Toshimi Yoshida

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc A complex network of regulatory elements in Ikaros and their activity during hemo-lymphopoiesis
    Christoph Kaufmann
    Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    EMBO J 22:2211-23. 2003
  2. doi request reprint Ikaros fingers on lymphocyte differentiation
    Toshimi Yoshida
    Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Bldg 149 3, 13th St, Charlestown, MA, 02129, USA
    Int J Hematol 100:220-9. 2014
  3. pmc The role of the chromatin remodeler Mi-2beta in hematopoietic stem cell self-renewal and multilineage differentiation
    Toshimi Yoshida
    Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Genes Dev 22:1174-89. 2008
  4. pmc Transcriptional regulation of the Ikzf1 locus
    Toshimi Yoshida
    Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA
    Blood 122:3149-59. 2013
  5. pmc Genome-wide lineage-specific transcriptional networks underscore Ikaros-dependent lymphoid priming in hematopoietic stem cells
    Samuel Yao Ming Ng
    Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Immunity 30:493-507. 2009
  6. pmc Early hematopoietic lineage restrictions directed by Ikaros
    Toshimi Yoshida
    Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Nat Immunol 7:382-91. 2006
  7. doi request reprint Loss of Ikaros DNA-binding function confers integrin-dependent survival on pre-B cells and progression to acute lymphoblastic leukemia
    Ila Joshi
    Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA
    Nat Immunol 15:294-304. 2014
  8. ncbi request reprint Ikaros and chromatin regulation in early hematopoiesis
    Samuel Yao Ming Ng
    Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Curr Opin Immunol 19:116-22. 2007
  9. pmc Awakening lineage potential by Ikaros-mediated transcriptional priming
    Toshimi Yoshida
    Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Curr Opin Immunol 22:154-60. 2010
  10. pmc Promoter decommissioning by the NuRD chromatin remodeling complex triggers synaptic connectivity in the mammalian brain
    Tomoko Yamada
    Department of Anatomy and Neurobiology, Washington University in St Louis School of Medicine, St Louis, MO 63110, USA Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA
    Neuron 83:122-34. 2014

Collaborators

Detail Information

Publications10

  1. pmc A complex network of regulatory elements in Ikaros and their activity during hemo-lymphopoiesis
    Christoph Kaufmann
    Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    EMBO J 22:2211-23. 2003
    ....
  2. doi request reprint Ikaros fingers on lymphocyte differentiation
    Toshimi Yoshida
    Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Bldg 149 3, 13th St, Charlestown, MA, 02129, USA
    Int J Hematol 100:220-9. 2014
    ....
  3. pmc The role of the chromatin remodeler Mi-2beta in hematopoietic stem cell self-renewal and multilineage differentiation
    Toshimi Yoshida
    Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Genes Dev 22:1174-89. 2008
    ..Thus, Mi-2beta provides the hematopoietic system with immune cell capabilities as well as with an extensive regenerative capacity...
  4. pmc Transcriptional regulation of the Ikzf1 locus
    Toshimi Yoshida
    Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA
    Blood 122:3149-59. 2013
    ..Mutations in the Ikzf1 regulatory elements and their interacting factors are likely to have adverse effects on lymphopoiesis and contribute to leukemogenesis. ..
  5. pmc Genome-wide lineage-specific transcriptional networks underscore Ikaros-dependent lymphoid priming in hematopoietic stem cells
    Samuel Yao Ming Ng
    Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Immunity 30:493-507. 2009
    ..Taken together, our studies provide new insight into the priming and restriction of lineage potentials during early hematopoiesis and identify Ikaros as a key bivalent regulator of this process...
  6. pmc Early hematopoietic lineage restrictions directed by Ikaros
    Toshimi Yoshida
    Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Nat Immunol 7:382-91. 2006
    ..Using this approach, we identify previously unknown pivotal functions for Ikaros in distinct fate 'decisions' in the early hematopoietic hierarchy...
  7. doi request reprint Loss of Ikaros DNA-binding function confers integrin-dependent survival on pre-B cells and progression to acute lymphoblastic leukemia
    Ila Joshi
    Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA
    Nat Immunol 15:294-304. 2014
    ....
  8. ncbi request reprint Ikaros and chromatin regulation in early hematopoiesis
    Samuel Yao Ming Ng
    Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Curr Opin Immunol 19:116-22. 2007
    ..Genetic studies of this family of nuclear factors are now providing unique insight into the functional molecular signatures that bestow plasticity to the hematopoietic stem cell and its early progeny...
  9. pmc Awakening lineage potential by Ikaros-mediated transcriptional priming
    Toshimi Yoshida
    Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Curr Opin Immunol 22:154-60. 2010
    ..Loss of Ikaros removes the lymphoid leg of the immune system and may confer aberrant self-renewing properties to myeloid progenitors...
  10. pmc Promoter decommissioning by the NuRD chromatin remodeling complex triggers synaptic connectivity in the mammalian brain
    Tomoko Yamada
    Department of Anatomy and Neurobiology, Washington University in St Louis School of Medicine, St Louis, MO 63110, USA Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA
    Neuron 83:122-34. 2014
    ..Our findings define NuRD-dependent promoter decommissioning as a developmentally regulated programming mechanism that drives synaptic connectivity in the mammalian brain. ..