J H Greist

..This article describes methodological factors that can confound study outcomes and discusses the potential for interactive voice response (IVR) technology to address some of these problems...

..This study compared the value of computer-guided behavior therapy value with that of clinician-guided behavior therapy and systematic relaxation as a control treatment...

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..There is a need for further study and greater awareness among primary health care providers about the prevalence and treatment of social anxiety disorder...

..The authors determined the costs associated with generalized social anxiety disorder in a managed care setting...

..Such IVR technology may provide a cost-effective bridge to the "digital divide" existing among elderly, lower socioeconomic status, and rural populations underrepresented as computer and Internet users...

..This study investigated the sensitivity and specificity of a computer-automated telephone system to evaluate cognitive impairment in elderly callers to identify signs of early dementia...

..9%) and placebo (16.7%) (P=0.905). Only one patient from each group discontinued due to adverse events [sinus infection (St John's wort); confusion (placebo)]. The results fail to support the efficacy of St John's wort for OCD...

..This study assessed the impact of specific instructions designed to decrease risk of dermatologic reactions, including nonserious rash, during initiation of and early treatment with lamotrigine in patients with bipolar I disorder...

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..The purpose of this non-inferiority study was to compare the speed of onset of antidepressant efficacy for duloxetine (a dual serotonin and norepinephrine reuptake inhibitor) and escitalopram (a selective serotonin reuptake inhibitor)...

..The current study was designed to evaluate the validity of obtaining CSFQ data using interactive voice response (IVR) technology...

..Such assessments might benefit routine clinical care and large-scale, longitudinal research in the future, but will require additional research over longer periods...

..Overall, the 1-year results support the need for accessible and anonymous resources for individuals concerned about dementia...

..To compare the effects of starting doses of duloxetine taken with or without food on tolerability and efficacy in patients with major depressive disorder (MDD)...

..In light of the chronicity and disability associated with social phobia, as well as the high relapse rate after short-term therapy, it is recommended that effective treatment be continued for at least 12 months...

..Long-term efficacy and ease of use are important considerations in treatment selection, as maintenance treatment is recommended for at least 12-24 months, and in some cases, indefinitely...

..Further, pharmacotherapy for a minimum of 1-2 years is recommended before very gradual withdrawal may be considered...

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..CONCLUSIONS: The WSAS is a simple, reliable and valid measure of impaired functioning. It is a sensitive and useful outcome measure offering the potential for readily interpretable comparisons across studies and disorders...

..Existing treatments need to be refined and/or new treatments developed to improve these patients' adherence and response to treatment...

..Fluoxetine failed to separate from placebo in this trial. It is unknown whether a larger dose for longer duration would have yielded separation from placebo. A higher than usual placebo response rate was found...

..An adolescent version of the QIDS (QIDS-A-IVR) was created using speaker-independent voice recognition technology. An informant version, QIDS-P-IVR, collects ratings from parents or other knowledgeable adults...

..We examined the efficacy and tolerability associated with a switch from a selective serotonin reuptake inhibitor (SSRI) or venlafaxine to duloxetine...

..Clinicians rated the severity of subjects' sadness and pessimistic thoughts lower than subjects self-report. The data obtained in this pilot study provide support for the equivalence between the clinician and IVR versions of the MADRS...

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