Naomi Breslau

Summary

Affiliation: Henry Ford Hospital
Country: USA

Publications

  1. ncbi request reprint Epidemiologic studies of trauma, posttraumatic stress disorder, and other psychiatric disorders
    Naomi Breslau
    Department of Psychiatry, Department of Biostatistics and Epidemiology, Henry Ford Health System, One Ford Place, 3A, Detroit, MI 48202 3450, USA
    Can J Psychiatry 47:923-9. 2002
  2. pmc Nicotine dependence and comorbid psychiatric disorders: examination of specific genetic variants in the CHRNA5-A3-B4 nicotinic receptor genes
    Li Shiun Chen
    Department of Psychiatry, Washington University, St Louis, MO 63110, USA
    Drug Alcohol Depend 123:S42-51. 2012
  3. pmc Further evidence for an association between the gamma-aminobutyric acid receptor A, subunit 4 genes on chromosome 4 and Fagerström Test for Nicotine Dependence
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Addiction 104:471-7. 2009
  4. pmc Incorporating age at onset of smoking into genetic models for nicotine dependence: evidence for interaction with multiple genes
    Richard A Grucza
    Department of Psychiatry, Washington University School of Medicine, 660 South Euclid Ave, St Louis, MO 63110, USA
    Addict Biol 15:346-57. 2010
  5. pmc Variants in nicotinic receptors and risk for nicotine dependence
    Laura Jean Bierut
    Department of Psychiatry, Washington University School of Medicine, Box 8134, 660 South Euclid Ave, St Louis, MO 63110, USA
    Am J Psychiatry 165:1163-71. 2008
  6. doi request reprint Gamma-aminobutyric acid receptor genes and nicotine dependence: evidence for association from a case-control study
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Addiction 103:1027-38. 2008
  7. pmc Novel genes identified in a high-density genome wide association study for nicotine dependence
    Laura Jean Bierut
    Department of Psychiatry, Washington University School of Medicine, 660 South Euclid, Box 8134, St Louis, MO 63110, USA
    Hum Mol Genet 16:24-35. 2007
  8. pmc CHRNB3 is more strongly associated with Fagerström test for cigarette dependence-based nicotine dependence than cigarettes per day: phenotype definition changes genome-wide association studies results
    John P Rice
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Addiction 107:2019-28. 2012
  9. pmc Variants in two adjacent genes, EGLN2 and CYP2A6, influence smoking behavior related to disease risk via different mechanisms
    A Joseph Bloom
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA
    Hum Mol Genet 23:555-61. 2014
  10. pmc Rare missense variants in CHRNB4 are associated with reduced risk of nicotine dependence
    Gabe Haller
    Department of Psychiatry, Washington University, St Louis, MO 63110, USA
    Hum Mol Genet 21:647-55. 2012

Detail Information

Publications52

  1. ncbi request reprint Epidemiologic studies of trauma, posttraumatic stress disorder, and other psychiatric disorders
    Naomi Breslau
    Department of Psychiatry, Department of Biostatistics and Epidemiology, Henry Ford Health System, One Ford Place, 3A, Detroit, MI 48202 3450, USA
    Can J Psychiatry 47:923-9. 2002
    ..Trauma victims who do not succumb to PTSD are not at an elevated risk for the subsequent onset of major depression or substance use disorders, compared with unexposed persons...
  2. pmc Nicotine dependence and comorbid psychiatric disorders: examination of specific genetic variants in the CHRNA5-A3-B4 nicotinic receptor genes
    Li Shiun Chen
    Department of Psychiatry, Washington University, St Louis, MO 63110, USA
    Drug Alcohol Depend 123:S42-51. 2012
    ..We examined whether these genetic variants were associated with comorbid disorders and whether comorbid psychiatric disorders modified the genetic risk of nicotine dependence...
  3. pmc Further evidence for an association between the gamma-aminobutyric acid receptor A, subunit 4 genes on chromosome 4 and Fagerström Test for Nicotine Dependence
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Addiction 104:471-7. 2009
    ..In the present report, we extend the previous study by expanding our genotyping efforts significantly for these two genes...
  4. pmc Incorporating age at onset of smoking into genetic models for nicotine dependence: evidence for interaction with multiple genes
    Richard A Grucza
    Department of Psychiatry, Washington University School of Medicine, 660 South Euclid Ave, St Louis, MO 63110, USA
    Addict Biol 15:346-57. 2010
    ..Incorporation of logically chosen interaction parameters, such as AOS, into genetic models of substance use disorders may increase the degree of explained phenotypic variation and constitutes a promising avenue for gene discovery...
  5. pmc Variants in nicotinic receptors and risk for nicotine dependence
    Laura Jean Bierut
    Department of Psychiatry, Washington University School of Medicine, Box 8134, 660 South Euclid Ave, St Louis, MO 63110, USA
    Am J Psychiatry 165:1163-71. 2008
    ....
  6. doi request reprint Gamma-aminobutyric acid receptor genes and nicotine dependence: evidence for association from a case-control study
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Addiction 103:1027-38. 2008
    ....
  7. pmc Novel genes identified in a high-density genome wide association study for nicotine dependence
    Laura Jean Bierut
    Department of Psychiatry, Washington University School of Medicine, 660 South Euclid, Box 8134, St Louis, MO 63110, USA
    Hum Mol Genet 16:24-35. 2007
    ..This work anticipates the future directions of large-scale genome wide association studies with state-of-the-art methodological approaches and sharing of data with the scientific community...
  8. pmc CHRNB3 is more strongly associated with Fagerström test for cigarette dependence-based nicotine dependence than cigarettes per day: phenotype definition changes genome-wide association studies results
    John P Rice
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Addiction 107:2019-28. 2012
    ..e., CPD versus Fagerström test for cigarette dependence (FTCD) score as a measure of nicotine dependence) on genome-wide association studies of nicotine dependence...
  9. pmc Variants in two adjacent genes, EGLN2 and CYP2A6, influence smoking behavior related to disease risk via different mechanisms
    A Joseph Bloom
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA
    Hum Mol Genet 23:555-61. 2014
    ..These results indicate a previously unappreciated novel mechanism behind genome-wide significant associations with cigarette consumption and disease risk unrelated to nicotine metabolism...
  10. pmc Rare missense variants in CHRNB4 are associated with reduced risk of nicotine dependence
    Gabe Haller
    Department of Psychiatry, Washington University, St Louis, MO 63110, USA
    Hum Mol Genet 21:647-55. 2012
    ..01, T91I P = 0.02, R37H P = 0.003), but the largest effect on in vitro receptor activity was seen in the presence of both CHRNB4 T91I and CHRNA3 R37H (P = 2 × 10(-6))...
  11. ncbi request reprint Posttraumatic stress disorder and the incidence of nicotine, alcohol, and other drug disorders in persons who have experienced trauma
    Naomi Breslau
    Department of Psychiatry, Henry Ford Health System, Detroit, MI 48202 3450, USA
    Arch Gen Psychiatry 60:289-94. 2003
    ..We examine whether exposure to traumatic events increases the risk for nicotine dependence or alcohol or other drug use disorders, independent of posttraumatic stress disorder (PTSD)...
  12. pmc A genome-wide association study of alcohol dependence
    Laura J Bierut
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Proc Natl Acad Sci U S A 107:5082-7. 2010
    ..11 and 1.16. Further dissection of the alcoholism phenotype, to disentangle the influence of comorbid substance-use disorders, will be a next step in identifying genetic variants associated with alcohol dependence...
  13. pmc Cigarette smoking reduction and changes in nicotine dependence
    Marc E Mooney
    Department of Psychiatry, University of Minnesota, F 256 2B West, 2450 Riverside Ave, Minneapolis, MN 55454, USA
    Nicotine Tob Res 13:426-30. 2011
    ..The relationship of nicotine dependence (ND) to smoking behavior and cessation has been well characterized. However, little is known about the association between smoking reduction (SR) and ND...
  14. pmc The 10-year risk of verified motor vehicle crashes in relation to physiologic sleepiness
    Christopher Drake
    Sleep Disorders and Research Center, Henry Ford Hospital, 2799 West Grand Blvd, CFP3, Detroit, MI 48202, USA
    Sleep 33:745-52. 2010
    ..The purpose of this study was to determine the risk of DMV documented crashes as a function of physiological sleepiness in a population-based sample...
  15. ncbi request reprint Comorbidity of depression with levels of smoking: an exploration of the shared familial risk hypothesis
    Eric O Johnson
    Department of Psychiatry, Henry Ford Health Sciences Center, Detroit, MI 48202, USA
    Nicotine Tob Res 6:1029-38. 2004
    ..The conflicting findings of the studies that have examined the relationship between smoking and depression may be attributable to differences in definition of the disorders and the methods used to analyze them...
  16. pmc Inclusion of African Americans in genetic studies: what is the barrier?
    Sarah M Hartz
    Department of Psychiatry, School of Medicine, Washington University, St Louis, Missouri 63110, USA
    Am J Epidemiol 174:336-44. 2011
    ..0001). The results of this study suggest that increasing the number of African Americans in genetic databases may be achieved by increasing efforts to locate and contact them...
  17. ncbi request reprint Persistence of cigarette smoking: familial liability and the role of nicotine dependence
    Eric O Johnson
    Department of Psychiatry, Henry Ford Health Sciences Center, Detroit, MI 48202, USA
    Addiction 97:1063-70. 2002
    ..We examined alternative ways that familial liability to persistence, nicotine dependence and smoking persistence may be related...
  18. ncbi request reprint Psychiatric disorders and stages of smoking
    Naomi Breslau
    Department of Psychiatry, Henry Ford Health System, Detroit, Michigan 48202 3450, USA
    Biol Psychiatry 55:69-76. 2004
    ..We examined the role of DSM-III-R psychiatric disorders in predicting the subsequent onset of daily smoking, smokers' progression to nicotine dependence, and the persistence of smoking...
  19. pmc Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs
    Scott F Saccone
    Department of Psychiatry, Box 8134, Washington University School of Medicine, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Hum Mol Genet 16:36-49. 2007
    ..Other genes among the top signals were KCNJ6 and GABRA4. This study represents one of the most powerful and extensive studies of nicotine dependence to date and has found novel risk loci that require confirmation by replication studies...
  20. ncbi request reprint Graphing survival curve estimates for time-dependent covariates
    Lonni R Schultz
    Department of Biostatistics and Research Epidemiology, Henry Ford Health Systems, Detroit, MI, USA
    Int J Methods Psychiatr Res 11:68-74. 2002
    ..Examples of how the two methods can differ for time dependent covariates in Cox proportional hazards regression analysis are presented...
  21. ncbi request reprint Sex differences in the polysomnographic sleep of young adults: a community-based study
    Timothy Roehrs
    Department of Psychiatry and Behavioral Neurosciences, Sleep Disorders and Research Center, School of Medicine, Wayne State University, Henry Ford Hospital, Detroit, MI 48202, USA
    Sleep Med 7:49-53. 2006
    ..Given the higher prevalence of sleep-related breathing disturbance in men, this study assessed sex differences in sleep in a large, non-clinical sample of adults and controlled for primary sleep disorders...
  22. ncbi request reprint Psychiatric morbidity in adult survivors of childhood trauma
    Naomi Breslau
    Department of Psychiatry, Henry Ford Health System, Detroit, MI 48202 3450, USA
    Semin Clin Neuropsychiatry 7:80-8. 2002
    ..However, the retrospective nature of data on child abuse, because of legal and ethical restraints on research on children, is a formidable obstacle to advancing knowledge in this field...
  23. ncbi request reprint Gender differences in trauma and posttraumatic stress disorder
    Naomi Breslau
    Department of Psychiatry, Henry Ford Health System, One Ford Place, 3A, Detroit, MI 48202 3450, USA
    J Gend Specif Med 5:34-40. 2002
    ..Research on posttraumatic stress disorder (PTSD) has focused primarily on Vietnam War veterans. A handful of recent studies have been conducted on samples of the general population...
  24. ncbi request reprint The association of insomnia with anxiety disorders and depression: exploration of the direction of risk
    Eric O Johnson
    Behavioral Health Epidemiology Program, Triangle Institute International, PO Box 12194, 3040 Cornwallis Road, Research Triangle Park, NC, USA
    J Psychiatr Res 40:700-8. 2006
    ..Additionally insomnia may have independent, and potentially etiologically distinct, directional associations with anxiety disorders versus depression...
  25. doi request reprint Race differences in nicotine dependence in the Collaborative Genetic study of Nicotine Dependence (COGEND)
    Zhehui Luo
    Department of Epidemiology, Michigan State University, MI, USA
    Nicotine Tob Res 10:1223-30. 2008
    ..The data support the hypothesis that the relationship between CPD and nicotine dependence as reflected in relapse varies by race, and that Black smokers are dependent at lower levels of CPD than Whites...
  26. ncbi request reprint The structure of posttraumatic stress disorder: latent class analysis in 2 community samples
    Naomi Breslau
    Department of Epidemiology, College of Human Medicine, Michigan State University, B645 West Fee Hall, East Lansing, MI 48824, USA
    Arch Gen Psychiatry 62:1343-51. 2005
    ..Classification of persons exposed to traumatic events into clinically homogeneous groups would facilitate further etiologic and treatment research, as well as research on the relationship of trauma and PTSD with other disorders...
  27. pmc Trauma exposure and posttraumatic stress disorder: a study of youths in urban America
    Naomi Breslau
    Department of Epidemiology, Michigan State University, College of Human Medicine, B645 West Fee Hall, East Lansing 48824, USA
    J Urban Health 81:530-44. 2004
    ....
  28. doi request reprint A second look at prior trauma and the posttraumatic stress disorder effects of subsequent trauma: a prospective epidemiological study
    Naomi Breslau
    Department of Epidemiology, Michigan State University, College of Human Medicine, B645 West Fee Hall, East Lansing, MI 48824, USA
    Arch Gen Psychiatry 65:431-7. 2008
    ..The evidence comes chiefly from retrospective data on earlier events, obtained from trauma-exposed persons with and without PTSD. A generally overlooked major limitation is the failure to assess the PTSD response to the prior trauma...
  29. ncbi request reprint Test of measurement invariance of the FTND across demographic groups: assessment, effect size, and prediction of cessation
    Eric O Johnson
    Behavioral Health Epidemiology, Division of Health, Social, and Economic Research, Research Triangle Institute International, PO Box 12194, 3040 Cornwallis Road, Research Triangle Park, NC 27709 2194, USA
    Drug Alcohol Depend 93:260-70. 2008
    ....
  30. ncbi request reprint Incidence of drug problems in young adults exposed to trauma and posttraumatic stress disorder: do early life experiences and predispositions matter?
    Philip L Reed
    Biomedical Research and Informatics Center, Michigan State University, 100 Conrad Hall, East Lansing, MI 48824 1327, USA
    Arch Gen Psychiatry 64:1435-42. 2007
    ....
  31. ncbi request reprint Smoking and the risk of suicidal behavior: a prospective study of a community sample
    Naomi Breslau
    Department of Epidemiology and Office of the Dean, College of Human Medicine, Michigan State University, East Lansing, USA
    Arch Gen Psychiatry 62:328-34. 2005
    ..A link between cigarette smoking and suicidal behavior has been reported in clinical and epidemiological studies...
  32. ncbi request reprint Saliva cortisol in posttraumatic stress disorder: a community epidemiologic study
    Elizabeth A Young
    Department of Psychiatry and Mental Health Research Institute, University of Michigan, Ann Arbor, Michigan, USA
    Biol Psychiatry 56:205-9. 2004
    ..To address this question, we collected saliva cortisol at home in a subsample of a longitudinal epidemiologic sample...
  33. ncbi request reprint Prenatal smoking exposure, low birth weight, and disruptive behavior disorders
    Joel T Nigg
    Department of Psychology, Michifan State University, 115 Psychology Building, East Lansing, MI 48824 1116, USA
    J Am Acad Child Adolesc Psychiatry 46:362-9. 2007
    ..A key question concerns whether etiological contributors are shared across the broad range of disruptive psychopathology or are partially or largely distinct...
  34. ncbi request reprint Low birth weight as a vulnerability marker for early drug use
    Howard D Chilcoat
    Department of Mental Hygiene, Johns Hopkins University, Baltimore, Maryland 21205, USA
    Exp Clin Psychopharmacol 10:104-12. 2002
    ..These findings suggest that LBW is a useful vulnerability marker for early drug use among boys, independent of the antecedents and sequelae of LBW...
  35. ncbi request reprint Cortisol and catecholamines in posttraumatic stress disorder: an epidemiologic community study
    Elizabeth A Young
    Department of Psychiatry and Mental Health Research Institute, University of Michigan, Ann Arbor, 48109 0720, USA
    Arch Gen Psychiatry 61:394-401. 2004
    ..Prior research has connected posttraumatic stress disorder (PTSD) to increased levels of catecholamines. However, studies of cortisol levels have produced mixed results...
  36. ncbi request reprint Is the association of smoking and depression a recent phenomenon?
    Eric O Johnson
    Division of Health, Social and Economic Research, Research Triangle Institute International, Research Triangle Park, NC 27709 2194, USA
    Nicotine Tob Res 8:257-62. 2006
    ....
  37. ncbi request reprint Sleep in lifetime posttraumatic stress disorder: a community-based polysomnographic study
    Naomi Breslau
    Department of Epidemiology, College of Human Medicine, Michigan State University, East Lansing 48824, USA
    Arch Gen Psychiatry 61:508-16. 2004
    ..Polysomnographic studies conducted on small samples of subjects with specific traumas have yielded conflicting results. We therefore evaluated polysomnographic sleep disturbances in PTSD...
  38. ncbi request reprint Intelligence and other predisposing factors in exposure to trauma and posttraumatic stress disorder: a follow-up study at age 17 years
    Naomi Breslau
    Department of Epidemiology, College of Human Medicine, Michigan State University, East Lansing 48824, USA
    Arch Gen Psychiatry 63:1238-45. 2006
    ..Prospective data on standardized measures of early predispositions would allow a strong test of hypotheses about suspected risk factors of posttraumatic stress disorder (PTSD) and exposure to traumatic events...
  39. ncbi request reprint Childhood antecedents of exposure to traumatic events and posttraumatic stress disorder
    Carla L Storr
    Department of Mental Health, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD, USA
    Am J Psychiatry 164:119-25. 2007
    ..The authors prospectively examined childhood antecedents of exposure to traumatic events to estimate the risk of posttraumatic stress disorder (PTSD) among those exposed to trauma...
  40. ncbi request reprint Partial PTSD versus full PTSD: an empirical examination of associated impairment
    Naomi Breslau
    Department of Epidemiology, Michigan State University, East Lansing, MI 48824, USA
    Psychol Med 34:1205-14. 2004
    ..We examined the extent to which partial PTSD is distinguishable from full DSM-PTSD with respect to level of impairment...
  41. ncbi request reprint Family cohesion and children's behavior problems: a longitudinal investigation
    Victoria C Lucia
    Department of Epidemiology, Michigan State University, College of Human Medicine, East Lansing, 48824, USA
    Psychiatry Res 141:141-9. 2006
    ..The study highlights an important relationship between family cohesion and children's internalizing and attention problems...
  42. ncbi request reprint The lingering academic deficits of low birth weight children
    Naomi Breslau
    Department of Epidemiology, Michigan State University, College of Human Medicine, B645 West Fee Hall, East Lansing, MI 48824, USA
    Pediatrics 114:1035-40. 2004
    ..To estimate the influence of low birth weight (LBW; < or =2500 g) on academic achievement in reading and mathematics in 12th grade in 2 socioeconomically and racially disparate, geographically defined communities...
  43. ncbi request reprint Stability of psychiatric outcomes of low birth weight: a longitudinal investigation
    KIPLING M BOHNERT
    Department of Epidemiology, Michigan State University, College of Human Medicine, B645 West Fee Hall, East Lansing, MI 48824, USA
    Arch Gen Psychiatry 65:1080-6. 2008
    ....
  44. ncbi request reprint Reports of birthweight by adolescents and their mothers: comparing accuracy and identifying correlates
    Victoria C Lucia
    Department of Epidemiology, Michigan State University, College of Human Medicine, East Lansing, MI 48824, USA
    Paediatr Perinat Epidemiol 20:520-7. 2006
    ..While maternal reports of offspring's birthweight are highly accurate across diverse subgroups of the population, adolescent self-reports of birthweight are unlikely to be useful in medical research...
  45. ncbi request reprint Troublesome memories: reflections on the future
    Allan Young
    McGill University, USA
    J Anxiety Disord 21:230-2. 2007
    ..Several papers in this collection direct readers' attention to this fundamental problem. We are pessimistic that their insight will lead to positive results...
  46. ncbi request reprint Epidemiology of DSM-IV insomnia in adolescence: lifetime prevalence, chronicity, and an emergent gender difference
    Eric O Johnson
    Substance Abuse Epi, Prevention, and Risk Behavior, Research Triangle Institute International, Research Triangle Park, NC 27709 2194, USA
    Pediatrics 117:e247-56. 2006
    ....
  47. ncbi request reprint The clinical significance criterion in DSM-IV post-traumatic stress disorder
    Naomi Breslau
    Department of Epidemiology, Michigan State University, College of Human Medicine, East Lansing, MI 48824, USA
    Psychol Med 37:1437-44. 2007
    ..The impact of the clinical significance criterion on the lifetime prevalence of PTSD among civilian victims of traumatic events has not been evaluated...
  48. ncbi request reprint Commentary: Maternal smoking during pregnancy: hazard for what?
    Naomi Breslau
    Department of Epidemiology, Michigan State University, B645 West Fee Hall, East Lansing, MI 48824, USA
    Int J Epidemiol 36:832-3. 2007
  49. ncbi request reprint Gender differences in the sensitivity to posttraumatic stress disorder: An epidemiological study of urban young adults
    Naomi Breslau
    Department of Epidemiology, Michigan State University, East Lansing, MI 48824, USA
    J Abnorm Psychol 116:607-11. 2007
    ..These findings suggest that assaultive violence elicits women's PTSD response directly and by sensitizing them to the effects of subsequent traumatic events of lesser magnitude...
  50. ncbi request reprint Does virtual trauma cause posttraumatic stress disorder?
    Richard J McNally
    Department of Psychology, Harvard University, Cambridge, MA 02138, USA
    Am Psychol 63:282-3; discussion 283-5. 2008
  51. ncbi request reprint Maternal smoking during pregnancy and offspring IQ
    Naomi Breslau
    Department of Epidemiology, Michigan State University, College of Human Medicine, East Lansing, MI 48824, USA
    Int J Epidemiol 34:1047-53. 2005
    ..Maternal smoking in pregnancy lowers birthweight. It is unclear, however, whether smoking during pregnancy lowers offspring IQ, and, if it does, whether it is through the smoking effect on fetal growth...
  52. ncbi request reprint Post-traumatic stress disorder
    Naomi Breslau
    N Engl J Med 346:1495-8; author reply 1495-8. 2002