Affiliation: Harvard University
- Optical properties of selected native and coagulated human brain tissues in vitro in the visible and near infrared spectral rangeA N Yaroslavsky
Wellman Laboratories of Photomedicine, Department of Dermatology, Boston, MA 02114, USA
Phys Med Biol 47:2059-73. 2002..A comparison with data from the literature revealed the importance of the employed tissue preparation technique and the impact of the theoretical model used to extract the optical coefficients from the measured quantities...
- Fluorescence polarization of tetracycline derivatives as a technique for mapping nonmelanoma skin cancersAnna N Yaroslavsky
Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, Massachusetts 02114, USA
J Biomed Opt 12:014005. 2007..Therefore, the developed technique can provide an important new tool for image-guided cancer surgery...
- Combining multispectral polarized light imaging and confocal microscopy for localization of nonmelanoma skin cancerAnna N Yaroslavsky
Harvard Medical School, Massachusetts General Hospital, Wellman Laboratories of Photomedicine, Department of Dermatology, Boston, Massachusetts 02114, USA
J Biomed Opt 10:14011. 2005..A combination of MSPLI and CM appears to be complementary. This combined in situ technique has potential to guide cancer surgery more rapidly and at lower cost than conventional histopathology...
- Fluorescence polarization imaging for delineating nonmelanoma skin cancersA N Yaroslavsky
Wellman Laboratories of Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
Opt Lett 29:2010-2. 2004..The results suggest that this optical technique may be suitable for real-time noninvasive demarcation of epithelial cancers...
- Demarcation of nonmelanoma skin cancer margins in thick excisions using multispectral polarized light imagingAnna N Yaroslavsky
Wellman Laboratories of Photomedicine, Department of Dermatology, Boston, Massachusetts 02114, USA
J Invest Dermatol 121:259-66. 2003..The study demonstrates that the suggested technique has significant potential as a guidance tool in tumor excision surgery...
- Optical properties of normal and cancerous human skin in the visible and near-infrared spectral rangeElena Salomatina
Massachusetts General Hospital, Wellman Center for Photomedicine, Boston, Massachusetts 02114, USA
J Biomed Opt 11:064026. 2006..Nodular BCCs exhibit significantly lower absorption as compared to normal skin. Therefore, the spectral range between 1050 and 1400 nm appears to be optimal for nonmelanoma skin cancer detection...
- Multimodal confocal microscopy for diagnosing nonmelanoma skin cancersMunir Y Al-Arashi
Harvard Medical School, Boston, Massachusetts 02114, USA
Lasers Surg Med 39:696-705. 2007..In this study, the suitability of dye-enhanced multimodal confocal microscopy for the detection of nonmelanoma skin cancers was evaluated...
- Long-pulsed neodymium:yttrium-aluminum-garnet laser treatment for port-wine stainsMarjorie U Yang
Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
J Am Acad Dermatol 52:480-90. 2005..Laser treatment of port-wine stain (PWS) might be improved using a deeply penetrating wavelength...
- Photochemical repair of Achilles tendon rupture in a rat modelBarbara P Chan
Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
J Surg Res 124:274-9. 2005..Photochemical tissue bonding (PTB) is an emerging technique for bonding or sealing tissue surfaces that requires light and a photoactive dye for its effect. The potential of PTB for tendon repair was assessed in a rat model...
- Selective photothermolysis of lipid-rich tissues: a free electron laser studyR Rox Anderson
Wellman Center for Photomedicine, Harvard Medical School, Boston, Massachusetts, USA
Lasers Surg Med 38:913-9. 2006..In theory, infrared vibrational bands could be used for selective photothermolysis of lipid-rich tissues such as fat, sebaceous glands, or atherosclerotic plaques...
- Optical Mapping of Nonmelanoma Skin CancersAnna Yaroslavsky; Fiscal Year: 2005..v) Evaluate the clinical prototype and the developed imaging methods in a surgical practice environment. ..
- Towards In Situ Optical Pathology of Nonmelanoma Skin CancersAnna Yaroslavsky; Fiscal Year: 2008..The diagnostic application of this technology holds the potential to replace biopsy, thus reducing morbidity and time associated with that invasive procedure. ..