Genomes and Genes
Calvin K Yip
Affiliation: Harvard University
- Molecular architecture of the TRAPPII complex and implications for vesicle tetheringCalvin K Yip
Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA
Nat Struct Mol Biol 17:1298-304. 2010..TRAPPII binds the Ypt1 GTPase and probably uses the TRAPPI catalytic core to promote guanine nucleotide exchange. We discuss the implications of the structure of TRAPPII for coat interaction and TRAPPII-associated human pathologies...
- The monopolin complex crosslinks kinetochore components to regulate chromosome-microtubule attachmentsKevin D Corbett
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 250 Longwood Avenue, Boston, MA 02115, USA
Cell 142:556-67. 2010..cerevisiae meiosis I and to suppress merotelic attachment in S. pombe mitosis, and crosslinking rDNA repeats to aid rDNA silencing...
- Molecular structure and flexibility of the yeast coatomer as revealed by electron microscopyCalvin K Yip
Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA
J Mol Biol 408:825-31. 2011..Our analyses provide the first three-dimensional picture of the complete coatomer and reveal substantial conformational flexibility likely to be critical for its scaffolding function...
- Structure of the human mTOR complex I and its implications for rapamycin inhibitionCalvin K Yip
Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA
Mol Cell 38:768-74. 2010....