Hui Zhang

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint PC-1/PrLZ contributes to malignant progression in prostate cancer
    Hui Zhang
    Laboratory of Molecular Oncology, Institute of Biotechnology, Beijing, P R China
    Cancer Res 67:8906-13. 2007
  2. pmc Electrical impedance myography to assess outcome in amyotrophic lateral sclerosis clinical trials
    Seward B Rutkove
    Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Clin Neurophysiol 118:2413-8. 2007
  3. doi request reprint Antibiotic use and the risk of lung cancer
    Hui Zhang
    Department Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 17:1308-15. 2008
  4. ncbi request reprint A six-month, placebo-controlled trial of D-cycloserine co-administered with conventional antipsychotics in schizophrenia patients
    Donald C Goff
    Schizophrenia Program, Massachusetts General Hospital, Boston, Mass, USA
    Psychopharmacology (Berl) 179:144-50. 2005
  5. ncbi request reprint Glucose metabolism in patients with schizophrenia treated with olanzapine or quetiapine: a frequently sampled intravenous glucose tolerance test and minimal model analysis
    David C Henderson
    Schizophrenia Program, Massachusetts General Hospital, Boston, USA
    J Clin Psychiatry 67:789-97. 2006
  6. ncbi request reprint [The phenotype and function of CD4+ CD25+ regulatory T cells in hepatitis B patients]
    Jun Liang Fu
    Research Center of Biological Therapy, The 302th Hospital of PLA, Beijing 100039, China
    Zhonghua Nei Ke Za Zhi 45:642-5. 2006
  7. ncbi request reprint Trial of celecoxib in amyotrophic lateral sclerosis
    Merit E Cudkowicz
    Neurology Clinical Trials Unit, Massachusetts General Hospital, Harvard Medical School, Boston, 02172, USA
    Ann Neurol 60:22-31. 2006
  8. ncbi request reprint PD-1 up-regulation is correlated with HIV-specific memory CD8+ T-cell exhaustion in typical progressors but not in long-term nonprogressors
    Ji Yuan Zhang
    Institute of Microbiology, Chinese Academy of Sciences, Beijing, China
    Blood 109:4671-8. 2007
  9. ncbi request reprint Increased regulatory T cells correlate with CD8 T-cell impairment and poor survival in hepatocellular carcinoma patients
    Junliang Fu
    Research Center for Biological Therapy, Beijing Institute of Infectious Diseases, Beijing 302 Hospital, Beijing, China
    Gastroenterology 132:2328-39. 2007
  10. ncbi request reprint Increased incidence of deep venous thrombosis in ALS
    M Muddasir Qureshi
    Neurology Clinical Trials Unit, Department of Neurology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Neurology 68:76-7. 2007

Collaborators

Detail Information

Publications37

  1. ncbi request reprint PC-1/PrLZ contributes to malignant progression in prostate cancer
    Hui Zhang
    Laboratory of Molecular Oncology, Institute of Biotechnology, Beijing, P R China
    Cancer Res 67:8906-13. 2007
    ..Inhibiting PC-1 expression may represent a novel therapeutic strategy to delay prostate cancer progression...
  2. pmc Electrical impedance myography to assess outcome in amyotrophic lateral sclerosis clinical trials
    Seward B Rutkove
    Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Clin Neurophysiol 118:2413-8. 2007
    ..This study investigates whether EIM could provide a new outcome measure for use in ALS clinical trials work...
  3. doi request reprint Antibiotic use and the risk of lung cancer
    Hui Zhang
    Department Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 17:1308-15. 2008
    ..Current evidence is insufficient to support or refute a carcinogenic effect of antibiotics...
  4. ncbi request reprint A six-month, placebo-controlled trial of D-cycloserine co-administered with conventional antipsychotics in schizophrenia patients
    Donald C Goff
    Schizophrenia Program, Massachusetts General Hospital, Boston, Mass, USA
    Psychopharmacology (Berl) 179:144-50. 2005
    ..The strongest evidence for efficacy has come from studies using D-cycloserine at a dose of 50 mg/day added to conventional antipsychotics in trials of 8 weeks duration or less...
  5. ncbi request reprint Glucose metabolism in patients with schizophrenia treated with olanzapine or quetiapine: a frequently sampled intravenous glucose tolerance test and minimal model analysis
    David C Henderson
    Schizophrenia Program, Massachusetts General Hospital, Boston, USA
    J Clin Psychiatry 67:789-97. 2006
    ..Much less is known regarding other agents such as quetiapine. The objective of this study was to compare matched olanzapine- and quetiapine-treated schizophrenia patients and normal controls on measures of glucose metabolism...
  6. ncbi request reprint [The phenotype and function of CD4+ CD25+ regulatory T cells in hepatitis B patients]
    Jun Liang Fu
    Research Center of Biological Therapy, The 302th Hospital of PLA, Beijing 100039, China
    Zhonghua Nei Ke Za Zhi 45:642-5. 2006
    ..Our aim was to investigate the frequency, phenotype and function of CD4+ CD25 high regulatory T cells (Treg) in patients with acute and chronic hepatitis B (AHB, CHB)...
  7. ncbi request reprint Trial of celecoxib in amyotrophic lateral sclerosis
    Merit E Cudkowicz
    Neurology Clinical Trials Unit, Massachusetts General Hospital, Harvard Medical School, Boston, 02172, USA
    Ann Neurol 60:22-31. 2006
    ..To determine whether chronic treatment with celecoxib, a cyclooxygenase-2 inhibitor that has been shown to be beneficial in preclinical testing, is safe and effective in amyotrophic lateral sclerosis (ALS)...
  8. ncbi request reprint PD-1 up-regulation is correlated with HIV-specific memory CD8+ T-cell exhaustion in typical progressors but not in long-term nonprogressors
    Ji Yuan Zhang
    Institute of Microbiology, Chinese Academy of Sciences, Beijing, China
    Blood 109:4671-8. 2007
    ..Blocking the PD-1/PD-L1 pathway may represent a new therapeutic option for this disease and provide more insight into immune pathogenesis in LTNPs...
  9. ncbi request reprint Increased regulatory T cells correlate with CD8 T-cell impairment and poor survival in hepatocellular carcinoma patients
    Junliang Fu
    Research Center for Biological Therapy, Beijing Institute of Infectious Diseases, Beijing 302 Hospital, Beijing, China
    Gastroenterology 132:2328-39. 2007
    ....
  10. ncbi request reprint Increased incidence of deep venous thrombosis in ALS
    M Muddasir Qureshi
    Neurology Clinical Trials Unit, Department of Neurology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Neurology 68:76-7. 2007
  11. ncbi request reprint Impact of atrial fibrillation on tricuspid and mitral annular dilatation and valvular regurgitation
    Xiaoyan Zhou
    First Department of Internal Medicine, Kagoshima University School of Medicine, Japan
    Circ J 66:913-6. 2002
    ..65, p < 0.001). Lone AF is associated with annular dilatation of both mitral and tricuspid valves, but the annular dilatation and valvular regurgitation are significantly greater in the tricuspid valve...
  12. ncbi request reprint [Surgery for BPH with impaired detrusor contractility: a report of 12 cases]
    Yong Sheng Song
    Department of Urology, Shengjing Hospital Affiliated to China Medical University, Shenyang, Liaoning 110004, China
    Zhonghua Nan Ke Xue 13:804-6. 2007
    ..To assess the outcome of prostatectomy simultaneously with suprapubic punctual cystostomy for BPH patients with impaired detrusor contractility...
  13. ncbi request reprint Stimulation of alpha2-adrenoceptors suppresses excitatory synaptic transmission in the medial prefrontal cortex of rat
    Xiao Hua Ji
    Institute of Neurobiology, Institutes of Brain Science, Fudan University, Shanghai, China
    Neuropsychopharmacology 33:2263-71. 2008
    ..The present study provides the first electrophysiological evidence that stimulation of alpha2A-AR inhibits excitatory synaptic transmission in the mPFC through a post-synaptic mechanism...
  14. ncbi request reprint High-dimensional spatial normalization of diffusion tensor images improves the detection of white matter differences: an example study using amyotrophic lateral sclerosis
    Hui Zhang
    Penn Image Computing and Science Laboratory, University of Pennsylvania, Philadelphia, PA 19104, USA
    IEEE Trans Med Imaging 26:1585-97. 2007
    ..We also found that high-dimensional approaches, by leveraging full tensor features instead of tensor-derived indices, can further improve the alignment of WM tracts...
  15. doi request reprint Prospective study of liver transplant recipients with HCV infection: evidence for a causal relationship between HCV and insulin resistance
    Aymin Delgado-Borrego
    Gastrointestinal Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA
    Liver Transpl 14:193-201. 2008
    ..Higher HCV RNA levels were associated with earlier elevations in HOMA-IR. Collectively, these results provide strong evidence that HCV induces the development of IR...
  16. doi request reprint Effects of allicin supplementation on plasma markers of exercise-induced muscle damage, IL-6 and antioxidant capacity
    Quan Sheng Su
    Chengdu Physical Education University, No 2 Ti Yuan Road, 610041 Chengdu, China
    Eur J Appl Physiol 103:275-83. 2008
    ..The results suggested that allicin might be a potential agent to reduce EIMD. Further studies concerning anti-inflammatory and anti-oxidative effects of allicin on EIMD are needed...
  17. doi request reprint TIP30 is associated with progression and metastasis of prostate cancer
    Hui Zhang
    Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Int J Cancer 123:810-6. 2008
    ..These data provide evidence that TIP30 plays a role in prostate cancer progression and that TIP30 overexpression may promote prostate cancer cell growth and metastasis...
  18. pmc HIV-1 Tat protein alter the tight junction integrity and function of retinal pigment epithelium: an in vitro study
    Ling Bai
    Key Laboratory of Ophthalmology, Ministry of Education Zhongshan Ophthalmic Center, Sun Yat Sen University, Guangzhou 510060, PR China
    BMC Infect Dis 8:77. 2008
    ..This study is to determine the effects of HIV-1 Tat proteins on the barrier function and tight-junction protein expression of retinal pigment epithelial cell (RPE)...
  19. ncbi request reprint The prognostic significance of preoperative plasma levels of osteopontin in patients with hepatocellular carcinoma
    Hui Zhang
    Liver Cancer Institute and Zhongshan Hospital, Institutes of Biomedical Science, Fudan University, 180 Feng Lin Road, Shanghai, 200032, China
    J Cancer Res Clin Oncol 132:709-17. 2006
    ..This suggests that the preoperative plasma OPN level can be used as a predictive marker for HCC recurrence and may be helpful to assess the prognosis of patients with HCC after surgery...
  20. ncbi request reprint Circulating and liver resident CD4+CD25+ regulatory T cells actively influence the antiviral immune response and disease progression in patients with hepatitis B
    Dongping Xu
    Beijing Institute of Infectious Diseases, Beijing 302 Hospital, 100 Xi Si Huan Middle Road, Beijing 100039, China
    J Immunol 177:739-47. 2006
    ..Together, our findings suggest that CD4+CD25+ Treg play an active role not only in modulating effectors of immune response to HBV infection, but also in influencing the disease prognosis in patients with hepatitis B...
  21. ncbi request reprint Real-time decoding of dopamine concentration changes in the caudate-putamen during tonic and phasic firing
    B Jill Venton
    Department of Chemistry and Neuroscience Center, University of North Carolina, Chapel Hill, NC 27599 3290, USA
    J Neurochem 87:1284-95. 2003
    ..These simulations show that synchronous phasic firing can produce spatially and temporally heterogeneous concentration profiles whereas asynchronous tonic firing elicits uniform, steady-state dopamine concentrations...
  22. ncbi request reprint Glutamate spillover in the striatum depresses dopaminergic transmission by activating group I metabotropic glutamate receptors
    Hui Zhang
    Department of Neurology, Columbia University, New York, New York 10032, USA
    J Neurosci 23:10585-92. 2003
    ..Thus, under conditions in which glutamate escapes the confines of its synapse, it can elicit the presynaptic suppression of dopaminergic neurotransmission...
  23. ncbi request reprint A correlative study between prevalence of chondromalacia patellae and sports injury in 4068 students
    Hui Zhang
    Affiliated Hospital of Taishan Medical College, Taishan, Shandong Province 271000, China
    Chin J Traumatol 6:370-4. 2003
    ..To study the prevalence of chondromalacia patella among college students and the correlation with sports injury...
  24. ncbi request reprint [Analysis of nosocomial methicillin-resistant staphylococcus aureus pulmonary infection in patients with coal miners' pneumoconiosis]
    Wen shou Xu
    Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 22:71-2. 2004
  25. ncbi request reprint Regulation of the development of mesencephalic dopaminergic systems by the selective expression of glial cell line-derived neurotrophic factor in their targets
    Nikolai Kholodilov
    Department of Neurology, Psychiatry, Pharmacology, and Pathology, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    J Neurosci 24:3136-46. 2004
    ..GDNF in VTA targets, however, is sufficient to regulate the adult number of DA neurons...
  26. ncbi request reprint Risk factors for recurrence of postoperative trichiasis: implications for trachoma blindness prevention
    Hui Zhang
    Children s Hospital Oakland Research Institute, Oakland, CA, USA
    Arch Ophthalmol 122:511-6. 2004
    ..Trachoma is the leading worldwide cause of preventable blindness. Surgery can alleviate trachomatous trichiasis (TT), the blinding sequelae of trachoma, but recurrence rates are high...
  27. ncbi request reprint Methyl-CpG-binding domain 2: a protective role in bladder carcinoma
    Yong Zhu
    Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 100:1853-8. 2004
    ..In the current case-control study, the authors investigated the association between MBD2 expression and bladder carcinoma risk...
  28. ncbi request reprint Heterosynaptic dopamine neurotransmission selects sets of corticostriatal terminals
    Nigel S Bamford
    Department of Neurology, University of Washington, Children s Hospital and Regional Medical Center, Seattle, WA 98105 USA
    Neuron 42:653-63. 2004
    ..Thus, dopamine, by filtering less active inputs, appears to reinforce specific sets of corticostriatal synaptic connections...
  29. ncbi request reprint Androgen receptor polymorphisms and risk of biochemical failure among prostatectomy patients
    Sara S Strom
    Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Prostate 60:343-51. 2004
    ..Little is known about the role of inherited genotypes in prostate cancer (PC) progression. This prospective study evaluated the predictive value of androgen receptor (AR) polymorphisms (CAG and GGC repeats) among prostatectomy patients...
  30. ncbi request reprint Maximum voluntary isometric contraction (MVIC)
    Merit Cudkowicz
    Neurology Clinical Trials Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Amyotroph Lateral Scler Other Motor Neuron Disord 5:84-5. 2004
  31. ncbi request reprint [Inhibitory effect of 4-1BBL combined with Hsp70-tumor antigen peptides on pulmonary metastasis of melanoma in mice]
    Hui Qiu
    Department of Biochemistry and Molecular Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, PR China
    Ai Zheng 24:781-6. 2005
    ....
  32. ncbi request reprint The existence of a linear system consisting of sympathetic endings in rat skin
    Li Yuan Liu
    College of Life Science, Beijing Normal University, Beijing, 100875, China
    Anat Embryol (Berl) 210:91-100. 2005
    ..These results are discussed in terms of physiological functions associated with hair follicles, sensory signal pathways and Meridians in Chinese traditional medicine...
  33. ncbi request reprint Transcriptional and behavioral interaction between 22q11.2 orthologs modulates schizophrenia-related phenotypes in mice
    Marta Paterlini
    Department of Physiology and Cellular Biophysics, Columbia University College of Physicians and Surgeons, 701 West 168th Street, New York, New York 10032, USA
    Nat Neurosci 8:1586-94. 2005
    ..This interaction modulates a number of schizophrenia-related phenotypes, providing a framework for understanding the high disease risk associated with this locus, the expression of the phenotype, or both...
  34. ncbi request reprint Prevention of fatal arrhythmias in high-risk subjects by fish oil n-3 fatty acid intake
    Alexander Leaf
    Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Circulation 112:2762-8. 2005
    ..Therefore, we hypothesized that these n-3 fatty acids might prevent potentially fatal ventricular arrhythmias in high-risk patients...
  35. ncbi request reprint HSP70 vaccine in combination with gene therapy with plasmid DNA encoding sPD-1 overcomes immune resistance and suppresses the progression of pulmonary metastatic melanoma
    Hui Geng
    Department of Biochemistry and Molecular Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, The People s Republic of China
    Int J Cancer 118:2657-64. 2006
    ..These findings suggest that the treatment with HSP70 vaccine followed by blockade of tumor-B7-H1 with sPD-1 may provide a promising approach for tumor immunotherapy...
  36. ncbi request reprint Statistical modeling of shape and appearance using the continuous medial representation
    Paul A Yushkevich
    Department of Radiology, University of Pennsylvania, USA
    Med Image Comput Comput Assist Interv 8:725-32. 2005
    ..The approach is illustrated by the principal components analysis of the shape and appearance of the hippocampus in T1-weighted MRI from a schizophrenia study...
  37. doi request reprint Arimoclomol at dosages up to 300 mg/day is well tolerated and safe in amyotrophic lateral sclerosis
    Merit E Cudkowicz
    Neurology Clinical Trials Unit, Massachusetts General Hospital, 13th Street, Charlestown, MA 02129, USA
    Muscle Nerve 38:837-44. 2008
    ..Arimoclomol CSF levels increased with dose. Arimoclomol was shown to be safe, and it crosses the blood-brain barrier. Serum pharmacokinetic profiles support dosing of three times per day. An efficacy study in ALS is planned...