- Optimizing the specificity of nucleic acid hybridizationDavid Yu Zhang
Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, USA
Nat Chem 4:208-14. 2012..Experiments with RNA also showed effective single-base change discrimination...
- Dynamic DNA nanotechnology using strand-displacement reactionsDavid Yu Zhang
Wyss Institute for Biologically Inspired Engineering, Harvard University, 3 Blackfan Circle, Room 530, Boston, Massachussetts 02115, USA
Nat Chem 3:103-13. 2011..This mechanism allows for the kinetic control of reaction pathways. Here, we review DNA strand-displacement-based devices, and look at how this relatively simple mechanism can lead to a surprising diversity of dynamic behaviour...