... - Cocaine use in elder patients presenting to an inner-city emergency departmentEmanuel Rivers
Department of Emergency Medicine and Surgery, Henry Ford Hospital, Detroit, MI 48202, USA
Acad Emerg Med 11:874-7. 2004..To determine the prevalence of cocaine use in a population of elder patients presenting to an inner-city academic emergency department (ED)... - Clinical utility of B-type natriuretic peptide in early severe sepsis and septic shockEmanuel P Rivers
Department of Emergency Medicine, Henry Ford Hospital, Wayne State University, Detroit, Michigan, USA
J Intensive Care Med 22:363-73. 2007..Serial BNP levels may be a useful adjunct in the early detection, stratification, treatment, and prognostication of high-risk patients... 
Early goal-directed therapy in severe sepsis and septic shock: a contemporary review of the literatureEmanuel P Rivers
Department of Emergency Medicine, Henry Ford Health Systems, Detroit, Michigan 48202, USA
Curr Opin Anaesthesiol 21:128-40. 2008..Early goal-directed therapy for severe sepsis and septic shock represents a similar approach. An analysis of the literature assessing external validity and generalizability of this intervention is lacking...- Management of sepsis: early resuscitationEmanuel P Rivers
Department of Emergency Medicine, Henry Ford Health Systems, 270 Clara Ford Pavilion, 2799 West Grand Boulevard, Detroit, MI 48202, USA
Clin Chest Med 29:689-704, ix-x. 2008..Sepsis joins trauma, stroke, and acute myocardial infarction in having "golden hours," representing a critical opportunity early on in the course of disease for actions that offer the most benefit... - Standardized order sets for the treatment of severe sepsis and septic shockEmanuel P Rivers
Henry Ford Hospital, Department of Emergency Medicine, 2799 West Grand Boulevard, 270 Clara Ford Pavillion, Detroit, MI 48202, USA
Expert Rev Anti Infect Ther 7:1075-9. 2009.... - Critical care and emergency medicineEmanuel P Rivers
Department of Emergency Medicine, Henry Ford Hospital, Case Western Reserve University, Detroit, Michigan, USA
Curr Opin Crit Care 8:600-6. 2002.... - Fluid therapy in septic shockEmanuel P Rivers
Department of Emergency Medicine, Henry Ford Hospital, Wayne State University, Detroit, Michigan, USA
Curr Opin Crit Care 16:297-308. 2010..To examine the role of fluid therapy in the pathogenesis of severe sepsis and septic shock. The type, composition, titration, management strategies and complications of fluid administration will be examined in respect to outcomes... - Early goal-directed therapy in the treatment of severe sepsis and septic shockE Rivers
Department of Emergency Medicine, Henry Ford Health Systems, Case Western Reserve University, Detroit, MI 48202, USA
N Engl J Med 345:1368-77. 2001..The purpose of this study was to evaluate the efficacy of early goal-directed therapy before admission to the intensive care unit... - Adrenal insufficiency in high-risk surgical ICU patientsE P Rivers
Department of Surgery, Henry Ford Hospital, Case Western Reserve University, Detroit, MI 48202, USA
Chest 119:889-96. 2001..To examine the incidence and response to treatment of adrenal insufficiency (AI) in high-risk postoperative patients... - Adrenal dysfunction in hemodynamically unstable patients in the emergency departmentE P Rivers
Department of Emergency Medicine, Case Western Reserve University, Henry Ford Hospital, Detroit, MI 48202, USA
Acad Emerg Med 6:626-30. 1999..The authors' objective was to prospectively study adrenal function in a case series of hemodynamically unstable (high-risk) patients from a large, urban ED over a 12-month period... - Health care worker exposure to HIV-1 and HTLV I-II in critically ill, resuscitated emergency department patientsC Lewandowski
Department of Emergency Medicine, Henry Ford Hospital, Detroit, Michigan
Ann Emerg Med 21:1353-9. 1992..The purpose was to determine the seroprevalence of HIV-1 and HTLV I-II in patients undergoing ED resuscitations, the magnitude of health care worker exposure, and risk factors associated with infection... - Emergency department overcrowding in the United States: an emerging threat to patient safety and public healthS Trzeciak
Department of Emergency Medicine, Section of Critical Care Medicine, Robert Wood Johnson Medical School at Camden, University of Medicine and Dentistry of New Jersey, Cooper Health System, Camden, USA
Emerg Med J 20:402-5. 2003..4) Potential solutions for ED overcrowding will require multidisciplinary system-wide support... - Clinical manifestations of disordered microcirculatory perfusion in severe sepsisStephen Trzeciak
Section of Critical Care Medicine and the Department of Emergency Medicine, UMDNJ Robert Wood Johnson Medical School at Camden, Cooper University Hospital, Camden, New Jersey, USA
Crit Care 9:S20-6. 2005..Using new technologies to directly image microcirculatory blood flow will help define the role of microcirculatory dysfunction in oxygen transport and circulatory support in severe sepsis... - The prevalence of latex-specific IgE in patients presenting to an urban emergency departmentMary Grzybowski
Department of Emergency Medicine, School of Medicine, and the Center for Healthcare Effectiveness Research, Wayne State University, Detroit, MI, USA
Ann Emerg Med 40:411-9. 2002..The overall aim of this study was to determine the prevalence of latex IgE seropositivity (L-IgE) in ED patients... - Sepsis: a landscape from the emergency department to the intensive care unitEmanuel P Rivers
Crit Care Med 31:968-9. 2003 - Early goal-directed therapyEmanuel P Rivers
Crit Care Med 32:314-5; author reply 315. 2004 - Early lactate clearance is associated with improved outcome in severe sepsis and septic shockH Bryant Nguyen
Department of Emergency Medicine HBN, Loma Linda University and Medical Center, 11234 Anderson Street, Loma Linda, CA 92354, USA
Crit Care Med 32:1637-42. 2004..We hypothesize that a high lactate clearance in 6 hrs is associated with decreased mortality rate... - Critical care response teams: potential roles for emergency physiciansSuneel Upadhye
Division of Emergency Medicine, McMaster University, Hamilton, Ontario, Canada
CJEM 9:34-7. 2007 - Early goal-directed therapy in severe sepsis and septic shock revisited: concepts, controversies, and contemporary findingsRonny M Otero
Department of Emergency Medicine, Henry Ford Hospital, Detroit, MI 48202, USA
Chest 130:1579-95. 2006..Although EGDT is faced with challenges, a coordinated approach to sepsis management is necessary to duplicate the progress in outcomes seen in patients with conditions such as acute myocardial infarction, stroke, and trauma... - Early goal-directed therapy in severe sepsis and septic shock: converting science to realityEmanuel P Rivers
Chest 129:217-8. 2006 - Targeted resuscitation strategies after injuryRobert N Bilkovski
Department of Emergency Medicine, Henry Ford Hospital, Detroit, Michigan 48202, USA
Curr Opin Crit Care 10:529-38. 2004..The rapid identification and restoration of oxygen debt are central to the resuscitation of the critically ill patient, be it the result of sepsis or trauma... - Emergency medicine and the surviving sepsis campaign: an international approach to managing severe sepsis and septic shockTiffany M Osborn
Ann Emerg Med 46:228-31. 2005 - Severe sepsis and septic shock: review of the literature and emergency department management guidelinesH Bryant Nguyen
Loma Linda University, Loma Linda, CA, USA
Ann Emerg Med 48:28-54. 2006.... - Whole body oxygen consumption and critical oxygen delivery in response to prolonged and severe carbon monoxide poisoningHoward A Smithline
Baystate Medical Center, Department of Emergency Medicine, Baystate, MA, USA
Resuscitation 56:97-104. 2003..In addition, CO exposure does not appear to change the DO(2)crit. The combination of these findings does not support the theory that CO produces a whole body intracellular defect in oxygen utilization... - Critical care medicine training and certification for emergency physiciansDavid T Huang
Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA
Ann Emerg Med 46:217-23. 2005..We therefore propose that all accreditation bodies work cooperatively to create a route to critical care medicine certification for emergency physicians who complete a critical care fellowship... - Clarification of cyanide's effect on oxygen transport characteristics in a canine modelJulius Cuong Pham
Department of Anesthesia and Critical Care, Johns Hopkins University School of Medicine, Johns Hopkins Hospital, Meyer 297, 600 N Wolfe Street, Baltimore, MD 21287, USA
Emerg Med J 24:152-6. 2007..To clarify the cardiovascular mechanisms of cyanide poisoning by evaluating oxygen transport characteristics using a canine model... - Fluid-management strategies in acute lung injury--liberal, conservative, or both?Emanuel P Rivers
N Engl J Med 354:2598-600. 2006 - Prevalence of elevated troponin I in end-stage renal disease patients receiving hemodialysisMichael W Donnino
Department of Emergency Medicine, Henry Ford Hospital, Detroit, MI, USA
Acad Emerg Med 11:979-81. 2004..The objective of this study was to examine the prevalence of elevated cTnI levels in asymptomatic patients with ESRD on hemodialysis... - Critical care medicine training and certification for emergency physiciansDavid T Huang
The CRISMA Laboratory (Clinical Research, Investigation, and Systems Modeling of Acute Illness, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA
Crit Care Med 33:2104-9. 2005..We therefore propose that all accreditation bodies work cooperatively to create a route to CCM certification for emergency physicians who complete a critical care fellowship...