Affiliation: Harvard University
- Adaptive filtering for global interference cancellation and real-time recovery of evoked brain activity: a Monte Carlo simulation studyQuan Zhang
Harvard Medical School, Massachusetts General Hospital, Neural Systems Group, 13th Street, Building 149, Room 2651, Charlestown, Massachusetts 02129, USA
J Biomed Opt 12:044014. 2007..The technique can be performed in real time, an important feature required for applications such as brain activity localization, biofeedback, and potential neuroprosthetic devices...
- Study of near infrared technology for intracranial hematoma detectionQ Zhang
Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia 19104 6089, USA
J Biomed Opt 5:206-13. 2000..Model inhomogeneity tests and animal hematoma tests showed the effectiveness of the improved hematoma detector for intracranial hematoma detection...
- Development of motion resistant instrumentation for ambulatory near-infrared spectroscopyQuan Zhang
Massachusetts General Hospital, Harvard Medical School, Neural Systems Group, Charlestown, Massachusetts 02129, USA
J Biomed Opt 16:087008. 2011..To the best of our knowledge, this is the first report of multiparameter aNIRS monitoring and its application in parabolic flight...
- Adaptive filtering to reduce global interference in evoked brain activity detection: a human subject case studyQuan Zhang
Massachusetts General Hospital, Harvard Medical School, Neural Systems Group, 13th Street, Building 149, Room 2651, Charlestown, Massachusetts 02129, USA
J Biomed Opt 12:064009. 2007..In addition, the results suggested that association between the superficial layer hemodynamics and the total global interference is time-varying...
- Combined optical imaging and mammography of the healthy breast: optical contrast derived from breast structure and compressionQianqian Fang
Massachusetts General Hospital, Charlestown, MA 02148 USA
IEEE Trans Med Imaging 28:30-42. 2009..The optical images from a subset of patients show composite features from both tissue structure and pressure distribution. We present mechanical simulations which further confirm this hypothesis...
- Adaptive filtering to reduce global interference in non-invasive NIRS measures of brain activation: how well and when does it work?Quan Zhang
Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
Neuroimage 45:788-94. 2009....
- Tomographic optical breast imaging guided by three-dimensional mammographyAng Li
Department of Physics, Tufts University, Medford, Massachusetts 02155, USA
Appl Opt 42:5181-90. 2003..We suggest an approach to find the optimal regularization parameters. The presented preliminary clinical result indicates the utility of the method...
- Advances in the application of technology to epilepsy: the CIMIT/NIO Epilepsy Innovation SummitSteven C Schachter
Center for Integration of Medicine and Innovative Technology, Boston, MA, USA
Epilepsy Behav 16:3-46. 2009..This article summarizes the discussions and demonstrates that cross-disciplinary interactions can catalyze collaborations between physicians and engineers to address and solve many of the pressing unmet needs in epilepsy...
- Optimal linear inverse solution with multiple priors in diffuse optical tomographyAng Li
Department of Physics Tufts University, Medford, Massachusetts 02155, USA
Appl Opt 44:1948-56. 2005..Simulations are performed to demonstrate the significant improvement in image quality afforded by combining spatial and spectral priors...
- Reconstructing chromosphere concentration images directly by continuous-wave diffuse optical tomographyAng Li
Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
Opt Lett 29:256-8. 2004..We demonstrate this improvement with simulations and a dynamic blood phantom experiment...
- Coregistered tomographic x-ray and optical breast imaging: initial resultsQuan Zhang
Harvard Medical School, Massachusetts General Hospital, The Martinos Center for Biomedical Imaging, 13th Street, Building 149, Room 2301, Charlestown, Massachusetts 02129, USA
J Biomed Opt 10:024033. 2005..This comparison will ultimately lead to a better understanding of the relationship between the functional contrast afforded by optical imaging and the structural contrast provided by x-ray imaging...
- Depth sensitivity and source-detector separations for near infrared spectroscopy based on the colin27 brain templateGARY E STRANGMAN
Neural Systems Group, Massachusetts General Hospital Harvard Medical School, Charlestown, Massachusetts, United States of America
PLoS ONE 8:e66319. 2013....
- Non-invasive and quantitative near-infrared haemoglobin spectrometry in the piglet brain during hypoxic stress, using a frequency-domain multidistance instrumentD M Hueber
University of Pennsylvania, School of Medicine in Philadelphia, USA
Phys Med Biol 46:41-62. 2001..The origin of this 'effective' background absorption may be real, an artefact caused by the application of a simplified model to a complex sample, or a combination of factors...
- Fluorescence optical diffusion tomographyAdam B Milstein
School of Electrical and Computer Engineering, Purdue University, West Lafayette, Indiana 47907 1285, USA
Appl Opt 42:3081-94. 2003..The effectiveness of the reconstruction algorithm is demonstrated by simulation and by application to experimental data from a tissue phantom containing the fluorescent agent Indocyanine Green...
- Quantitative spectroscopic diffuse optical tomography of the breast guided by imperfect a priori structural informationGregory Boverman
Department of Electrical and Computer Engineering, Northeastern University, 302 Stearns Hall, Boston, MA 02115, USA
Phys Med Biol 50:3941-56. 2005..In addition, we examine the consequences which errors in the breast segmentation have on estimating both the background and inhomogeneity chromophore concentrations...