Toshimi Yoshida

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi A complex network of regulatory elements in Ikaros and their activity during hemo-lymphopoiesis
    Christoph Kaufmann
    Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    EMBO J 22:2211-23. 2003
  2. ncbi The role of the chromatin remodeler Mi-2beta in hematopoietic stem cell self-renewal and multilineage differentiation
    Toshimi Yoshida
    Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Genes Dev 22:1174-89. 2008
  3. ncbi Genome-wide lineage-specific transcriptional networks underscore Ikaros-dependent lymphoid priming in hematopoietic stem cells
    Samuel Yao Ming Ng
    Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Immunity 30:493-507. 2009
  4. ncbi Ikaros and chromatin regulation in early hematopoiesis
    Samuel Yao Ming Ng
    Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Curr Opin Immunol 19:116-22. 2007
  5. ncbi Awakening lineage potential by Ikaros-mediated transcriptional priming
    Toshimi Yoshida
    Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Curr Opin Immunol 22:154-60. 2010
  6. ncbi Early hematopoietic lineage restrictions directed by Ikaros
    Toshimi Yoshida
    Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Nat Immunol 7:382-91. 2006

Collaborators

Detail Information

Publications6

  1. ncbi A complex network of regulatory elements in Ikaros and their activity during hemo-lymphopoiesis
    Christoph Kaufmann
    Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    EMBO J 22:2211-23. 2003
    ....
  2. ncbi The role of the chromatin remodeler Mi-2beta in hematopoietic stem cell self-renewal and multilineage differentiation
    Toshimi Yoshida
    Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Genes Dev 22:1174-89. 2008
    ..Thus, Mi-2beta provides the hematopoietic system with immune cell capabilities as well as with an extensive regenerative capacity...
  3. ncbi Genome-wide lineage-specific transcriptional networks underscore Ikaros-dependent lymphoid priming in hematopoietic stem cells
    Samuel Yao Ming Ng
    Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Immunity 30:493-507. 2009
    ..Taken together, our studies provide new insight into the priming and restriction of lineage potentials during early hematopoiesis and identify Ikaros as a key bivalent regulator of this process...
  4. ncbi Ikaros and chromatin regulation in early hematopoiesis
    Samuel Yao Ming Ng
    Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Curr Opin Immunol 19:116-22. 2007
    ..Genetic studies of this family of nuclear factors are now providing unique insight into the functional molecular signatures that bestow plasticity to the hematopoietic stem cell and its early progeny...
  5. ncbi Awakening lineage potential by Ikaros-mediated transcriptional priming
    Toshimi Yoshida
    Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Curr Opin Immunol 22:154-60. 2010
    ..Loss of Ikaros removes the lymphoid leg of the immune system and may confer aberrant self-renewing properties to myeloid progenitors...
  6. ncbi Early hematopoietic lineage restrictions directed by Ikaros
    Toshimi Yoshida
    Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Nat Immunol 7:382-91. 2006
    ..Using this approach, we identify previously unknown pivotal functions for Ikaros in distinct fate 'decisions' in the early hematopoietic hierarchy...