Kenneth A Jenrow

Summary

Affiliation: Henry Ford Hospital
Country: USA

Publications

  1. pmc Increased CSF osmolarity reversibly induces hydrocephalus in the normal rat brain
    Satish Krishnamurthy
    Department of Neurosurgery, Upstate Medical University, Syracuse, NY, 13210, USA
    Fluids Barriers CNS 9:13. 2012
  2. ncbi request reprint Effects of kindling and irradiation on neuronal density in the rat dentate gyrus
    Kenneth A Jenrow
    Epilepsy Research Laboratory, Department of Neurosurgery, Henry Ford Health Sciences Center, Detroit, MI 48202, USA
    Neurosci Lett 371:45-50. 2004
  3. ncbi request reprint Influence of ionizing radiation on the course of kindled epileptogenesis
    Kenneth A Jenrow
    Department of Neurosurgery, Henry Ford Health Sciences Center, Henry Ford Hospital, Detroit, MI 48202, USA
    Brain Res 1094:207-16. 2006
  4. doi request reprint Combined atorvastatin and ramipril mitigate radiation-induced impairment of dentate gyrus neurogenesis
    Kenneth A Jenrow
    Department of Neurosurgery, Henry Ford Health System, Detroit, MI 48202, USA
    J Neurooncol 101:449-56. 2011
  5. pmc Ramipril mitigates radiation-induced impairment of neurogenesis in the rat dentate gyrus
    Kenneth A Jenrow
    Department of Neurosurgery, Henry Ford Hospital, Detroit, Michigan 48202, USA
    Radiat Oncol 5:6. 2010
  6. ncbi request reprint Mitigation of radiation-induced optic neuropathy in rats by ACE inhibitor ramipril: importance of ramipril dose and treatment time
    Samuel Ryu
    Department of Radiation Oncology and Neurosurgery, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, Michigan 48202, USA
    J Neurooncol 82:119-24. 2007
  7. pmc Antioxidant diet supplementation starting 24 hours after exposure reduces radiation lethality
    Stephen L Brown
    Henry Ford Hospital, Department of Radiation Oncology, Detroit, Michigan 48202, USA
    Radiat Res 173:462-8. 2010
  8. ncbi request reprint Modification of radiation injury by ramipril, inhibitor of angiotensin-converting enzyme, on optic neuropathy in the rat
    Jae Ho Kim
    Departments of Radiation Oncology, Neurosurgery and Medicine, Henry Ford Health System, Detroit, MI 48202, USA
    Radiat Res 161:137-42. 2004
  9. pmc Selective inhibition of microglia-mediated neuroinflammation mitigates radiation-induced cognitive impairment
    Kenneth A Jenrow
    a Department of Neurosurgery, Henry Ford Hospital, Detroit, Michigan
    Radiat Res 179:549-56. 2013
  10. doi request reprint Mechanisms of radiation-induced skin injury and implications for future clinical trials
    Jae Ho Kim
    Department of Radiation Oncology, Henry Ford Hospital, Detroit, MI 48202 2689, USA
    Int J Radiat Biol 89:311-8. 2013

Collaborators

  • Jae Ho Kim
  • Samuel Ryu
  • Satish Krishnamurthy
  • Stephen L Brown
  • Lonni Schultz
  • Jie Li
  • Jianguo Liu
  • Andrew Kolozsvary

Detail Information

Publications12

  1. pmc Increased CSF osmolarity reversibly induces hydrocephalus in the normal rat brain
    Satish Krishnamurthy
    Department of Neurosurgery, Upstate Medical University, Syracuse, NY, 13210, USA
    Fluids Barriers CNS 9:13. 2012
    ..abstract:..
  2. ncbi request reprint Effects of kindling and irradiation on neuronal density in the rat dentate gyrus
    Kenneth A Jenrow
    Epilepsy Research Laboratory, Department of Neurosurgery, Henry Ford Health Sciences Center, Detroit, MI 48202, USA
    Neurosci Lett 371:45-50. 2004
    ..Kindling selectively reduced neuronal densities in the dentate granule cell layer, and medial CA3 pyramidal cell layer. Irradiation at 25 Gy, but not at 18 Gy, prevented or reversed this kindling-associated reduction in density...
  3. ncbi request reprint Influence of ionizing radiation on the course of kindled epileptogenesis
    Kenneth A Jenrow
    Department of Neurosurgery, Henry Ford Health Sciences Center, Henry Ford Hospital, Detroit, MI 48202, USA
    Brain Res 1094:207-16. 2006
    ..These results are discussed in relation to mechanisms of seizure- and radiation-induced plasticity...
  4. doi request reprint Combined atorvastatin and ramipril mitigate radiation-induced impairment of dentate gyrus neurogenesis
    Kenneth A Jenrow
    Department of Neurosurgery, Henry Ford Health System, Detroit, MI 48202, USA
    J Neurooncol 101:449-56. 2011
    ....
  5. pmc Ramipril mitigates radiation-induced impairment of neurogenesis in the rat dentate gyrus
    Kenneth A Jenrow
    Department of Neurosurgery, Henry Ford Hospital, Detroit, Michigan 48202, USA
    Radiat Oncol 5:6. 2010
    ..Here we investigate the angiotensin converting enzyme (ACE) inhibitor, ramipril, as a mitigator of radiation injury in this context...
  6. ncbi request reprint Mitigation of radiation-induced optic neuropathy in rats by ACE inhibitor ramipril: importance of ramipril dose and treatment time
    Samuel Ryu
    Department of Radiation Oncology and Neurosurgery, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, Michigan 48202, USA
    J Neurooncol 82:119-24. 2007
    ..This study was to determine the optimum dose and administration time of ramipril for mitigating radiation-induced optic neuropathy...
  7. pmc Antioxidant diet supplementation starting 24 hours after exposure reduces radiation lethality
    Stephen L Brown
    Henry Ford Hospital, Department of Radiation Oncology, Detroit, Michigan 48202, USA
    Radiat Res 173:462-8. 2010
    ..A diet supplemented with antioxidants administered starting 24 h after total-body irradiation improved bone marrow cell survival and mitigated lethality, with a radiation protection factor of approximately 1.18...
  8. ncbi request reprint Modification of radiation injury by ramipril, inhibitor of angiotensin-converting enzyme, on optic neuropathy in the rat
    Jae Ho Kim
    Departments of Radiation Oncology, Neurosurgery and Medicine, Henry Ford Health System, Detroit, MI 48202, USA
    Radiat Res 161:137-42. 2004
    ..The study represents the first demonstration of prophylaxis of radiation injury by a carboxyl-containing ACE inhibitor, providing a pharmacological strategy designed to reduce radiation-induced normal tissue damage...
  9. pmc Selective inhibition of microglia-mediated neuroinflammation mitigates radiation-induced cognitive impairment
    Kenneth A Jenrow
    a Department of Neurosurgery, Henry Ford Hospital, Detroit, Michigan
    Radiat Res 179:549-56. 2013
    ....
  10. doi request reprint Mechanisms of radiation-induced skin injury and implications for future clinical trials
    Jae Ho Kim
    Department of Radiation Oncology, Henry Ford Hospital, Detroit, MI 48202 2689, USA
    Int J Radiat Biol 89:311-8. 2013
    ....
  11. doi request reprint Mechanisms of radiation-induced brain toxicity and implications for future clinical trials
    Jae Ho Kim
    Department of Radiation Oncology, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, MI 48025, USA
    J Neurooncol 87:279-86. 2008
    ..This review highlights preclinical and early clinical data that are translatable for future clinical trials...
  12. ncbi request reprint Plerixafor, a CXCR4 antagonist, mitigates skin radiation-induced injury in mice
    Jae Ho Kim
    Henry Ford Hospital, Department of Radiation Oncology, Detroit, Michigan 48202, USA
    Radiat Res 178:202-6. 2012
    ..This report presents the first observation that CXCR4 antagonist improves both acute and late skin response to radiation exposure...