Research Topics
| Steven M ZeitelsSummaryAffiliation: Harvard University Country: USA Publications
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Publications
Office-based 532-nm pulsed KTP laser treatment of glottal papillomatosis and dysplasiaSteven M Zeitels
Department of Surgery, Harvard Medical School, and the Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital Boston, MA 02114, USA
Ann Otol Rhinol Laryngol 115:679-85. 2006..These factors provide enhanced hemostasis and improved intralesional energy absorbance. Finally, unlike the PDL, the KTP laser is a solid-state laser and is not prone to mechanical failure...
Office-based laryngeal laser surgery with local anesthesiaSteven M Zeitels
Department of Surgery, Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Curr Opin Otolaryngol Head Neck Surg 15:141-7. 2007..This style of minimally invasive surgery is becoming increasingly popular in the United States and abroad...
Office-based laryngeal laser surgery with the 532-nm pulsed-potassium-titanyl-phosphate laserSteven M Zeitels
Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, MA 02114, USA
Curr Opin Otolaryngol Head Neck Surg 15:394-400. 2007..The 532-nm pulsed-potassium-titanyl-phosphate laser has become our laser of choice in treating vocal-fold lesions and diseases for a number of transparent and practical reasons...
Adduction arytenopexy for vocal fold paralysis: indications and techniqueSteven M Zeitels
Department of Surgery, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA
J Laryngol Otol 118:508-16. 2004....
Laser applications in laryngology: past, present, and futureSteven M Zeitels
Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, One Bowdoin Square, Boston, MA 02114, USA
Otolaryngol Clin North Am 39:159-72. 2006
Modulation of vocal fold scar fibroblasts by adipose-derived stem/stromal cellsYoshihiko Kumai
Department of Surgery, Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Laryngoscope 120:330-7. 2010..To explore whether adipose-derived stem/stromal cells (ASCs) have therapeutic potential for treating scarred superficial lamina propria through the effects of secreted hepatocyte growth factor (HGF) on scar fibroblasts...
Modification and testing of a pneumatic dispensing device for controlled delivery of injectable materialsJames T Heaton
Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts, USA
Laryngoscope 122:2023-8. 2012....
High-speed videoendoscopic analysis of relationships between cepstral-based acoustic measures and voice production mechanisms in patients undergoing phonomicrosurgeryDaryush D Mehta
Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Ann Otol Rhinol Laryngol 121:341-7. 2012....
Office-based treatment of glottal dysplasia and papillomatosis with the 585-nm pulsed dye laser and local anesthesiaSteven M Zeitels
Department of Otology and Laryngology, Harvard Medical School, Boston, Massachusetts, USA
Ann Otol Rhinol Laryngol 113:265-76. 2004..Furthermore, this relatively safe, effective technique allowed for treatment of many patients (in a clinic setting) in whom classic surgery-related morbidity would have often delayed intervention...
Microlaryngoscopic and office-based injection of bevacizumab (Avastin) to enhance 532-nm pulsed KTP laser treatment of glottal papillomatosisSteven M Zeitels
Department of Surgery, Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Ann Otol Rhinol Laryngol Suppl 201:1-13. 2009..Therefore, sublesional injections of the antiangiogenic agent bevacizumab (Avastin) were given to assess the effect on disease recurrence and phonatory function...
Three-dimensional hydrogel model using adipose-derived stem cells for vocal fold augmentationHyoungshin Park
Department of Surgery, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Tissue Eng Part A 16:535-43. 2010..In particular, cogels of HA or collagen with fibrin enhanced proliferation, differentiation, and elastin expression...
Polarization-sensitive optical coherence tomography imaging of benign and malignant laryngeal lesions: an in vivo studyJames A Burns
Department of Surgery, Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts, USA
Otolaryngol Head Neck Surg 145:91-9. 2011..STUDY DESIGN. Prospective clinical trial...
532 nm pulsed potassium-titanyl-phosphate laser treatment of laryngeal papillomatosis under general anesthesiaJames A Burns
Department of Surgery, Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Laryngoscope 117:1500-4. 2007..This investigation provides the first report of the pulsed-KTP laser during microlaryngoscopy under general anesthesia...
Novel device for tissue cooling during endoscopic laryngeal laser surgery: thermal damage study in an ex vivo calf modelHae Jin Koo
Department of Surgery, Harvard Medical School, and the Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Ann Otol Rhinol Laryngol 121:485-9. 2012....
Crosstalk between adipose-derived stem/stromal cells and vocal fold fibroblasts in vitroYoshihiko Kumai
Department of Surgery, Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Laryngoscope 119:799-805. 2009..To explore adipose-derived stem cell/fibroblast interactions as a potential remodeling pathway for vocal fold scar...
Voice production mechanisms following phonosurgical treatment of early glottic cancerDaryush D Mehta
Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, MA 02114, USA
Ann Otol Rhinol Laryngol 119:1-9. 2010..Stroboscopic assessment is inadequate for this purpose...
Effects of 532 nm pulsed-KTP laser parameters on vessel ablation in the avian chorioallantoic membrane: implications for vocal fold mucosaMatthew S Broadhurst
Department of Surgery, Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Laryngoscope 117:220-5. 2007....
Local injection of bevacizumab (Avastin) and angiolytic KTP laser treatment of recurrent respiratory papillomatosis of the vocal folds: a prospective studySteven M Zeitels
Department of Surgery, Harvard Medical School, and the Center for Laryngeal Surgery and Voice Rehabilitation the Massachusetts General Hospital Institute of Health Professions, Massachusetts General Hospital, Boston, MA 02114, USA
Ann Otol Rhinol Laryngol 120:627-34. 2011..Since bevacizumab is a new therapeutic modality for RRP, there were also primary safety objectives to determine whether there was a pegative impact on the voice and whether there were local or systemic complications...
Office-based and microlaryngeal applications of a fiber-based thulium laserSteven M Zeitels
Department of Surgery, Harvard Medical School, USA
Ann Otol Rhinol Laryngol 115:891-6. 2006..Hemostasis was judged to be superior to experiences with the CO2 laser. In this pilot study, performing en bloc laryngeal cancer resection procedures was facilitated by use of the thulium laser...
A new instrument for intraoperative assessment of individual vocal foldsJames T Heaton
Department of Surgery, Harvard Medical School, Massachusetts General Hospital Boston, Massachusetts 02114, USA
Laryngoscope 115:1223-9. 2005..We therefore developed and bench-tested a new device we refer to as the aerodynamic vocal fold driver (AVFD)...
Thermal damage during thulium laser dissection of laryngeal soft tissue is reduced with air cooling: ex vivo calf model studyJames A Burns
Department of Surgery, Harvard Medical School, Boston, Massachusetts, USA
Ann Otol Rhinol Laryngol 116:853-7. 2007..This study investigated temperature changes and thermal trauma during thulium laser dissection of laryngeal tissue, with and without air cooling, in an ex vivo model...
Comparison of a flexible laryngoscope with calibrated sizing function to intraoperative measurementsJames B Kobler
Department of Surgery, Harvard Medical School, Boston, MA, USA
Ann Otol Rhinol Laryngol 115:733-40. 2006..Objective sizing of laryngeal lesions is complicated by subjective judgments of lesion boundaries, which can be indistinct in many cases...
Electromyographic control of a hands-free electrolarynx using neck strap musclesHeather L Kubert
Massachusetts General Hospital Center for Laryngeal Surgery and Voice Rehabilitation, Boston, MA, USA
J Commun Disord 42:211-25. 2009....
Photoangiolytic laser treatment of early glottic cancer: a new management strategySteven M Zeitels
Department of Surgery, Harvard Medical School, Boston, Massachusetts, USA
Ann Otol Rhinol Laryngol Suppl 199:3-24. 2008....
Phonomicrosurgery in singers and performing artists: treatment outcomes, management theories, and future directionsSteven M Zeitels
Department of Otology and Laryngology, Harvard Medical School, Boston, Massachusetts, USA
Ann Otol Rhinol Laryngol Suppl 190:21-40. 2002....
Foresight in laryngology and laryngeal surgery: a 2020 visionSteven M Zeitels
Department of Surgery, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Ann Otol Rhinol Laryngol Suppl 198:2-16. 2007..We hope that aspiring laryngeal surgeons will find elements of this discussion valuable for devising a strategic roadmap for research initiatives in laryngology and laryngeal surgery...
Chick chorioallantoic membrane as a model for simulating human true vocal foldsMatthew S Broadhurst
Department of Surgery, Harvard Medical School, Boston, MA, USA
Ann Otol Rhinol Laryngol 116:917-21. 2007..To characterize this model, we compared measurements of vessel diameters to superficial vessels in human vocal folds...
Aortic homograft reconstruction of partial laryngectomy defects: a new techniqueSteven M Zeitels
Department of Surgery, Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation Boston, Massachusetts 02114, USA
Ann Otol Rhinol Laryngol 121:301-6. 2012..We sought to identify a new reconstructive technique that would provide an alternative to total laryngectomy in as many patients as possible...
Predicting clinical efficacy of photoangiolytic and cutting/ablating lasers using the chick chorioallantoic membrane model: implications for endoscopic voice surgeryJames A Burns
Department of Surgery, Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Laryngoscope 118:1109-24. 2008..Such information is essential for optimizing the effectiveness of lasers in treating laryngeal pathology while preserving vocal function...
Imaging the human vocal folds in vivo with optical coherence tomography: a preliminary experienceAdam M Klein
Department of Surgery, Harvard Medical School, Boston, Massachusetts, USA
Ann Otol Rhinol Laryngol 115:277-84. 2006..To our knowledge, this study is the first application of PS-OCT for in vivo imaging of the human vocal folds...
Safety and dosing of bevacizumab (avastin) for the treatment of recurrent respiratory papillomatosisSimon R Best
Department of Surgery, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA
Ann Otol Rhinol Laryngol 121:587-93. 2012..The primary objective of this study was to report on the safety of increased doses of bevacizumab for the treatment of RRP...
Pulsed angiolytic laser treatment of ectasias and varices in singersSteven M Zeitels
Department of Surgery, Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, MA 02114, USA
Ann Otol Rhinol Laryngol 115:571-80. 2006..Vessel wall rupture was commonplace during use of the 585-nm PDL, but rarely occurred during photoangiolysis with the 532-nm pulsed KTP laser...
Carbon dioxide laser fiber for laryngeal cancer surgerySteven M Zeitels
Department of Surgery, Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, One Bowdoin Square, 11th Floor, Boston, MA 02114, USA
Ann Otol Rhinol Laryngol 115:535-41. 2006..It will likely enhance the ability of any surgeon to extend his or her indications for performing endoscopic laryngeal cancer resections regardless of philosophy (en bloc resection or piecemeal)...
Medialization laryngoplasty with Gore-Tex for voice restoration secondary to glottal incompetence: indications and observationsSteven M Zeitels
Department of Otology and Laryngology, Harvard Medical School, and Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
Ann Otol Rhinol Laryngol 112:180-4. 2003..There was superior ease in handling, placement, and in vivo adjustability...
Cooling the "oven": a temperature study of air and glottal tissue during laser surgery in an ex vivo calf larynx modelJames A Burns
Department of Surgery, Harvard Medical School, Boston, MA, USA
Ann Otol Rhinol Laryngol 119:684-9. 2010..We report the effects of cooling on air and tissue temperatures that occurred during simulated laryngeal laser surgery with KTP and thulium lasers in an ex vivo calf model...
585-nm pulsed dye laser treatment of glottal dysplasiaRamon A Franco
Department of Otology and Laryngology, Harvard Medical School, Boston, Massachusetts, USA
Ann Otol Rhinol Laryngol 112:751-8. 2003..In this initial trial, the PDL provided relatively safe and effective treatment for glottal dysplasia. Analysis of patterns of recurrence will require longer follow-up...
Real-time tracking of vocal fold injections with optical coherence tomographyJames A Burns
Department of Surgery, Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Laryngoscope 119:2182-6. 2009..Using OCT both to delineate the depth of subepithelial injections real-time and to serially image the implant over time would be valuable, and has not been demonstrated previously...
Hypopharyngeal extrusion of 2.5 feet (76 cm) of polytetrafluoroethylene (Gore-Tex): initial laser-assisted office-based removal and micropharyngeal completionSteven Feinberg
Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, One Bowdoin Square, 11th Floor, Boston, MA 02114, USA
Ann Otol Rhinol Laryngol 119:573-7. 2010....
Function preservation surgery in patients with chondrosarcoma of the cricoid cartilageSteven M Zeitels
Department of Surgery, Harvard Medical School, Boston, Massachusetts, USA
Ann Otol Rhinol Laryngol 120:603-7. 2011..Surgeons should carefully modify the core principles of epithelial cancer surgery techniques, adjusting to the different biological behavior of laryngeal chondrosarcomas...
Quantitative and comparative studies of the vocal fold extracellular matrix II: collagenMariah S Hahn
Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Boston, Massachusetts 02114, USA
Ann Otol Rhinol Laryngol 115:225-32. 2006..Collagen types I and III seem to be the dominant LP collagens. Spatial variations in collagen turnover appear to exist that may contribute to normal LP physiology...
Initial anatomic geographic presentation of glottal dysplasiaYonatan Lahav
Department of Surgery, Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Ann Otol Rhinol Laryngol 118:321-5. 2009....
Posterior glottic diastasis: mechanically deceptive and often overlookedSteven M Zeitels
Department of Surgery, Harvard Medical School, Boston, Massachusetts, USA
Ann Otol Rhinol Laryngol 120:71-80. 2011..The initial experience with surgical reconstruction is preliminary, but encouraging...
Perspectives on adipose-derived stem/stromal cells as potential treatment for scarred vocal folds: opportunity and challengesYoshihiko Kumai
Department of Surgery Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation Massachusetts General Hospital, Boston, MA 02114, USA
Curr Stem Cell Res Ther 5:175-81. 2010..The roles of stem cell-derived cytokines in paracrine signaling need to be further explored at a cellular level in vitro, and then extended to in vivo experiments...
Comparison of effects of 2 harvesting methods on fat autograftHyoungshin Park
Center for Laryngeal Surgery and Voice Rehabilitation, Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Laryngoscope 118:1493-9. 2008..Considering this, we compared viability of fat tissues obtained by these two techniques. We also examined whether basic fibroblast growth factor (bFGF) would increase cell proliferation in samples harvested by these methods...
Technique of en block laser endoscopic frontolateral laryngectomy for glottic cancerSteven M Zeitels
Department of Otology and Laryngology, Harvard Medical School, Boston, MA, USA
Laryngoscope 114:175-80. 2004..The nuances of en block endoscopic frontolateral laryngectomy are presented with the hope that more surgeons will adopt this philosophy as an aspect of their armamentarium...
Endoscopic measurement of vocal fold movement during adduction and abductionSeth H Dailey
Department of Otology and Laryngology, Harvard Medical School, Division of Otolaryngology, Brigham and Women's Hospital, Boston, MA 02115, USA
Laryngoscope 115:178-83. 2005..Accuracy is significantly enhanced by correction of distortion in the images. This approach holds promise for objective characterization of vocal fold function in patients with a variety of disorders...
Subepithelial vocal fold infusion: a useful diagnostic and therapeutic techniqueJames A Burns
Department of Surgery, Harvard Medical School, Boston, Massachusetts 02114, USA
Ann Otol Rhinol Laryngol 121:224-30. 2012..The purpose of this investigation was to examine the indications, methods, and benefits of subepithelial infusion of saline solution as an adjunct technique during phonomicrosurgery...
Voice and treatment outcome from phonosurgical management of early glottic cancerSteven M Zeitels
Department of Otology and Laryngology, Harvard Medical School, Boston, Massachusetts, USA
Ann Otol Rhinol Laryngol Suppl 190:3-20. 2002..These favorable results are based on establishing aerodynamic glottal competency and preserving the layered microstructure of noncancerous glottal tissue...
Suspension laryngoscopy revisitedSteven M Zeitels
Department of Otology and Laryngology, Harvard Medical School, and Division of Laryngology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
Ann Otol Rhinol Laryngol 113:16-22. 2004..A prospective assessment of 120 cases revealed effective use of suspension laryngoscopy in all. We believe that only a minority of surgeons has actually seen true suspension laryngoscopy and that its merits are worthy of reexamination...
Early versus late injection medialization for unilateral vocal cord paralysisAaron D Friedman
Department of Surgery, Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Laryngoscope 120:2042-6. 2010..late (>6 months) injection medialization laryngoplasty impacts the need for subsequent open-neck reconstruction to restore vocal function in patients with unilateral vocal cord paralysis...
Ambulatory monitoring of disordered voicesRobert E Hillman
Department of Surgery, Harvard Medical School, MGH Center for Laryngeal Surgery and Voice Rehabilitation, One Bowdoin Square, Ilth Floor, Boston, MA 02114, USA
Ann Otol Rhinol Laryngol 115:795-801. 2006..CONCLUSIONS: The results generally support the recent application of accelerometers as phonation sensors in ambulatory voice monitoring systems that can be used in the clinical assessment and management of voice disorders...
Microstereo-laryngoscopic lipoinjection: practical considerationsJames A Burns
Department of Otology and Laryngology, Harvard Medical School, Division of Laryngology, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114, U.S.A
Laryngoscope 114:1864-7. 2004
Laryngology and phonosurgerySteven M Zeitels
Department of Otology and Laryngology, Harvard Medical School, Boston, USA
N Engl J Med 349:882-92. 2003
Optimizing voice after endoscopic partial laryngectomySteven M Zeitels
Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles Street, Boston, MA 02114, USA
Otolaryngol Clin North Am 37:627-36. 2004..These favorable results are based on the fact that after effective glottal closure is achieved through the reconstruction, the primary oscillator is the layered microstructure of noncancerous glottal tissue...
The evaluation of benign glottic lesions: rigid telescopic stroboscopy versus suspension microlaryngoscopySeth H Dailey
Department of Surgery, University of Wisconsin School of Medicine, Division of Otolaryngology Head and Neck Surgery, University of Wisconsin Hospital and Clinics, Madison, Wisconsin 53792, USA
J Voice 21:112-8. 2007..4) Microlaryngoscopy is the final diagnostic step in the evaluation of glottic pathology. Meticulous inspection and palpation of the glottis are recommended during SML...
Surface electromyographic activity in total laryngectomy patients following laryngeal nerve transfer to neck strap musclesJames T Heaton
W. M. Keck Foundation Neural Prosthesis Research Center, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA
Ann Otol Rhinol Laryngol 113:754-64. 2004..The results show that neck surface electromyography is an effective control source for hands-free electrolarynx activation, and that RLN transfer may provide the best approach for obtaining phonation-related activity...
Endoscopic laser resection of laryngeal cancer: is it oncologically safe? Position statement from the American Broncho-Esophagological AssociationJames A Burns
Department of Surgery, Harvard Medical School, Boston, Massachusetts, USA
Ann Otol Rhinol Laryngol 118:399-404. 2009..Specific contraindications for supraglottic cancer include bilateral arytenoid involvement and direct extension into the neck...
Pulsed potassium-titanyl-phosphate laser photoangiolytic treatment of mucosal squamous cell carcinoma in the hamster cheek pouchJames A Burns
Department of Surgery, Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Laryngoscope 121:942-6. 2011..This study tests the efficacy of photoangiolysis with the KTP laser in treating squamous cell carcinoma in an established animal model...
Imaging the mucosa of the human vocal fold with optical coherence tomographyJames A Burns
Department of Surgery, Harvard Medical School, Boston, MA 02114, USA
Ann Otol Rhinol Laryngol 114:671-6. 2005..We believe that these imaging techniques will have applications in the exploration of solutions to vocal fold scarring and in imaging vocal fold disorders in the clinic and operating room...
Quantitative and comparative studies of the vocal fold extracellular matrix. I: Elastic fibers and hyaluronic acidMariah S Hahn
Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Boston, USA
Ann Otol Rhinol Laryngol 115:156-64. 2006..Fibrillin-1 staining suggests that stress in the human LP may be particularly high in the superior superficial layer, and tropoelastin staining indicates that the rate of LP elastin turnover may vary spatially...
Assessment of canine vocal fold function after injection of a new biomaterial designed to treat phonatory mucosal scarringSandeep S Karajanagi
Department of Surgery, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, MA 02114, USA
Ann Otol Rhinol Laryngol 120:175-84. 2011..By using a US Food and Drug Administration-approved polymer, polyethylene glycol (PEG), we created a novel hydrogel (PEG30) and investigated its effects on multiple vocal fold structural and functional parameters...
Pediatric video laryngo-stroboscopyChristopher J Hartnick
Department of Otology and Laryngology, Division of Pediatric Otolaryngology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114 3914, USA
Int J Pediatr Otorhinolaryngol 69:215-9. 2005..However, flexible laryngoscopy is readily performed in newborns and young children. This paper describes the use of a new trans-nasal, digital flexible laryngoscope, which allows for laryngo-stroboscopy in children...
Dynamic imaging of vocal fold oscillation with four-dimensional optical coherence tomographyJames B Kobler
Department of Surgery, Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Laryngoscope 120:1354-62. 2010..If feasible, this approach could be a useful research tool and spur development of new clinical instrumentation...
Measurement of vocal fold collision forces during phonation: methods and preliminary dataHeather E Gunter
Harvard University and Harvard MIT Division of Health Sciences and Technology, Cambridge, MA 02139, USA
J Speech Lang Hear Res 48:567-76. 2005..Sensor modifications are proposed so that it can be used to reliably estimate collision force in individuals with 2 vibrating vocal folds and with changing vocal tract conformations...
Office-based pulsed dye laser treatment for hemorrhagic telangiectasias and epistaxisChristopher J Hartnick
Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston 02114, USA
Laryngoscope 113:1085-7. 2003
Recurrent laryngeal nerve injuries after esophagectomyCameron D Wright
Harvard Medical School, Boston, MA, USA
Thorac Surg Clin 16:23-33, v. 2006..Early treatment may include supportive care with a speech pathologist or injection of the vocal-cord with temporary material to improve glottic closure. Definitive treatment can best be performed by medialization thyroplasty...
Malignant transformation of a highly aggressive human papillomavirus type 11-associated recurrent respiratory papillomatosisHarrison W Lin
Department of Otolaryngology Head and Neck Surgery, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
Am J Otolaryngol 31:291-6. 2010..The objective is to present an uncommon case of squamous cell carcinoma (SCC) arising from extensive recurrent respiratory papillomatosis (RRP) involving the upper and lower airway and temporal bone...
Management of common voice problems: Committee reportSteven M Zeitels
Department of Otology and Laryngology, Harvard Medical School, and the Division of Laryngology, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
Otolaryngol Head Neck Surg 126:333-48. 2002..This report provides the reader with a state-of-the-art update on a number of common voice problems that require phonosurgical intervention...
Chevalier Jackson lecture 2006. Concepts and culture of innovationSteven M Zeitels
Department of Surgery, Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Ann Otol Rhinol Laryngol 116:479-82. 2007
A laryngeal dissection station: educational paradigms in phonosurgerySeth H Dailey
Department of Otology and Laryngology, Harvard Medical School, Division of Otolaryngology, Brigham and Women s Hospital, Boston, MA 02115, USA
Laryngoscope 114:878-82. 2004..Finally, many teaching programs do not have a high volume of these procedures, and there is a significant need to transmit this information in continuing education courses...
Indirect low-intensity ultrasonic stimulation for tissue engineeringHyoungshin Park
Center for Laryngeal Surgery and Voice Rehabilitation, Department of Surgery, Massachusetts General Hospital, Boston, MA 02114, USA
J Tissue Eng 2010:973530. 2010..Our data suggests that LIUS could be a useful modality for improving graft survival in vivo...
585-nm pulsed dye laser treatment of glottal papillomatosisRamon A Franco
Department of Otology and Laryngology, Harvard Medical School, Boston, Massachusetts, USA
Ann Otol Rhinol Laryngol 111:486-92. 2002..Since the lesions involute without complete resection of the diseased epithelium, the anterior commissure can be treated to minimize the number of procedures. To study patterns of recurrence will require longer follow-up...
Staged closure of tracheogastrocutaneous fistula after esophagectomy for infiltrative granular cell tumorRobert Merritt
Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Mass 02114, USA
J Thorac Cardiovasc Surg 134:805-7. 2007
Re: prospective trial of voice outcomes after thyroidectomy: evaluation of patient-reported and clinician-determined voice assessments in identifying post-thyroidectomy dysphoniaSteven M Zeitels
Surgery 143:822-3. 2008
Evolution of laryngeal cancer surgeryAlfio Ferlito
Department of Otolaryngology--Head and Neck Surgery, University of Udine, Italy
Acta Otolaryngol 122:665-72. 2002
Microflap laryngosplasty for treating an anterior-commissure web with papillomatosisLee M Akst
Department of Otolaryngology, Loyola University Stritch School of Medicine, Maywood, Illinois, USA
Laryngoscope 117:1496-9. 2007
Measurements of vocal fold elasticity using the linear skin rheometerMarkus M Hess
Department of Phoniatrics and Pediatric Audiology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
Folia Phoniatr Logop 58:207-16. 2006..A series of studies was performed on animal and human excised larynges to determine if the LSR technique can be applied to the vocal fold...
Effects of growth factors on extracellular matrix production by vocal fold fibroblasts in 3-dimensional cultureYing Luo
Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
Tissue Eng 12:3365-74. 2006..The results also suggest that multiple growth factors might be employed sequentially or in combination to program the makeup of cell-hydrogel constructs for vocal fold tissue repair...
Collagen composite hydrogels for vocal fold lamina propria restorationMariah S Hahn
Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA
Biomaterials 27:1104-9. 2006..Collagen-alginate hydrogels appear to be promising materials for VF restoration, warranting further investigation...
Laryngeal dysplasia and other epithelial changes on endoscopic biopsy: what does it all mean to the individual patient?Kenneth O Devaney
ORL J Otorhinolaryngol Relat Spec 66:1-4. 2004
Experience with office-based pulsed-dye laser (PDL) treatmentSteven M Zeitels
Ann Otol Rhinol Laryngol 116:317-8. 2007
Hyaluronic acid-based microgels and microgel networks for vocal fold regenerationXinqiao Jia
Department of Materials Science and Engineering, 201 DuPont Hall, University of Delaware, Newark, Delaware 19716, USA
Biomacromolecules 7:3336-44. 2006....
Midmembranous vocal fold lamina propria proteoglycans across selected speciesMariah S Hahn
Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
Ann Otol Rhinol Laryngol 114:451-62. 2005..Finally, the noted canine, porcine, and ferret LP subdivisions may yield insight into the adaptation of LP microstructure to the phonatory needs of each species...
Imaging of the calf vocal fold with high-frequency ultrasoundConor J Walsh
Department of Mechanical Engineering, Harvard MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, USA
Laryngoscope 118:1894-9. 2008..The objective of this study was to assess the ability of high-frequency ultrasound to image vocal fold anatomy and injected biomaterials...
