Hai Tao Yuan

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi Activation of the orphan endothelial receptor Tie1 modifies Tie2-mediated intracellular signaling and cell survival
    Hai Tao Yuan
    Division of Molecular and Vascular Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, RW663, Boston, MA 02215, USA
    FASEB J 21:3171-83. 2007
  2. ncbi Angiopoietin 2 is a partial agonist/antagonist of Tie2 signaling in the endothelium
    Hai Tao Yuan
    Molecular and Vascular Medicine, Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Mol Cell Biol 29:2011-22. 2009
  3. ncbi Excess circulating angiopoietin-2 may contribute to pulmonary vascular leak in sepsis in humans
    Samir M Parikh
    Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS Med 3:e46. 2006
  4. ncbi Receptor tyrosine kinase Tie-1 overexpression in endothelial cells upregulates adhesion molecules
    Barden Chan
    Division of Interdisciplinary Medicine and Biotechnology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, RW 563, Boston, MA 02215, USA
    Biochem Biophys Res Commun 371:475-9. 2008
  5. ncbi Soluble endoglin contributes to the pathogenesis of preeclampsia
    Shivalingappa Venkatesha
    Center for Vascular Biology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue, Boston, Massachusetts 02215, USA
    Nat Med 12:642-9. 2006
  6. ncbi Soluble erythropoietin receptor contributes to erythropoietin resistance in end-stage renal disease
    Eliyahu V Khankin
    Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 5:e9246. 2010
  7. ncbi Dysmorphogenesis of kidney cortical peritubular capillaries in angiopoietin-2-deficient mice
    Jolanta E Pitera
    Institute of Child Health, University College London, London, UK
    Am J Pathol 165:1895-906. 2004
  8. ncbi Angiopoietin correlates with glomerular capillary loss in anti-glomerular basement membrane glomerulonephritis
    Hai Tao Yuan
    Nephro Urology Unit, Institute of Child Health, University College London, London, England, United Kingdom
    Kidney Int 61:2078-89. 2002

Collaborators

Detail Information

Publications8

  1. ncbi Activation of the orphan endothelial receptor Tie1 modifies Tie2-mediated intracellular signaling and cell survival
    Hai Tao Yuan
    Division of Molecular and Vascular Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, RW663, Boston, MA 02215, USA
    FASEB J 21:3171-83. 2007
    ..The experiments also constitute a paradigm for how endothelial integrity is fine-tuned by the interplay between closely related receptors by a single growth factor...
  2. ncbi Angiopoietin 2 is a partial agonist/antagonist of Tie2 signaling in the endothelium
    Hai Tao Yuan
    Molecular and Vascular Medicine, Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Mol Cell Biol 29:2011-22. 2009
    ....
  3. ncbi Excess circulating angiopoietin-2 may contribute to pulmonary vascular leak in sepsis in humans
    Samir M Parikh
    Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS Med 3:e46. 2006
    ..We hypothesized that Ang-2 contributes to endothelial barrier disruption in sepsis-associated lung injury, a condition involving the mature vasculature...
  4. ncbi Receptor tyrosine kinase Tie-1 overexpression in endothelial cells upregulates adhesion molecules
    Barden Chan
    Division of Interdisciplinary Medicine and Biotechnology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, RW 563, Boston, MA 02215, USA
    Biochem Biophys Res Commun 371:475-9. 2008
    ..Collectively, our data show that Tie-1 has a proinflammatory property and may play a role in the endothelial inflammatory diseases such as atherosclerosis...
  5. ncbi Soluble endoglin contributes to the pathogenesis of preeclampsia
    Shivalingappa Venkatesha
    Center for Vascular Biology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue, Boston, Massachusetts 02215, USA
    Nat Med 12:642-9. 2006
    ..Our results suggest that sEng may act in concert with sFlt1 to induce severe preeclampsia...
  6. ncbi Soluble erythropoietin receptor contributes to erythropoietin resistance in end-stage renal disease
    Eliyahu V Khankin
    Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 5:e9246. 2010
    ..Erythropoietin acts through the erythropoietin receptor (EpoR) present in erythroblasts. Alternative mRNA splicing produces a soluble form of EpoR (sEpoR) found in human blood, however its role in anemia is not known...
  7. ncbi Dysmorphogenesis of kidney cortical peritubular capillaries in angiopoietin-2-deficient mice
    Jolanta E Pitera
    Institute of Child Health, University College London, London, UK
    Am J Pathol 165:1895-906. 2004
    ....
  8. ncbi Angiopoietin correlates with glomerular capillary loss in anti-glomerular basement membrane glomerulonephritis
    Hai Tao Yuan
    Nephro Urology Unit, Institute of Child Health, University College London, London, England, United Kingdom
    Kidney Int 61:2078-89. 2002
    ..We hypothesized that the growth factors modulating embryonic kidney endothelial cell survival and capillary morphogenesis may be implicated in capillary loss that occurs in immune-mediated glomerulonephritis (GN)...