Mariela Mendez

Summary

Affiliation: Henry Ford Hospital
Country: USA

Publications

  1. doi request reprint Renin release: role of SNAREs
    Mariela Mendez
    Hypertension and Vascular Research Division, Department of Internal Medicine, Henry Ford Hospital, Detroit, Michigan
    Am J Physiol Regul Integr Comp Physiol 307:R484-6. 2014
  2. pmc Role of the SNARE protein SNAP23 on cAMP-stimulated renin release in mouse juxtaglomerular cells
    Mariela Mendez
    E and R 7069, 2799 W Grand Blvd, Detroit, MI 48202
    Am J Physiol Renal Physiol 304:F498-504. 2013
  3. pmc Vesicle-associated membrane protein-2 (VAMP2) mediates cAMP-stimulated renin release in mouse juxtaglomerular cells
    Mariela Mendez
    Hypertension and Vascular Research Division, Department of Internal Medicine, Henry Ford Hospital, Detroit, Michigan 48202, USA
    J Biol Chem 286:28608-18. 2011
  4. pmc Juxtaglomerular cell CaSR stimulation decreases renin release via activation of the PLC/IP(3) pathway and the ryanodine receptor
    M Cecilia Ortiz-Capisano
    Hypertension and Vascular Research Division, Department of Internal Medicine, Henry Ford Hospital, Detroit, MI 48202, USA
    Am J Physiol Renal Physiol 304:F248-56. 2013

Collaborators

  • M Cecilia Ortiz-Capisano
  • William H Beierwaltes
  • Mahendranath Reddy
  • Jeffrey L Garvin

Detail Information

Publications4

  1. doi request reprint Renin release: role of SNAREs
    Mariela Mendez
    Hypertension and Vascular Research Division, Department of Internal Medicine, Henry Ford Hospital, Detroit, Michigan
    Am J Physiol Regul Integr Comp Physiol 307:R484-6. 2014
    ..This minireview focuses on the current knowledge of the proteins that facilitate renin-granule exocytosis. We discuss the identity of potential candidates that mediate the signaling and final steps of exocytosis of the renin granule. ..
  2. pmc Role of the SNARE protein SNAP23 on cAMP-stimulated renin release in mouse juxtaglomerular cells
    Mariela Mendez
    E and R 7069, 2799 W Grand Blvd, Detroit, MI 48202
    Am J Physiol Renal Physiol 304:F498-504. 2013
    ..We concluded that the SNARE protein SNAP23 mediates cAMP-stimulated renin release. These data show that renin release is a SNARE-dependent process...
  3. pmc Vesicle-associated membrane protein-2 (VAMP2) mediates cAMP-stimulated renin release in mouse juxtaglomerular cells
    Mariela Mendez
    Hypertension and Vascular Research Division, Department of Internal Medicine, Henry Ford Hospital, Detroit, Michigan 48202, USA
    J Biol Chem 286:28608-18. 2011
    ..We conclude that VAMP2 and VAMP3 are expressed in JG cells, but only VAMP2 is targeted to renin-containing granules and mediates the stimulatory effect of cAMP on renin exocytosis...
  4. pmc Juxtaglomerular cell CaSR stimulation decreases renin release via activation of the PLC/IP(3) pathway and the ryanodine receptor
    M Cecilia Ortiz-Capisano
    Hypertension and Vascular Research Division, Department of Internal Medicine, Henry Ford Hospital, Detroit, MI 48202, USA
    Am J Physiol Renal Physiol 304:F248-56. 2013
    ..001). We conclude stimulating JG cell CaSR activates G(q), initiating the PLC/IP(3) pathway, activating RyR, increasing intracellular calcium, and resulting in calcium-mediated renin inhibition...