Dieter A Wolf

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Comparative proteomic and transcriptomic profiling of the fission yeast Schizosaccharomyces pombe
    Michael W Schmidt
    NIEHS Center for Environmental Health Proteomics Facility, Harvard School of Public Health, Boston, MA 02115, USA
    Mol Syst Biol 3:79. 2007
  2. pmc The fission yeast COP9/signalosome is involved in cullin modification by ubiquitin-related Ned8p
    C Zhou
    Department of Cancer Cell Biology, Harvard School of Public Health, Boston, MA, USA
    BMC Biochem 2:7. 2001
  3. ncbi Budding yeast Cdc6p induces re-replication in fission yeast by inhibition of SCF(Pop)-mediated proteolysis
    D A Wolf
    Department of Cancer Cell Biology, Harvard School of Public Health, Boston, MA 02115, USA
    Mol Gen Genet 262:473-80. 1999
  4. ncbi The COP9 signalosome: an assembly and maintenance platform for cullin ubiquitin ligases?
    Dieter A Wolf
    Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, MA 02115, USA
    Nat Cell Biol 5:1029-33. 2003
  5. ncbi BTB/POZ domain proteins are putative substrate adaptors for cullin 3 ubiquitin ligases
    Rory Geyer
    Department of Cancer Cell Biology, Harvard School of Public Health, Boston, MA 02115, USA
    Mol Cell 12:783-90. 2003
  6. pmc F-box-directed CRL complex assembly and regulation by the CSN and CAND1
    Michael W Schmidt
    Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, MA 02115, USA
    Mol Cell 35:586-97. 2009
  7. ncbi Fission yeast COP9/signalosome suppresses cullin activity through recruitment of the deubiquitylating enzyme Ubp12p
    Chunshui Zhou
    Department of Cancer Cell Biology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Mol Cell 11:927-38. 2003
  8. ncbi CSN facilitates Cullin-RING ubiquitin ligase function by counteracting autocatalytic adapter instability
    Susan Wee
    Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, MA 02115, USA
    Nat Cell Biol 7:387-91. 2005
  9. pmc Conservation of the COP9/signalosome in budding yeast
    Susan Wee
    Department of Cancer Cell Biology, Harvard School of Public Health, Boston, USA
    BMC Genet 3:15. 2002
  10. pmc Combinatorial diversity of fission yeast SCF ubiquitin ligases by homo- and heterooligomeric assemblies of the F-box proteins Pop1p and Pop2p
    Volker Seibert
    Department of Cancer Cell Biology, Harvard School of Public Health, Boston, MA, USA
    BMC Biochem 3:22. 2002

Collaborators

Detail Information

Publications16

  1. pmc Comparative proteomic and transcriptomic profiling of the fission yeast Schizosaccharomyces pombe
    Michael W Schmidt
    NIEHS Center for Environmental Health Proteomics Facility, Harvard School of Public Health, Boston, MA 02115, USA
    Mol Syst Biol 3:79. 2007
    ..This finding reaffirms at the protein level the considerable divergence in gene expression patterns of the two model organisms that was noticed in previous transcriptomic studies...
  2. pmc The fission yeast COP9/signalosome is involved in cullin modification by ubiquitin-related Ned8p
    C Zhou
    Department of Cancer Cell Biology, Harvard School of Public Health, Boston, MA, USA
    BMC Biochem 2:7. 2001
    ..pombe CSN, results in accumulation of Pcu1p exclusively in the modified form. However, it remained unclear whether this reflects global control of all cullins by the entire CSN complex...
  3. ncbi Budding yeast Cdc6p induces re-replication in fission yeast by inhibition of SCF(Pop)-mediated proteolysis
    D A Wolf
    Department of Cancer Cell Biology, Harvard School of Public Health, Boston, MA 02115, USA
    Mol Gen Genet 262:473-80. 1999
    ....
  4. ncbi The COP9 signalosome: an assembly and maintenance platform for cullin ubiquitin ligases?
    Dieter A Wolf
    Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, MA 02115, USA
    Nat Cell Biol 5:1029-33. 2003
    ..This apparent paradox can be resolved in a model that proposes CSN-mediated cullin inhibition is a prerequisite for the proper assembly and maintenance of active cullin ubiquitin ligase complexes...
  5. ncbi BTB/POZ domain proteins are putative substrate adaptors for cullin 3 ubiquitin ligases
    Rory Geyer
    Department of Cancer Cell Biology, Harvard School of Public Health, Boston, MA 02115, USA
    Mol Cell 12:783-90. 2003
    ..We propose that the BTB/POZ domain defines a recognition motif for the assembly of substrate-specific RING/cullin 3/BTB ubiquitin ligase complexes...
  6. pmc F-box-directed CRL complex assembly and regulation by the CSN and CAND1
    Michael W Schmidt
    Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, MA 02115, USA
    Mol Cell 35:586-97. 2009
    ..These findings were integrated into a refined model of CRL control in which substrate availability toggles CRLs between independent CSN and CAND1 cycles...
  7. ncbi Fission yeast COP9/signalosome suppresses cullin activity through recruitment of the deubiquitylating enzyme Ubp12p
    Chunshui Zhou
    Department of Cancer Cell Biology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Mol Cell 11:927-38. 2003
    ..We propose that CSN/Ubp12p-mediated deubiquitylation creates an environment for the safe de novo assembly of cullin complexes by counteracting the autocatalytic destruction of adaptor proteins...
  8. ncbi CSN facilitates Cullin-RING ubiquitin ligase function by counteracting autocatalytic adapter instability
    Susan Wee
    Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, MA 02115, USA
    Nat Cell Biol 7:387-91. 2005
    ..Our data suggest that maintenance of adapter stability is a general mechanism of CRL control by the CSN...
  9. pmc Conservation of the COP9/signalosome in budding yeast
    Susan Wee
    Department of Cancer Cell Biology, Harvard School of Public Health, Boston, USA
    BMC Genet 3:15. 2002
    ..CSN is highly conserved across species from fission yeast to humans, but sequence comparison has failed to identify the complex in budding yeast, except for a putative CSN5 subunit called Rri1p...
  10. pmc Combinatorial diversity of fission yeast SCF ubiquitin ligases by homo- and heterooligomeric assemblies of the F-box proteins Pop1p and Pop2p
    Volker Seibert
    Department of Cancer Cell Biology, Harvard School of Public Health, Boston, MA, USA
    BMC Biochem 3:22. 2002
    ..Both proteins interact with the cullin Pcu1p when overexpressed, but it is unknown whether this reflects their co-assembly into bona fide SCF complexes...
  11. ncbi Dynamic release of Cdc34 from SCF. the hand that rocks the cradle
    Dieter A Wolf
    Department of Cancer Cell Biology, Harvard School of Public Health, Boston, MA 02115, USA
    Cell 114:532-3. 2003
    ....
  12. pmc PCI proteins eIF3e and eIF3m define distinct translation initiation factor 3 complexes
    Chunshui Zhou
    Department of Genetics and Complex Diseases, Harvard School of Public Health, 665 Huntington Avenue, Boston, Massachusetts 02115, USA
    BMC Biol 3:14. 2005
    ..Interactions of unclear significance were reported between eIF3 subunits and PCI proteins contained in the CSN...
  13. ncbi Disruption of re-replication control by overexpression of human ORC1 in fission yeast
    D A Wolf
    Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Biol Chem 271:32503-6. 1996
    ..We propose that perturbation of the re-replication control by overexpression of HsORC1 is due to a titration of components involved in inactivating Cdc18p upon initiation of replication...
  14. pmc Rapid prefractionation of complex protein lysates with centrifugal membrane adsorber units improves the resolving power of 2D-PAGE-based proteome analysis
    Mary Kathryn Doud
    Harvard NIEHS Center Proteomics Facility, Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, USA
    BMC Genomics 5:25. 2004
    ..Nevertheless, the complexity of even the simplest proteomes limits the resolving power of 2D-PAGE. This limitation can be partially alleviated by sample prefractionation using a variety of techniques...
  15. pmc The F-box protein SKP2 mediates androgen control of p27 stability in LNCaP human prostate cancer cells
    Lifang Lu
    Department of Cancer Cell Biology, Harvard School of Public Health, Boston, USA
    BMC Cell Biol 3:22. 2002
    ..Here we used the human prostate cancer cell line LNCaP, which undergoes G1 cell cycle arrest in response to androgen, to examine the role of the SKP2 F-box protein in p27 regulation in prostate cancer...
  16. ncbi Multidimensional proteomic analysis of proteolytic pathways involved in cell cycle control
    Michael W Schmidt
    Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, USA
    Methods Mol Biol 241:235-45. 2004