- Role of the SNARE protein SNAP23 on cAMP-stimulated renin release in mouse juxtaglomerular cellsMariela Mendez
E and R 7069, 2799 W Grand Blvd, Detroit, MI 48202
Am J Physiol Renal Physiol 304:F498-504. 2013..We concluded that the SNARE protein SNAP23 mediates cAMP-stimulated renin release. These data show that renin release is a SNARE-dependent process...
- Vesicle-associated membrane protein-2 (VAMP2) mediates cAMP-stimulated renin release in mouse juxtaglomerular cellsMariela Mendez
Hypertension and Vascular Research Division, Department of Internal Medicine, Henry Ford Hospital, Detroit, Michigan 48202, USA
J Biol Chem 286:28608-18. 2011..We conclude that VAMP2 and VAMP3 are expressed in JG cells, but only VAMP2 is targeted to renin-containing granules and mediates the stimulatory effect of cAMP on renin exocytosis...
- Juxtaglomerular cell CaSR stimulation decreases renin release via activation of the PLC/IP(3) pathway and the ryanodine receptorM Cecilia Ortiz-Capisano
Hypertension and Vascular Research Division, Department of Internal Medicine, Henry Ford Hospital, Detroit, MI 48202, USA
Am J Physiol Renal Physiol 304:F248-56. 2013..001). We conclude stimulating JG cell CaSR activates G(q), initiating the PLC/IP(3) pathway, activating RyR, increasing intracellular calcium, and resulting in calcium-mediated renin inhibition...