E H Zhou

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Mechanical responsiveness of the endothelial cell of Schlemm's canal: scope, variability and its potential role in controlling aqueous humour outflow
    E H Zhou
    Program in Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA
    J R Soc Interface 9:1144-55. 2012
  2. doi request reprint A power-law rheology-based finite element model for single cell deformation
    E H Zhou
    Program in Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115, USA
    Biomech Model Mechanobiol 11:1075-84. 2012
  3. doi request reprint Power-law rheology analysis of cells undergoing micropipette aspiration
    E H Zhou
    Department of Mechanical Engineering, National University of Singapore, Singapore
    Biomech Model Mechanobiol 9:563-72. 2010
  4. pmc Universal behavior of the osmotically compressed cell and its analogy to the colloidal glass transition
    E H Zhou
    Program in Molecular and Integrative Physiological Sciences, Harvard School of Public Health, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 106:10632-7. 2009
  5. ncbi request reprint Mechanical models for living cells--a review
    C T Lim
    Nano Biomechanics Laboratory, Division of Bioengineering and Department of Mechanical Engineering, National University of Singapore, 9 Engineering Drive 1, Singapore 117576, Singapore
    J Biomech 39:195-216. 2006
  6. pmc Biomechanical effects of environmental and engineered particles on human airway smooth muscle cells
    P Berntsen
    Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    J R Soc Interface 7:S331-40. 2010

Collaborators

  • C T Lim
  • A Tsuda
  • M Johnson
  • P Berntsen
  • C Y Park
  • T M Sager
  • T C Donaghey
  • D J Tschumperlin
  • J D Brain
  • J P Butler
  • A M Alencar
  • J Swenson
  • R M Molina
  • E J Millet
  • P Gehr
  • D I Kasahara
  • J J Fredberg
  • B Rothen-Rutishauser
  • T Ericsson

Detail Information

Publications6

  1. pmc Mechanical responsiveness of the endothelial cell of Schlemm's canal: scope, variability and its potential role in controlling aqueous humour outflow
    E H Zhou
    Program in Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA
    J R Soc Interface 9:1144-55. 2012
    ..Although the mechanism and locus of increased outflow resistance remain unclear, these data suggest the SC endothelial cell to be a modulator of outflow resistance...
  2. doi request reprint A power-law rheology-based finite element model for single cell deformation
    E H Zhou
    Program in Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115, USA
    Biomech Model Mechanobiol 11:1075-84. 2012
    ..Taken together, our work leads to more accurate rheological interpretation of micropipette aspiration experiments than previous models and suggests pressure gradient as a potential determinant of cell injury...
  3. doi request reprint Power-law rheology analysis of cells undergoing micropipette aspiration
    E H Zhou
    Department of Mechanical Engineering, National University of Singapore, Singapore
    Biomech Model Mechanobiol 9:563-72. 2010
    ..As such, our results suggest that the application of relatively large pipettes can provide more effective assessment of the bulk material properties as well as support application of power-law rheology to cells in suspension...
  4. pmc Universal behavior of the osmotically compressed cell and its analogy to the colloidal glass transition
    E H Zhou
    Program in Molecular and Integrative Physiological Sciences, Harvard School of Public Health, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 106:10632-7. 2009
    ..Our work provides a means to probe the physical nature of the cytoplasm under compression, and leads to results that are universal across cell type...
  5. ncbi request reprint Mechanical models for living cells--a review
    C T Lim
    Nano Biomechanics Laboratory, Division of Bioengineering and Department of Mechanical Engineering, National University of Singapore, 9 Engineering Drive 1, Singapore 117576, Singapore
    J Biomech 39:195-216. 2006
    ..More realistic mechanical models of living cells can further contribute towards the study of mechanotransduction in cells...
  6. pmc Biomechanical effects of environmental and engineered particles on human airway smooth muscle cells
    P Berntsen
    Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    J R Soc Interface 7:S331-40. 2010
    ..Our results highlight the susceptibility of cellular mechanical function to particulate exposures and suggest that direct exposure of the airway smooth muscle cells to particulates may initiate or aggravate respiratory diseases...