Mingfeng Zhang

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Pathway analysis for genome-wide association study of basal cell carcinoma of the skin
    Mingfeng Zhang
    Department of Dermatology, Clinical Research Program, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 6:e22760. 2011
  2. doi request reprint A genome-wide association study of severe teenage acne in European Americans
    Mingfeng Zhang
    Department of Dermatology, Clinical Research Program, Brigham and Women s Hospital, and Harvard Medical School, 181 Longwood Avenue, Boston, MA, 02115, USA
    Hum Genet 133:259-64. 2014
  3. pmc Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans
    Mingfeng Zhang
    Clinical Research Program, Department of Dermatology, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Hum Mol Genet 22:2948-59. 2013
  4. pmc Use of tanning beds and incidence of skin cancer
    Mingfeng Zhang
    Brigham and Women s Hospital, Boston, MA, USA
    J Clin Oncol 30:1588-93. 2012
  5. pmc Genetically determined ABCB5 functionality correlates with pigmentation phenotype and melanoma risk
    Jennifer Y Lin
    Department of Dermatology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Biochem Biophys Res Commun 436:536-42. 2013
  6. pmc Integrating pathway analysis and genetics of gene expression for genome-wide association study of basal cell carcinoma
    Mingfeng Zhang
    Clinical Research Program, Department of Dermatology, Harvard Medical School, Brigham and Women s Hospital, Boston, MA 02115, USA
    Hum Genet 131:615-23. 2012
  7. ncbi request reprint Heterogeneity in host risk factors for incident melanoma and non-melanoma skin cancer in a cohort of US women
    Abrar A Qureshi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    J Epidemiol 21:197-203. 2011
  8. pmc PGC-1 coactivators regulate MITF and the tanning response
    Jonathan Shoag
    Cardiovascular Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA
    Mol Cell 49:145-57. 2013
  9. ncbi request reprint Association between Cutaneous Nevi and Breast Cancer in the Nurses' Health Study: A Prospective Cohort Study
    Mingfeng Zhang
    Department of Dermatology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS Med 11:e1001659. 2014
  10. pmc Genetic variation in DNA repair pathway genes and melanoma risk
    Mingfeng Zhang
    Clinical Research Program, Department of Dermatology, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA, USA
    DNA Repair (Amst) 10:111-6. 2011

Collaborators

Detail Information

Publications10

  1. pmc Pathway analysis for genome-wide association study of basal cell carcinoma of the skin
    Mingfeng Zhang
    Department of Dermatology, Clinical Research Program, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 6:e22760. 2011
    ..Recently, a pathway-based approach has been developed to evaluate the cumulative contribution of the functionally related genes for genome-wide association studies (GWASs), which may help utilize GWAS data to a greater extent...
  2. doi request reprint A genome-wide association study of severe teenage acne in European Americans
    Mingfeng Zhang
    Department of Dermatology, Clinical Research Program, Brigham and Women s Hospital, and Harvard Medical School, 181 Longwood Avenue, Boston, MA, 02115, USA
    Hum Genet 133:259-64. 2014
    ..01 (95 % confidence interval = 2.37-6.82). Upon further replication, our findings suggest new genetic basis of acne and may explain the association between acne and cancer risk observed in the epidemiological studies...
  3. pmc Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans
    Mingfeng Zhang
    Clinical Research Program, Department of Dermatology, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Hum Mol Genet 22:2948-59. 2013
    ..0 × 10(-8); P = 6.6 × 10(-7) in the discovery set and P = 3.0 × 10(-3) in the replication set) and rs8015138 upstream of GNG2 (P = 6.6 × 10(-8); P = 5.3 × 10(-7) in the discovery set and P = 0.01 in the replication set). ..
  4. pmc Use of tanning beds and incidence of skin cancer
    Mingfeng Zhang
    Brigham and Women s Hospital, Boston, MA, USA
    J Clin Oncol 30:1588-93. 2012
    ..We sought to evaluate the risk effect of tanning bed use on skin cancers among teenage and young adults. We also expected to determine whether a dose-response relationship was evident...
  5. pmc Genetically determined ABCB5 functionality correlates with pigmentation phenotype and melanoma risk
    Jennifer Y Lin
    Department of Dermatology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Biochem Biophys Res Commun 436:536-42. 2013
    ..Moreover, they provide a first example that functional variation in a prospective cancer stem cell marker can be associated with disease risk for the corresponding malignancy. ..
  6. pmc Integrating pathway analysis and genetics of gene expression for genome-wide association study of basal cell carcinoma
    Mingfeng Zhang
    Clinical Research Program, Department of Dermatology, Harvard Medical School, Brigham and Women s Hospital, Boston, MA 02115, USA
    Hum Genet 131:615-23. 2012
    ..08). Based on the evidence of biological functions of the JAK-STAT pathway on oncogenesis, it is plausible that this pathway is involved in BCC pathogenesis...
  7. ncbi request reprint Heterogeneity in host risk factors for incident melanoma and non-melanoma skin cancer in a cohort of US women
    Abrar A Qureshi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    J Epidemiol 21:197-203. 2011
    ..Melanoma, squamous cell carcinoma (SCC), and basal cell carcinoma (BCC) are 3 types of skin cancer that have distinct biologic characteristics and prognoses. We evaluated phenotypic differences in the risk of these cancers in US women...
  8. pmc PGC-1 coactivators regulate MITF and the tanning response
    Jonathan Shoag
    Cardiovascular Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA
    Mol Cell 49:145-57. 2013
    ..These data identify PGC-1 coactivators as regulators of human tanning...
  9. ncbi request reprint Association between Cutaneous Nevi and Breast Cancer in the Nurses' Health Study: A Prospective Cohort Study
    Mingfeng Zhang
    Department of Dermatology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS Med 11:e1001659. 2014
    ..Cutaneous nevi are suggested to be hormone-related. We hypothesized that the number of cutaneous nevi might be a phenotypic marker of plasma hormone levels and predict subsequent breast cancer risk...
  10. pmc Genetic variation in DNA repair pathway genes and melanoma risk
    Mingfeng Zhang
    Clinical Research Program, Department of Dermatology, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA, USA
    DNA Repair (Amst) 10:111-6. 2011
    ..Further work on fine-mapping and on the functional characterization of this and linked SNPs in this region is required...