Peter Hauser

Summary

Country: USA

Publications

  1. ncbi Neuropsychiatric side effects of HCV therapy and their treatment: focus on IFN alpha-induced depression
    Peter Hauser
    Oregon Health Science University, and Behavioral Health and Clincial Neurosciences Division, Portland VA Medical Center, 97239, USA
    Gastroenterol Clin North Am 33:S35-50. 2004
  2. doi Vulnerability to somatic symptoms of depression during interferon-alpha therapy for hepatitis C: a 16-week prospective study
    Jennifer M Loftis
    Research and Development Service, Portland VA Medical Center, Portland, OR, USA
    J Psychosom Res 74:57-63. 2013
  3. pmc Antiviral completion rates and sustained viral response in hepatitis C patients with and without preexisting major depressive disorder
    Peter Hauser
    Northwest Hepatitis C Resource Center, Portland VA Medical Center, Portland, OR 97202, USA
    Psychosomatics 50:500-5. 2009
  4. pmc The influence of antiviral therapy on psychiatric symptoms among patients with hepatitis C and schizophrenia
    Marilyn Huckans
    Northwest Hepatitis C Resource Center, Portland VA Medical Center, Portland, OR, USA
    Antivir Ther 15:111-9. 2010
  5. pmc Interferon alpha therapy for hepatitis C: treatment completion and response rates among patients with substance use disorders
    Marilyn S Huckans
    Northwest Hepatitis C Resource Center, Portland VA Medical Center, Portland, USA
    Subst Abuse Treat Prev Policy 2:4. 2007
  6. pmc Prophylactic antidepressant treatment in patients with hepatitis C on antiviral therapy: a double-blind, placebo-controlled trial
    Benjamin J Morasco
    Behavioral Health and Clinical Neurosciences Division, Portland VA Medical Center, Portland, OR 97239, USA
    Psychosomatics 51:401-8. 2010
  7. pmc Predictors of pain intensity and pain functioning in patients with the hepatitis C virus
    Benjamin J Morasco
    Northwest Hepatitis C Resource Center and Mental Health and Clinical Neurosciences Division, Portland VA Medical Center, Portland, OR 97239, USA
    Gen Hosp Psychiatry 32:413-8. 2010
  8. doi Screening for depression in patients with hepatitis C using the Beck Depression Inventory-II: do somatic symptoms compromise validity?
    Alexander L Patterson
    Mental Health and Clinical Neurosciences Division, Portland VA Medical Center, Portland, OR, USA
    Gen Hosp Psychiatry 33:354-62. 2011
  9. doi Hepatitis C testing and infection rates in bipolar patients with and without comorbid substance use disorders
    Annette M Matthews
    Northwest Hepatitis C Resource Center, and Behaviorual Health and Clinical Neurosciences Division, Portland VA Medical Center, Portland, OR 97202, USA
    Bipolar Disord 10:266-70. 2008
  10. ncbi Relapse to opioid use after treatment of chronic hepatitis C with pegylated interferon and ribavirin
    Annette M Matthews
    Portland VA Medical Center, 3710 S W U S Veteran Hospital Rd, P O Box 1035 V3MHC, Portland, OR 97202, USA
    Am J Psychiatry 163:1342-7; quiz 1479. 2006

Detail Information

Publications42

  1. ncbi Neuropsychiatric side effects of HCV therapy and their treatment: focus on IFN alpha-induced depression
    Peter Hauser
    Oregon Health Science University, and Behavioral Health and Clincial Neurosciences Division, Portland VA Medical Center, 97239, USA
    Gastroenterol Clin North Am 33:S35-50. 2004
    ....
  2. doi Vulnerability to somatic symptoms of depression during interferon-alpha therapy for hepatitis C: a 16-week prospective study
    Jennifer M Loftis
    Research and Development Service, Portland VA Medical Center, Portland, OR, USA
    J Psychosom Res 74:57-63. 2013
    ..e., cognitive-affective and somatic) in Veterans with hepatitis C viral infection (HCV) before and during interferon-alpha (IFN) based antiviral therapy...
  3. pmc Antiviral completion rates and sustained viral response in hepatitis C patients with and without preexisting major depressive disorder
    Peter Hauser
    Northwest Hepatitis C Resource Center, Portland VA Medical Center, Portland, OR 97202, USA
    Psychosomatics 50:500-5. 2009
    ..Despite evidence suggesting that the majority of patients with hepatitis C virus (HCV) have psychiatric and substance use disorders, patients with these comorbidities have historically been excluded from antiviral therapy for HCV...
  4. pmc The influence of antiviral therapy on psychiatric symptoms among patients with hepatitis C and schizophrenia
    Marilyn Huckans
    Northwest Hepatitis C Resource Center, Portland VA Medical Center, Portland, OR, USA
    Antivir Ther 15:111-9. 2010
    ..The aim of this study was to determine whether antiviral therapy is associated with higher rates of psychiatric symptoms in patients with schizophrenia (SCHZ)...
  5. pmc Interferon alpha therapy for hepatitis C: treatment completion and response rates among patients with substance use disorders
    Marilyn S Huckans
    Northwest Hepatitis C Resource Center, Portland VA Medical Center, Portland, USA
    Subst Abuse Treat Prev Policy 2:4. 2007
    ....
  6. pmc Prophylactic antidepressant treatment in patients with hepatitis C on antiviral therapy: a double-blind, placebo-controlled trial
    Benjamin J Morasco
    Behavioral Health and Clinical Neurosciences Division, Portland VA Medical Center, Portland, OR 97239, USA
    Psychosomatics 51:401-8. 2010
    ..Approximately one-third of patients undergoing interferon-α (IFN-α) therapy for treatment of the hepatitis C virus (HCV) develop major depression, which decreases functioning and may lead to the reduction or discontinuation of treatment...
  7. pmc Predictors of pain intensity and pain functioning in patients with the hepatitis C virus
    Benjamin J Morasco
    Northwest Hepatitis C Resource Center and Mental Health and Clinical Neurosciences Division, Portland VA Medical Center, Portland, OR 97239, USA
    Gen Hosp Psychiatry 32:413-8. 2010
    ..To examine the relationships among biological and psychological variables with pain intensity and pain functioning in patients with the hepatitis C virus (HCV)...
  8. doi Screening for depression in patients with hepatitis C using the Beck Depression Inventory-II: do somatic symptoms compromise validity?
    Alexander L Patterson
    Mental Health and Clinical Neurosciences Division, Portland VA Medical Center, Portland, OR, USA
    Gen Hosp Psychiatry 33:354-62. 2011
    ..The objective of the study was to evaluate the validity of the Beck Depression Inventory-II (BDI-II) when used to measure depression in patients with hepatitis C virus (HCV)...
  9. doi Hepatitis C testing and infection rates in bipolar patients with and without comorbid substance use disorders
    Annette M Matthews
    Northwest Hepatitis C Resource Center, and Behaviorual Health and Clinical Neurosciences Division, Portland VA Medical Center, Portland, OR 97202, USA
    Bipolar Disord 10:266-70. 2008
    ..Our hypothesis was that HCV antibody testing rates and HCV prevalence would be higher in the BD, SUD, and DD groups than the control group...
  10. ncbi Relapse to opioid use after treatment of chronic hepatitis C with pegylated interferon and ribavirin
    Annette M Matthews
    Portland VA Medical Center, 3710 S W U S Veteran Hospital Rd, P O Box 1035 V3MHC, Portland, OR 97202, USA
    Am J Psychiatry 163:1342-7; quiz 1479. 2006
  11. pmc The cognitive effects of hepatitis C in the presence and absence of a history of substance use disorder
    Marilyn Huckans
    Northwest Hepatitis C Resource Center, Portland VA Medical Center, Portland, Oregon 97239, USA
    J Int Neuropsychol Soc 15:69-82. 2009
    ..Results indicate that chronic HCV is associated with cognitive impairment in the absence of a history of SUD. The most robust deficits appear to be in verbal learning and reasoning/mental flexibility. (JINS, 2009, 15, 69-82.)...
  12. ncbi Administration of pegylated interferon-alpha-2a or -2b does not induce sickness behavior in Lewis rats
    Jennifer M Loftis
    Behavioral Health and Clinical Neurosciences Division, Portland VA Medical Center, 3710 SW US Veteran s Hospital Road, Portland, OR 97239, USA
    Psychoneuroendocrinology 31:1289-94. 2006
    ..Collectively, our data suggest that Lewis rats are likely not a useful model to study IFN-induced depression...
  13. doi Pain, substance use disorders and opioid analgesic prescription patterns in veterans with hepatitis C
    Ashlee J Whitehead
    Northwest Hepatitis C Resource Center, Portland, OR, USA
    J Pain Symptom Manage 36:39-45. 2008
    ..13.4 days, P<0.001). These data demonstrate that pain and SUD diagnoses were common among HCV+ patients, and that opioids were frequently prescribed. Co-occurring SUD was not associated with indicators of prescription opioid misuse...
  14. doi Psychiatric and substance use disorders comorbidities in veterans with hepatitis C virus and HIV coinfection
    Bret E Fuller
    Mental Health Division, Portland Veterans Affairs Medical Center, Portland, Oregon 97210, USA
    Curr Opin Psychiatry 22:401-8. 2009
    ..This review covers timely research relative to comorbid conditions that are common in this population including psychiatric diagnoses, substance use disorders and neurocognitive problems...
  15. ncbi Psychiatric management of the hepatitis C patient
    Muhamad Aly Rifai
    Northwest Hepatitis C Resource Center, Portland VA Medical Center, Behavioral Health and Clinical Neurosciences Division, PO Box 1034 P3MHADM, Portland, OR 97239, USA
    Curr Treat Options Gastroenterol 9:508-19. 2006
    ..In this review, we discuss the process of pretreatment assessment of patients with HCV and psychiatric illness and specifically address IFN- and RBV-induced depression in patients receiving HCV treatment...
  16. pmc Antiviral therapy completion and response rates among hepatitis C patients with and without schizophrenia
    Marilyn Huckans
    Department of Psychiatry, Oregon Health and Science University, Portland, Oregon, USA
    Schizophr Bull 36:165-72. 2010
    ..Despite disproportionately high rates of hepatitis C (HCV) among patients with severe mental illness, to date, there is scant empirical data available regarding antiviral therapy outcomes within this population...
  17. ncbi Management of hepatitis C disease among VA patients with schizophrenia and substance use disorders
    Marilyn S Huckans
    Northwest Hepatitis C Resource Center, Portland Veterans Affairs Medical Center, and Department of Psychiatry at Oregon Health and Science University 97239, USA
    Psychiatr Serv 57:403-6. 2006
    ....
  18. ncbi Treatment outcomes in depression: comparison of remote treatment through telepsychiatry to in-person treatment
    Paul E Ruskin
    VA Capitol Network Mental Illness Research Education and Clinical Center, Baltimore, MD, USA
    Am J Psychiatry 161:1471-6. 2004
    ....
  19. pmc Depressive symptoms in patients with chronic hepatitis C are correlated with elevated plasma levels of interleukin-1beta and tumor necrosis factor-alpha
    Jennifer M Loftis
    Behavioral Health and Clinical Neurosciences Division, Portland VA Medical Center, Department of Psychiatry, Oregon Health and Science University, Portland, OR 97239, USA
    Neurosci Lett 430:264-8. 2008
    ..Future studies should investigate how inflammatory mediators play a role in the expression of specific depressive symptoms in patients with chronic infection. Patients with HCV represent an interesting model to examine this relationship...
  20. ncbi The phenomenology and treatment of interferon-induced depression
    Jennifer M Loftis
    Behavioral Health and Clinical Neurosciences Division, Portland VA Medical Center, Portland, OR, USA
    J Affect Disord 82:175-90. 2004
    ..Screening and monitoring, ideally using symptom rating scales for depression, and early antidepressant treatment intervention appear necessary to optimize IFN therapy for the majority of patients...
  21. ncbi Association of interferon-alpha-induced depression and improved treatment response in patients with hepatitis C
    Jennifer M Loftis
    Portland VA Medical Center, Behavioral Health and Clinical Neurosciences Division, OR, USA
    Neurosci Lett 365:87-91. 2004
    ..In conclusion, our findings suggest that IFN-alpha-induced MDD may be a predictor of a positive response to IFN-alpha therapy, or an indication of optimal dosing...
  22. ncbi Integrated hepatitis C virus treatment: addressing comorbid substance use disorders and HIV infection
    Marilyn S Huckans
    Northwest Hepatitis C Resource Center, Portland VA Medical Center, Portland, OR 97239, USA
    AIDS 19:S106-15. 2005
    ..To examine hepatitis C virus (HCV) and HIV testing patterns within the Northwest Veterans Integrated Service Network (VISN 20)...
  23. ncbi Hepatitis C treatment of veterans with psychiatric illness
    Muhamad Aly Rifai
    Am J Gastroenterol 101:673-4; author reply 674-5. 2006
  24. ncbi Addressing tri-morbidity (hepatitis C, psychiatric disorders, and substance use): the importance of routine mental health screening as a component of a comanagement model of care
    Marian Fireman
    Northwest Hepatitis C Resource Center and Behavioral Health and Neurosciences Division, Portland, OR 97239, USA
    Clin Infect Dis 40:S286-91. 2005
    ..Recent studies suggest that most patients with hepatitis C virus (HCV) infection commonly present to medical clinics with active psychiatric and substance use disorders. However, routine screening for these disorders is generally not done...
  25. doi Appreciation of research information in patients with bipolar disorder
    Sahana Misra
    Portland Veterans Affairs Medical Center, Portland, OR, USA
    Bipolar Disord 10:635-46. 2008
    ..We compared the abilities of euthymic and manic bipolar patients to appreciate and make voluntary decisions regarding research participation...
  26. pmc Co-occurring Hepatitis C, substance use, and psychiatric illness: treatment issues and developing integrated models of care
    Diana L Sylvestre
    Department of Medicine, University of California, San Francisco, California, USA
    J Urban Health 81:719-34. 2004
    ..This conference report summarizes current data, medical management issues, and strategies discussed...
  27. ncbi Comments on the paper 'The effect of a herbal medicine (Mao-to) for the prevention of interferon-induced psychiatric complications in chronic hepatitis C: a pilot study'
    Jennifer M Loftis
    Hum Psychopharmacol 20:211-2; author reply 213. 2005
  28. ncbi Safety of the treatment of interferon-alpha-induced depression
    Jennifer M Loftis
    Psychosomatics 44:524-6. 2003
  29. ncbi Depression comorbidity and antidepressant use in veterans with chronic hepatitis C: results from a retrospective chart review
    Julie A Nelligan
    Northwest Hepatitis C Resource Center, Behavioral Health and Clinical Neurosciences Division, Portland Department of Veterans Affairs VA Medical Center, Oregon Health and Science University, Portland, Oregon 97207, USA
    J Clin Psychiatry 69:810-6. 2008
    ..In this study we characterize the prevalence and severity of co-morbid depression, as well as antidepressant and other psychotropic prescribing patterns, in a sample of U.S. veterans with HCV...
  30. ncbi A randomized trial of paroxetine to prevent interferon-alpha-induced depression in patients with hepatitis C
    Benjamin J Morasco
    Behavioral Health and Clinical Neurosciences Division, Portland VA Medical Center, Oregon, United States
    J Affect Disord 103:83-90. 2007
    ..This study examined the efficacy of paroxetine in preventing the development of depression during antiviral therapy...
  31. ncbi Can rodents be used to model interferon-alpha-induced depressive symptoms?
    Jennifer M Loftis
    Prog Neuropsychopharmacol Biol Psychiatry 30:1364-5; author reply 1366. 2006
  32. ncbi The association between viral clearance and depression in patients with hepatitis C receiving interferon-alpha and ribavirin
    Jennifer M Loftis
    Brain Behav Immun 19:271-2; author reply 273-4. 2005
  33. ncbi Lamotrigine-associated Stevens-Johnson syndrome after discontinuation of interferon, ribavirin, and filgrastim: a case report
    Annette M Matthews
    J Clin Psychiatry 68:637-8. 2007
  34. ncbi Psychiatric and substance use disorders in individuals with hepatitis C: epidemiology and management
    Jennifer M Loftis
    Department of Psychiatry, Oregon Health and Science University, Portland, Oregon, USA
    Drugs 66:155-74. 2006
    ....
  35. ncbi Interferon-alpha treatment of patients with Hepatitis C: the role of a comprehensive risk-benefit assessment
    Muhamad Aly Rifai
    CNS Drugs 19:719-21; author reply 721-2. 2005
  36. ncbi Strategies to decrease costs of prescribing selective serotonin reuptake inhibitors at a VA Medical Center
    Steven K Dobscha
    Portland Veterans Affairs Medical Center, Oregon 97207, USA
    Psychiatr Serv 54:195-200. 2003
    ..The authors examined the efficacy of a multifaceted intervention designed to contain the cost of prescribing selective serotonin reuptake inhibitors (SSRIs) to inpatients and outpatients served by a Veterans Affairs (VA) medical center...
  37. ncbi Serotonin gene polymorphisms and bipolar I disorder: focus on the serotonin transporter
    Hader A Mansour
    Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA 15213, U S A
    Ann Med 37:590-602. 2005
    ..Our analyses do not support association between SLC6A4 and BDI families. Further studies using sub-groups of BDI are worthwhile...
  38. doi Influence of mood state on capacity to consent to research in patients with bipolar disorder
    Sahana Misra
    Portland Veterans Affairs Medical Center, OR 97239, USA
    Bipolar Disord 10:303-9. 2008
    ..We compared 25 euthymic bipolar and 26 manic bipolar patients in their understanding of three hypothetical studies of varying complexity...
  39. ncbi Effectiveness of adjunctive antidepressant treatment for bipolar depression
    Gary S Sachs
    Bipolar Clinic and Research Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    N Engl J Med 356:1711-22. 2007
    ..Our study was designed to determine whether adjunctive antidepressant therapy reduces symptoms of bipolar depression without increasing the risk of mania...
  40. ncbi Relationship of white matter hyperintensities to cerebrospinal fluid glucose polyol pathway metabolites-a pilot study in treatment-resistant affective disorder patients
    William T Regenold
    Division of Geriatric Psychiatry, Department of Psychiatry, University of Maryland School of Medicine, and Research Service, VA Maryland Healthcare System, Baltimore, MD 21201, USA
    J Affect Disord 85:341-50. 2005
    ....
  41. ncbi Treatment of cytokine-induced depression
    Lucile Capuron
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 1639 Pierce Drive, Suite 4000, Atlanta, GA 30322, USA
    Brain Behav Immun 16:575-80. 2002
    ....
  42. pmc Whole-genome association study of bipolar disorder
    P Sklar
    Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA 02114, USA
    Mol Psychiatry 13:558-69. 2008
    ..Given the heritability of BP disorder, the lack of agreement between studies emphasizes that susceptibility alleles are likely to be modest in effect size and require even larger samples for detection...