Research Topics
| Alan J GelenbergSummaryAffiliation: Healthcare Technology Systems Country: USA Publications
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Detail Information
Publications
The history and current state of antidepressant clinical trial design: a call to action for proof-of-concept studiesAlan J Gelenberg
Healthcare Technology Systems, 7617 Mineral Point Rd, Suite 300, Madison, WI 53717, USA
J Clin Psychiatry 69:1513-28. 2008..With this in mind, a group of experts was convened under the auspices of the University of Arizona Department of Psychiatry and Best Practice Project Management, Inc...
Using assessment tools to screen for, diagnose, and treat major depressive disorder in clinical practiceAlan J Gelenberg
Healthcare Technology Systems, Inc, Department of Psychiatry, University of Wisconsin School of Medicine and Public Health, Madison, USA
J Clin Psychiatry 71:e01. 2010..Assessment tools are available in many languages. Treatment algorithms can rationalize decision making, and collaborative care can speed and enhance treatment results...
Randomized, placebo-controlled trial of nefazodone maintenance treatment in preventing recurrence in chronic depressionAlan J Gelenberg
Department of Psychiatry, Health Sciences Center, University of Arizona, PO Box 245002, Tucson, AZ 85724-5002, USA
Biol Psychiatry 54:806-17. 2003..8%). Somnolence was significantly greater among the patients taking active medication (15.4%), compared with placebo (4.6%). CONCLUSIONS: Nefazodone is well-tolerated and is an effective maintenance therapy for chronic forms of MDD...
Chronic forms of major depression are still undertreated in the 21st century: systematic assessment of 801 patients presenting for treatmentJames H Kocsis
Department of Psychiatry, Weill Cornell Medical Center, 525 East 68th Street, New York, NY 10021, USA
J Affect Disord 110:55-61. 2008..These results and the consistency of similar results over time point to the dire need for patient and provider education regarding the signs and symptoms of depression and its treatment...
Cognitive behavioral analysis system of psychotherapy and brief supportive psychotherapy for augmentation of antidepressant nonresponse in chronic depression: the REVAMP TrialJames H Kocsis
Department of Psychiatry, Weill Cornell Medical College, 1300 York Ave, New York, NY 10065, USA
Arch Gen Psychiatry 66:1178-88. 2009..Previous studies have found that few chronically depressed patients remit with antidepressant medications alone...
Self-reported depressive symptom measures: sensitivity to detecting change in a randomized, controlled trial of chronically depressed, nonpsychotic outpatientsA John Rush
Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9086, USA
Neuropsychopharmacology 30:405-16. 2005..Global patient ratings such as the PGI-I, as opposed to specific item-based ratings, provide less valid findings...
Treatment of antidepressant-associated sexual dysfunction with sildenafil: a randomized controlled trialH George Nurnberg
Department of Psychiatry, Health Sciences Center, University of New Mexico School of Medicine, 2400 Tucker NE, Albuquerque, NM 87131 5288, USA
JAMA 289:56-64. 2003..Sexual dysfunction is a common adverse effect of antidepressants that frequently results in treatment noncompliance...
Prevention of recurrent episodes of depression with venlafaxine ER in a 1-year maintenance phase from the PREVENT StudyJames H Kocsis
Department of Psychiatry, Weill Cornell Medical College, New York, NY 10012, USA
J Clin Psychiatry 68:1014-23. 2007..To test the long-term efficacy and safety of venlafaxine extended-release (ER) in preventing recurrence in patients with major depression...
REVAMP - Research Evaluating the Value of Augmenting Medication with Psychotherapy: rationale and designMadhukar H Trivedi
Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA
Psychopharmacol Bull 41:5-33. 2008....
The state of knowledge of chronic depressionAlan J Gelenberg
Department of Psychiatry, Arizona Health Sciences Center, Tucson, AZ, USA
J Clin Psychiatry 67:179-84. 2006
Report by the ACNP Task Force on response and remission in major depressive disorderA John Rush
Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9086, USA
Neuropsychopharmacology 31:1841-53. 2006..Research to evaluate these recommendations empirically is needed...
Sexual function and satisfaction in the treatment of chronic major depression with nefazodone, psychotherapy, and their combinationJohn Zajecka
Department of Psychiatry, Rush-Presbyterian-St. Luke's Medical Center, 1725 W. Harrison Street, Suite 955, Chicago, IL 60612, USA
J Clin Psychiatry 63:709-16. 2002..Treatment with nefazodone, CBASP, and combined treatment improved sexual interest/satisfaction, with greatest improvement observed with combined treatment...
A review of the current guidelines for depression treatmentAlan J Gelenberg
Department of Psychiatry, Penn State College of Medicine, Hershey, Pennsylvania, USA
J Clin Psychiatry 71:e15. 2010..Despite progress made during the last decade, no major breakthroughs in the treatment of depression have occurred, and genetic testing developments allowing for personalized care remain the goal of research...
The prevalence and impact of depressionAlan J Gelenberg
Healthcare Technology Systems, Inc, Madison, Wisconsin, USA
J Clin Psychiatry 71:e06. 2010..To combat these negative consequences, clinicians need to be as steadfast as ever to control this disorder and help patients lead symptom-free lives...
Matching the bipolar patient and the mood stabilizerAlan J Gelenberg
Department of Psychiatry, Arizona Health Sciences Center, Tucson, Arizona 85724 5002, USA
Ann Clin Psychiatry 15:203-16. 2003..Randomized, controlled studies in bipolar populations are needed to further characterize optimal matching of patient and medication...
Efficacy of sertraline in prevention of depression recurrence in older versus younger adults with diabetesMonique M Williams
Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
Diabetes Care 30:801-6. 2007..A secondary analysis was performed to assess this effect in younger and older subsets of patients...
Trends in the use of antidepressants in a national sample of commercially insured pediatric patients, 1998 to 2002Thomas Delate
Express Scripts, Inc, Maryland Heights, Missouri 63043, USA
Psychiatr Serv 55:387-91. 2004..The aim of this study was to estimate the prevalence of use of prescription antidepressants among children and adolescents by using nationwide data and to examine trends in use from 1998 to 2002...
Performance improvement CME: improving outcomes in depressionAlan J Gelenberg
Department of Psychiatry, Penn State College of Medicine, Hershey, Pennsylvania, USA
J Clin Psychiatry 71:e19. 2010..This PI CME focuses on improving the detection and initial treatment of depression, enhancing patients' treatment response, and preventing relapse and recurrence...
Feasibility and validation of a computer-automated Columbia-Suicide Severity Rating Scale using interactive voice response technologyJames C Mundt
Healthcare Technology Systems, Inc, 7617 Mineral Point Road, Ste 300, Madison, WI 53717, USA
J Psychiatr Res 44:1224-8. 2010....
Double-blind switch study of imipramine or sertraline treatment of antidepressant-resistant chronic depressionMichael E Thase
Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, 3811 O Hara St, Pittsburgh, PA 15213, USA
Arch Gen Psychiatry 59:233-9. 2002..Although various strategies have been proposed to treat antidepressant nonresponders, little controlled research has been published that examines prospectively the use of switching to an alternate antidepressant...
Metabolic effects of treatment with atypical antipsychoticsJohn M Kane
Department of Psychiatry, The Zucker Hillside Hospital, Glen Oaks, NY, USA
J Clin Psychiatry 65:1447-55. 2004
Depression, antidepressant therapies, and erectile dysfunction: clinical trials of sildenafil citrate (Viagra) in treated and untreated patients with depressionH George Nurnberg
Department of Psychiatry, Health Sciences Center, University of New Mexico School of Medicine, Albuquerque, New Mexico 87131 5286, USA
Urology 60:58-66. 2002..Given the complex interrelations among ED, depression, and other comorbid conditions, the key to proper management is a comprehensive evaluation, including sexual function, and an accurate differential diagnosis...
Smoking cessation in patients with psychiatric disordersAlan J Gelenberg
Department of Psychiatry, University of Arizona, Tucson, USA
J Clin Psychiatry 68:1404-10. 2007
Depression symptomatology and neurobiologyAlan J Gelenberg
Healthcare Technology Systems, Inc, Madison, Wisconsin, USA
J Clin Psychiatry 71:e02. 2010..Neuroimaging, pharmacology, and genomics are among the sources of information that have contributed to theories about the pathophysiology of MDD and may lead to truly personalized medicine in the future...
Alternatives to lithium and divalproex in the maintenance treatment of bipolar disorderMukund Gnanadesikan
Department of Psychiatry, University of Arizona, Tuscon 85724, USA
Bipolar Disord 5:203-16. 2003..CONCLUSIONS: Other than lithium, there are few robust double-blind data to support the use of a variety of agents in the maintenance phase. However, uncontrolled data suggest that a number of agents merit further study...
Sequential catecholamine and serotonin depletion in mirtazapine-treated depressed patientsPedro L Delgado
Department of Psychiatry, Case Western Researve University School of Medicine, Cleveland, OH 44106 5080, USA
Int J Neuropsychopharmacol 5:63-6. 2002..Mood response to tryptophan or catecholamine depletion is dependent on the pharmacological properties of the antidepressant being taken during depletion...
Optimizing depression treatment to increase the likelihood of remissionAlan J Gelenberg
Department of Psychiatry, Penn State College of Medicine, Hershey, Pennsylvania, USA
J Clin Psychiatry 71:e22. 2010....
