Steven N Kalkanis

Summary

Affiliation: Henry Ford Hospital
Country: USA

Publications

  1. pmc The role of surgical resection in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline
    Steven N Kalkanis
    Department of Neurosurgery, Henry Ford Health System, 2799 West Grand Blvd, K 11, Detroit, MI 48202, USA
    J Neurooncol 96:33-43. 2010
  2. pmc The role of stereotactic radiosurgery in the management of patients with newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline
    Mark E Linskey
    Department of Neurosurgery, University of California Irvine Medical Center, Orange, CA, USA
    J Neurooncol 96:45-68. 2010
  3. pmc The role of whole brain radiation therapy in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline
    Laurie E Gaspar
    Department of Radiation Oncology, University of Colorado Denver, Denver, CO, USA
    J Neurooncol 96:17-32. 2010
  4. pmc The role of retreatment in the management of recurrent/progressive brain metastases: a systematic review and evidence-based clinical practice guideline
    Mario Ammirati
    Department of Neurosurgery, Ohio State University Medical Center, Columbus, OH, USA
    J Neurooncol 96:85-96. 2010
  5. pmc Increased chemotactic migration and growth in heparanase-overexpressing human U251n glioma cells
    Xin Hong
    Department of Neurology, Henry Ford Health Science Center, Detroit, MI, USA
    J Exp Clin Cancer Res 27:23. 2008
  6. pmc The role of prophylactic anticonvulsants in the management of brain metastases: a systematic review and evidence-based clinical practice guideline
    Tom Mikkelsen
    Department of Neurology, Henry Ford Health System, Detroit, MI, USA
    J Neurooncol 96:97-102. 2010
  7. pmc Intracellular free calcium mediates glioma cell detachment and cytotoxicity after photodynamic therapy
    Xin Hong
    Department of Neurosurgery, Henry Ford Hospital, Detroit, MI 48202, USA
    Lasers Med Sci 24:777-86. 2009
  8. pmc The role of emerging and investigational therapies for metastatic brain tumors: a systematic review and evidence-based clinical practice guideline of selected topics
    Jeffrey J Olson
    Department of Neurosurgery, Emory University School of Medicine, Atlanta, GA, USA
    J Neurooncol 96:115-42. 2010
  9. pmc The role of steroids in the management of brain metastases: a systematic review and evidence-based clinical practice guideline
    Timothy C Ryken
    Department of Neurosurgery, Iowa Spine and Brain Institute, Iowa City, IA, USA
    J Neurooncol 96:103-14. 2010
  10. pmc Combination therapy with antiangiogenic treatment and photodynamic therapy for the nude mouse bearing U87 glioblastoma
    Feng Jiang
    Department of Neurology, Henry Ford Hospital, Detroit, MI, USA
    Photochem Photobiol 84:128-37. 2008

Collaborators

Detail Information

Publications24

  1. pmc The role of surgical resection in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline
    Steven N Kalkanis
    Department of Neurosurgery, Henry Ford Health System, 2799 West Grand Blvd, K 11, Detroit, MI 48202, USA
    J Neurooncol 96:33-43. 2010
    ..There is insufficient evidence to make a recommendation for patients with poor performance scores, advanced systemic disease, or multiple brain metastases...
  2. pmc The role of stereotactic radiosurgery in the management of patients with newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline
    Mark E Linskey
    Department of Neurosurgery, University of California Irvine Medical Center, Orange, CA, USA
    J Neurooncol 96:45-68. 2010
    ....
  3. pmc The role of whole brain radiation therapy in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline
    Laurie E Gaspar
    Department of Radiation Oncology, University of Colorado Denver, Denver, CO, USA
    J Neurooncol 96:17-32. 2010
    ..Should patients with newly-diagnosed metastatic brain tumors undergo open surgical resection versus whole brain radiation therapy (WBRT) and/or other treatment modalities such as radiosurgery, and in what clinical settings?..
  4. pmc The role of retreatment in the management of recurrent/progressive brain metastases: a systematic review and evidence-based clinical practice guideline
    Mario Ammirati
    Department of Neurosurgery, Ohio State University Medical Center, Columbus, OH, USA
    J Neurooncol 96:85-96. 2010
    ..What evidence is available regarding the use of whole brain radiation therapy (WBRT), stereotactic radiosurgery (SRS), surgical resection or chemotherapy for the treatment of recurrent/progressive brain metastases?..
  5. pmc Increased chemotactic migration and growth in heparanase-overexpressing human U251n glioma cells
    Xin Hong
    Department of Neurology, Henry Ford Health Science Center, Detroit, MI, USA
    J Exp Clin Cancer Res 27:23. 2008
    ..Focal adhesion kinase (FAK) and extracellular signal-regulated kinase 1 (ERK1) signaling were not altered by heparanase-overexpression. These results indicate that heparanase has pleiotropic effects on tumor cells...
  6. pmc The role of prophylactic anticonvulsants in the management of brain metastases: a systematic review and evidence-based clinical practice guideline
    Tom Mikkelsen
    Department of Neurology, Henry Ford Health System, Detroit, MI, USA
    J Neurooncol 96:97-102. 2010
    ..Do prophylactic anticonvulsants decrease the risk of seizure in patients with metastatic brain tumors compared with no treatment?..
  7. pmc Intracellular free calcium mediates glioma cell detachment and cytotoxicity after photodynamic therapy
    Xin Hong
    Department of Neurosurgery, Henry Ford Hospital, Detroit, MI 48202, USA
    Lasers Med Sci 24:777-86. 2009
    ..Our findings indicated that internal calcium store-derived [Ca(2+)](i) plays an important role in PDT-induced enzymatic cell detachment decrease and cytotoxicity. Cell migration may be affected by these changes...
  8. pmc The role of emerging and investigational therapies for metastatic brain tumors: a systematic review and evidence-based clinical practice guideline of selected topics
    Jeffrey J Olson
    Department of Neurosurgery, Emory University School of Medicine, Atlanta, GA, USA
    J Neurooncol 96:115-42. 2010
    ..What evidence is available regarding the emerging and investigational therapies for the treatment of metastatic brain tumors?..
  9. pmc The role of steroids in the management of brain metastases: a systematic review and evidence-based clinical practice guideline
    Timothy C Ryken
    Department of Neurosurgery, Iowa Spine and Brain Institute, Iowa City, IA, USA
    J Neurooncol 96:103-14. 2010
    ..2) comparison of different doses of steroid therapy...
  10. pmc Combination therapy with antiangiogenic treatment and photodynamic therapy for the nude mouse bearing U87 glioblastoma
    Feng Jiang
    Department of Neurology, Henry Ford Hospital, Detroit, MI, USA
    Photochem Photobiol 84:128-37. 2008
    ....
  11. ncbi request reprint The role of targeted therapies in the management of progressive glioblastoma : A systematic review and evidence-based clinical practice guideline
    Jeffrey J Olson
    Department of Neurosurgery, Emory University School of Medicine, Atlanta, GA, USA
    J Neurooncol 118:557-99. 2014
    ..What is the influence of targeted medical therapies on disease control and survival in the adult patient with progressive glioblastoma?..
  12. doi request reprint Heparanase expression is associated with histone modifications in glioblastoma
    Xin Hong
    Department of Neurosurgery, Henry Ford Health System, 2799 W Grand Blvd, Detroit, MI 48202, USA
    Int J Oncol 40:494-500. 2012
    ..Overexpression of both heparanase and NFκB p65 may be the result of excessive histone modifications...
  13. doi request reprint Antitumor treatment using interleukin- 12-secreting marrow stromal cells in an invasive glioma model
    Xin Hong
    Department of Neurosurgery, Henry Ford Health System, Detroit, Michigan 48202, USA
    Neurosurgery 64:1139-46; discussion 1146-7. 2009
    ..In the present study, C57/B16 mice were implanted with the highly invasive Ast11.9-2 glioma cell line to investigate the potential therapeutic effects of interleukin-12 (IL-12)-secreting MSCs...
  14. ncbi request reprint The induction of autophagy by gamma-radiation contributes to the radioresistance of glioma stem cells
    Stephanie L Lomonaco
    Department of Neurosurgery, William and Karen Davidson Laboratory of Cell Signaling and Tumorigenesis, Hermelin Brain Tumor Center, Henry Ford Hospital, Detroit, MI 48202, USA
    Int J Cancer 125:717-22. 2009
    ..Collectively, these results indicate that the induction of autophagy contributes to the radioresistance of these cells and autophagy inhibitors may be employed to increase the sensitivity of CD133+ GSCs to gamma-radiation...
  15. ncbi request reprint It is time to reevaluate the management of patients with brain metastases
    Douglas Kondziolka
    Departments of Neurosurgery and Radiation Oncology, NYU Langone Medical Center, New York, New York Department of Neurosurgery, Henry Ford Health System, Detroit, Michigan Department of Radiation Oncology, University of Maryland, Baltimore, Maryland Department of Medicine Neuro Oncology, Cleveland Clinic Foundation, Cleveland, Ohio Department of Radiation Oncology, Harvard Medical School, Boston, Massachusetts
    Neurosurgery 75:1-9. 2014
    ..The conduct and findings of past clinical research have led to conceptions that affect clinical care yet appear limiting...
  16. ncbi request reprint The role of cytoreductive surgery in the management of progressive glioblastoma : A systematic review and evidence-based clinical practice guideline
    Timothy Charles Ryken
    Department of Neurosurgery, Iowa Spine and Brain Institute, Waterloo, IA, USA
    J Neurooncol 118:479-88. 2014
    ..Should patients with previously diagnosed malignant glioma who are suspected of experiencing progression of the neoplasm process undergo repeat open surgical resection?..
  17. doi request reprint Glioblastoma cell line-derived spheres in serum‑containing medium versus serum-free medium: a comparison of cancer stem cell properties
    Xin Hong
    Department of Neurosurgery, Henry Ford Health System, Detroit, MI 48202, USA
    Int J Oncol 41:1693-700. 2012
    ..U251n cells are distinguished from other tumor cells due to their potential for multilineage differentiation...
  18. doi request reprint Evidence-based guidelines for the management of brain metastases
    Sandeep S Bhangoo
    Department of Neurosurgery, Henry Ford Health System, Hermelin Brain Tumor Center, 2799 West Grand Boulevard, K 11, Detroit, MI 48202, USA
    Neurosurg Clin N Am 22:97-104, viii. 2011
    ..The roles of radiotherapy, surgical resection, and stereotactic radiosurgery along with combination therapies are reviewed. Other topics include the role of chemotherapy, anticonvulsants, steroids, and investigational therapies...
  19. ncbi request reprint The role of imaging in the management of progressive glioblastoma : A systematic review and evidence-based clinical practice guideline
    Timothy Charles Ryken
    Department of Neurosurgery, Iowa Spine and Brain Institute, Waterloo, IA, USA
    J Neurooncol 118:435-60. 2014
    ..Which imaging techniques most accurately differentiate true tumor progression from pseudo-progression or treatment related changes in patients with previously diagnosed glioblastoma?..
  20. ncbi request reprint The role of cytotoxic chemotherapy in the management of progressive glioblastoma : A systematic review and evidence-based clinical practice guideline
    Jeffrey J Olson
    Department of Neurosurgery, Emory University School of Medicine, Atlanta, GA, USA
    J Neurooncol 118:501-55. 2014
    ..What is the impact of cytotoxic chemotherapy on disease control and survival in the adult patient with progressive glioblastoma?..
  21. doi request reprint Raman spectroscopy to distinguish grey matter, necrosis, and glioblastoma multiforme in frozen tissue sections
    Steven N Kalkanis
    Department of Neurosurgery, Hermelin Brain Tumor Center, Henry Ford Health System, 2799 W Grand Blvd, Detroit, MI, 48202, USA
    J Neurooncol 116:477-85. 2014
    ..Future work will develop mapped images of diffuse glioma and neoplastic margins toward development of an intraoperative surgical tool...
  22. doi request reprint Neuro-oncologic applications of exosomes, microvesicles, and other nano-sized extracellular particles
    David D Gonda
    Department of Neurosurgery, University of California, San Diego, CA, USA
    Neurosurgery 72:501-10. 2013
    ..We review the normal physiology of these extracellular vesicles, their pertinence to tumor biology, and directions for research in this field...
  23. doi request reprint Heparanase expression of glioma in human and animal models
    Xin Hong
    Department of Neurosurgery, Henry Ford Health System, Detroit, Michigan 48202, USA
    J Neurosurg 113:261-9. 2010
    ..However, heparanase expression in gliomas has not been well analyzed. To clarify its expression in gliomas, human glioma tissues and glioma animal models were investigated...
  24. ncbi request reprint Decrease of endogenous vascular endothelial growth factor may not affect glioma cell proliferation and invasion
    Xin Hong
    Department of Neurosurgery, Henry Ford Health Science Center, Detroit, MI 48202, USA
    J Exp Ther Oncol 6:219-29. 2007
    ..Our data indicate that the decrease of endogenous VEGF expression may not affect glioma cell proliferation and invasion...