Benjamin Movsas

Summary

Affiliation: Henry Ford Hospital
Country: USA

Publications

  1. pmc Can electronic web-based technology improve quality of life data collection? Analysis of Radiation Therapy Oncology Group 0828
    Benjamin Movsas
    Henry Ford Health System, Detroit, Michigan Electronic address
    Pract Radiat Oncol 4:187-91. 2014
  2. ncbi request reprint Randomized trial of amifostine in locally advanced non-small-cell lung cancer patients receiving chemotherapy and hyperfractionated radiation: radiation therapy oncology group trial 98-01
    Benjamin Movsas
    Department of Radiation Oncology, Henry Ford Health System, 2799 W Grand Blvd, Detroit, MI 48202, USA
    J Clin Oncol 23:2145-54. 2005
  3. doi request reprint Decreasing the adverse effects of cancer therapy: National Cancer Institute guidance for the clinical development of radiation injury mitigators
    Benjamin Movsas
    Department of Radiation Oncology, Henry Ford Hospital, Detroit, Michigan 48202, USA
    Clin Cancer Res 17:222-8. 2011
  4. ncbi request reprint Phase II trial of preoperative chemoradiation with a hyperfractionated radiation boost in locally advanced rectal cancer
    Benjamin Movsas
    Henry Ford Health System, Radiation Oncology, Detroit, MI 48202, USA
    Am J Clin Oncol 29:435-41. 2006
  5. pmc Quality of life supersedes the classic prognosticators for long-term survival in locally advanced non-small-cell lung cancer: an analysis of RTOG 9801
    Benjamin Movsas
    Department of Radiation Oncology, Henry Ford Hospital, Detroit, MI 48202, USA
    J Clin Oncol 27:5816-22. 2009
  6. doi request reprint Randomized phase II trial of cisplatin, etoposide, and radiation followed by gemcitabine alone or by combined gemcitabine and docetaxel in stage III A/B unresectable non-small cell lung cancer
    Benjamin Movsas
    Department of Radiation Oncology, Henry Ford Health Systems, 2799 W Grand Blvd, Detroit, MI 48202, USA
    J Thorac Oncol 5:673-9. 2010
  7. ncbi request reprint A phase II study of concurrent carboplatin and paclitaxel and thoracic radiotherapy for completely resected stage II and IIIA non-small cell lung cancer
    Steven J Feigenberg
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
    J Thorac Oncol 2:287-92. 2007
  8. pmc Prospective randomized phase 2 trial of intensity modulated radiation therapy with or without oncolytic adenovirus-mediated cytotoxic gene therapy in intermediate-risk prostate cancer
    Svend O Freytag
    Department of Radiation Oncology, Henry Ford Health System, Detroit, Michigan Electronic address
    Int J Radiat Oncol Biol Phys 89:268-76. 2014
  9. ncbi request reprint Surgical patterns of care in operable lung carcinoma treated with radiation
    Joe Y Chang
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Thorac Oncol 1:526-31. 2006
  10. doi request reprint Dosimetric verification and clinical evaluation of a new commercially available Monte Carlo-based dose algorithm for application in stereotactic body radiation therapy (SBRT) treatment planning
    Margarida Fragoso
    Henry Ford Health System, Detroit, MI, USA
    Phys Med Biol 55:4445-64. 2010

Collaborators

Detail Information

Publications105 found, 100 shown here

  1. pmc Can electronic web-based technology improve quality of life data collection? Analysis of Radiation Therapy Oncology Group 0828
    Benjamin Movsas
    Henry Ford Health System, Detroit, Michigan Electronic address
    Pract Radiat Oncol 4:187-91. 2014
    ..The purpose of this study was to evaluate the feasibility of an electronic web-based strategy for QOL data collection in a cooperative group radiation oncology trial setting...
  2. ncbi request reprint Randomized trial of amifostine in locally advanced non-small-cell lung cancer patients receiving chemotherapy and hyperfractionated radiation: radiation therapy oncology group trial 98-01
    Benjamin Movsas
    Department of Radiation Oncology, Henry Ford Health System, 2799 W Grand Blvd, Detroit, MI 48202, USA
    J Clin Oncol 23:2145-54. 2005
    ..To test the ability of the cytoprotectant, amifostine, to reduce chemoradiotherapy-induced esophagitis and evaluate its influence on quality of life (QOL) and swallowing symptoms...
  3. doi request reprint Decreasing the adverse effects of cancer therapy: National Cancer Institute guidance for the clinical development of radiation injury mitigators
    Benjamin Movsas
    Department of Radiation Oncology, Henry Ford Hospital, Detroit, Michigan 48202, USA
    Clin Cancer Res 17:222-8. 2011
    ..Ultimately, the goal is to be able to apply such promising agents to improve the quality of life for patients receiving radiotherapy or chemoradiotherapy for cancer...
  4. ncbi request reprint Phase II trial of preoperative chemoradiation with a hyperfractionated radiation boost in locally advanced rectal cancer
    Benjamin Movsas
    Henry Ford Health System, Radiation Oncology, Detroit, MI 48202, USA
    Am J Clin Oncol 29:435-41. 2006
    ..The purpose of this phase II study was to prospectively determine the efficacy of preoperative chemoradiation with a hyperfractionated (Hfx) RT boost to 61.8 Gy in locally advanced rectal cancer...
  5. pmc Quality of life supersedes the classic prognosticators for long-term survival in locally advanced non-small-cell lung cancer: an analysis of RTOG 9801
    Benjamin Movsas
    Department of Radiation Oncology, Henry Ford Hospital, Detroit, MI 48202, USA
    J Clin Oncol 27:5816-22. 2009
    ..To determine the added value of quality of life (QOL) as a prognostic factor for overall survival (OS) in patients with locally advanced non-small-cell lung cancer (NSCLC) treated on Radiation Therapy Oncology Group RTOG-9801...
  6. doi request reprint Randomized phase II trial of cisplatin, etoposide, and radiation followed by gemcitabine alone or by combined gemcitabine and docetaxel in stage III A/B unresectable non-small cell lung cancer
    Benjamin Movsas
    Department of Radiation Oncology, Henry Ford Health Systems, 2799 W Grand Blvd, Detroit, MI 48202, USA
    J Thorac Oncol 5:673-9. 2010
    ..Our study assessed consolidation with either gemcitabine alone or with docetaxel after identical chemoradiation as used in Southwest Oncology Group 9504...
  7. ncbi request reprint A phase II study of concurrent carboplatin and paclitaxel and thoracic radiotherapy for completely resected stage II and IIIA non-small cell lung cancer
    Steven J Feigenberg
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
    J Thorac Oncol 2:287-92. 2007
    ..To determine the feasibility of combining concurrent carboplatin/paclitaxel and thoracic radiotherapy (TRT) for completely resected stage II and IIIA non-small cell lung cancer...
  8. pmc Prospective randomized phase 2 trial of intensity modulated radiation therapy with or without oncolytic adenovirus-mediated cytotoxic gene therapy in intermediate-risk prostate cancer
    Svend O Freytag
    Department of Radiation Oncology, Henry Ford Health System, Detroit, Michigan Electronic address
    Int J Radiat Oncol Biol Phys 89:268-76. 2014
    ..To assess the safety and efficacy of combining oncolytic adenovirus-mediated cytotoxic gene therapy (OAMCGT) with intensity modulated radiation therapy (IMRT) in intermediate-risk prostate cancer...
  9. ncbi request reprint Surgical patterns of care in operable lung carcinoma treated with radiation
    Joe Y Chang
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Thorac Oncol 1:526-31. 2006
    ..To determine the national surgical practice patterns of care for operable lung cancer patients treated with radiation...
  10. doi request reprint Dosimetric verification and clinical evaluation of a new commercially available Monte Carlo-based dose algorithm for application in stereotactic body radiation therapy (SBRT) treatment planning
    Margarida Fragoso
    Henry Ford Health System, Detroit, MI, USA
    Phys Med Biol 55:4445-64. 2010
    ..66 GHz). Overall, the iPlan MC algorithm is demonstrated to be an accurate and efficient dose algorithm, incorporating robust tools for MC-based SBRT treatment planning in the routine clinical setting...
  11. pmc An assessment of PTV margin based on actual accumulated dose for prostate cancer radiotherapy
    Ning Wen
    Department of Radiation Oncology, Henry Ford Health System, Detroit, MI 48202, USA
    Phys Med Biol 58:7733-44. 2013
    ....
  12. doi request reprint Development and clinical evaluation of a three-dimensional cone-beam computed tomography estimation method using a deformation field map
    Lei Ren
    Department of Radiation Oncology, Henry Ford Health System, Detroit, MI, USA
    Int J Radiat Oncol Biol Phys 82:1584-93. 2012
    ..To develop a three-dimensional (3D) cone-beam computed tomography (CBCT) estimation method using a deformation field map, and to evaluate and optimize the efficiency and accuracy of the method for use in the clinical setting...
  13. ncbi request reprint Hypoxic prostate/muscle PO2 ratio predicts for outcome in patients with localized prostate cancer: long-term results
    Aruna Turaka
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Int J Radiat Oncol Biol Phys 82:e433-9. 2012
    ..To correlate tumor oxygenation status with long-term biochemical outcome after prostate brachytherapy...
  14. ncbi request reprint A model for optimizing adenoviral delivery in human cancer gene therapy trials
    Kenneth N Barton
    Department of Radiation Oncology, Henry Ford Health System, Detroit, MI 48202, USA
    Hum Gene Ther 18:562-72. 2007
    ....
  15. ncbi request reprint Phase I trial of replication-competent adenovirus-mediated suicide gene therapy combined with IMRT for prostate cancer
    Svend O Freytag
    Department of Radiation Oncology, Henry Ford Health System, Detroit, Michigan 48202, USA
    Mol Ther 15:1016-23. 2007
    ..01). These results further demonstrate the safety of this investigational approach and raise the possibility that it may have the potential to improve the outcome of conformal radiotherapy in select patient groups...
  16. ncbi request reprint The relationship of increasing radiotherapy dose to reduced distant metastases and mortality in men with prostate cancer
    Rojymon Jacob
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111 2497, USA
    Cancer 100:538-43. 2004
    ..However, there is little direct evidence that dose escalation has an impact on distant metastasis (DM) or overall mortality (OM). These associations were examined in the current study...
  17. ncbi request reprint The influence of gender, race, and marital status on survival in lung cancer patients: analysis of Radiation Therapy Oncology Group trials
    Farzan Siddiqui
    Department of Radiation Oncology, Henry Ford Health System, 2799 West Grand Boulevard, Detroit, MI 48202, USA
    J Thorac Oncol 5:631-9. 2010
    ..A meta-analysis was conducted to determine the influence of gender, race, and marital status on overall survival (OS) in Radiation Therapy Oncology Group nonoperative non-small cell lung cancer trials...
  18. pmc Adaptive seamless design for an efficacy trial of replication-competent adenovirus-mediated suicide gene therapy and radiation in newly-diagnosed prostate cancer (ReCAP Trial)
    Mei Lu
    Department of Public Health Sciences, Henry Ford Health System, Detroit, MI 48202, USA
    Contemp Clin Trials 32:453-60. 2011
    ..There is a challenge in designing an efficacy trial for newly-diagnosed prostate cancer given its long natural history. The regulatory agency recommended a Phase II trial for safety before conducting the efficacy trial...
  19. ncbi request reprint Pretreatment factors significantly influence quality of life in cancer patients: a Radiation Therapy Oncology Group (RTOG) analysis
    Benjamin Movsas
    Radiation Oncology, Henry Ford Health System, Detroit, MI, USA
    Int J Radiat Oncol Biol Phys 65:830-5. 2006
    ..The purpose of this analysis was to assess the impact of pretreatment factors on quality of life (QOL) in cancer patients...
  20. doi request reprint Practical methods for improving dose distributions in Monte Carlo-based IMRT planning of lung wall-seated tumors treated with SBRT
    Michael B Altman
    Department of Radiation Oncology, Henry Ford Health System, Detroit, MI, USA
    J Appl Clin Med Phys 13:4007. 2012
    ....
  21. doi request reprint Image-guided localization accuracy of stereoscopic planar and volumetric imaging methods for stereotactic radiation surgery and stereotactic body radiation therapy: a phantom study
    Jinkoo Kim
    Department of Radiation Oncology, Henry Ford Health System, Detroit, MI, USA
    Int J Radiat Oncol Biol Phys 79:1588-96. 2011
    ..To evaluate the positioning accuracies of two image-guided localization systems, ExacTrac and On-Board Imager (OBI), in a stereotactic treatment unit...
  22. pmc Feasibility of adenovirus-mediated hNIS gene transfer and 131I radioiodine therapy as a definitive treatment for localized prostate cancer
    Kenneth N Barton
    Department of Radiation Oncology, Henry Ford Health System, Detroit, Michigan 48202 3450, USA
    Mol Ther 19:1353-9. 2011
    ..We discuss the obstacles that must be overcome before adenovirus-mediated hNIS gene transfer and (131)I radioiodine therapy can be used as a definitive treatment for localized prostate cancer...
  23. ncbi request reprint Role of prostate dose escalation in patients with greater than 15% risk of pelvic lymph node involvement
    Rojymon Jacob
    Department of Radiation Oncology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA
    Int J Radiat Oncol Biol Phys 61:695-701. 2005
    ..To determine whether the radiation dose is a determinant of clinical outcome in patients with a lymph node risk of >15% treated using whole pelvic (WP), partial pelvic (PP), or prostate only (PO) fields...
  24. pmc Phase I study of noninvasive imaging of adenovirus-mediated gene expression in the human prostate
    Kenneth N Barton
    Department of Radiation Oncology, Henry Ford Health System, Detroit, Michigan 48202, USA
    Mol Ther 16:1761-9. 2008
    ..The results demonstrate that noninvasive imaging of adenovirus-mediated gene therapy in humans is feasible and safe...
  25. ncbi request reprint 2D/3D image fusion for accurate target localization and evaluation of a mask based stereotactic system in fractionated stereotactic radiotherapy of cranial lesions
    Jian Yue Jin
    Department of Radiation Oncology, Henry Ford Hospital, 2799 W Grand Boulevard, Detroit, Michigan 48202, USA
    Med Phys 33:4557-66. 2006
    ..The overall uncertainty of the mask system was +/-4 mm, and the reproducibility was +/-2.9 mm in terms of 95% CI. The study demonstrated that the image guidance system provides accurate and precise target positioning...
  26. ncbi request reprint Comparison of similarity measures for rigid-body CT/Dual X-ray image registrations
    Jinkoo Kim
    Department of Radiation Oncology, Henry Ford Health System, Detroit, MI 48202, USA
    Technol Cancer Res Treat 6:337-46. 2007
    ..In the clinical applications, registrations starting with the mutual information followed by the gradient difference may provide the best accuracy and the most robustness...
  27. doi request reprint Clinical commissioning and use of the Novalis Tx linear accelerator for SRS and SBRT
    Jinkoo Kim
    Department of Radiation Oncology, Henry Ford Health System, Detroit, MI, USA
    J Appl Clin Med Phys 13:3729. 2012
    ....
  28. pmc Evaluation of the deformation and corresponding dosimetric implications in prostate cancer treatment
    Ning Wen
    Department of Radiation Oncology, Henry Ford Health System, Detroit, MI 48202, USA
    Phys Med Biol 57:5361-79. 2012
    ....
  29. ncbi request reprint Amifostine in chemoradiation therapy for non-small cell lung cancer: review of experience and design of a phase II trial assessing subcutaneous and intravenous bolus administration
    Maria Werner-Wasik
    Department of Radiation Oncology, Kimmel Cancer Center, Jefferson Medical College, Thomas Jefferson University Hospital, 111 South 11th Street, Bodine Center, Philadelphia, PA 19107, USA
    Semin Oncol 32:S105-8. 2005
    ..These issues are to be addressed in a randomized phase II trial of amifostine given subcutaneously or via intravenous bolus in non-small cell lung cancer patients undergoing chemoradiation treatment...
  30. ncbi request reprint A TCP model incorporating setup uncertainty and tumor cell density variation in microscopic extension to guide treatment planning
    Jian Yue Jin
    Department of Radiation Oncology, Henry Ford Hospital, Detroit, Michigan 48202, USA
    Med Phys 38:439-48. 2011
    ..In this study, the authors propose a TCP model that can account for the effects of setup uncertainties and tumor cell density decay in the ME region...
  31. ncbi request reprint Gender differences in pretreatment quality of life in a prospective lung cancer trial
    Farzan Siddiqui
    Department of Radiation Oncology, Henry Ford Health System, Detroit, Michigan 48202, USA
    J Support Oncol 6:33-9. 2008
    ..Understanding the interaction between gender and performance status could lead to better prognosticators and potentially could tailor interventions for specific groups of patients with lung cancer...
  32. ncbi request reprint Evaluation of residual patient position variation for spinal radiosurgery using the Novalis image guided system
    Jian Yue Jin
    Department of Radiation Oncology, Henry Ford Hospital, Detroit, Michigan 48202, USA
    Med Phys 35:1087-93. 2008
    ..This study evaluates such position uncertainty for spinal radiosurgery patients...
  33. ncbi request reprint Quantification of incidental dose to potential clinical target volume (CTV) under different stereotactic body radiation therapy (SBRT) techniques for non-small cell lung cancer - tumor motion and using internal target volume (ITV) could improve dose distr
    Jian Yue Jin
    Department of Radiation Oncology, Henry Ford Hospital, 2799 W Grand Boulevard, Detroit, MI 48202, USA
    Radiother Oncol 85:267-76. 2007
    ..This study aimed to quantify the incidental dose to the potential CTV under different SBRT techniques...
  34. ncbi request reprint Salvage reirradiation for recurrent glioblastoma with radiosurgery: radiographic response and improved survival
    Mehul Patel
    Henry Ford Health System, Detroit, MI, USA
    J Neurooncol 92:185-91. 2009
    ..To determine the radiographic and clinical efficacy of stereotactic single dose radiosurgery (SRS) and fractionated stereotactic radiotherapy (FSRT) as salvage therapy for glioblastoma (GBM) at recurrence...
  35. ncbi request reprint Stereotactic body radiation therapy for primary, recurrent, and metastatic tumors in the head-and-neck region
    Farzan Siddiqui
    Department of Radiation Oncology, Henry Ford Health System, Detroit, MI 48202, USA
    Int J Radiat Oncol Biol Phys 74:1047-53. 2009
    ..To determine the feasibility, safety, and efficacy of stereotactic body radiation therapy (SBRT), also known as radiosurgery, in patients with head-and-neck cancers...
  36. ncbi request reprint Phase I study of thoracic radiation dose escalation with concurrent chemotherapy for patients with limited small-cell lung cancer: Report of Radiation Therapy Oncology Group (RTOG) protocol 97-12
    Ritsuko Komaki
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 62:342-50. 2005
    ..The purpose of RTOG 97-12 was to determine the maximum tolerated dose (MTD) of thoracic radiation therapy (RT) with concurrent chemotherapy for patients with limited-stage small-cell lung cancer...
  37. ncbi request reprint Replication-competent adenovirus-mediated suicide gene therapy with radiation in a preclinical model of pancreatic cancer
    Svend O Freytag
    Department of Radiation Oncology, Henry Ford Health System, Detroit, Michigan 48202, USA
    Mol Ther 15:1600-6. 2007
    ..Hence they provide the scientific basis for an ongoing Phase I trial in pancreatic cancer...
  38. ncbi request reprint Who enrolls onto clinical oncology trials? A radiation Patterns Of Care Study analysis
    Benjamin Movsas
    Department of Radiation Oncology, Henry Ford Health System, 2799 West Grand Boulevard, Detroit, MI 48202, USA
    Int J Radiat Oncol Biol Phys 68:1145-50. 2007
    ..To identify factors significantly influencing accrual to clinical protocols by analyzing radiation Patterns of Care Study (PCS) surveys of 3,047 randomly selected radiotherapy (RT) patients...
  39. ncbi request reprint Biochemical failure as a determinant of distant metastasis and death in prostate cancer treated with radiotherapy
    Alan Pollack
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Int J Radiat Oncol Biol Phys 57:19-23. 2003
    ..However, little evidence is available to show that BF is associated with death for patents with prostate cancer treated with radiotherapy. We examined the relationship between BF and death from prostate cancer...
  40. doi request reprint Impact of fraction size on lung radiation toxicity: hypofractionation may be beneficial in dose escalation of radiotherapy for lung cancers
    Jin Yue Jin
    Department of Radiation Oncology, Henry Ford Hospital, Detroit, MI 48202, USA
    Int J Radiat Oncol Biol Phys 76:782-8. 2010
    ..To assess how fraction size impacts lung radiation toxicity and therapeutic ratio in treatment of lung cancers...
  41. pmc Dosimetry and preliminary acute toxicity in the first 100 men treated for prostate cancer on a randomized hypofractionation dose escalation trial
    Alan Pollack
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Int J Radiat Oncol Biol Phys 64:518-26. 2006
    ..The dosimetry and acute toxicity are described in the first 100 men enrolled in a randomized trial...
  42. doi request reprint Examining margin reduction and its impact on dose distribution for prostate cancer patients undergoing daily cone-beam computed tomography
    Rabih Hammoud
    Josephine Ford Downriver Center for Oncology, Henry Ford Health System, Brownstown, MI, USA
    Int J Radiat Oncol Biol Phys 71:265-73. 2008
    ..To examine the dosimetric impact of margin reduction and quantify residual error after three-dimensional (3D) image registration using daily cone-beam computed tomography (CBCT) for prostate cancer patients...
  43. ncbi request reprint Technical and clinical experience with spine radiosurgery: a new technology for management of localized spine metastases
    Jian Yue Jin
    Department of Radiation Oncology, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, MI 48202, USA
    Technol Cancer Res Treat 6:127-33. 2007
    ..Patients tolerated the treatment well without major acute toxicities. Image guided spinal radiosurgery can be successfully applied to treat patients with focal spine metastases...
  44. ncbi request reprint Mindless or mindful? Radiation oncologists' perspectives on the evolution of prostate cancer treatment
    Alan Pollack
    Department of Radiation Oncology, Fox Chase Cancer Center, 7701 Burholme Avenue, Philadelphia, PA 19111, USA
    Urol Clin North Am 30:337-49, x. 2003
    ..In summary, advances in radiation oncology have led to significant gains in prostate cancer control. Clinical prognostic factor-based patient selection is central to the optimization of outcome...
  45. ncbi request reprint A prospective phase II study of induction carboplatin and vinorelbine followed by concomitant topotecan and accelerated radiotherapy (ART) in locally advanced non-small cell lung cancer (NSCLC)
    Samir H Patel
    Department of Radiation Oncology, Henry Ford Hospital, Detroit, Michigan 48202, USA
    J Thorac Oncol 2:831-7. 2007
    ..We investigated the toxicity, response rate, and overall survival (OS) with induction carboplatin and vinorelbine followed by concomitant topotecan and ART in patients with locally advanced/unresectable NSCLC...
  46. ncbi request reprint Pretreatment quality of life predicts for locoregional control in head and neck cancer patients: a radiation therapy oncology group analysis
    Farzan Siddiqui
    Department of Radiation Oncology, Henry Ford Health System, Detroit, MI 48202, USA
    Int J Radiat Oncol Biol Phys 70:353-60. 2008
    ....
  47. doi request reprint Radiation pulmonary toxicity: from mechanisms to management
    Paul R Graves
    Department of Radiation Oncology, Virginia Commonwealth University, Richmond, VA, USA
    Semin Radiat Oncol 20:201-7. 2010
    ....
  48. ncbi request reprint Utilize target motion to cover clinical target volume (ctv)--a novel and practical treatment planning approach to manage respiratory motion
    Jian Yue Jin
    Department of Radiation Oncology, Henry Ford Hospital, Detroit, MI 48202, USA
    Radiother Oncol 89:292-303. 2008
    ..To use probability density function (PDF) to model motion effects and incorporate this information into treatment planning for lung cancers...
  49. pmc A novel method of boron delivery using sodium iodide symporter for boron neutron capture therapy
    Sanath Kumar
    Department of Radiation Oncology, Henry Ford Health System, Detroit, MI, USA
    J Radiat Res 51:621-6. 2010
    ..We conclude that adenovirus expressing NIS has the potential to be used as a novel boron delivery agent and should be explored for future clinical applications...
  50. ncbi request reprint Incorporating clinical measurements of hypoxia into tumor local control modeling of prostate cancer: implications for the alpha/beta ratio
    Alan E Nahum
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Int J Radiat Oncol Biol Phys 57:391-401. 2003
    ....
  51. doi request reprint Radiosurgical decompression of metastatic epidural compression
    Samuel Ryu
    Department of Radiation Oncology, Henry Ford Hospital, Detroit, Michigan 48202, USA
    Cancer 116:2250-7. 2010
    ..Therefore, a clinical trial was performed to quantitatively determine the degree of epidural decompression by radiosurgery of metastatic epidural compression...
  52. pmc Randomized trial of hypofractionated external-beam radiotherapy for prostate cancer
    Alan Pollack
    Alan Pollack, Gail Walker, and Radka Stoyanova, University of Miami Miller School of Medicine, Miami, FL Eric M Horwitz, Robert Price, Richard E Greenberg, Robert G Uzzo, Charlie Ma, and Mark K Buyyounouski, Fox Chase Cancer Center, Philadelphia, PA Steven Feigenberg, University of Maryland, Baltimore, MD Andre A Konski, Wayne State University Medical Center and Benjamin Movsas, Henry Ford Hospital, Detroit, MI
    J Clin Oncol 31:3860-8. 2013
    ..To determine if escalated radiation dose using hypofractionation significantly reduces biochemical and/or clinical disease failure (BCDF) in men treated primarily for prostate cancer...
  53. ncbi request reprint Pain control by image-guided radiosurgery for solitary spinal metastasis
    Samuel Ryu
    Department of Radiation Oncology, Henry Ford Hospital, Detroit, MI 48202, USA
    J Pain Symptom Manage 35:292-8. 2008
    ..This experience demonstrates that spinal radiosurgery can achieve rapid and durable pain relief. Single-dose radiosurgery has a potential to be a viable treatment option for single spinal metastasis...
  54. doi request reprint Radiosurgery to the surgical cavity as adjuvant therapy for resected brain metastasis
    Jared R Robbins
    Department of Radiation Oncology, Henry Ford Hospital, Detroit, Michigan 48202, USA
    Neurosurgery 71:937-43. 2012
    ..The standard treatment of resected brain metastasis is whole-brain radiotherapy (WBRT). To avoid the potential toxicity of WBRT and to improve local control, we have used radiosurgery alone to the surgical cavity...
  55. ncbi request reprint Clinical use of dual image-guided localization system for spine radiosurgery
    Ning Wen
    Department of Radiation Oncology, Henry Ford Health System, 2799 W Grand Blvd, Detroit, MI 48202, USA
    Technol Cancer Res Treat 11:123-31. 2012
    ..The discrepancies between the isocenter between the ExacTrac and CBCT in four dimensions (three translations and one rotation) were recorded and statistically analyzed using two-tailed t-test...
  56. pmc A finite element method to correct deformable image registration errors in low-contrast regions
    Hualiang Zhong
    Department of Radiation Oncology, Henry Ford Health System, Detroit, MI, USA
    Phys Med Biol 57:3499-515. 2012
    ..6 GHz computer. This study has demonstrated that the FEM can be integrated with intensity-based image registration algorithms to improve their registration accuracy, especially in low-contrast regions...
  57. ncbi request reprint Exploring the role of the radioprotector amifostine in locally advanced non-small cell lung cancer: Radiation Therapy Oncology Group trial 98-01
    Benjamin Movsas
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Semin Radiat Oncol 12:40-5. 2002
    ....
  58. doi request reprint ACR appropriateness criteria on nonsurgical treatment for non-small-cell lung cancer: poor performance status or palliative intent
    Kenneth E Rosenzweig
    Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York 10065 6007, USA
    J Am Coll Radiol 6:85-95. 2009
    ..Biologic therapies such as erlotinib and bevacizumab have been incorporated into every phase of chemotherapy with good results...
  59. pmc Analysis of outcomes in radiation oncology: an integrated computational platform
    Dezhi Liu
    Department of Radiation Oncology, Henry Ford Health System, 2799 West Grand Boulevard, Detroit, Michigan 48202, USA
    Med Phys 36:1680-9. 2009
    ..In addition the database is web-based and accessible by multiple users, facilitating its convenient application and use...
  60. ncbi request reprint Stereotactic IMRT for prostate cancer: setup accuracy of a new stereotactic body localization system
    Lu Wang
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
    J Appl Clin Med Phys 5:18-28. 2004
    ..A rigid frame system serves as a reliable alignment reference in terms of repositioning patients into the planning position, while skin-based reference showed larger deviations in repositioning patients...
  61. ncbi request reprint Measurement of intrafractional prostate motion using magnetic resonance imaging
    Dennis Mah
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA
    Int J Radiat Oncol Biol Phys 54:568-75. 2002
    ..To quantify the three-dimensional intrafractional prostate motion over typical treatment time intervals with cine-magnetic resonance imaging (cine MRI) studies...
  62. ncbi request reprint Clinical, dosimetric, and radiographic correlation of radiation injury involving the brainstem and the medial temporal lobes following stereotactic radiotherapy for neoplasms of central skull base
    Stefano Schipani
    Department of Radiation Oncology, Henry Ford Health System, 2799 West Grand Blvd, Detroit, MI, 48202, USA
    J Neurooncol 98:177-84. 2010
    ..Brainstem lesions occurred earlier than temporal lobe RI. The majority of the RI lesions, not mixed with the tumor in this study, showed radiographic and clinical improvement with steroid and symptomatic treatments...
  63. pmc Primary analysis of a phase II randomized trial Radiation Therapy Oncology Group (RTOG) 0212: impact of different total doses and schedules of prophylactic cranial irradiation on chronic neurotoxicity and quality of life for patients with limited-disease
    Aaron H Wolfson
    Department of Radiation Oncology, University of Miami Miller School of Medicine, Miami, FL 33136, USA
    Int J Radiat Oncol Biol Phys 81:77-84. 2011
    ....
  64. ncbi request reprint Combining scatter reduction and correction to improve image quality in cone-beam computed tomography (CBCT)
    Jian Yue Jin
    Department of Radiation Oncology, Henry Ford Hospital, Detroit, Michigan 48202, USA
    Med Phys 37:5634-44. 2010
    ..This study aims to evaluate the feasibility of the proposed approach...
  65. pmc Impact of gender, partner status, and race on locoregional failure and overall survival in head and neck cancer patients in three radiation therapy oncology group trials
    Thomas J Dilling
    Department of Radiation Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
    Int J Radiat Oncol Biol Phys 81:e101-9. 2011
    ..We investigated the impact of race, in conjunction with gender and partner status, on locoregional control (LRC) and overall survival (OS) in three head and neck trials conducted by the Radiation Therapy Oncology Group (RTOG)...
  66. doi request reprint Prostate localization on daily cone-beam computed tomography images: accuracy assessment of similarity metrics
    Jinkoo Kim
    Department of Radiation Oncology, Henry Ford Health System, Detroit, MI 48202, USA
    Int J Radiat Oncol Biol Phys 77:1257-65. 2010
    ..To evaluate different similarity metrics (SM) using natural calcifications and observation-based measures to determine the most accurate prostate and seminal vesicle localization on daily cone-beam CT (CBCT) images...
  67. ncbi request reprint Disadvantage of men living alone participating in Radiation Therapy Oncology Group head and neck trials
    Andre A Konski
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    J Clin Oncol 24:4177-83. 2006
    ..This study evaluated whether males without partners were disadvantaged for survival in Radiation Therapy Oncology Group (RTOG) head and neck cancer clinical trials...
  68. ncbi request reprint Partial volume tolerance of the spinal cord and complications of single-dose radiosurgery
    Samuel Ryu
    Department of Radiation Oncology, Henry Ford Hospital, Detroit, Michigan 48202, USA
    Cancer 109:628-36. 2007
    ..The tolerance of partial volume of the spinal cord may determine the extent of clinical application. The study analyzed the partial volume tolerance of the human spinal cord to single fraction radiosurgery...
  69. ncbi request reprint A method for increased dose conformity and segment reduction for SMLC delivered IMRT treatment of the prostate
    Robert A Price
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Int J Radiat Oncol Biol Phys 57:843-52. 2003
    ..The focus of this work is to develop a practical planning method that results in increased dose conformity and reduced treatment time for segmental multileaf collimation (sMLC) based intensity-modulated radiation therapy (IMRT) delivery...
  70. ncbi request reprint Prostate cancer gene therapy clinical trials
    Svend O Freytag
    Department of Radiation Oncology, Henry Ford Health System, Detroit, Michigan 48202, USA
    Mol Ther 15:1042-52. 2007
    ..Much work lies ahead. Nevertheless, for the time being, these studies provide hope that gene therapy may someday earn a place in the management of prostate cancer...
  71. ncbi request reprint Single fraction spine radiosurgery for myeloma epidural spinal cord compression
    Ryan Jin
    Department of Radiation Oncology, Henry Ford Hospital, Detroit, MI 48202, USA
    J Exp Ther Oncol 8:35-41. 2009
    ..Single fraction radiosurgery achieved an excellent clinical and radiographic response of myeloma epidural spinal cord compression. Radiosurgery can be a viable treatment option for myeloma epidural compression...
  72. ncbi request reprint How often are previously undetected radiographic abnormalities detected at the time of CT simulation for breast cancer patients?
    Sishir Rao
    Department of Radiation Oncology, Henry Ford Hospital, 2799 W Grand Blvd, Detroit, MI 48202, USA
    Am J Clin Oncol 33:262-4. 2010
    ..The purpose of this analysis was to determine the percentage of cases in which a previously undetected radiographic finding was found on review of CT simulation images by diagnostic radiology...
  73. doi request reprint Can physicians accurately predict survival time in patients with metastatic cancer? Analysis of RTOG 97-14
    William F Hartsell
    Department of Radiation Oncology, Advocate Good Samaritan Cancer Center, Downers Grove, Illinois 60515, USA
    J Palliat Med 11:723-8. 2008
    ..To determine if physician prediction of survival duration (PSD) is accurate for patients with metastatic breast or prostate cancer...
  74. ncbi request reprint A technique of using gated-CT images to determine internal target volume (ITV) for fractionated stereotactic lung radiotherapy
    Jian Yue Jin
    Department of Radiation Oncology, Henry Ford Hospital, Detroit, MI, USA
    Radiother Oncol 78:177-84. 2006
    ..To develop and evaluate a technique and procedure of using gated-CT images in combination with PET image to determine the internal target volume (ITV), which could reduce the planning target volume (PTV) with adequate target coverage...
  75. ncbi request reprint MRI simulation: effect of gradient distortions on three-dimensional prostate cancer plans
    Dennis Mah
    Department of Radiation Oncology, Fox Chase Cancer Center, 7701 Burholme Avenue, Philadelphia, PA 19111, USA
    Int J Radiat Oncol Biol Phys 53:757-65. 2002
    ..To quantify the dosimetric consequences of external patient contour distortions produced on low-field and high-field MRIs for external beam radiation of prostate cancer...
  76. ncbi request reprint Hypoxic prostate/muscle pO2 ratio predicts for biochemical failure in patients with prostate cancer: preliminary findings
    Benjamin Movsas
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
    Urology 60:634-9. 2002
    ..To investigate whether low partial pressure of oxygen (PO2) in prostate cancer (CaP) predicts for biochemical outcome after radiotherapy. We previously reported that hypoxic regions exist in human CaP...
  77. doi request reprint Quality-of-life concerns in lung cancer patients
    Farzan Siddiqui
    Department of Radiation Oncology, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, MI 48202, USA
    Expert Rev Pharmacoecon Outcomes Res 10:667-76. 2010
    ..This article provides an overview of the importance, methodology, analysis and presentation of health-related quality of life in lung cancer trials, and also discusses some of the limitations and challenges of such studies...
  78. ncbi request reprint Effects of prescription depth, cylinder size, treatment length, tip space, and curved end on doses in high-dose-rate vaginal brachytherapy
    Shidong Li
    Department of Radiation Oncology, Henry Ford Health System, Detroit, Michigan 48202, USA
    Int J Radiat Oncol Biol Phys 67:1268-77. 2007
    ..To determine the effects of the prescription depth, cylinder size, treatment length, tip space, and curved end on high-dose-rate vaginal brachytherapy (HDR-VBT) of endometrial cancer...
  79. pmc Measurement of regional compliance using 4DCT images for assessment of radiation treatment
    Hualiang Zhong
    Department of Radiation Oncology, Henrgy Ford Health System, 2799 West Grand Boulevard, Detroit, Michigan 48202, USA
    Med Phys 38:1567-78. 2011
    ..The purpose of this study is to present a 4DCT-based method to measure the regional ventilation capability, namely, regional compliance, for the evaluation of radiation-induced lung damage...
  80. ncbi request reprint Pharmacologic normal tissue protection in clinical radiation oncology: focus on amifostine
    Loren K Mell
    University of California San Diego, Department of Radiation Oncology, La Jolla, California, USA
    Expert Opin Drug Metab Toxicol 4:1341-50. 2008
    ..Amifostine is a cytoprotector that can reduce toxicity and potentially improve the therapeutic ratio of radiotherapy...
  81. ncbi request reprint A technique of quantitatively monitoring both respiratory and nonrespiratory motion in patients using external body markers
    Jian Yue Jin
    Henry Ford Hospital, Detroit, Michigan 48202, USA
    Med Phys 34:2875-81. 2007
    ..This technique can potentially be used to control the nonrespiratory motion during SBRT. However, further validation is required for its clinical use...
  82. ncbi request reprint Dose delivered from Varian's CBCT to patients receiving IMRT for prostate cancer
    Ning Wen
    Henry Ford Health System, Detroit, MI, USA
    Phys Med Biol 52:2267-76. 2007
    ..The surface and in vivo doses were also measured for phantoms at the central-axis setup. The difference was less than approximately 12% to the table-drop setup...
  83. ncbi request reprint Quality-of-life trials in lung cancer: past achievements and future challenges
    Benjamin Movsas
    Department of Radiation Oncology, Fox Chase Cancer Center, 7701 Burholme Avenue, Philadelphia, PA 19111, USA
    Hematol Oncol Clin North Am 18:161-86. 2004
    ..Future studies should focus on incorporating QOL into phase III studies with clear hypotheses that can ultimately lead to clinically meaningful interventions...
  84. ncbi request reprint Imaging response in malignant glioma, RTOG 90-06
    Robert A Lustig
    Hospital of the University of Pennsylvania, Department of Radiation Oncology, Philadelphia, PA 19104, USA
    Am J Clin Oncol 30:32-7. 2007
    ..This study compared patients treated with hyperfractionated radiation and 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) to standard fractionation and BCNU...
  85. ncbi request reprint Role of adjuvant therapy in resected stage II/IIIA non-small-cell lung cancer
    Benjamin Movsas
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
    Oncology (Williston Park) 16:90-5, 100; discussion 100-2, 105-6. 2002
    ..Future strategies include novel chemotherapy, methods to reduce toxicity, the emerging role of neoadjuvant therapy, and the promise of new biologic agents...
  86. ncbi request reprint Five-year follow-up of trial of replication-competent adenovirus-mediated suicide gene therapy for treatment of prostate cancer
    Svend O Freytag
    Department of Radiation Oncology, Henry Ford Health System, Detroit, Michigan, USA
    Mol Ther 15:636-42. 2007
    ..Given the high morbidity associated with AST, we believe this approach could provide an attractive treatment option for selection of patients experiencing PSA relapse following definitive therapy...
  87. ncbi request reprint Radiation esophagitis: Predictive factors and preventive strategies
    Jeffrey Bradley
    Department of Radiation Oncology, Alvin J Siteman Cancer Center, Washington University School of Medicine, St Louis, MO 63110, USA
    Semin Radiat Oncol 14:280-6. 2004
    ..Preventive strategies to minimize this toxicity also are explored. Overall, this article reviews the current understanding of radiation toxicity for the esophagus...
  88. doi request reprint Prospective evaluation of quality of life and neurocognitive effects in patients with multiple brain metastases receiving whole-brain radiotherapy with or without thalidomide on Radiation Therapy Oncology Group (RTOG) trial 0118
    Benjamin W Corn
    Department of Radiation Oncology, Tel Aviv Medical Center, Tel Aviv, Israel
    Int J Radiat Oncol Biol Phys 71:71-8. 2008
    ..This secondary analysis of 156 patients examined neurocognitive and quality of life (QOL) outcomes...
  89. ncbi request reprint Effect of amifostine on response rates in locally advanced non-small-cell lung cancer patients treated on randomized controlled trials: a meta-analysis
    Loren K Mell
    Department of Radiation and Cellular Oncology, University of Chicago, Chicago, IL, USA
    Int J Radiat Oncol Biol Phys 68:111-8. 2007
    ..Studies with sufficient statistical power to address this question are lacking...
  90. ncbi request reprint Comparing cancer patients who enroll in a smoking cessation program at a comprehensive cancer center with those who decline enrollment
    Robert A Schnoll
    Division of Population Science, Fox Chase Cancer Center, 510 Township Line Road, Cheltenham, Pennsylvania 19012, USA
    Head Neck 26:278-86. 2004
    ..We examined reasons patients provide for declining smoking treatment and compared treatment decliners to enrollees...
  91. doi request reprint A phase III study of conventional radiation therapy plus thalidomide versus conventional radiation therapy for multiple brain metastases (RTOG 0118)
    Jonathan P S Knisely
    Department of Therapeutic Radiology, Yale University School of Medicine and Yale Cancer Center, New Haven, CT 06520 8040, USA
    Int J Radiat Oncol Biol Phys 71:79-86. 2008
    ..To compare whole-brain radiation therapy (WBRT) with WBRT combined with thalidomide for patients with brain metastases not amenable to resection or radiosurgery...
  92. ncbi request reprint Patterns of care survey (PCS) in lung cancer: how well does current U.S. practice with chemotherapy in the non-metastatic setting follow the literature?
    Corey J Langer
    Fox Chase Cancer Center, 333 Cotman AVE, Philadelphia, PA 19111, USA
    Lung Cancer 48:93-102. 2005
    ..ASCO 2000;19:484a; Furuse. JCO 1999;17:2692-9; Zatloukal. ASCO 2002;A-1159]. Data are less secure regarding the role of chemotherapy in stage I and II NSCLC...
  93. ncbi request reprint A phase III comparison of radiation therapy with or without recombinant beta-interferon for poor-risk patients with locally advanced non-small-cell lung cancer (RTOG 93-04)
    Jeffrey D Bradley
    Radiation Oncology Center, Washington University Medical Center, St Louis, MO 63110, USA
    Int J Radiat Oncol Biol Phys 52:1173-9. 2002
    ..Based on these data, the Radiation Therapy Oncology Group (RTOG) initiated a Phase III trial to test the efficacy of beta-interferon in poor-risk patients with Stages IIIA and IIIB non-small-cell lung carcinoma...
  94. ncbi request reprint Emotional well-being does not predict survival in head and neck cancer patients: a Radiation Therapy Oncology Group study
    James C Coyne
    Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Cancer 110:2568-75. 2007
    ..The objective of the current study was to examine whether emotional well-being predicted survival in a large sample of patients with head and neck cancer who were participating in multicenter clinical trials...
  95. ncbi request reprint Recent advances and dilemmas in the radiotherapeutic management of locally advanced non-small cell lung cancer
    Benjamin Movsas
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA
    Methods Mol Med 75:489-505. 2003
  96. ncbi request reprint Treatment of stage II non-small cell lung cancer
    Walter J Scott
    Department of Surgical Oncology, Section of Thoracic Surgical Oncology, Fox Chase Cancer Center, 7701 Burholme Avenue, Philadelphia, PA 19111, USA
    Chest 123:188S-201S. 2003
    ..Superior sulcus tumors are discussed elsewhere in these guidelines...
  97. ncbi request reprint Randomized trial of short- versus long-course radiotherapy for palliation of painful bone metastases
    William F Hartsell
    Advocate Good Samaritan Hospital, Downers Grove, IL, USA
    J Natl Cancer Inst 97:798-804. 2005
    ..We investigated whether 8 Gy delivered in a single treatment fraction provides pain and narcotic relief that is equivalent to that of the standard treatment course of 30 Gy delivered in 10 treatment fractions over 2 weeks...
  98. ncbi request reprint Imaging to optimally stage lung cancer: conventional modalities and PET/CT
    Mylene T Truong
    Department of Diagnostic Radiology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Am Coll Radiol 1:957-64. 2004
    ..This article reviews current recommendations regarding the staging of patients with NSCLC and addresses the role of PET/CT...
  99. ncbi request reprint Phase I study of radical thoracic radiation, weekly irinotecan, and cisplatin in locally advanced non-small cell lung carcinoma
    Corey J Langer
    Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    J Thorac Oncol 2:203-9. 2007
    ..6 months in advanced NSCLC (Jagasia et al.; Clinical Cancer Research 7: 68, 2001). A weekly schedule for each agent (versus less frequent doses) limits toxicity and increases the opportunity for radiosensitization...
  100. ncbi request reprint Androgen suppression adjuvant to definitive radiotherapy in prostate carcinoma--long-term results of phase III RTOG 85-31
    Miljenko V Pilepich
    University of California, Los Angeles, School of Medicine, Los Angeles, CA, USA
    Int J Radiat Oncol Biol Phys 61:1285-90. 2005
    ..Radiation Therapy Oncology Group protocol 85-31 was designed to evaluate the effectiveness of adjuvant androgen suppression, using goserelin, in unfavorable prognosis carcinoma of the prostate treated with definitive radiotherapy (RT)...
  101. ncbi request reprint Quality of life in oncology trials: a clinical guide
    Benjamin Movsas
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Semin Radiat Oncol 13:235-47. 2003
    ..The future challenge will be to translate QOL results into clinically meaningful interventions...